Cns Agents - Straight Up Name + Class

Front 1

fluoxetine

Back 1

SSRI

prevents the reuptake of serotonin from synaptic cleft

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paroxetine

Back 2

SSRI

prevents the reuptake of serotonin from synaptic cleft

Front 3

sertraline

Back 3

SSRI

prevents the reuptake of serotonin from synaptic cleft

Front 4

fluvoxamine

Back 4

SSRI

prevents the reuptake of serotonin from synaptic cleft

Front 5

escitalopram

Back 5

SSRI

prevents the reuptake of serotonin from synaptic cleft

Front 6

citalopram

Back 6

SSRI

prevents the reuptake of serotonin from synaptic cleft

Front 7

desipramine

Back 7

Tricyclic Antidepressants

block reuptake of NE and serotonin from synaptic cleft. Also inhibit muscarinic, histamine and alpha adrenergic receptors leading to a slew of side effects.

Front 8

nortriptyline

Back 8

Tricyclic Antidepressants

block reuptake of NE and serotonin from synaptic cleft. Also inhibit muscarinic, histamine and alpha adrenergic receptors leading to a slew of side effects.

Front 9

imipramine

Back 9

Tricyclic Antidepressants

block reuptake of NE and serotonin from synaptic cleft. Also inhibit muscarinic, histamine and alpha adrenergic receptors leading to a slew of side effects.

Front 10

amitryiptyline

Back 10

Tricyclic Antidepressants

block reuptake of NE and serotonin from synaptic cleft. Also inhibit muscarinic, histamine and alpha adrenergic receptors leading to a slew of side effects.

Front 11

doxepin

Back 11

Tricyclic Antidepressants

block reuptake of NE and serotonin from synaptic cleft. Also inhibit muscarinic, histamine and alpha adrenergic receptors leading to a slew of side effects.

Front 12

trazodone

Back 12

Tricyclic Antidepressants

block reuptake of NE and serotonin from synaptic cleft. Also inhibit muscarinic, histamine and alpha adrenergic receptors leading to a slew of side effects.

Front 13

bupropion

Back 13

Tricyclic Antidepressants

block reuptake of NE and serotonin from synaptic cleft. Also inhibit muscarinic, histamine and alpha adrenergic receptors leading to a slew of side effects.

Front 14

venlafaxine

Back 14

Heterocylcic Antidepressant

Blocks the reuptake of neorepinephrine and serotonin from synaptic cleft (like TCA's!)

Front 15

trancylcypromine

Back 15

MAO inhibitors

when monoamine oxidase is inhibited, levels of serotonin, dpomanine and NE increase in the presynaptic neuron since MAO is a presynaptic enzyme responsible for metabolizing NE and serotonine and dpamine. The excess causes theneurotransmitters to leak out of the neuron into presynaptic space and activate serotonin and NE receptors.

Front 16

phenelzine

Back 16

MAO inhibitors

when monoamine oxidase is inhibited, levels of serotonin, dpomanine and NE increase in the presynaptic neuron since MAO is a presynaptic enzyme responsible for metabolizing NE and serotonine and dpamine. The excess causes theneurotransmitters to leak out of the neuron into presynaptic space and activate serotonin and NE receptors.

Front 17

isocarboxazid

Back 17

MAO inhibitors

when monoamine oxidase is inhibited, levels of serotonin, dpomanine and NE increase in the presynaptic neuron since MAO is a presynaptic enzyme responsible for metabolizing NE and serotonine and dpamine. The excess causes theneurotransmitters to leak out of the neuron into presynaptic space and activate serotonin and NE receptors.

Front 18

haloperidol

Back 18

typical antipsychotic agents

blocks postsynaptic dopamine D2 receptors in the limbic system of the brain, decreasing the respons of the postsynaptic neuron to dopamine excitation.

Front 19

fluphenazine

Back 19

typical antipsychotic agents

blocks postsynaptic dopamine D2 receptors in the limbic system of the brain, decreasing the respons of the postsynaptic neuron to dopamine excitation.

Front 20

chlorpromazine

Back 20

typical antipsychotic agents

blocks postsynaptic dopamine D2 receptors in the limbic system of the brain, decreasing the respons of the postsynaptic neuron to dopamine excitation.

Front 21

clozapine

Back 21

atypical antipsychotic agents

block both serotonin (5HT2) and dopamine receptors in the limbic system of the brain, thus decreasing the response of hte postsynaptic neuron to dopamine and serotonin excitation.

Front 22

risperidone

Back 22

atypical antipsychotic agents

block both serotonin (5HT2) and dopamine receptors in the limbic system of the brain, thus decreasing the response of hte postsynaptic neuron to dopamine and serotonin excitation.

Front 23

olanzapine

Back 23

atypical antipsychotic agents

block both serotonin (5HT2) and dopamine receptors in the limbic system of the brain, thus decreasing the response of hte postsynaptic neuron to dopamine and serotonin excitation.

Front 24

ziprasidone

Back 24

atypical antipsychotic agents

block both serotonin (5HT2) and dopamine receptors in the limbic system of the brain, thus decreasing the response of hte postsynaptic neuron to dopamine and serotonin excitation.

Front 25

aripriprazole

Back 25

atypical antipsychotic agents

block both serotonin (5HT2) and dopamine receptors in the limbic system of the brain, thus decreasing the response of hte postsynaptic neuron to dopamine and serotonin excitation.

Front 26

quetiapine

Back 26

atypical antipsychotic agents

block both serotonin (5HT2) and dopamine receptors in the limbic system of the brain, thus decreasing the response of hte postsynaptic neuron to dopamine and serotonin excitation.

Front 27

triazolam

Back 27

benzodiazepine, short acting (only one listed)

bind to site directly adjacent to GABA receptor and enhance the activity of the receptor, resulting in increased flow of chloride ion thru the channel leading to cell membrane hyperpolarization and decreased activity of the neurons fo the limbic, thalamic and hypothalamic regions of the CNS

Front 28

lorazepam

Back 28

benzodiazepine, intermediate acting

bind to site directly adjacent to GABA receptor and enhance the activity of the receptor, resulting in increased flow of chloride ion thru the channel leading to cell membrane hyperpolarization and decreased activity of the neurons fo the limbic, thalamic and hypothalamic regions of the CNS

Front 29

temazepam

Back 29

benzodiazepine, intermediate acting

bind to site directly adjacent to GABA receptor and enhance the activity of the receptor, resulting in increased flow of chloride ion thru the channel leading to cell membrane hyperpolarization and decreased activity of the neurons fo the limbic, thalamic and hypothalamic regions of the CNS

Front 30

alprazolam

Back 30

benzodiazepine, intermediate acting

bind to site directly adjacent to GABA receptor and enhance the activity of the receptor, resulting in increased flow of chloride ion thru the channel leading to cell membrane hyperpolarization and decreased activity of the neurons fo the limbic, thalamic and hypothalamic regions of the CNS

Front 31

chlordiazepoxide

Back 31

benzodiazepine, intermediate acting

bind to site directly adjacent to GABA receptor and enhance the activity of the receptor, resulting in increased flow of chloride ion thru the channel leading to cell membrane hyperpolarization and decreased activity of the neurons fo the limbic, thalamic and hypothalamic regions of the CNS

Front 32

diazepam

Back 32

benzodiazepine, long acting

bind to site directly adjacent to GABA receptor and enhance the activity of the receptor, resulting in increased flow of chloride ion thru the channel leading to cell membrane hyperpolarization and decreased activity of the neurons fo the limbic, thalamic and hypothalamic regions of the CNS

Front 33

clonazepam

Back 33

benzodiazepine, long acting

bind to site directly adjacent to GABA receptor and enhance the activity of the receptor, resulting in increased flow of chloride ion thru the channel leading to cell membrane hyperpolarization and decreased activity of the neurons fo the limbic, thalamic and hypothalamic regions of the CNS

Front 34

flurazepam

Back 34

benzodiazepine, long acting

bind to site directly adjacent to GABA receptor and enhance the activity of the receptor, resulting in increased flow of chloride ion thru the channel leading to cell membrane hyperpolarization and decreased activity of the neurons fo the limbic, thalamic and hypothalamic regions of the CNS

Front 35

phenobarbital

Back 35

barbiturates

interfere with electrolyte transport across neurla cell membranes and indirectly potentiate GABA receptor activity in the brainthus leading to hyperpolarization adn decreased activity of CNS neurons

Front 36

thiopental

Back 36

barbiturates

interfere with electrolyte transport across neurla cell membranes and indirectly potentiate GABA receptor activity in the brainthus leading to hyperpolarization adn decreased activity of CNS neurons

Front 37

pentobarbital

Back 37

barbiturates

interfere with electrolyte transport across neurla cell membranes and indirectly potentiate GABA receptor activity in the brainthus leading to hyperpolarization adn decreased activity of CNS neurons

Front 38

phenytoin

Back 38

it's own "class", standalone.

decreases the flow of sodium adn calcium ions acrosss the cell membrane thus decreased depolarization of the cells of the nervous system.

used to treat simple and complex partial seizures and generalized tonic clonic seizures and status epilepticus. Also trigeminal neuralgia adn torsades de pointes.

Front 39

valproic acid

Back 39

it's own "class", standalone.

unclear MOA

used for generalized tonic clonic seizures, moclonic seizures, absence seizures and treatment of mania ass with bipolar disorder and in prevention of migranes

Front 40

carbamazepine

Back 40

it's own "class", standalone.

inhibits flow of siodium ions thru sodium channels on neural cell membranes , thus causign hyperpolarization and decreased activity of neuron

used to treat ismple and complex partial seizures and generalized tonic clonic siezures and used in trigeminal neuralgia

Front 41

succinylcholine

Back 41

it's own "class", standalone.


is a depolarizing neuromuscular blocker that competes with ACh to reversibly bind to nicotinic receptors at the neuromuscular junction

Front 42

pancuronium

Back 42

nondepolarizing neuromuscular blocker that acts to competitively bind nicotinic receptors at the neuromuscular junction.

used as an adjunct to general anesthesia induction to reduce skeletal muscle contraction for facilitation of endotracheal intubation

Front 43

Gabapentin

Back 43

standalone. exact MOA unknown.

Used to treat postherpetic neuralgia,
partial seizures and chronic neuropathic pain

Front 44

lidocaine, procaine, cocaine

Back 44

local anesthetic agents

act by blocking sodium channels on neuronal cell membranes. used during minor surgical procedures where sensation needs to be blocked in a localized area of hte body, but unconsciousness is not necessary

Front 45

halothane

Back 45

general inhaled anesthetic

MOA not completely understood.

Used for general anesthetic induction and maintenance for surgical procedures

Front 46

isoflurane

Back 46

general inhaled anesthetic

MOA not completely understood.

Used for general anesthetic induction and maintenance for surgical procedures

Front 47

propofol

Back 47

general intravenous anesthetic agents

MOA unknown
Used for induction and maintenance of anesthesia and conscious sedation

Front 48

morphine

Back 48

opiod

produce analegesia by binding to specific opioid receptors located thru nervous system (mostly in brainstem, spinal cord, peripheral nerves, amygdala, thalamus and hypothalamus). Results in hyperpolarizationadn decreased activity of neural cells.

Used for pain control (morphine, fentanyl, codeine), cough suppression (codeine, dextromethorphan), diarrhea and acute pulmonary edema (morphine reduces anxiety and cardiac preload)

Front 49

codeine

Back 49

opiod

produce analegesia by binding to specific opioid receptors located thru nervous system (mostly in brainstem, spinal cord, peripheral nerves, amygdala, thalamus and hypothalamus). Results in hyperpolarizationadn decreased activity of neural cells.

Used for pain control (morphine, fentanyl, codeine), cough suppression (codeine, dextromethorphan), diarrhea and acute pulmonary edema (morphine reduces anxiety and cardiac preload)

Front 50

oxycodone

Back 50

opiod

produce analegesia by binding to specific opioid receptors located thru nervous system (mostly in brainstem, spinal cord, peripheral nerves, amygdala, thalamus and hypothalamus). Results in hyperpolarizationadn decreased activity of neural cells.

Used for pain control (morphine, fentanyl, codeine), cough suppression (codeine, dextromethorphan), diarrhea and acute pulmonary edema (morphine reduces anxiety and cardiac preload)

Front 51

hydrocodone

Back 51

opiod

produce analegesia by binding to specific opioid receptors located thru nervous system (mostly in brainstem, spinal cord, peripheral nerves, amygdala, thalamus and hypothalamus). Results in hyperpolarizationadn decreased activity of neural cells.

Used for pain control (morphine, fentanyl, codeine), cough suppression (codeine, dextromethorphan), diarrhea and acute pulmonary edema (morphine reduces anxiety and cardiac preload)

Front 52

hydromorphone

Back 52

opiod

produce analegesia by binding to specific opioid receptors located thru nervous system (mostly in brainstem, spinal cord, peripheral nerves, amygdala, thalamus and hypothalamus). Results in hyperpolarizationadn decreased activity of neural cells.

Used for pain control (morphine, fentanyl, codeine), cough suppression (codeine, dextromethorphan), diarrhea and acute pulmonary edema (morphine reduces anxiety and cardiac preload)

Front 53

heroin

Back 53

opiod

produce analegesia by binding to specific opioid receptors located thru nervous system (mostly in brainstem, spinal cord, peripheral nerves, amygdala, thalamus and hypothalamus). Results in hyperpolarizationadn decreased activity of neural cells.

Used for pain control (morphine, fentanyl, codeine), cough suppression (codeine, dextromethorphan), diarrhea and acute pulmonary edema (morphine reduces anxiety and cardiac preload)

Front 54

meperidine

Back 54

opiod

produce analegesia by binding to specific opioid receptors located thru nervous system (mostly in brainstem, spinal cord, peripheral nerves, amygdala, thalamus and hypothalamus). Results in hyperpolarizationadn decreased activity of neural cells.

Used for pain control (morphine, fentanyl, codeine), cough suppression (codeine, dextromethorphan), diarrhea and acute pulmonary edema (morphine reduces anxiety and cardiac preload)

Front 55

fentanyl

Back 55

opiod

produce analegesia by binding to specific opioid receptors located thru nervous system (mostly in brainstem, spinal cord, peripheral nerves, amygdala, thalamus and hypothalamus). Results in hyperpolarizationadn decreased activity of neural cells.

Used for pain control (morphine, fentanyl, codeine), cough suppression (codeine, dextromethorphan), diarrhea and acute pulmonary edema (morphine reduces anxiety and cardiac preload)

Front 56

dextromethorphan

Back 56

opiod

produce analegesia by binding to specific opioid receptors located thru nervous system (mostly in brainstem, spinal cord, peripheral nerves, amygdala, thalamus and hypothalamus). Results in hyperpolarizationadn decreased activity of neural cells.

Used for pain control (morphine, fentanyl, codeine), cough suppression (codeine, dextromethorphan), diarrhea and acute pulmonary edema (morphine reduces anxiety and cardiac preload)

Front 57

sumatriptan

Back 57

stimulates presynaptic 5-HT1D receptors

used for migranes and cluster HAs

Front 58

bupropion

Back 58

smoking cessation agent and antidepressant

acts to inhibit reuptake of NE and dopamine but also acts as a nicotinic antagonist at the nicotinic ACh receptors found in the brain. By binding at nicotinic receptors in that part of the brain, they block the ability of nicotine to stimulate the mesolimbic dopamine system (antagonism), thus interfering with teh reinforcement/reward loop experienced with smoking.

Front 59

varenicline

Back 59

smoking cessation agent

acts as partial agonist and antagonist at the nicotinic ACh receptors found in the brain. By binding at nicotinic receptors in that part of the brain, they block the ability of nicotine to stimulate the mesolimbic dopamine system (antagonism), thus interfering with teh reinforcement/reward loop experienced with smoking.

Front 60

buspirone

Back 60

standalone.

Acts at 5-HT1A presynaptic receptor partial agonist.

Treatment of deneralized anxiety disorder. Can also be used in conjunction with SSRIs in treating depression