Cms-Sepsis

Front 1

Define: Systemic Inflammatory Response Syndrome (SIRS)

Back 1

 SIRS is a widespread inflammatory response to a variety of severe clinical injuries

Front 2

Systemic Inflammatory Response Syndrome (SIRS) Criteria

Back 2

 Clinically indicated by the presence of 2 or more of the following:
 Temperature >38 C (100.4 F) or < 36 C (96.8 F)
 Heart rate > 90
 Respiratory rate > 20/min or PaCO2 < 32 mmHg
 WBC > 12,000 or < 4,000, or with > 10% immature (bands) forms (an increase in immature bands means a shift to the left indicating infection)

Front 3

Inflammation: Initiated by....

Back 3

Any type of injury:
 Microbial
 Mechanical (eg. Trauma)
 Thermal (eg, Burns)

Front 4

Define: Inflammation

Back 4

 Complex reaction to death or injury of cells or tissues

 Defense mechanism initiated to control and/or eliminate the offending agent and prepare an environment conducive to healing and repair

 Initiated by any type of injury

Front 5

Progression of Sepsis

Back 5

 Systemic Inflammatory Response Syndrome (SIRS)

 Sepsis

 Severe Sepsis

 Septic Shock

 Multiple Organ Dysfunction Syndrome (MODS)

Front 6

Severe Sepsis

Back 6

 Sepsis is considered severe when it is associated with organ dysfunction, hypotension, or hypoperfusion.

Front 7

Severe Sepsis: manifestations of hypoperfusion include....

Back 7

 Lactic acidosis
 Oliguria
 Acute alteration in mental status

Front 8

Septic Shock

Back 8

 Septic shock is sepsis with hypotension despite adequate fluid replacement combined with perfusion abnormalities

Front 9

Septic Shock Manifestations

Back 9

 Lactic acidosis
 Oliguria
 Acute alteration in mental status

Front 10

Multiple Organ Dysfunction Syndrome (MODS)

Back 10

Refers to the presence of altered organ function in an acutely ill patient that homeostasis cannot be maintained without intervention