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64 Cards in this Set

  • Front
  • Back
reach higer initial conc.



water soluble drug

digoxin
loading dose is less



water soluble

aminoglycoside(gentamiacin)
thyroid hormone, digoxin, warfarin, phenytoin

are all examples of

protein bound drugs
leads to decreased first pass metabolism and decreased rate of biotransofrat of some drugs
reduced hepatic mass and reduced hepatic blood flow
are distributed less wideley
water soluble
are distributed more wideley
fat soluble
leads to decreased renal eliminated of drugs and metabolies
reduced renal flow

low gfr


reduced elimination


decreased secreation function

sicca think which disease
sjorgens syndrome
droopy eyelids fat pads herniate, ectropion, entropin(lid inversion), as a result tear duct may be damaged leading to
keratoncinjt sicca
thickening and flatteing of cornea
astigmatism
anterior chamber volme decreases
glaucoma
vitrious humor loses water and accumulates



affecting vision

floaters
with lens issues in older ppl



protein changes increase densita opacit and yellowing




causing these 2 problems

cataracts and presbyopia




difficulty accommoadatig to near vision
presbyopia
leading cause of viosn loss in americans 60+
macular degeneration
less common of the 2, but responisble for the greatest loss of vision in elderly pts
wet(exudative/neovascularization
affects ppl over 75+



leading cause of vision loss in the world

cataracts
accounts for 30% acute hearing loss
cerumen impaction
bilateral symmetrical high frequency hearing loss
presbycusus
secondary to loss of hair cells in organ of corti
presbycusus
consantsn more difficult than vowels
presbycusus
decreased cough reflex



what's more likely?

aspiration
decreased bronchocilliary activitiy =
pneumonia
what happens to total lung capacity?
unchangeced
with respiratoy, complaints of this must be taken seroiously b/c as older may not develp this sympomt in late stage of illness
dyspnea
consider this when elderyl presetn with new syoms of wheezing or cough
gerd
with respiratoy



2 most common causes of death

pneoo

influenza

causes altered wave forms, incread aortic pulse wave
aortic stiff
increase systemic arterial pressure



decrease in diastolic pressure

increase ulse pressure
useful hemoydnyami indicator of vasucl stiffness
pulse pressure
max heart rate with exercise



increases or decresase?

decreases
this predisposes to Afib
decreased early diasotlic filling
decread early diastolic filling rate predisposes to
afib
clinical implicaito of ORTHOSTATIC hypotension
falls
most common abnormality
ekg changes
most common abnormaly on ekg in elderly



associted with drugs like digi, diruect or other anti arryhmti

non st changes
this drug class have a warning about qt interventral
fq
complaints are patholgic until proven otherwise
esophagus as insigan changes
swallowing disorders more comomon due to increased
dementia
seropositive evidence THIS is common,which leads to thinking of gastric mucosa and decrese in gastric acid production
h pylori
secondary to the increased use of nsaids and the increased prevalance of h pyloria infeciton
PUD
severe atrophic gastritis can result in diminsed product on intrisnt factor by y parietls cells



of this

vit b12 malasproitnts
no change in transit time or absort capacity



si vs li

si
slowing of transit time, results in constipation



si vs. li

li
solid vs liquid



food empytyin appears to be unaccted by age,

solid
solid vs liquid



food empytimy may be somewhat delay

liquid
assosicted with impaird phyisc activ, altered dieat and meticat
constipated
most common ab surgery in the eldery
gall blader surgery
with renal changes



prone to which type of natremia especially with

hyponatremia with diuretics
is incontinenc normal or not normal?
not normal
this leads to decreased complex learning and intellecutual performance
frontal lobe atrophy
WHAT MAY return in nervous system
primitive reflexes
with aging false postive with this test
rpr
this makes elarder more prone to dehyrdation
shrking pituatiry
is characterized by dry skin, pruritus, and crackling skin
xerosis
flattening of the dermo epiderm jx=
decubits ulcers
aka pressure sores
decutbits ulcers
decubits ulcers commonly occurs over
BONY prominces



sacrusm, heeals, anks, isch, greater trocange

which decubitsi ulcers?

stage




non blanchage erythema of an intact skin(reversible)

1
which decubitsi ulcers?stage



partial thinkc skin loss inovling the dermi or epiders, suprficial ulcer prsend asn abrasion blister or shallow crater(reversibe

2
which decubitsi ulcers?stage



full thicknesss skin loss, the subcuatinos tissue is visible in the wound




subcuant is damge or necorsi

3
which decubitsi ulcers?stage



fascia of underlying tissue is intact

3
which decubitsi ulcers?stage



full thinkc loss with eded in tou bbone or muscle

4
which 2 stages of decubit ulcers are reversible
1 and 2