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64 Cards in this Set
- Front
- Back
reach higer initial conc.
water soluble drug |
digoxin
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loading dose is less
water soluble |
aminoglycoside(gentamiacin)
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thyroid hormone, digoxin, warfarin, phenytoin
are all examples of |
protein bound drugs
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leads to decreased first pass metabolism and decreased rate of biotransofrat of some drugs
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reduced hepatic mass and reduced hepatic blood flow
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are distributed less wideley
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water soluble
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are distributed more wideley
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fat soluble
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leads to decreased renal eliminated of drugs and metabolies
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reduced renal flow
low gfr reduced elimination decreased secreation function |
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sicca think which disease
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sjorgens syndrome
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droopy eyelids fat pads herniate, ectropion, entropin(lid inversion), as a result tear duct may be damaged leading to
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keratoncinjt sicca
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thickening and flatteing of cornea
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astigmatism
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anterior chamber volme decreases
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glaucoma
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vitrious humor loses water and accumulates
affecting vision |
floaters
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with lens issues in older ppl
protein changes increase densita opacit and yellowing causing these 2 problems |
cataracts and presbyopia
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difficulty accommoadatig to near vision
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presbyopia
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leading cause of viosn loss in americans 60+
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macular degeneration
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less common of the 2, but responisble for the greatest loss of vision in elderly pts
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wet(exudative/neovascularization
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affects ppl over 75+
leading cause of vision loss in the world |
cataracts
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accounts for 30% acute hearing loss
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cerumen impaction
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bilateral symmetrical high frequency hearing loss
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presbycusus
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secondary to loss of hair cells in organ of corti
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presbycusus
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consantsn more difficult than vowels
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presbycusus
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decreased cough reflex
what's more likely? |
aspiration
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decreased bronchocilliary activitiy =
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pneumonia
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what happens to total lung capacity?
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unchangeced
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with respiratoy, complaints of this must be taken seroiously b/c as older may not develp this sympomt in late stage of illness
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dyspnea
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consider this when elderyl presetn with new syoms of wheezing or cough
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gerd
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with respiratoy
2 most common causes of death |
pneoo
influenza |
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causes altered wave forms, incread aortic pulse wave
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aortic stiff
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increase systemic arterial pressure
decrease in diastolic pressure |
increase ulse pressure
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useful hemoydnyami indicator of vasucl stiffness
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pulse pressure
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max heart rate with exercise
increases or decresase? |
decreases
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this predisposes to Afib
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decreased early diasotlic filling
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decread early diastolic filling rate predisposes to
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afib
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clinical implicaito of ORTHOSTATIC hypotension
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falls
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most common abnormality
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ekg changes
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most common abnormaly on ekg in elderly
associted with drugs like digi, diruect or other anti arryhmti |
non st changes
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this drug class have a warning about qt interventral
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fq
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complaints are patholgic until proven otherwise
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esophagus as insigan changes
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swallowing disorders more comomon due to increased
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dementia
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seropositive evidence THIS is common,which leads to thinking of gastric mucosa and decrese in gastric acid production
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h pylori
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secondary to the increased use of nsaids and the increased prevalance of h pyloria infeciton
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PUD
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severe atrophic gastritis can result in diminsed product on intrisnt factor by y parietls cells
of this |
vit b12 malasproitnts
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no change in transit time or absort capacity
si vs li |
si
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slowing of transit time, results in constipation
si vs. li |
li
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solid vs liquid
food empytyin appears to be unaccted by age, |
solid
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solid vs liquid
food empytimy may be somewhat delay |
liquid
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assosicted with impaird phyisc activ, altered dieat and meticat
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constipated
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most common ab surgery in the eldery
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gall blader surgery
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with renal changes
prone to which type of natremia especially with |
hyponatremia with diuretics
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is incontinenc normal or not normal?
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not normal
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this leads to decreased complex learning and intellecutual performance
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frontal lobe atrophy
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WHAT MAY return in nervous system
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primitive reflexes
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with aging false postive with this test
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rpr
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this makes elarder more prone to dehyrdation
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shrking pituatiry
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is characterized by dry skin, pruritus, and crackling skin
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xerosis
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flattening of the dermo epiderm jx=
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decubits ulcers
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aka pressure sores
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decutbits ulcers
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decubits ulcers commonly occurs over
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BONY prominces
sacrusm, heeals, anks, isch, greater trocange |
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which decubitsi ulcers?
stage non blanchage erythema of an intact skin(reversible) |
1
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which decubitsi ulcers?stage
partial thinkc skin loss inovling the dermi or epiders, suprficial ulcer prsend asn abrasion blister or shallow crater(reversibe |
2
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which decubitsi ulcers?stage
full thicknesss skin loss, the subcuatinos tissue is visible in the wound subcuant is damge or necorsi |
3
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which decubitsi ulcers?stage
fascia of underlying tissue is intact |
3
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which decubitsi ulcers?stage
full thinkc loss with eded in tou bbone or muscle |
4
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which 2 stages of decubit ulcers are reversible
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1 and 2
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