Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
13 Cards in this Set
- Front
- Back
|
What is the mean age of onset for Sjoren's?
what sex is most effective |
50
female |
|
|
In Sjoren's, there is lymphocyte infiltration of what?
|
exocrine glands
|
|
|
What autoantibodies are present in Sjoren's?
|
autoantibodies to riboncleoproteins Ro and La (SS-A and SS-B)
|
|
|
What are the most common presenting symptoms for Sjoren's
|
-dry mouth with difficulty swallowing
-burning, itching, and dry gritty eyes |
|
|
What other glands are also involved in Sjoren's?
|
exocrine glands of respiratory, vaginal, and Gi tracts
|
|
|
What type of anemia is present in Sjoren's?
|
normocytic normochronic anemia
|
|
|
What 2 things are elevated in Sjoren's?
|
ESR and CRP
|
|
|
What immunological tests are elevated in Sjoren's?
|
-Anti-Ro and Anti-La antibodies
-elevated Rh factor |
|
|
Findings of what support the dx of Sjoren's?
|
decreased flow on parotid and salivary scintigraphy
|
|
|
Tell me about the tx for Sjoren's syndrome
|
supportive
|
|
|
What are some complications to Sjoren's?
|
-lymphocyte infiltration of the lungs, kidney, muscles, and lymph nodes
-vasculitis -neurological deficits -lymphoma |
|
|
What are some neurological deficits found in Sjoren's?
|
-sensory neuropathy in both cranial and peripheral nerves
-neurogenic bladder -stroke -seizure -progressive transverse myelopathy |
|
|
Lymphoma as a complication to Sjoren's presents how?
|
as low grade B cell extranodal lymphoma
|
