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10 Cards in this Set
- Front
- Back
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What is psoriatic arthritis?
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inflammatory condition affecting the peripheral or spinal joints that occur in approximately 6% of cases of psoriasis
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cases of psoriasis
What are some clinical manifestations of psoriatic arthritis? |
-asymmetric oligoarthritides
-DIP joints only in some cases -symmetric RA mimic ¬-Arthritis Mutilans -enthesitis -tenosynovitis of hand flexor tendons -dactylitis -nail lesions |
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Tell me about the Arthritis Mutilans form of psoriatic arthritis.
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most destructive form with severe osteolysis that has telescoping of fingers and spinal involvement
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In most cases of psoriatic arthritis, what develops first, skin lesions or arthritis?
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-skin lesions
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What labs are usually negative and what are usually elevated in psoriatic arthritis?
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-negative (RF and ANA)
-elevated (ESR and CRP) |
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In severe cases, what can show on x-ray for psoriatic arthritis?
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pencil in a cup fingers because of acro osteolysis
-erosions and effusions in the absence of osteopenia -fluffy changes of periositis |
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What is the first line treatment for psoriatic arthritis?
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-acetaminophen
-NSAIDS |
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What is the tx for most severe forms of psoriatic arthritis?
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methotrexate
azathioprine sulfasalazine |
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What is the problem with antimalarias used to tx psoriatic arthritis?
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helps arthritis but can cause flare of dermatitis
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Name 2 other treatments for psoriatic arthritis and what they help with.
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-UV A light-used for dermatitis, but may help arthritis in peripheral joints
-Anti-TNF for skin and joints in pts unresponsive to other tx |
