Cm Iii-Dic

Front 1

DIC is characterized by what?

Back 1

-thrombosis and hemorrhage at the same time

Front 2

What are 2 common causes of DIC?

Back 2

-sepsis and trauma

Front 3

DIC is caused by activation of what?

Back 3

-coagulation, fibrinolytic system and platelet system
-results from activation of coagulation cascade due to exposure of blood to procoagulants

Front 4

Acute DIC:
1-associated with what?
2-most common symptom?
3-severe organ damage is caused by what?
4-thrombosis of what is rare
5-what causes jaundice
6-what CNS problems?

Back 4

1-associated with sepsis, trauma, and burns
2-most common symptoms is bleeding
3-organ damage is caused by microvascular thrombosis in arterial and venous system
4-major vessels is rare
5-hepatocellular dysfunction causes jaundice
6-coma, delirium, transient focal defects, meningeal signs

Front 5

Chronic DIC:
1-more or less common?
2-usually associated with what?
3-what is rare?
4-what is most common presentation?

Back 5

1-less common
2-associated with solid tumor, especially adenocarcinoma
3-bleeding is rare
4-MC presentation is DVT with or without PE and superficial migratory thrombophlebitis

Front 6

Dx of DIC:
1-what is seen on peripheral smear?
2-what is elevated?
3-what is decreased?
4-PT and PTT are what?

Back 6

1-schistocytes on peripheral smear
2-fibrin degradation products and d-dimer are elevated
3-fibrinogen is decreased
4-prolonged PT and PTT

Front 7

What is the tx for DIC?

Back 7

-replace platelet and clotting factors as needed
-tx underlying cause
-fibrinogen replaced with cryo; FFP for everything else