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11 Cards in this Set
- Front
- Back
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Beta lactam antibiotics: action and examples |
Inhibits penicllin binding protein, prevents crosslinking of peptidoglycans and cell wall synth. Penicillins, Cephalosporins |
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Tetracyclines
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eg Doxycyline
inhibits protein synth, act on 30s subunit |
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Glycopeptide antibiotics: action and examples |
attach to peptidoglycan precursors, prevent cross linking and cell wall synth. Vancomycin |
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Antibiotic targets |
Cell wall, protein synthesis, DNA synthesis, cell membrane |
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Macrolides |
eg Clarithomycin
inhibit protein synth, act on 50s subunit |
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Rifamycins |
eg Rifampicin inhibits protein synth, acts on mRNA |
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Potential new therapies |
Phage therapies, Monoclonal antibodies, Probiotics, Signal blockers |
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Sulphonamides |
eg Sulphamethoxazole Interfere with folate synth (Nucleotide synth) (inhibit dihydropteroate synthetase) |
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Aminoglycosides |
eg Gentamicin inhibit protein synth, act on 30s subunit |
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Trimethoprim |
Interfere with folate synth (Nucleotide synth) (inhibit dihydrofolate reductase) |
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Quinolones |
eg Ciprofloxaxin DNA gyrase inhibitor |
