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2471 Cards in this Set

  • Front
  • Back
What is pyrexia
Raised temperature
What is raised temperature called?
Pyrexia
What is enthesopathy?
Enthesopathies are disorders of peripheral ligamentous or muscular attachments to the bone
What is plantar digital neuritis?
Morton's neuroma
What is Morton's neuroma?
Plantar digital neuritis
What are one of the distinguishing features of gout?
Nocturnal pain
What can be a cause of nocturnal pain?
Gout
What can mask the inflammatory response to a fungal or skin infection and blur the distinctive border between infected and non-infected tissue?
Using a corticosteroid cream
What can using a corticosteroid cream do?
It can mask the inflammatory response to a fungal or skin infection and blur the distinction between infection and non-infection
What are the different rating scales for MRC muscle strength
0 No movement
1 Palpable contraction but no visible movement
2 Movement but only with gravity eliminated
3 Movement against gravity
4 Movement against resistance but weaker than the other side
5 Normal power
What is the MRC grading for muscle strength useful for?
It is suitable for patients with peripheral nerve damage causing muscle flaccidity. It is not a valid technique for patients with hypertonicity.
What should a clinical measurement be?
It should be accurate, precise, repeatable, reliable and valid
What is intraobserver reliability?
The same observer making measurements
What is it called when the same observer is making the measurements
Intraobserver reliability
What is interobserver reliability?
Different observers making the same measurement
What is it called when different observers make the same measurement?
Interobserver reliability
What is sensitivity?
The ability of a measurement or test to identify positive cases of the observation of interest
What is it called when a test or measurement identifies the positive cases of the observation of interest?
Sensitivity
What is specificity?
The ability of the measurement or test to exclude negative cases of the observation of interest
What is it called when a test or measurement excludes negative cases of the observation of interest?
Specificity
What are the systematic errors when taking a measurement?
1. Clinical environment
2. Procedure
3. Equipment
4. Practitioner
5. Patient
What can invalidate vibration testing?
Consumption of caffeine about an hour previous to the test.
What is cadence?
Steps per minute
What is the term for steps per minute?
Cadence
What is Morton's neuroma?
Morton's neuroma is a painful condition of the forefoot caused by a benign enlargement of (usually) the third common digital branch of the medial plantar nerve, located between and often distal to the 3rd and 4th distal metatarsal heads. The syndrome is a mechanical entrapment neuropathy with degenerative changes resulting from stretch and compression forces.
What are the symptoms of Morton's neuroma?
Sharp, throbbing pain which may radiate into adjacent areas. It is exacerbated by exercise and relieved by rest and massage. The condition can be present from about 4-6 months before the patient sees about it.
When can nail surgery be contra-indicated?
On a patient with a prosthetic joint. It may produce bacteraemia which could infect and loosen the joint replacement.
What is bacteraemia?
Bacteraemia is the presence of bacteria in the blood.
What is the presence of bacteria in the blood called?
Bacteraemia
What medication is contra-indicated when patients are asthmatic?
Aspirin or NSAIDs
What is a symptom of hepatitis?
Jaundice
What is jaundice a sign of?
Hepatitis
What are the signs that a patient could have deep vein thrombosis?
1. Oedema
2. Cigarette smoking
3. Use of the contraceptive pill
4. Recent immobilisation
What are symptoms of psoriasis and eczema?
Hypertrophy and anhidrosis of the skin
What can cause hypertrophy and anhidrosis of the skin?
Psoriasis and eczema
What is a symptom of Parkinson's disease?
Reduced facial expression
What can cause reduced facial expression?
Parkinson's disease or long-term use of psychotropic drugs eg pyschiatric medication
What is a symptom of long-term use of psychotrophic drugs?
Reduced facial expression
What is a symptom of a thyrotoxic patient?
Protruding eyes
What can cause protruding eyes?
Thyrotoxicosis
What do patients exhibit when on long-term steroid therapy?
A 'moon face'
What can cause a 'moon face'?
Long-term steroid therapy
What are the symptoms of hypothyroidism?
A loss of hair from the outer third of the eyebrows, baldness and coarse thickened facial skin
What can cause a loss of hair from the outer third of the eyebrows?
Hypothyroidism
What can cause baldness?
Hypothyroidism
What can cause coarse thickened facial skin?
Hypothyroidism
What is acromegaly?
Excess of growth hormone due to a disorder of the pituitary gland
What can an excess growth of hormone due to a disorder of the pituitary gland cause?
Acromegaly
What is a symptom of acromegaly?
A heavy 'lantern' jaw
What can cause a heavy 'lantern' jaw?
Acromegaly
What is salbutamol?
It is a beta-2 agonist used for the treatment of asthma
What side effects does salbutamol have on the lower limb?
Peripheral vasodilation
What effect can the contraceptive pill have on the lower limb?
Increased risk of DVT
What is chloramphenicol?
It is bacteriostatic antimicrobial
What is chloramphenicol used for?
It is used mainly for bacterial conjunctivitis
What effect can chloramphenicol have on the lower limb?
Peripheral neuritis
What is neuritis?
Inflammation of a nerve or group of nerves, characterized by pain, loss of reflexes, and atrophy of the affected muscles
What is colchicine?
It is used in the treatment of gout
What is the effect of colchicine on the lower limb?
It can cause sensorimotor neuropathy
What is metronidazole?
It is an antibiotic
What is metronidazole's mechanism of action?
It binds to DNA causing strand breakage
What is metronidazole used for?
It is used for the treatment of trichomonal infections, amoebic dysentry, giardiasis, gas gangrene, various abdominal infections, lung abcesses, dental sepsis and TB infection
What is the effect of metronidazole on the lower limb?
Sensorimotor neuropathy
What is indomethacin?
It is an NSAID
What is indomethacin used for?
It is used for acute attacks of gout and arthritis
What effect does indomethacin have on the lower limb?
Sensorimotor neuropathy
What are 4-quinolones?
The quinolones are a family of synthetic broad-spectrum antibiotics
What are the names of a 4-quinolone?
Ciprofloxacin, Clindomycin
What are 4-quinolones used to treat?
They are used in the treatment of pseudomonas, UTIs, chest, GU, GI infections and osteomyelitis
How do 4-quinolones work?
They inhibit DNA gyrase
What effect do 4-quinolones have on the lower limb?
They cause damage to epiphyseal cartilage and there is evidence to suggest they can also cause Achilles tendinopathy
What are corticosteroids?
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex
What is the action of corticosteroids?
They are anti-inflammatory by preventing phospholipid release, decreasing eosinophil action and a number of other mechanisms.
What is the effect of corticosteroids on the lower limb?
They can cause osteoporosis and skin atrophy. Inhaled corticosteroids have been implicated in achilles tendinopathy
What is aspirin?
It is an NSAID
How does aspirin work?
It acts by inhibition of cyclooxygenase, the enzyme that allows prostaglandin production
What effect does aspirin have on the lower limb?
It can cause purpura (bleeding into the skin)
What is frusemide?
It is a loop diuretic
What is frusemide used for?
Hypertension
What effect does frusemide have on the lower limb?
It can cause bullous eruptions
What is nalidixic acid?
Nalidixic acid is bacteriostatic and is the basis for the quinolones
What is the mechanism of nalidixic acid's action
It inhibits DNA gyrase
What is nalidixic acid used for?
Nalidixic acid is used mainly for urinary tract infections
What effect does nalidixic acid have on the lower limb?
Bullous eruptions
What is prednisolone?
Prednisolone is a steroidal anti-inflammatory
What is prednisolone used for?
Prednisolone is used in the treatment of RA
What effects can prednisolone have on the lower limb?
Prednisolone can reduce skin thickness and impair wound healing
What is bendrofluazide?
It is a thiazine diuretic
What is bendrofluazide used for?
It is used for hypertension
What effect can bendrofluazide have on the lower limb?
It can cause hyperuricaemia (high level of uric acid in the blood) which may result in gout
What effect can overdosing on Vitamins A and D do?
It can case ectopic calcification (pathologic deposition of calcium salts in tissues) in tendon, muscle and periarticular tissue
What can cause ectopic calcification (pathologic deposition of calcium salts in tissues)?
Overdosing on Vitamins A and D
What are the symptoms of anaphylaxis?
Hypotension, bronchiole constriction, laryngeal oedema, swelling of the tongue, urticaria, vomiting and diarrohea
What can overdosing with a LA cause?
Convulsions, hypotension and cardiovascular depression
What effects do amphetamines have on the lower limb?
They have a vasoconstrictive effect
What effect does tobacco have on the lower limb?
It can affect wound healing because of its vasoconstrictive effect and it can cause increased platelet adhesiveness and atherosclerosis
What effect does heavy alcohol consumption have on the lower limb?
It can effect peripheral sensation, immune response, postoperative wound healing and the metabolism of LAs as well as having implications for treatment compliance.
What effect can a hysterectomy have on the lower limb?
It can cause a hormone imbalance leading to osteoporosis
What are examples of inherited neurological diseases that affect the lower limb?
Friedrich's ataxia and Charcot-Marie-Tooth disease
What is Friedrich's ataxia?
Friedrich's ataxia is an inherited disease that causes progressive damage to the nervous system resulting in symptoms ranging from gait disturbance and speech problems to heart disease.
What are the effects of spina bifida occulta on the lower limb?
Impaired gait, pes cavus and plantar ulceration can happen in later life.
Who does thalassaemia mainly affect?
People of Mediterranean and South East Asian descent
What is CRAGCEL?
C Cardiovascular
R Respiratory
A Alimentary
G Genitourinary
C Central nervous system
E Endocrine
L Locomotor system
What two clinical syndromes does ischaemic heart disease refer to?
Angina pectoris and myocardial infarction
What causes angina?
Atherosclerosis of the arteries to the myocardium and often coexists with atherosclerois of the arteries to the lower limb
What is a myocardial infarction?
MI is a gross necrosis of the myocardium due to interruption of the blood supply to the area.
What is hypertension a risk factor for?
MI, renal failure and cerebral vascular accidents (strokes)
What is congestive heart failure (CHF)?
CHF results from the inability of the heart to sufficiently supply oxygenated blood to the tissues.
What can cause congestive heart failure (CHF)?
Causes can include valvular heart disease, myocardial disease and hypertension
What is rheumatic fever?
Rheumatic fever is a febrile disease (fever) occurring as a sequel to group A haemolytic streptococcal infections. It is characterised by inflammatory lesions of connective tissue structures especially of the heart and blood vessels and predisposes to bacterial endocarditis.
What happens in congested heart failure (CHF)?
There is an inadequacy in the supply of oxygenated blood. To compensate for this, first the heart rate and then the volume of blood filling the left ventricle increases. Because it takes longer to fill the left ventricle, the pressure in the whole cardiac pulmonary system 'backs up' causing pulmonary congestion, reduced blood gas exchange and eventually pulmonary oedema.
What are the signs and symptoms of congestive heart failure (CHF)?
Pulmonary oedema and shortness of breath.
What causes right-sided heart failure?
Right-sided heart failure is almost always associated with left-sided heart failure. The right side of the heart can no longer deal with the volume of venous blood returning to the heart for transportation to the lungs and a 'back up' of pressure occurs in the systemic circulation.
What is a cause of peripheral oedema?
Right-sided heart failure
How does right-sided heart failure cause peripheral oedema?
The 'back up' of pressure from the right side of the heart results in transudation of fluid into the peripheral connective tissue. Gravity will force most of the transudate to collect bilaterally in the feet and ankles. When the condition is chronic the odema will fibrose and the oedema is no longer relieved by elevating the legs.
What are the signs and symptoms of peripheral vascular disease?
1. get cramp at night
2. get muscle cramps while walking
3. suffer from chilblains
4. notice their feet change colour if it is particularly cold
What is a risk of sickle cell anaemia?
Use of tourniquets. A tourniquet causes relative anoxia and this in turn causes occlusion in small vessels due to changes in the haemodynamic qualities of red blood cells which may lead to small vessel infarction and possibly digital gangrene.
What is chronic bronchitis associated with?
Smoking and peripheral atherosclerosis
What drugs do gastric ulcers contra-indicate?
NSAIDs and analgesic preparations
What diseases are polyuria associated with?
Diabetes, cardiac failure or cortisol deficiency
What is a symptom of renal dysfunction?
Ankle oedema
What are the lower limb symptoms of Reiter's disease (reactive arthritis) (sexually transmitted infection)
Asymmetric arthralglia of the hip, knee, ankle and MTPJ, 'sausage toe', keratoderma blenhorragica (skin lesions)
What are the lower limb symptoms of HIV?
Karposi's sarcoma - a widespread skin or mucous membrane lesion appearing as a pink or red macule or violaceous plaques and nodules on the face, trunk and limbs. May appear wart-like.
What is the effect of gonococcal arthritis (sexually transmitted disease) on the lower limb?
Acute joint pain, swelling and stiffness. Usually accompanied by urethritis, dysuria and haemorrhagic vesicular skin lesions. Serious joint damage may result if the condition is not treated properly.
What is dysuria?
Painful urination
What are the 12 causes of peripheral neuropathy?
1. Nerve root compression of the sciatic or femoral nerve
2. Distal nerve compression of the popliteal, common peroneal and anterior tibial nerve
3. Hereditary neurological diseases eg Friedrich's ataxia, Charcot-Marie-Tooth disease
4. Endocrine eg diabetes mellitus, hypothyroidism, hypocalcaemia
5. Chronic alcohol abuse
6. Nutritional disorders eg pernicious anaemia, thiamine or Vit B6 deficiencies
7. Renal failure
8. Systemic disorders eg RA, SLE, vasculitis, sarcoidosis, amyloidosis
9. Infections eg TB, AIDS, leprosy, syphilis
10. Tumour eg bronchogenic carcinoma, myeloma, lymphoma
11. Toxic agents eg carbon monoxide, solvents, industrial poisons, lead
12. Medication eg isoniazid, metronidazole, nitrofurantoin
What is isoniazid?
Isoniazid is used in the treatment of mycobacterial infection
What is nitrofurantoin?
Nitrofurantoin is used to treat urinary tract infections
What are the three most common symptoms of diabetes?
Thirst, polyuria and weight loss
What other conditions can have the symptoms of thirst, polyuria and weight loss?
Diabetes insipidus, hypercalcaemia and renal failure
What are the six causes of thirst and polyuria?
1. Diabetes mellitus - osmotic diuretic effect of glucose
2. Diabetes insipidus - kidney disease prevents normal concentrating of urine or pituitary gland disorders cause a deficiency of antidiuretic hormone
3. Hypercalcaemia - result of hyperthyroidism where hypercalcaemia causes reversible impairment of renal concentrating mechanism
4. Hypocalcaemia - often a side effect of diuretic therapy it leads to impaired concentrating ability in the kidney
5. Excess salt intake - osmotic diuretic effect of increased sodium level
6. Renal failure - normal concentrating function of kidney lost
What are the 11 clinical features of hyperthyroidism?
1. Weight loss with a normal appetite
2. Heat intolerance
3. Fatigue
4. Cardiac palpitations
5. Irritability
6. Hand tremors
7. Sleep disturbance
8. Bulging eyes
9. Goitre
10. Diarrohea
11. Generalised muscle weakness
What 2 effects does hyperthyroidism have on the lower limb?
1. Infiltration of of non-pitting mucinous ground substance on the anterior surface of the tibia which causes intense itching and erythema. This so-called pretibial myxoedema (a confusing term since myxoedema suggests hypothyroidism) is more accurately described as an infiltrative dermopathy
2. Tarsal tunnel syndrome
What are the thyroid hormones called ?
Triiodothyronine (T3) and
Thyroxine (T4)
What are the features of hypothyroidism?
The facial expression is dull and the features puffy with swelling around the eye sockets due to infiltration of mucopolysaccharides. The eyelids will droop due to decreased adrenergic drive and the skin and hair will be coarse and dry. The tongue may be enlarged, the voice hoarse and speech slow. Tarsal and carpal tunnel syndrome, caused by infiltration of mucopolysaccharides are common clinical features.
Why is hypo- or hyperthyroidism contraindicated for nail surgery?
Because it reduces the patient's ability to deal with stress.
What are the parts of the adrenal gland?
The cortex and the medulla.
What does the adrenal cortex produce?
Glucocorticoids and mineralocorticoids
What is adrenal undersecretion called?
Addison's disease
What is adrenal oversecretion called?
Cushing's syndrome
What are the clinical features of Addison's disease
1. It is an autoimmune disease.
2. Reduction in the level of cortisol leading to reduced resistance to infection and trauma
3. Deficiency in mineralocorticoids and glucocorticoids
What are the clinical features of Cushing's syndrome?
Overproduction of glucocorticoids. High production of cortisol increases carbohydrate production and leads to trunal obesity and development of a moon face. Purple striae or stretch marks will develop on the abdomen. An increased production of androgens may cause hirsutism. Thinning of the skin and increased risk of infection are important lower limb features. Osteoporosis may occur as a sequel to disruption of normal kidney function. Secondary diabetes may also occur as a sequel to Cushing's syndrome.
What are the clinical issues of acromegaly?
Excess growth hormone leads to glycogenesis c 30% of acromegalics develop diabetes mellitus. Hypertension due to inadequate renal clearance of phosphates affects 30% of acromegalics. The majority of acromegalics suffer from headaches and joint pains.
Describe the atrium
The atrium is the upper chamber and a receiving vessel with a thin muscle wall or myocardium
Describe the ventricle
The ventricle is the lower chamber and because it is a dispersing vessel has much thicker muscle walls to generate propulsive forces
What are the two linings of the heart called?
The heart is lined by endocardium and surrounded by a tough pericardium.
What does endocardium do?
It forms the cusps of one-way valves (tricuspid and bicuspid) and semilunar valves
What forms the tricuspid, bicuspid and semilunar valves?
Endocardium
What do the tricuspid and bicuspid valves do?
They are one-way valves which control the flow of blood through the heart.
What do the semilunar valves do?
They control the entry of blood into the vessels leaving the heart
What valves are responsible for controlling the flow of blood through the heart?
The bicuspid and tricuspid valves
What valves control the entry of blood into the vessels leaving the heart?
The semilunar valves.
What does the right ventricle do?
It serves the pulmonary or minor circulation and sends deoxygenated blood via the pulmonary arteries to the lungs
What does the left ventricle do?
The left ventricle supplies the systemic or major circulation with oxygenated blood through the aorta to the body
What happens in the left atrium?
Oxygenated blood is returned from the lungs via the right and left pulmonary veins into the left atrium
What happens in the right atrium?
Deoxygenated blood from the body flows through the superior and inferior vena cavae into the right atrium
What are the layers of the arteries?
Tunica intima (inside), tunica media (middle), tunica adventitia (outside)
What lines the tunica intima?
Vascular endothelium
What does the vascular endothelium do?
Its cells secrete a variety of substances essential for maintenance of vessel wall and circulatory function
Where is the smooth muscle in an artery?
Tunica media
Which vessels have the greatest proportion of smooth muscle?
Arterioles
Why do arterioles have the greatest proportion of smooth muscle?
Because they have to change diameter
What do the arteries leaving the heart have the greatesst proportion of?
Elastic tissue
Why do arteries have a high proportion of elastic tissue?
Because they act as secondary pumps
How does blood reach the heart?
Blood is drained from the tissue bed by venules which join to form larger vessels called veins
What does vascular endothelium do in the veins?
It forms semilunar valves in the veins and venules
What do valves in veins prevent?
Backflow of blood
Where are veins found?
They are found either in the superficial fascia or deep in the muscle
What links the veins in the superficial fascia and deep in the muscle?
Communicating veins
What does a capillary do?
It links arterioles and venules
What links arterioles and venules?
Capillaries
What is a capillary made up of?
Thin-walled endothelium
What are metarterioles?
They are smooth muscle sphincters situated at the entrances to the capillaries and regulate blood flow into the capillaries
What regulates blood flow into the capillaries?
Metarterioles
What are A-V (arteriovenous) anastomases?
They are vessels which form a direct link between arterioles and venules and can bypass capillaries
What are A-V anastomases called when they form under the nail bed?
Glomus bodies or Sucquet-Hoyer canals.
What are glomus bodies?
A-V anostomases under the nail bed
What are Sucquet-Hoyer canals?
They are A-V anostomases under the nail bed
What is the microcirculation?
The smaller diameter vessels
What is the collection of smaller diameter vessels called?
The microcirculation
What are collaterals?
These are anastomases that provide an alternative circulation route for blood flow
What do lymphatic vessels do?
They drain the tissues and transport lymph through various lymph nodes eventually rejoining the peripheral circulation through the thoracic duct
What is tissue fluid?
It continuously forms from blood at capillary and postcapillary venular sites
How does tissue fluid move in and out of tissues?
Through hydrostatic and oncotic pressures
How does the body maintain the flow of blood around the body?
By altering the rate and force of contraction of the myocardium and by varying the diameter throughout the peripheral circulation
What are the two phases of the heart beat
Systole or contraction phase and diastole the relaxation phase
What is special about the myocardium and what is it called
It can contract without nerve pulses and this is called myogenicity
How does myogenicity work?
It is due to the presence of specialised 'pacemaker' cells which generate spontaneous action potentials.
Which is the most important action potential in the heart?
The sino-atrial node situated in the right atrium
What is the sino-atrial node?
It is the most important action potential in the heart and it is situated in the right atrium
Describe the route of an action potential in the heart
From the SA node to the AV node to the Bundle of His to the Purkinje fibres
How does the heart alter its activity according to the differing demands?
One way is through the autonomic system
How does the sympathetic nerve act on the heart?
Through beta 1 receptors
What are beta 1 receptors
They act on the heart through the sympathetic nerve
What is the beta 1 receptor's action on the heart?
Their action is to increase cardiac output by increasing stroke volume and heart rate
What is positive inotropy?
Increasing cardiac stroke volume
What is positive chronotrophy?
Increasing heart rate
How does the body increase cardiac output?
Through the beta 1 receptors, part of the sympathetic nerve
What two actions increase cardiac output?
Increasing stroke volume and heart rate
What is the parasympathetic nerve to the heart called?
The vagus
What is the vagus?
The parasympathetic nerve to the heart
What does the vagus do?
It causes slowing of the heart rate
What is slowing of the heart rate called?
Negative inotropy
What is negative inotropy?
Slowing of the heart rate
What does the vagus work on to cause slowing of the heart?
Cholinergic receptors
What do the sympathetic nerves do?
Speed things up
What do the parasympathetic nerves do?
Slow things down
What are cholinergic receptors?
They are acted on by the vagus to slow the heart down
What nerve from the ANS predominates at rest?
Parasympathetic nerve
What is the average resting heart rate?
72 beats per minute
Aside from activity, what cause a change in heart rate?
It is affected by posture, increasing on a change from supine to an upright position
What do baroreceptors do?
They regulate blood pressure
Where are baroreceptors situated?
In the arteries and veins
Where are the most important baroreceptors situated for controlling blood pressure?
In the aortic arch and carotid body
Where is the cardiovascular control centre?
The medulla oblongata in the brain stem
What muscle does the sympathetic nerve act upon in the arteries?
The smooth muscle in the tunica media
How do baroreceptors work in hypertension?
They rapidly adapt to a sustained change so that they are triggered by a higher than normal 'operating' range
What vessels respond to sympathetic tone?
All vessels except capillaries
What happens to the blood vessels when there is increased sympathetic tone?
Vasoconstriction
What is happening in the autonomic system when blood vessels constrict?
Increased sympathetic tone.
What happens to the blood vessels when there is decreased sympathetic tone?
Vasodilation
What is happening in the autonomic system when blood vessels dilate
Decreased sympathetic tone
Which vessels does the sympathetic nerve have the most effect on?
Arterioles
What has the greatest effect on arterioles?
The sympathetic nerves
Why do the sympathetic nerves have such a big effect on arterioles?
Because they have the highest proportion of smooth muscle in their walls
Which vessels have the highest proportion of smooth muscle in their walls?
Arterioles
What do arterioles have the most proportion of in their walls?
Smooth muscle
What are arterioles sometimes called?
The resistance vessels
What are the resistance vessels?
Arterioles
What vessels control homeostatic blood pressure and control distribution of the blood?
Arterioles
What do arterioles predominantly do?
Help control distribution of blood and homeostatic control of blood pressure
What organs help control blood volume?
Low pressure baroreceptors in the right atrium, kidneys as well as the CVS
What do kidneys assist with in the CVS?
They help control blood volume
What do the low pressure baroreceptors control?
They help control blood volume
Where are the baroreceptors that control blood volume?
In the right atrium
Which are the elastic arteries?
Aorta and pulmonary arteries
What do the aorta and pulmonary arteries have the highest percentage of in their walls?
Elastic tissue
How does the elastic tissue work in the aorta and pulmonary arteries?
They distend as the bolus of blood is received from the ventricles and act as a secondary pump during diastole when the elastic coil propels the blood forward
What are the only vessels not to deliver blood?
The capillaries
What does blood contain?
Dissolved nutrients, oxygen and hormones
What does blood take away?
Metabolic waste such as carbon dioxide and urea
What parts of the body is heat generated from?
Active muscles and the liver
What is the organ that controls heat loss?
The skin
What is a function of the skin?
Controlling heat loss
How does skin control heat loss?
It controls heat loss by superficial papillary loops and glomus bodies which can reroute blood towards or away from the skin surface
What is a function of a glomus body?
Glomus bodies can reroute blood towards or away from the skin surface
What is the function of the capillaries?
The exchange of the substances transported to the tissues by the blood
What happens to blood pressure when it enters the capillary beds?
There is a large drop in pressure
How is the blood pressure increased in veins and venules after leaving the capillary bed?
Semilunar valves, venoconstriction and the pumping action surrounding skeletal muscle on the deep veins as well as fluctuating negative pressures in the abdomen and thorax due to respiratory movements and the heart itself
Which part of the heart is venous blood drawn back into?
The atrial chambers
What is the blood returning to the heart called?
Venous return or preload
What is venous return?
Blood returning to the heart
What is preload?
Blood returning to the heart
What parts of the circulation should equal each other ?
Venous return should equal ventricular output
What is an intrinsic property of the myocardium?
Matching of venous return and cardiac output
Is the matching of venous return and cardiac output under nervous control?
No
What is Starling's law of the heart?
The matching of venous return to cardiac output
What is the matching of venous return to cardiac output called?
Starling's law of the heart
What are the consequences of unmatched venous return to cardiac output?
Congestive heart failure
How is congestive heart failure caused?
By unmatched venous return to cardiac output
What is the congestion due to in congestive heart failure?
It is due to a build up of blood throughout the venous tree due to a weak or damaged myocardium
In addition to returning blood to the heart, what else do veins do?
Because of their distensibility they act as capacitance vessels normally holding 3/5ths of the blood in the body
How much blood do the veins hold in the body?
They normally hold 3/5ths of the blood in the body
What is the purpose of the pulmonary circulation?
To deliver blood containing carbon dioxide to the lungs and exchange it for oxygen
What are the alveolar capillaries?
They exchange carbon dioxide for oxygen in the lungs
What is the interface between the lungs and the blood?
Alveolar capillaries
What is the advantage of having two separate circulations?
So they can act at different pressures
What are the two separate circulations?
The cardiac and pulmonary circulation
What do red blood cells contain?
Haemoglobin
What does haemoglobin do?
Picks up oxygen in the lungs in a stepwise manner and releases it in the tissues
What picks up oxygen in the lungs and releases it in the tissues?
Haemoglobin
What does the presence or absence of oxygen do to a haemoglobin molecule?
It changes its shape and changes its colour?
What colour is oxygenated blood?
What colour is deoxygenated blood?
Bright red
Bluish red
What causes blood to be bright red?
When it is oxygenated
What causes blood to be bluish red?
Deoxygenated blood
What are erythrocytes?
Red blood cells
What are red blood cells called?
Erythrocytes
Where are erythrocytes formed?
From stem cells in the red bone marrow
How do erythrocytes mature?
From the influence of hormones from the kidney called erythropoitins
What are erythropoitins?
They are hormones from the kidney
What do erythropoitins do?
They help mature erythrocytes
In addition to erythropoitins, what other factors are also needed for formation of the mature erythrocyte?
Iron, folic acid and Vitamin B12
How long does the erythrocyte circulate for?
120 days
What happens to the erythrocyte after it has circulated for 120 days?
It is broken down in the liver by phagocytic von Kupffer cells
What are von Kupffer cells?
They phagocytose erythrocytes in the liver
What is anaemia?
It is a reduction in the oxygen carrying capacity of the erythrocyte
What is a reduction in the oxygen carrying capacity of the erythrocyte called?
Anaemia
What causes aplastic anaemia?
Damage to the bone marrow by radiation can damage the stem cells or the young red blood cells
How does pernicious anaemia develop?
An autoimmune disease can destroy the parietal cells in the stomach leading to lack of Castle's intrinsic factor which causes an inability to absorb Vitamin B12
What vitamin is required for erythropoiesis and normal nerve function?
Vitamin B12
What does a deficiency of Vitamin B12 cause?
B12 is required for erythropoeisis and normal nerve function
What does the peripheral vascular system include?
Arteries, veins and lymphatics
What are the 7 cardiac conditions which may affect the lower limb?
1. Heart failure - left and/or right sided
2. Ischaemic heart disease - angina or myocardial infarction
3. Rheumatic fever
4. Myocarditis
5. Valve disorders - mitral stenosis, aortic stenosis, mitral regurgitation, tricuspid regurgitation
6. Infective endocarditis
7. Congenital heart disease - septal defects, valve defects, coarction of the aorta, Fallot's tetrology
What is coarction of the aorta?
A congenital condition whereby the aorta narrows in the area where the ductus arteriosus (ligamentum arteriosum after regression) inserts.
What is Fallot's tetrology?
A congenital condition which involves four abnormalities of the heart and is the most common cause of blue baby syndrom
What is ischaemia?
A condition which deprives the tissue of not only oxygen but nutrients and prevents removal of waste products
What is the condition which deprives the tissue of oxygen and nutrients and prevents the removal of waste products?
Ischaemia
What is the most common cause of ischaemic heart disease (IHD)?
Atherosclerosis of coronary vessels
What does atherosclerosis of coronary vessels cause?
Ischaemic heart disease (IHD)
What is ischaemic heart disease also called?
Coronary arterial disease (CAD)
What is coronary arterial disease (CAD) also called?
Ischaemic heart disease (IHD)
How do angiotensin converting enzymes (ACE) inhibitors work?
They interfere with the production of angiotensin 2 which is a powerful vasoconstrictor and triggers release of the hormone aldosterone from the adrenal cortex. Aldosterone promotes water and salt reabsorption from the kidney and inhibiting this hormone will reduce preload and cardiac output
How do diuretics act to reduce blood pressure?
They act on various parts of the kidney nephron to reduce water and salt reabsorption reducing preload and cardiac output
How do beta-blockers work to reduce blood pressure?
They prevent stimulatory action of endogenous catechoamines on the heart reducing cardiac output and blood pressure
How do calcium antagonists work to reduce blood pressure?
They act by interfering with the process of vascular smooth muscle contraction, reducing peripheral resistance and reducing blood pressure
What does angiotensin 2 do?
It is a powerful vasoconstrictor
What does aldosterone do?
It promotes water and salt reabsorption from the kidney
What are examples of ACE inhibitors?
Ramipril, Captopril
What are Ramipril and Captopril?
ACE inhibitors
What are examples of diuretics?
Bendrofluazide - thiazide diuretic and furosemide - loop diuretic
What are bendrofluazide and furosemide?
Bendrofluazide is a thiazide diuretic and furosemide is a loop diuretic
What are examples of beta blockers?
Atenolol, metaprolol and propranolol
What are atenalol, metaprolol and propranolol?
Beta blockers
What are examples of calcium channel antagonists?
Amlodipine and verapimil
What are amlodipine and verapimil?
Calcium channel antagonists
How is angina usually relieved?
Sublingual nitroglycerine
What is orthopnea?
Difficulty in breathing when supine
What are the main symptoms associated with anaemia?
Lassitude
What is pernicious anaemia associated with?
Peripheral neuropathy
What is sickle cell anaemia associated with?
Leg ulcers
What can anaemia trigger or make worse?
Angina pectoris, claudication or dementia
What are local factors that cause oedema in the lower limbs?
Trauma or occluded drainage vessels
What are central factors that cause oedema in the lower limb?
Congestive heart failure
How does congestive heart failure cause oedema in the lower limb?
Failure of the left ventricle to produce an adequate cardiac output causes backward pressure through the CVS which causes right ventricular failure. Right ventricular failure causes bilateral peripheral oedema in the lower limb
What oedema does left ventricular heart failure cause?
Left ventricular failure causes oedema in the pulmonary circulation
What causes oedema in the pulmonary circulation?
Left ventricular failure
What causes bilateral peripheral oedema in the lower limb?
Right ventricular failure
What does right ventricular failure do in the lower limb?
Causes bilateral peripheral oedema
What is another factor that can contribute to oedema in the lower leg besides right ventricular failure?
The renin-angiotensin-aldosterone system which is triggered by the low cardiac output causing renal retention of salt and water leading to a greater load on a failing heart
How can the renin-angiotensin-aldosterone system contribute to oedema?
Low cardiac output causes causes renal retention of salt and water leading to a greater load on the heart
What is central cyanosis?
Bluish discolouration of the lips, tongue and mucous membranes
What causes bluish discolouration of the lips, tongue and mucous membranes?
It indicates that arterial blood is inadequately oxygenated
What causes central cyanosis?
It can be due to deficiencies in the pump such as a congenital hole in the heart or cardiac failure or deficiencies in ventilation such as chronic obstructive airways disease
What can cause peripheral cyanosis of the toes and feet?
Severe cardiac and respiratory failure
What is koilonychia?
Spoon-shaped nails
What are spoon-shaped nails called?
Koilonychia
What causes koilonychia (spoon-shaped nails)?
Lack of iron can cause koilonychia of the finger, nails and a smooth red tongue
What is clubbing of the nails called?
Hippocratic nails
What are hippocratic nails?
Clubbing of the nails
What are hippocratic (clubbing of the) nails due to?
Subacute infective endocarditis or congenital cyanotic heart disease
What other factors can cause clubbing of the nails (hippocratic)?
Respiratory causes as well as bronchial carcinoma
What is vasculitis?
Inflammation of small vessels
What is inflammation of small vessels called?
Vasculitis
What are splinter haemorrhages associated with?
Vasculitis
Where are splinter haemorrhages usually found?
They usually appear near the nail margins
What may cause splinter haemorrhages?
Local causes may be digital septic thrombus. Systemic causes may be RA and they can also be caused by subacute bacterial endocarditis
What are symptoms of vascular problems?
Angina and myocardial infarction, dyspnoea (breathlessness) and lassitude
What are signs of vascular problems?
Oedema, cyanosis, pallor, koilonychia, hippocratic nails, splinter haemorrhages
What are clinical tests for vascular assessment?
Heart rate and blood pressure
What heart rate is classified as bradycardia
Less than 60 beats per minute
What is less than 60 beats per minute classified as?
Bradycardia
How many beats per minute would be classed as tachycardia?
Over a 100 beats per minute
What is over a 100 beats per minute classified as?
Tachycardia
What is an example of a physiological bradycardia?
A trained athlete
What is an example of a pathological bradycardia?
A complete heart block in the atrioventricular septum
What is sinus arrythmia?
It is a physiological arrhythmia associated with respiration seen mainly in young people. There is tachycardia on inspiration and bradycardia on expiration. It is thought to be due to the parasympathetic output to the heart
What drugs cause bradycardia
Beta blockers such as atenolol
What can cause tachycardia?
Hyperthyroidism can induce tachycardia
What can cause irregular or abnormal pulses (arrythmias)?
Physiological arrhythmia can be caused by exertion, training, age, anxiety or an underlying systemic condition such as thyroid disorders or medication such as beta blockers
What can cause a bounding pulse?
A response to stress, pyrexia, thyrotoxicosis or in hypoglycaemia
What is hypertension a risk factor for?
MI, left ventricular failure, cerebrovascular accidents, aortic dissection and renal failure
When is pressure highest in the arteries?
At ventricular systole when the blood is being forced into the arteries
When is pressure lowest in the arteries?
When the heart is relaxed just before its next contraction
What is a healthy adult's blood pressure
120/80 mm/Hg
What is pulse pressure?
The difference between the systolic and diastolic pressures
What causes pulse and systolic pressure to rise?
Age
Why does age cause pulse and systolic pressure to rise?
Because age causes loss of compliance in the tunica media
Name 5 errors that can happen whilst taking blood pressure
1. The rubber tubing may be perished
2. The valve may be faulty
3. The cuff may be the wrong size for the diameter of the limb
4. The arm may not be at heart level
5. The practitioner may not read the values correctly
What values are taken as being indicative of hypertension?
Over 160mm/Hg systolic, over 95mm/Hg diastolic
How many times should blood pressure be taken to decide whether the patient is hypertensive?
On three separate occasions
What are non-invasive hospital vascular assessments?
Electrocardiogram, chest x-ray, phonocardiography, echocardiography, electron beam tomogrophy
What does an electrocardiogram do?
The electrical activity of the heart is recorded using limb and chest leads attached to the skin. Many pathologies of the heart such as MI or ventricular enlargement in a failing heart will alter the normal PQRS waveform
What does an X-ray show in a vascular assessment?
Enlargement of the heart, calcification of coronary arteries or malignant masses
What does phonocardiography do?
It involves the application of a sensitive microphone to the chest wall to allow heart sounds and murmurs to be recorded. It is now being superceded by echocardiography
What does echocardiography do?
This uses ultrasound to visualise the heart and coronary arteries. It can visualise movement of ventricular walls, septum and heart valves
What does electron beam tomography do?
It is more sensitive in detecting patients at high risk of CAD than analysis of lipid or cholesterol levels
What are invasive hospital methods of vascular assessment?
Blood analysis, coronary angiography and myocardial perfusion scintigraphy
How can anaemia be diagnosed?
By a full blood count where the number and volume of the red blood cells is calculated as is the oxygen content
How can a blood test diagnose MI or angina?
During unstable angina or MI the ischaemic myocardial cells produce increased amounts of cardiac creatine kinase which peak 24 hours after the attack
What levels of LDL and HDL are considered to put a patient at risk of CAD?
LDL greater than 3.4mmol/l and HDL less than 0.9mmol/l are considered to have subclinical CAD
What is cardiac creatine kinase?
It is the enzymes produced by the ischaemic myocardium 24 hours after an angina attack or MI
What does coronary angiography do?
A diagnostic catheter is introduced through the femoral artery into the left ventricle and associated vessels. Pressures in the main chambers and vessels can be measured. Blood samples can be taken to measure oxygen content and ischaemic metabolites such as lactate and contrast cine-angiograms can be taken by injecting a radio-opaque dye at the site to be investigated
What is myocardial perfusion scintigraphy?
This is very sensitive imaging using radionuclides to detect CAD
What are the three causes of arterial insufficiency in the foot?
Acute, transient chronic
What are the acute causes of arterial insufficiency in the foot?
Extrinsic
1. Light clothing
2. Tourniquet
3. Plaster cast
4. Trauma
5. Frostbite
6. Immersion foot
Intrinsic
1. Thrombosis
2. Embolus
3. Ruptured aneurysm
4. Oedema
What are the transient causes of arterial insufficiency in the foot?
1. Raynaud's phenomenon
2. Chilblains
3. Hereditary cold fingers
What are the chronic causes of arterial insufficiency in the foot?
1. Atherosclerosis
2. Vasculitis
3. Thromboangitis obliterans (Buerger's disease)
4. Arteriosclerosis?
What is arteriosclerosis?
Arteriolosclerosis is any hardening (and loss of elasticity) of arterioles (small arteries).
What does peripheral arterial occlusive disease (PAOD) lead to?
Ischaemia and poor tissue viability
What is the most common cause of PVD?
Atherosclerosis
Describe the pathological process of atherosclerosis
This is a pathological process involving formation of a fatty plaque or atheroma in the intima of large and medium-sized arteries. The atheroma itself causes no obstruction to blood flow but its tendency to ulcerate promotes thrombus formation which causes narrowing (stenosis) or complete occlusion of the vessel. In addition the thrombus is likely to embolise and be swept away to cause obstruction further down the arterial tree.
Where does arteriosclerosis happen?
In retinal and renal vessels and do not have major complications in the foot
What are the less common causes of PVD?
Vasculitis, thromboangiitis obliterans and arterial emboli
What is thromboangiitis obliterans?
Thromboangiitis obliterans is a rare disease in which blood vessels of the hands and feet become obstructed. It mainly affects young males and has a very strong association with smoking. All signs and symptoms of arterial ischaemia and superficial phlebitis of the hands and feet may be present. Eventually distal necrosis occurs
What are some of the conditions associated with vasculitis?
RA, systemic lupus erythmatosus (SLE), polymyositis, dermatomyositis, systemic sclerosis, polyarteritis nodosa, giant-cell arteritis, erythema nodosum, Henoch-Schonlein syndrome
What is Henoch-Schonlein syndrome?
It is a systemic vasculitis characterized by deposition of immune complexes containing the antibody IgA in the skin and kidney. It occurs mainly in young children.
What is an arterial emboli?
Arterial emboli can be composed of any obstructive body that lodges in the smaller vessels of the arterial tree causing ischaemia distally
What is the most common embolus?
A fragmentation of a thrombus such as a mural thrombosis found on the endocardium especially around the heart valves or in the arteries mostly at sites of bifurcation where turbulence is most likely
What do emboli do?
They may occlude arterioles and capillaries causing isolated patches of digital necrosis
Where do emboli come from?
Septic thrombus from infection or deformed red blood cells as seen in sickle cell anaemia
What effects can cryovascular disorders such as Raynaud's and chilblains have on the lower limb?
Attacks of vasospasm may become chronic and cause painful digital ulceration
What does an inadequate blood supply lead to in the lower limb?
Pain
Pallor
Pulselessness
Paraesthesia
Paralysis
Perishing cold
What is the Fontaine classification of PVD?
1. Occlusive arterial disease but no symptoms (due to collaterals)
2. Intermittent claudication
3. Ischaemic rest pain (usually worse at night, relieved by dependency)
4. Severe rest pain with ulceration/necrosis (gangrene)
What is intermittent claudication an indication of?
An inadequate blood supply to the periphery
What makes intermittent claudication worse?
Exercise
What is the distance a patient can walk without ischaemic pain called?
Ischaemic or claudication distance
What can prevent intermittent claudication being felt?
Peripheral neuropathy
What alleviates night cramps?
Dangling the legs over the side of the bed or walking on a cool floor
How do night cramps happen?
The warmth of the bedclothes increases the metabolic rate of the tissues and increases the demand for oxygen which cannot be met and produces ischaemic pain. Using gravity to aid flow and cooling the limb helps to reduce metabolic activity
Which is the most severe condition of critical limb ischaemia?
Rest pain
How do peripheral tissues get blood during rest pain?
The legs must always lie below the level of the heart either by raising the head of the bed or by sleeping in a chair
How does the skin appear in PVD?
Thin, shiny and dry with absent hairs
What could be the cause of absent hairs on the leg other than PVD?
Friction from boots and depilatories
What does PVD do to muscles in the lower limb?
It can cause atrophy especially on the plantar surface of the foot
What are the characteristics of ischaemic ulcers?
1. They are caused by trauma
2. Very painful (unless there is neuropathy present)
3. Lack of granulation tissue
4. Low amounts of exudate
5. Slough is often present
6. Borders are well demarcated and they may have a punched out appearance
7. They often occur first under toenails, on the apices of the toes or around the border of the feet as a result of tight or ill-fitting footwear
8. Leg elevation can exacerbate the pain whereas lowering the leg into dependency can improve the blood supply and ease the pain
9. Ischaemic ulcers are unlikely to heal unless there is an improvement in blood supply
What medication can stop ulcers from healing?
Betablockers because they reduce cardiac output
How does blood supply affect the nails?
They may be crumbly, discoloured or thickened. They are prone to fungal infection and pitting
What is the DDX of crumbly nails affected by arterial insufficiency?
Psoriasis
What does necrosis or dry gangrene look like?
The tissue will appear hard, black and mummified with a clear demarcation line between dead and living tissue
What is usually NOT a symptom of poor peripheral arterial supply?
Oedema
What is the cause of unilateral or localised oedema?
Infection, trauma, allergy or impaired venous or lymphatic drainage
What does a pink skin mean?
Healthy circulation
What does white/pale skin mean?
Cold, anaemia,chilblains, Raynaud's, cardiac failure
What does white skin below demarcation line mean?
Severe ischaemia
What does blue skin mean (peripheral cyanosis)?
Cold, chilblains, Raynaud's, venous stasis
What does blue skin seen with central cyanosis mean?
Cardiac/respiratory failure
What does hazy blue skin mean?
Infection, necrosis
What are the six reasons for red skin?
Heat, exercise, extreme cold (cold-induced vasodilation), inflammation, infection (cellulitis), chilblains, Raynaud's
What does brown skin mean?
Haemosiderosis, moist necrosis
What does black skin mean?
Bruise, shoe dye, necrosis
What are the clinical tests for PVD?
Temperature gradient, capillary filling time, Buerger's elevation/dependency test, Allen's test, pedal pulses, bruits, Doppler ultrasound, claudication distance, ABPI
What is the difference in temperature that should be investigated between two legs?
A 2 degree difference in temperature should be investigated
How is Buerger's test done?
The leg should be elevated until all the veins in the dorsal arch of the foot have emptied. The plantar surface of the foot will appear pale. A mild pallor should be seen within 1 minute. A severe, wide-spread pallor is indicative of arterial insufficiency. The limb should be lowered into dependency and the time taken for the plantar surface to return to the colour of the other leg or for the dorsal veins to refill should be noted. Return to normal should be within 15 seconds, 20 seconds or more suggests that blood supply is inadequate and 40 seconds or more suggests severe ischaemia. If the skin is dusky red on dependency this is a serious sign indicating a severely compromised blood supply
What is Allen's test for?
To detect occlusion distal to the ankle
How is Allen's test done?
One leg of the patient is elevated and the dorsalis pedis artery is compressed. Maintaining pressure on the artery the leg is lowered into dependency. If the tibialis posterior artery is patent the foot should return to normal quickly. The patency of the dorsalis pedis artery can be tested by compressing the posterior tibial artery
What does oedema look like in cardiac failure?
It is bilateral, transudate, pitting, acquired, post myocardial infarction
What does oedema look like in venous stasis?
It is unilateral, transudate, pitting, acquired, post immobilisation
What does oedema look like in primary lymphoedema
It is bilateral, exudate, non-pitting, congenital
What does oedema look like in secondary lymphoedema?
It is unilateral, exudate, non-pitting unless very long-standing, acquired, post-infection, radiotherapy, surgery, malignancy
What is a bruit?
Bruits are abnormal sounds which can be heard using a stethoscope in the arteries
What causes bruits?
Bruits are due to turbulence in arteries caused either by an increased velocity or an obstruction
What are the three sounds in a triphasic pulse?
The first sound is the ejection of the ventricular bolus during systole. The second and third sounds are the diastolic sounds due to the reversal of flow caused by the elastic distension in the arteries and a final forward flow as the arteries rebound
What will a clinician be more likely to hear with a Doppler with a patient with bradycardia?
A weak triphasic sound
What will a clinician be more likely to hear with a Doppler with a patient with tachycardia?
Only a biphasic sound as the heart is beating too rapidly for reverse flow to occur.
How is the ABPI determined?
The reading for the ankle is divided by the brachial systolic reading
What is the average values for healthy adults with the ABPI?
0.98-1.31
What can a value of greater than 1 mean with the ABPI?
Calcification of the arteries
What is Monckberg's sclerosis?
Calcification of the tunica media of the muscular arteries
What does a value of less than 0.8 in the ABPI suggest?
There could be some obstruction in the more proximal part of the artery to the lower limb
What does a value of 0.75 or less in the ABPI indicate?
Severe problems
What does a value of 0.5 in the ABPI indicate?
Healing is unlikely to take place as the leg is in a pre-necrotic state
What other test besides ABPI can be used if there are calcification of the arteries?
The pole test
What hospital tests are used for testing macrocirculation?
Duplex ultrasound, angiography, MRI and PET scanning
What hospital tests are used for testing microcirculation?
Capillaroscopy, transcutaneous oxygen tension, photoelectric plethysmography, isotope clearance and Laser Doppler fluximetry
Why are hospital tests used?
1. Suitability for reconstructive surgery
2. The prognosis for the healing of ulcers
3. The level at which amputations should be performed
What does a duplex ultrasound do?
It gives an image of the artery and the flow within that artery and is non-invasive compared to contrast angiography
What does angiography do?
It is the gold standard for imaging the arterial supply of the lower limb. A needle is inserted into the femoral artery and a radio-opaque dye is injected just proximal to the occlusion. It can be used to:
1. locate occlusion and stenotic vessels
2. can determine whether a collateral circulation has been established
3. help determine the most appropriate revascularisation procedure
4. if a bypass procedure is to be performed it locates the site of the distal anastomasis
5. it is used to predict the prognosis for a limb salvage and graft patency
6. it can be used by the surgeon to have an accurate picture of distal run-off
What does MRI and PET scanning do?
They can be used to visualise various parts of the circulation but they are expensive and there are doubts as to whether they improve patient outcomes
What does capillaroscopy do?
The capillaries of the pedal nail fold can be examine using an oil immersion microscope under a strong light. In a healthy person the nutritive capillaries are distinct and well filled with blood but as ischaemia progresses the capillaries become hazy and less distinct. Capillaroscopy can be used to predict those patients likely to develop critical limb ischaemia and the likelihood of healing of ischaemic patients
What does the transcutaneous oxygen tension test do?
The skin is heated and the oxygen which diffuses to the surface of the skin is measured. It can be used as a predictor of level of amputation and of the success of angioplasty
What is photoelectric plethysmography?
It is used to measure skin blood pressure
What is isotope clearance?
It is used to measure skin perfusion pressure (SPP) and skin vascular resistance (SVR) in order to ascertain the likelihood of the healing of ischaemic ulcers.
What does Laser-Doppler fluximetry do?
It measures the movement of red blood cells in cutaneous vessels which changes as ischaemia progresses and can be used to determine amputation level
What are the three main pathological processes affecting veins?
1. Absent or incompetent valves
2. Formation of a thrombus which may trigger inflammation of the vein wall (thrombophlebitis)
3. inflammation of the vein wall (phlebitis) with possible secondary formation of a thrombus (phlebo-thrombosis)
What is phlebitis?
Inflammation of the vein wall
What is inflammation of the vein wall called?
Phlebitis
What is the formation of a thrombus which triggers inflammation of the vein wall?
Thrombophlebitis
What is thrombophlebitis?
Formation of a thrombus which triggers inflammation of the vein wall
What is inflammation of the vein wall with secondary formation of a thrombus?
Phlebo-thrombosis
What is phlebo-thrombosis?
Inflammation of a vein wall with a secondary formation of a thrombus?
Which veins do absent or incompetent valves affect?
Superficial or communicating veins
What are the causes of absent or incompetent valves?
1. Congenital
2. Increased pressure such pregnancy, abdominal tumour or ascites which causes venodilation and renders the valves incompetent
What conditions cause swelling or dilation of veins?
Congenital conditions
How does swelling or dilation of the veins cause pathology?
The resulting back flow due to gravity leads to increased hydrostatic pressure in the lower limb veins giving rise to the knotty appearance of varicose veins
What veins do inflammation of the vein walls affect?
Superficial or deep veins
What does deep vein pathology cause?
Superficial varicosities
What veins does phlebitis (inflmmation of the vein wall) affect?
Superficial veins
What is usually the cause of inflammation of the vein walls (phlebitis)?
Trauma or infection
What are the causes of venous thrombi?
1. Stasis
2. Hypercoagulability
3. Injury to the endothelium
What is Virchow's triad?
1. Stasis
2. Hypercoagulability
3. Injury to the endothelium
What are causes of venous insufficiency in the superficial veins?
1. Varicose veins - primary (idiopathic), secondary (backflow from deep to superficial vein)
2. Thrombophlebitis
3. Phlebangioma (congenital swelling of the vein)
4. Phlebectasia (congenital dilation of the vein)
What are causes of venous insufficiency in the deep veins?
1. Deep vein thrombosis due to - abnormalities affecting blood flow, abnormalities of clotting, abnormalities of endothelium
2. Idiopathic
3. Thrombophlebitis
What is phlebangioma?
Congenital swelling of the vein
What is congenital swelling of the vein called?
Phlebangioma
What is phlebectasia?
Congenital dilation of the vein
What is congenital dilation of the vein called?
Phlebectasia
What is Factor V Leiden?
It is the genetic tendency for hypercoagulation
What is the genetic tendency for hypercoagulation called?
Factor V Leiden
What are the symptoms of phlebitis in superficial veins?
The vein and surrounding area will be tender with erythema or cellulitis
What are the symptoms of thrombophlebitis?
The vein will be palpable as a linear, indurated cord and is usually associated with tenderness, erythema and warmth
What sensation is associated with problematic deep veins?
A bursting or aching associated with ankle oedema
What alleviates the pain of venous insufficiency?
Elevation of the leg
What are the symptoms of DVT?
DVT can be asymptomatic or it can be associated with tenderness, severe pain or warmth in the calf
What is the DDX for deep vein thrombosis?
A ruptured popliteal cyst as sometimes seen in RA
What diagnostic test would you NOT use if you suspected DVT
Homan's sign
Why would you not use Homan's sign if you suspected DVT?
Homan's sign increases pressure on the calf and increases the risk of embolism
What is Homan's sign?
Homans' sign is a sign of deep vein thrombosis (DVT). A positive sign is seen when present when passive dorsiflexion of the ankle by the examiner elicits sharp pain in the subject's calf.
Describe the route of venous emboli
Venous flow is proximal and central so venous emboli will be swept through increasingly larger vessels and emptied into the heart. From the heart it will enter the pulmonary circulation which is where the vessels are small enough to stop the embolus. It will then occlude one of the main pulmonary vessels (pulmonary embolism) preventing any gaseous exchange often with fatal consequences
Why does wear tight hosiery help with venous insufficiency?
The extra compression provided by the stocking aids venous blood flow and reduces peripheral oedema
What is telangiectasia?
It is dilated microvasculature
What does telangiectasia signify?
Telangiectasia around the medial malleolus indicates poor drainage
What colour does the skin go when there is stagnation of the blood in the lower limb?
Mottled cyanosis
What does mottled cyanosis of the skin of the lower limb signify?
Stagnation of blood in the veins as a result of poor drainage
What is atrophie blanche?
White patches on the skin around the ankles due to strangled microcirculation leading to fibrotic and sclerotic changes in the skin
Why does haemosiderin form?
Because of increased hydrostatic pressure
What is capillary hydrostatic pressure?
This pressure drives fluid out of the capillary and is highest at the arteriolar end of the capillary and lowest at the venular end
What is interstitial hydrostatic pressure
This pressure is determined by the interstitial fluid volume
What is capillary oncotic pressure?
The osmotic (oncotic) pressure within the capillary is principally determined by plasma proteins
What is interstitial oncotic pressure?
The oncotic pressure of the interstitial fluid depends on the interstitial protein concentration. The more permeable the capillary barrier is to proteins, the higher the interstitial oncotic pressure.
What are the DDX for haemosiderosis?
Erythema ab igne and necrobiosis lipoidica diabeticorum
What is erythema ab igne?
Erythema ab igne (EAI) is a skin reaction caused by chronic exposure to infrared radiation in the form of heat. It was once a common condition seen in the elderly who stood or sat closely to open fires or electric space heaters
What is necrobiosis lipoidica diabeticorum?
This is a condition associated with diabetes where yellowish patches are seen on the shins and the skin appears very transparent so that transparent blood vessels can be seen
What is the skin temperature likely to be in venous insufficiency?
Warm
What are the causes of varicose veins?
It may be due to incompetent valves in the superficial or communicating veins or as a consequence of DVT
How are varicose veins formed?
Back pressure due to an obstruction in the deep veins will accumulate through the communicating veins to the superficial veins. This causes the superficial veins to become incompetent and forward flow of blood is deficient. These veins are very extensible with non-uniform areas of weakness and have little support in the superficial tissues so they bulge unevenly due to the pressure of blood giving the knotted appearance of varicose veins
What is the sequelae of varicose veins?
Poor tissue viability which may lead to cellulitis or superficial phlebitis where the vein will be cord-like and painful
What are the consequences of poor drainage in the lower limb?
Poor drainage results in the accumulation of waste products which affects tissue viability. The skin may eventually become indurated.
What is indurated skin?
Deep thickening of the skin
What is gravitational (venous) eczema?
Signs of discolouration and pigmentation, scaly and lichenified skin in the presence of oedema, haemosiderosis and atrophie blanche. the area can be very pruritic and may lead to development of ulcers
What is another name for gravitational eczema?
Venous eczema
What medications do people with gravitational (venous) eczema often become sensitive to?
Topical antibiotics and to preservatives in other topical medicaments and bandages
Where are venous ulcers found?
Around the malleoli, particularly the medial malleoli but can spread completely around the leg. They form scars when healed.
What are venous ulcers associated with?
Post-thrombotic syndrome including gravitational (venous) eczema. They are rarely associated with superficial varicosities.
What do venous ulcers look like?
They are usually shallow with irregular borders and have either a healthy or slightly sloughy base unless infected
What does NOT necessarily cause a venous ulcer?
Trauma
When are venous ulcers painful?
They are usually painful only when have become infected.
How can the pain of venous ulcers be alleviated?
By elevation
Do these ulcers heal quickly?
No, they can hang around for years
What can make a venous ulcer heal more quickly?
Adequate compression
What should a practitioner be looking for in a long-standing venous ulcer?
Malignant changes such as squamous cell carcinoma
What are the signs of malignant change in an ulcer?
Rolled edges and a hyperplastic base
What is a hyperplastic base?
It is where the there is proliferation of cells over what would be expected in the base of an ulcer
How does oedema result?
Increased hydrostatic pressure causes leakage of tissue fluid
What is post-thrombotic syndrome?
Post-thrombotic syndrome refers to the long-term effects that can occur after venous thrombosis. It is also referred to as post-phlebitic syndrome.
What are the symptoms of post-thrombotic syndrome?
It is characterized by chronic pain, swelling, heaviness and other signs in the affected limb and in severe cases, venous ulcers may develop. It is the most common complication of deep venous thrombosis. Other complications may include purpura, eczematoid reaction, dermatitis, pruritis and ulceration
How does non-pitting oedema form?
Where the tissue fluid is an exudate it contains fibrinogen which will become organised
What is the tissue fluid called in pitting oedema?
Transudate
Why does transudate not become organised?
Because it does not contain fibrinogen but it may organise if it is very long-standing
Is the pitting due to DVT pitting or non-pitting?
It usually demonstrates pitting
What can oedema also cause if it forms around the ankles?
Ischaemia and occlude arteries which can cause moist gangrene if the occlusion is very severe
What sort of legs do people with chronic venous ulceration have?
Champagne or inverted bottle legs
What are champagne or inverted bottle legs indicative of?
Chronic venous ulceration
How does a clinician detect pitting oedema?
Digital pressure is firmly applied to the area for a period of 3-5 seconds. If an imprint of the fingers remain the oedema is described as pitting
What are the clinical tests to detect venous insufficiency?
Pitting/non-pitting oedema, Perthes test and Doppler
What is Perthes test?
With the leg dependent, on occlusion cuff is inflated at mid-thigh level. The superficial veins will become prominent as they fill. The patient is then asked to walk for 5 minutes. If the veins are healthy, the prominence will reduce due to drainage into the deep veins. If the superficial veins are incompetent the prominence will remain and if this is accompanied by a dusky rubor it suggests that the deep veins are incompetent
What is Perthes test used for?
It can be used to test the competency of leg veins.
What sound do veins give when heard through a Doppler?
They give a non-pulsatile, continuous, low-pitched sound like wind sighing down a chimney
Why do veins give a non-pulsatile continuous low-pitched sound?
Because of the effects of respiration on the flow of venous blood in the thorax.
When would a vein give a pulsatile sound?
When there is excessive fluid in the lower limbs as in congestive heart failure
What would a vein sound like if there is excessive fluid in the lower limb such as in congestive failure?
A pulsatile sound
What can a Doppler be used for in venous insufficiency?
To test for valvular incompetence of the calf veins
How could a clinician test for valvular incompetence of the calf veins?
By a Doppler
How does a clinician test for valvular incompetence of the calf veins by a Doppler?
With the patient standing and knee slightly flexed, the Doppler probe should be positioned over the vein in the popliteal fossa. The clinician should squeeze and release the calf distal to the probe. Two sharp sounds should be heard. The first sound is flow forward towards the probe as the vein is squeezed and the second sound is reverse flow due to gravity on release of the pressure. If there is no sound on compression this indicates a blockage between the site of compression and the probe. If the second sound is not abrupt but continues and fades away it suggests leakage of blood through the valves.
When should testing of valvular incompetence by a Doppler NOT be used?
When there is a high index of suspicion that there is a DVT
What are the hospital tests used to detect venous insufficiency?
Plethysmography, venous angiography and duplex ultrasound
What is plethysmography?
This test can be used to diagnose thrombotic obstruction of major proximal veins of the extremities
What can plethysmography NOT detect?
It is not useful for detecting calf vein thrombosis
What is venous angiography?
A radio-opaque dye is injected into the affected vein to show valvular incompetence and the presence of an obstruction
What does Duplex ultrasound do?
It can be used to ascertain whether the long saphenous vein is suitable for femoral bypass grafting as well as determining the presence of a thrombus
What do the lymphatic vessels do?
They play an important part in draining tissue fluid back, via the thoracic duct to the heart
What is it called when the lymphatic drainage is adversely affected?
Lymphoedema
What is lymphoedema?
When the lymphatic drainage is adversely affected
What is primary lymphoedema?
Primary lymphoedema is congenital
What is secondary lymphoedema?
Secondary lymphoedema is acquired
What are the causes of primary (congenital) lymphoedema?
1. Milroy's disease
2. Idiopathic
What are the causes of secondary (acquired) lymphoedema?
Intrinsic
1. Malignant neoplasia
2. Radiotherapy
3. Surgical excision of lymph nodes
4. Filariases
5. Infection
6. Pregnancy
Extrinsic
1. Trauma
2. Plaster cast
What is Milroy's disease?
Onset is either early in life or later in life at about the age of 35 years. It affects females more than males. Once it is organised it will not be alleviated by leg elevation
What is lymphoedema praecox?
Onset of lymphoedema early in life
What is lymphoedema tarda?
Onset of lymphoedema at the age of about 35 years
What are the signs of primary lymphoedema?
It begins as a soft, pitting form but becomes harder and non-pitting with time. It can be unilateral or bilateral
What are the signs of secondary lymphoedema?
Secondary lymphoedema is usually unilateral and considerable fibrosis may occur
How does lymphoedema affect tissue viability?
Tissue fluid stagnation will interfere with diffusion of gases and nutrients and removal of waste products which will affect tissue viability
What other pathologies are associated with lymphoedema?
Cellulitis and thickening and scaling of the skin leading to an "elephantiasis-like" appearance of the skin
What causes red streaks(lymphangitis) following the course of a vessel?
The presence of infection in the lymphatic vessels.
What are red streaks called following the course of the vessel?
Lymphangitis
What is lymphangitis?
Red streaks following the course of a vessel near infection
How would you find the popliteal vein with a Doppler?
Locate the popliteal artery and move the probe slightly sideways
What is lymphadenitis?
When infection reaches the lymph nodes/glands which will become tender and swollen
What is it called when infection in the lymph vessels reaches the lymph nodes/glands which become tender and swollen?
Lymphadenitis
What is it called when infection enters the bloodstream?
Bacteraemia
What sort of legs do people with chronic venous ulceration have?
Champagne or inverted bottle legs
What are champagne or inverted bottle legs indicative of?
Chronic venous ulceration
How does a clinician detect pitting oedema?
Digital pressure is firmly applied to the area for a period of 3-5 seconds. If an imprint of the fingers remain the oedema is described as pitting
What are the clinical tests to detect venous insufficiency?
Pitting/non-pitting oedema, Perthes test and Doppler
What is Perthes test?
With the leg dependent, on occlusion cuff is inflated at mid-thigh level. The superficial veins will become prominent as they fill. The patient is then asked to walk for 5 minutes. If the veins are healthy, the prominence will reduce due to drainage into the deep veins. If the superficial veins are incompetent the prominence will remain and if this is accompanied by a dusky rubor it suggests that the deep veins are incompetent
What is Perthes test used for?
It can be used to test the competency of leg veins.
What sound do veins give when heard through a Doppler?
They give a non-pulsatile, continuous, low-pitched sound like wind sighing down a chimney
Why do veins give a non-pulsatile continuous low-pitched sound?
Because of the effects of respiration on the flow of venous blood in the thorax.
When would a vein give a pulsatile sound?
When there is excessive fluid in the lower limbs as in congestive heart failure
What would a vein sound like if there is excessive fluid in the lower limb such as in congestive failure?
A pulsatile sound
How does lymphoedema affect tissue viability?
Tissue fluid stagnation interferes with diffusion of gases and nutrients and removal of waste products
What other pathologies are lymphoedema associated with?
Cellulitis and thickening and scaling of the skin which can lead to an "elephantiasis-like" appearance
What is lymphangitis?
The presence of infection in the lymphatic vessels.
What is presence of infection in the lymphatic vessels called?
Lymphangitis
What are the symptoms of lymphangitis?
Presence of red streaks following the course of the vessel.
What is lympadenitis?
Infection of the lymph nodes/glands
What is infection of the lymph nodes/glands called?
Lymphadenitis
What are the symptoms of lymphadenitis?
Swollen and tender lymph nodes
What is the condition called when infection enters the bloodstream?
Bacteraemia
What is bacteraemia?
When infection enters the bloodstream
What is septicaemia (blood poisoning)?
When bacteria enters the bloodstream causing systemic infection
What is the condition called when bacteria enters the bloodstream causing system infection?
Septicaemia or blood poisoning.
How would you find the popliteal vein with a Doppler?
Find the popliteal artery with the probe and move slightly sideways
What is yellow nail syndrome?
It is where the nail appears yellow, thickened but smooth and there is an increase in lateral curvature. There is also a reduced rate of growth.
What causes yellow nail syndrome?
The condition is associated with chronic lymphoedema
What can chronic lymphoedema cause in the nails?
Yellow nail syndrome
What are the hospital tests used for lymphoedema?
Lymphangiography and X-rays
What is lymphangiography?
It is the same technique as used for venous angiography
What do X-rays show in lymphoedema?
In primary lymphoedema they show hypoplasia of the lymphatic system and spidery and scanty lymphatic channels
What are the five most important signs that should alert the practitioner to further vascular assessment?
1. Absence of pedal pulses
2. ABPI of <0.9
3. Intermittent claudication
4. Oedema
5. A difference in temperature between the lower limbs of 2 degrees centigrade or more
What is the purpose of a neurological assessment?
1. establish which, if any, part of the nervous system is functioning abnormally
2. Identify the extent of the dysfunction
3. Where possible, arrive at a specific diagnosis
4. Draw up a treatment plan which takes account of the above information
What is a cerebral vascular accident (CVA)?
It is caused by haemorrhage, embolus or thrombus of the cerebral arteries
What is a stroke?
A cerebral vascular accident
What is an embolism?
An embolism occurs when an object (the embolus, plural emboli) migrates from one part of the body (through circulation) and causes a blockage (occlusion) of a blood vessel in another part of the body.
What is a thrombus?
A thrombus, or clot forms at the blockage point within a blood vessel
What is the difference between a thrombus and an embolism?
An embolism is carried to the site of occlusion whereas a thrombus forms at the site of occlusion
What is Parkinsonism?
A degeneration of dopaminergic receptors.
What can cause Parkinsonism?
It is usually idiopathic but can be drug induced
What is the condition called where there is haemorrhage, embolus or thrombosis of the cerebral arteries?
Cerebral vascular accident (CVA) or stroke
What is the condition called where there is a degeneration of dopaminergic receptors?
Parkinsonism
What is Friedrich's ataxia?
It is an inherited disorder affecting the cerebellum
When is the onset and what is the prognosis of Friedrich's ataxia?
Onset is in childhood and death is usually around 40 years
What is multiple sclerosis?
Patchy demyelination of the CNS which shows relapses and remissions
When is the onset of multiple sclerosis?
20+
What is the condition associated with patchy demyelination of the CNS which shows relapses and remissions?
Multiple sclerosis
What is poliomyelitis?
It is a virus that affects the (lower motor neurones) LMNs?
What is syringomyelia?
It is a progressive destruction of the spinal cord due to blockage of the central canal eg tumour
What is tabes dorsal?
It occurs with tertiary stage syphillis
What is spina bifida?
It is a defective closure of the vertebral column. It is congenital.
What is motor neurone disease?
It is degeneration of both upper motor neurones (UMNs) and lower motor neurones (LMNs). There is no sensory loss.
What age is the onset of motor neurone disease?
Between the ages of 40 and 60.
What causes motor neurone disease?
Idiopathic
What is generally the cause of death in motor neurone disease?
Death is usually due to respiratory infection
What is subacute combined degeneration of the spinal cord?
Due to lack of vitamin B12 and is usually seen in pernicious anaemia. It affects both sensory and motor tracts in the spinal cord. It is reversible if detected in time.
What is pernicious anaemia?
It is anaemia caused by a deficiency of vitamin B12. Vitamin B12 helps form red blood cells.
What is Charcot-Marie-Tooth disease?
It affects peroneal nerve and is predominantly motor with variable sensory deficit. It is the commonest inherited neuropathy and the onset is in teens and slowly worsens.
What are the other names for Charcot-Marie-Tooth disease?
Peroneal muscle atrophy or hereditary motor-sensory neuropathy
What is the name for the inherited disease that affects the peroneal nerve?
Charcot-Marie-Tooth disease
What is Guillain-Barre syndrome?
It is a post-viral autoimmune response. Predominantly motor effects with muscle weakness and paralysis but some sensory loss. 80% of patients show full recovery but there can be a chronic relapsing form. There is rapid onset and is potentially fatal due to respiratory failure
What is neurofibromatosis?
An inherited condition that leads to tumours of nerves and compression of the spinal cord
What pathologies can cause peripheral neuropathy?
Alcoholism, injury, diabetes mellitus
What is myasthenia gravis?
An inherited condition that affects the neuromuscular junction and leads to severe fatigue and weakness/paralysis
What are myopathies?
They are a range of relatively rare diseases affecting muscle only. They can be inherited or acquired. Symptoms are similar to LMN disease but no fasciculation
What is an ataxic gait?
An unco-ordinated gait
What is an unco-ordinated gait called?
An ataxic gait
What can cause an ataxic (unco-ordinated) gait?
It may be due to a disorder of the cerebellum or a lack of proprioceptive information
What are the initial clinical features of multiple sclerosis?
1. Double vision
2. Falling over
3. Tingling sensations
4. Loss of function
If a patient complains of double vision, falling over, tingling sensations and loss of function what could the pathology be?
Multiple sclerosis
What lower limb pathology are Guillan-Barre sufferers prone to?
Ulcers
What are the two types of cell that make up the tissue of the nervous system?
Glial cells and neurones
What are the four types of glial cells?
1. Ependymal
2. Oligodendrocytes (brain) and Schwann cells (periphery)
3. Astrocytes
4. Microglial
What types of cells are ependymal, oligodendrocytes (brain), Schwann cells (periphery), astrocytes and microglial?
They are glial cells.
What do ependymal cells do?
They are involved in the secretion and absorption of cerebrospinal fluid (CSF) which acts as an interstitial fluid bathing the cells of the brain and spinal cord
What are the cells called that are involved in the secretion and absorption of cerebrospinal fluid (CSF)?
Ependymal cells
What acts as the interstitial fluid of the brain and spinal cord called?
Cerebrospinal fluid (CSF)
What is cerebrospinal fluid (CSF)?
It acts as the interstitial fluid of the brain and spinal cord
What do oligodendrocytes in the brain and Schwann cells in the periphery do?
They are responsible for the manufacture of the myelin sheath around the axons of the neurones which improves the speed of nerve conduction. They also play a role in the development and repair of nervous tissue helping to guide the growing axons to their correct destination
What cells produce the myelin sheath around the axons of the neurones and help repair nervous tissue and guide the growing axons to their correct destination?
Oligodendrocytes in the brain and Schwann cells in the periphery
What are astrocytes and
what do they do?
-Act as buffers in the CSF, keeping K+ concentration constant.
-Play a Nutritive role
-Phagocytic
-Take up certain neurotransmitters
What are the cells called that keep K+ constant in the CSF, provide nutrients, are phagocytic and take up certain neurotransmitters?
Astrocytes
What do microglial cells do?
They are phagocytic and remove debris
What cells are phagocytic and remove debris?
Microglial cells
What is a function of glial cells?
Due to their sheer bulk they provide structural support as there is no connective tissue within the nervous tissue.
What cells provide structural support within the nervous tissue?
Glial cells
What happens when a neurone is damaged?
It cannot be replaced. Damage results in permanent changes.
How many parts does a neurone consist of and what are they?
1. Cell body
2. Dendrites
3. Axon
4. Presynaptic terminals
What is the function of a cell body in a neurone?
It contains the nucleus and other organelles and is the site of synthesis of chemicals (neurotransmitters) for the transmission of impulses.
What is the function of dendrites in a neurone?
Dendrites are fine branches from the cell body which are the chief receptive area for impulses from other neurones or for the reception of other stimuli
What is the function of an axon in a neurone?
This is the conducting portion and can be up to 1m in length. It conducts electrical impulses and is also involved in the transport of various substances to and from the cell body. It may be myelinated but if less than a micrometre in diameter it will be unmyelinated
What is the function of presynaptic terminals in the neurone?
These are fine branches of the axon which are responsible for the release of neurotransmitters to enable the impulse to pass from one neurone to the next or on to a muscle or gland
What is the gap or synapse between one neurone and the next called?
It is an area of physical discontinuity
Where is an area of physical discontinuity called?
It is the gap or synapse between one neurone and the next.
What is the anatomical classification of the nervous system?
The central nervous system (CNS), the peripheral nervous system (PNS) and muscle
What is the functional classification of the central nervous system?
The somatic nervous system, and the autonomic nervous system (ANS)
What is contained in the central nervous system?
All the structures lying within the central axis of the body ie the brain and spinal cord and it consists of neurones and glial cells
What are the three areas of the brain?
1. Forebrain
2. Midbrain
3. Hindbrain
What two structures are in the forebrain?
1. Cerebral cortex
2. Diencephalon
What structure is in the midbrain?
Corpora quadrigemina
What three structures are in the hindbrain?
1. Pons
2. Cerebellum
3. Medulla oblongata
What four structures are in the cerebral cortex?
1. Frontal lobe
2. Parietal lobe
3. Temporal lobe
4. Occipital lobe
What four structures are in the diencephalon?
1. Thalamus
2. Hypothalamus
3. Limbic system
4. Basal ganglia
What two structures are in the corpora quadrigemina?
1. Superior colliculi
2. Inferior colliculi
What is the function of the pons?
Modification of respiration
Where in the brain is respiration modified?
In the pons
What is the function of the cerebellum?
Modification of movement
Where in the brain is movement modified?
In the cerebellum
What is the function of the medulla oblongata?
It is a vital control centre
Where is the vital control centre of the brain?
In the medulla oblongata
What is the function of the frontal lobe?
Abstract thought, conscious action and speech
Where is the centre for abstract thought, conscious action and speech located?
In the frontal lobe
What is the function of the parietal lobe?
General senses, verbal understanding
Where is the centre for general senses and verbal understanding located?
In the parietal lobe
What is the function of the temporal lobe?
Hearing, taste, smell, emotions
Where is the centre for hearing, taste, smell and emotions?
In the temporal lobe
What is the function of the occipital lobe?
Vision
Where is the centre for vision located?
In the occipital lobe
What is the function of the thalamus?
It is a sensory relay station
Where is the sensory relay station located in the brain?
In the thalamus
What is the function of the hypothalamus?
Emotions, endocrine system, autonomic nervous system (ANS)
What is the centre for emotions, the endocrine system and the autonomic nervous system (ANS)?
The hypothalamus
What is the function of the limbic system?
It is the centre for motivation and emotions
Where is the centre for motivation and emotions?
In the limbic system
What is the function of the basal ganglia?
Movement
Where is the centre of movement in the brain?
In the basal ganglia
What is the function of the superior colliculi?
Visual orientation
Where is the centre for visual orientation in the brain?
In the superior colliculi
What is the function of the inferior colliculi?
Auditory orientation
Where is the centre for auditory orientation in the brain?
In the inferior colliculi
Where is the medulla oblongata located?
In the hindbrain
Where is the cerebellum located?
In the hindbrain
Where is the pons located?
In the hindbrain?
Where is the inferior colliculi located?
In the corpora quadrigemina
Where is the superior colliculi located?
In the corpora quadrigemina
Where is the corpora quadrigemina located?
In the midbrain
Where is the basal ganglia located?
In the diencephalon
Where is the limbic system located?
In the diencephalon
Where is the hypothalamus located?
In the diencephalon
Where is the thalamus located?
In the diencephalon
Where is the diencephalon located?
In the forebrain
Where is the occipital lobe located?
In the cerebral cortex
Where is the temporal lobe located?
In the cerebral cortex
Where is the parietal lobe located?
In the cerebral cortex
Where is the frontal lobe located?
In the cerebral cortex
Where is the cerebral cortex located?
In the forebrain
How many vertebrae surround the spinal cord?
32
What is the grey matter in the CNS formed from?
The cell bodies of the neurones
What is the white matter in the CNS formed from?
The axons form the white matter due to the presence of myelin
Where can lumbar punctures be performed without damaging the spinal cord?
At the level of L3 or L4
What are the nerves in the lower limb?
Lumbar plexus 1-4, femoral nerve, sacral plexus L4, L5, S1-3,hamstring nerve, sciatic nerve, common peroneal nerve, superficial peroneal nerve, tibial nerve, saphenous nerve and the deep peroneal nerve
What does the peripheral nervous system consist of?
Those nerves that lie outside the spinal cord and brain
What is the peripheral nervous system (PNS) divided into?
Afferent nerve fibres and efferent nerve fibres
What is the function of afferent nerve fibres?
They carry impulses towards the CNS from receptors such as warmth receptors
What is the function of efferent nerve fibres?
They carry impulses away from the CNS to effectors such as the leg muscles or sweat glands
How many pairs of cranial nerves are there?
12 pairs originating from the brain stem
How many pairs of spinal nerves are there?
31 pairs
How many roots do the spinal nerve emerge from the spinal cord as?
2 roots
What are the two roots of the spinal nerves that emerge from the spinal column called?
1. Dorsal (posterior) root
2. Ventral (anterior) root
What happens to the two roots of the spinal nerves after they have emerged from the spinal column?
They join to form the peripheral mixed spinal nerve which emerges between two adjacent vertebrae
What does the dorsal (posterior) root contain?
The cell bodies of afferent fibres
Where are the cell bodies of afferent fibres located in the dorsal (posterior) root?
They are located in a swelling called the dorsal root ganglion
What is a dorsal root ganglion?
It is a swelling in the dorsal root which contains the cell bodies of afferent fibres
Where does each afferent neurone travel into?
The dorsal horn
What is the dorsal horn?
The dorsal horn is where each afferent neurone travels into
What does the ventral (anterior) root contain?
Mainly efferent fibres
What is a dermatome?
it is defined as an area of skin supplied by a single nerve's dorsal root
What is the area of the skin supplied by a single nerve's dorsal root?
A dermatome
Where does S1 innervate?
The back of the foot up to just past the malleoli and the 4th and 5th toes and the skin superior to them up to the lateral malleolus
What dermatome innervates the back of the foot up to just past the malleoli and the 4th and 5th toes and the skin superior to them up to the lateral malleolus
S1
Where does L5 innervate?
The area from the 1st, 2nd and 3rd digits diagnonally across to the lateral malleolus to the lateral side just below the knee
What dermatome innervates the area from the 1st, 2nd and 3rd digits diagnonally across to the lateral malleolus to the lateral side just below the knee
L5
What does L4 innervate?
The medial side of the calf from below the knee to just below the medial malleolus
What dermatome innervates the medial side of the calf from below the knee to just below the medial malleolus
L4
What is the structure of skeletal muscle?
Elongated fibres, multi-nucleated syncytium with visible striations
What muscle has elongated fibres, multi-nucleated syncytium with visible striations
Skeletal muscle
What is a syncytium?
A multi-nucleate cell
What is the name for a multi-nucleate cell?
A syncytium
What innervates skeletal muscle?
Somatic nerves
What muscle do somatic nerves innervate?
Skeletal muscle
What is the function of skeletal muscle?
1. Moves bones
2. Functions as part of a motor unit
3. Cannot contract without a nerve impulse
4. Conscious control
What is the structure of cardiac muscular tissue?
It has branched fibres, a single nucleus per cell and visible striations
What muscular tissue has branched fibres, a single nucleus per cell and visible striations?
Cardiac muscular tissue
What innervates cardiac muscular tissue?
Autonomic nerves
What muscular tissue do autonomic nerves innervate?
Cardiac and smooth muscular tissue
What is the function of cardiac muscular tissue
It pumps blood, forms a functional unit, has myogenicity and unconscious control
What muscular tissue pumps blood, forms a functional unit, has myogenicity and unconscious control?
Cardiac muscular tissue
What structure does smooth muscular tissue have?
It has spindle-shaped fibres, a single nucleus per cell and no visible striations
What innervates smooth muscular tissue?
Autonomic nerves
What is the function of smooth muscular tissue?
It moves vessels, organs and glands. It forms functional sheets. There is myogenicity in some smooth muscles and has unconscious control
What muscular tissue moves vessels, organs and glands. It forms functional sheets. There is myogenicity in some smooth muscles and has unconscious control?
Smooth muscular tissue
What do the three main types of muscles depend on to initiate contraction?
The binding of calcium ions to calcium-binding proteins
What are the three main types of muscle?
1. Skeletal
2. Cardiac
3. Smooth
What happens when a muscle contracts?
Contraction or shortening involves the formation of crossbridges and sliding of actin and myosin myofilaments over one another
What is the somatic nervous system?
It includes all parts of the nervous system that deals with the conscious perception of stimuli and conscious action including the sensorimotor or conscious cortex
What is another name for afferent nerves?
Sensory nerves
What is another name for sensory nerves?
Afferent nerves
What is another name for efferent nerves?
Motor nerves
What is another name for motor nerves?
Efferent nerves
What is the autonomic nervous system (ANS)?
This is the part of the nervous system that deals with the internal organs
What parts of the brain are involved with the autonomic system?
The hypothalamus and the limbic system
What is the parasympathetic nervous system?
It is the efferent part of the autonomic nervous system which restores the 'status quo' and allows emptying actions
What neurotransmitter is released in the parasympathetic nervous system?
Acetylcholine
What is the sympathetic nervous system?
It is the efferent branch of the autonomic nervous system which prepares the body for action, the fight or flight response
What neurotransmitter is mainly released in the sympathetic nervous system
Noradrenaline or norepinephrine
Where do parasympathetic nerves innervate?
They do not innervate structures outside the central axis apart from blood vessels of the pelvic region
What structures do the sympathetic nerves innervate?
All peripheral structures including skin and blood vessels
In the lower limb what does sympathetic activity cause? and what does reduction of sympathetic activity cause?
Sympathetic activity causes peripheral vasoconstriction and a reduction in this activity or 'tone' causes vasodilation
How does a nerve impulse or signal work?
It is dependent upon the movement of ions across the cell membrane and through protein ion channels
What is an action potential?
It is used by the neurone to transmit an impulse over long distances
What is a graded potential?
A graded potential is the neurotransmitter crossing the synaptic gap to trigger an action potential in the next neurone. Graded potentials can only travel over very small distances and rapidly dissipate.
What potentials are affected by parkinsonism and myasthenia gravis and why?
They affect the graded potential because in parkinsonism there is loss of dopamine which is a neurotransmitter and with myasthenia gravis there is a loss of cholinergic receptors which affect the normal functioning of the graded potential
What are the differences between an action potential and a graded potential?
1. Action potentials have voltage-gated ion channels and graded potentials have chemically/mechanically/light-gated ion channels
2. A threshold must be reached before an action potential is generated. No threshold, all triggers will generate graded potentials
3. Action potentials are fixed magnitude (all or nothing). Graded potentials have magnitudes proportional to the size of the trigger
4. Action potentials have large potentials. Graded potentials have small potentials
5. Action potentials do not summate. Graded potentials do summate
6. Action potentials do not attenuate. Graded potentials rapidly attenuate
7. Action potentials are used for long-distance signalling. Graded potentials are used for local signals
What sense activates a mechanoreceptor?
Touch, pressure
Which receptor does touch, pressure activate?
Mechanoreceptors
What sort of nerve endings does a mechanoreceptor have?
Encapsulated and free nerve endings
What sense activates a thermoreceptor?
Warmth, cold
What receptor does warmth, cold activate?
Thermoreceptors
What nerve endings do thermoreceptors have?
Free nerve endings
What sense does a nociceptor pick up?
Pain
What receptor does pain activate?
Nociceptors
What sort of nerve endings do nociceptors have?
Free nerve endings
What is the function of a proprioceptor?
It detects position
What sort of nerve endings does a proprioceptor have?
Encapsulated nerve endings
What receptor detects position?
Proprioceptor
What are free nerve endings?
Free nerve endings are the branched terminations of the axons
What are encapsulated nerve endings?
Encapsulated nerve endings consist of branched axons enclosed in a discrete connective tissue capsule
What are baroreceptors?
Baroreceptors monitor changes in blood pressure
Where are baroreceptors located?
In the aorta
What are osmoreceptors?
Osmoreceptors monitor the osmolarity of the extracellular fluid
Where are osmoreceptors located?
In the hypothalamus
What receptors monitor changes in blood pressure?
Baroreceptors
What receptors monitor changes in osmolarity?
Osmoreceptors
What receptors register position sense, tension and degree of stretch?
Proprioceptors
What do proprioceptors register?
Proprioceptors register position sense, tension and degree of stretch
Where are proprioceptors located?
In the muscles, tendons and joints
Where do proprioceptors send their impulses to?
To the cerebellum and the somatosensory cortex
What is a sensory unit?
A sensory unit is the afferent nerve, its branches and the attached receptors
What is the area called that is served by a sensory unit?
The receptive field
What is a receptive field?
The area served by a sensory unit
What is somatotopic organisation?
This is where discrete areas of the cortex receive the information from the various parts of the body
What is the term for where discrete areas of the brain receive information from various parts of the body?
Somatotopic organisation
What are the two main ascending pathways?
1. The rapid, highly organised oligo-(few) synaptic pathways
2. The less well organised multisynaptic pathways
What tract carries pain information?
The lateral spinothalamic tract
Where does the lateral spinothalamic tract run?
It runs from the lateral region of the spinal cord up to the thalamus
What information does the lateral spinothalamic tract carry?
Pain information
What tracts carry proprioceptive information?
The spinocerebellar tract
What information does the spinocerebellar tract carry?
Proprioceptive information
Where does the spinocerebellar tract run to?
To the ipsilateral lobes of the cerebellum in the hindbrain
How many tracts does the oligosynaptic pathway consist of?
Two
What are the tracts that make up the oliogosynaptic pathway?
1. The dorsal (posterior) columns
2. The neospinothalamic tracts (part of the anterolateral tract)
What pathway does the dorsal (posterior) column and the neospinothalamic tract (part of the anterolateral tract) make up?
The oligosynaptic pathway
What is another name for the dorsal columns?
The posterior columns
What is another name for the posterior columns?
The dorsal columns
What is the neospinothalamic tract a part of?
The anterolateral tract
What is the anterolateral tract a part of?
The neospinothalamic tract
How many ascending tracts make up the multisynaptic pathway?
Two
What are the two tracts that make up the multisynaptic pathway?
1. Fasciculi propii tract
2. Paleospinothalamic tract
What pathway do the fasciculi propii tract and paleospinothalamic tract make up?
The multisynaptic pathway
What tracts carry information about touch?
The dorsal (posterior) column and the ventrospinothalamic tract
Why does a CVA affecting a particular part of the sensory cortex produce numbness or paraesthesia in a specific part of the body on the opposite or contralateral side?
Because the majority of ascending tracts cross over to the opposite side either in the spinal cord or in the brain stem.
What does ipsilateral mean?
Same side
What are the neurones called that are responsible for initiating commands in the brain?
Upper motor neurones (UMNs)
What is the function of an upper motor neurone?
UMNs are neurones responsible for initiating commands in the brain
How do upper motor neurones work?
They exert their influence via neurones in the ventral (anterior) horn of the spinal cord called lower motor neurones (LMNs)
Do upper motor neurones send impulses directly to muscles?
No
What is the function of lower motor neurones (LMNs)?
LMNs send impulses to the skeletal muscles via their axons.
What neurones send impulses to the skeletal muscles via their axons?
Lower motor neurones (LMNs)
What pathways do the axons of LMNs form?
They form the peripheral efferent pathways within the spinal nerves
How many tracts form the descending pathways?
Two tracts
What are the tracts that form the descending pathways?
1. The corticospinal tract
2. The multineuronal (brain stem) tract
What pathway does the corticospinal tract and the multineuronal (brain stem) tract form?
The descending pathways
What is the corticospinal tract responsible for?
The skilled movements of small, distal limb muscles such as those used in scalpel work
Where do most of the fibres of the corticospinal tract cross over?
They mainly cross over in the brain stem
What does the crossed over part of the corticospinal tract descend as?
The lateral corticospinal tract
What do the uncrossed fibres of the corticospinal tract descend as?
The ventral (anterior) corticospinal tract
Where do the upper motor neurones enter the spinal cord to synapse with the lower motor neurones?
The ventral horn of the grey matter
What is the corticospinal tract also known as?
The pyramidal tract
What is the pyramidal tract also known as?
The corticospinal tract
Why is the corticospinal tract known as the pyramidal tract?
Because the corticospinal tract forms a rough pyramid shape as it passes through the brain stem
Which of the descending tracts is the rapid pathway?
The corticospinal tract or the pyramidal pathway
Which of the descending tracts is the slower pathway?
The multineuronal tract or extrapyramidal pathway
What are multineuronal tracts also known as?
Extra (outside)-pyramidal pathways
Why are extra-pyramidal tracts so named?
Because these tracts do not form part of the pyramids in the medulla
What do extra-pyramidal (multineuronal) tracts influence?
1. The large proximal limb muscles
2. The axial muscles of posture
3. They have a predominantly inhibitory effect on the ventral horn cells
4. They are responsible for the antigravity reflexes which keep our knees extended and head erect to maintain upright posture
What influences are LMNs subject to?
They are subject to influences from neurones in the descending tracts and also spinal neurones
What is the final common pathway?
The peripheral pathway from LMN to skeletal muscle
What is the peripheral pathway from the LMN to skeletal muscle called?
The final common pathway
What is the motor unit?
The peripheral pathway from LMN to skeletal muscle, the neuromuscual junction and the skeletal muscle fibres innervated by the nerve.
What is the peripheral pathway from LMN to skeletal muscle, the neuromuscual junction and the skeletal muscle fibres innervated by the nerve?
The motor unit
What are the actions of the cerebellum?
The actions of the cerebellum are unconscious and are very important in postural reflexes
What part of the brain acts on postural reflexes?
The cerebellum
What descending pathways go from the cerebellum to the spinal cord?
No descending pathways go from the cerebellum to the spinal cord
Instead of descending pathways how does the cerebellum communicate?
By sending modifying influences to the sensori-motor cortex, the reticular formation and brain-stem nuclei
What is the reticular formation?
The reticular formation is a part of the brain (brain stem) which is involved in stereotypical actions, such as walking, sleeping, and lying down. It is absolutely essential for life.
What could cause symptoms of cerebellar defects?
Lesions in the
1. Ascending spinocerebellar tracts
2. Cerebellum itself
3. Efferent pathways going to other parts of the brain
What information does the cerebellum primarily receive?
Information on position sense from the ears, proprioceptors and the cerebral cortex
What are the functions of the basal ganglia?
The functions are unknown but are thought to enable abstract thought to be converted into voluntary action
Does the basal ganglia function at a conscious or unconscious level?
Unconscious level
What is the direct pathway from the basal ganglia to the LMNs?
There is no direct pathway to the LMNs from the basal ganglia
What areas of the brain does the basal ganglia influence?
The sensorimotor cortex and the descending reticular formation
What tract does the basal ganglia have the main influence on?
The descending extra-pyramidal (multineuronal) tracts
What are conditions called that affect the extrapyramidal system?
Extrapyramidal syndromes
What is an example of an extrapyramidal syndrome?
Parkinsonism
What syndrome is parkinsonism an example of?
Extrapyramidal syndrome
What are reflex actions?
They are automatic responses to particular stimuli and form the basis of much of our behaviour from the knee jerk to driving a car
What automatic responses are important in posture, balance and gait?
Reflexes
How do we get reflexes?
They can be inborn or acquired
What are examples of inborn reflexes?
1. Eye blink
2. Pupil dilation/constriction
3. Change in heart rate
4. Knee jerk (stretch) reflex
5. Pain withdrawal
6. Sweat secretion
What are examples of acquired reflexes?
1. Swimming
2. Walking
3. Driving
4. Debriding callus
What parts of the nervous system and effector organs can they involve?
They can involve any subdivisions of the nervous system and any type of effector organ
Which two systems are in close association in a reflex arc?
The nervous system and the endocrine system
What responses are produced in an inborn reflex?
Stereotypic responses which are usually protective reflexes or those responses needed for posture and balance
What does an acquired reflex involve?
They involve the conscious cortex and many different effectors and can be more easily modified
What is a reflex arc?
The pathway between a detector and effector and always involves the CNS but not necessarily the brain
What is the pathway between a detector and effector which involves the CNS but not always the brain?
A reflex arc
What are the three reflexes that are of particular importance to the functioning of the lower limb?
1. Pain withdrawal reflex
2. Crossed extensor reflex
3. Stretch reflex
What are the essential elements of a reflex arc?
1. A detector to detect the change (stimulus) in either the internal or external environment
2. Afferent neurones that send the information into the CNS along the afferent pathways.
3. An integrating centre to match the appropriate response to the stimulus. This will be in the brain or spinal cord. Different parts of the CNS communicate with one another via ascending and descending pathways
4. Efferent neurones that carry instructions from the CNS via efferent pathways to the effectors (skeletal, smooth or cardiac muscle or gland)
5. An effector to carry out the necessary response
Which two reflexes are often superimposed on each other?
The pain withdrawal reflex and the crossed extensor reflex eg withdrawing an injured limb during the pain withdrawal reflex while the remaining limb bears weight during the crossed extensor reflex
Besides being involved in the pain withdrawal reflex what else is the crossed extensor reflex involved in?
It is involved in each step in walking when one limb is in the swing phase and the other is weightbearing
What reflex is important in walking?
Crossed extensor reflex
What is a very important reflex in all motor activity especially when new actions are being learnt?
The stretch reflex
What is the stretch reflex particularly important for?
All motor activity and learning new actions
What reflex do the patellar and Achilles tendon reflexes demonstrate?
The stretch reflex
Where is the stretch reflex best demonstrated?
The patellar and Achilles tendon reflexes
What information does the stretch reflex supply?
It supplies the cerebellum with information about the state of contraction in muscle
What are the receptors called in the stretch reflex?
Stretch receptors
What are stretch receptors?
They are receptors in the stretch reflex
Where are stretch receptors located?
In specialised muscle fibres called intrafusal fibres
What are intrafusal fibres?
This is where stretch receptors are located
Where do receptors lie within intrafusal fibres?
They lie within swellings called muscle spindles within intrafusal fibres
What are muscle spindles?
Muscle spindles are swelling within intrafusal fibres where stretch receptors are located
What are extrafusal fibres?
Theyare ordinary muscle fibres
How does a stretch reflex work?
1. Ordinary muscle fibres (extrafusal fibres) are stretched when patellar tendon is hit by a hammer.
2. Stretch receptors generate graded potentials
3. These graded potentials trigger action potentials
4. Action potentials travel into the spinal cord and synapse with an alpha LMN
5. Efferent impulses travel out to the extrafusal fibres causing contraction of the muscle
How many types of stretch receptors are there?
Two
What are the types of stretch receptors
1. One conveys information about the degree of stretch (static)
2. The other conveys information about the rate of change of stretch (dynamic)
Which pathway does the information supplied by the stretch receptors go on?
The spinocerebellar pathway
What sites of the brain are involved in motor co-ordination?
How are these sites involved?
1. Premotor cortex - plans actions
2. Sensorimotor cortex - initiates action
3. Basal ganglia - converts thought into action
4. Cerebellum - Modifies action, compares actual and intended action, smooths action
5. Brain stem - modifies action, (extrapyramidal) - corrects position, (pyramidal) - skilled work
How is the premotor cortex involved in motor coordination?
It plans actions
How is the sensorimotor cortex involved in motor coordination?
It initiates action
How is the basal ganglia involved in motor coordination?
It converts thought into action
How is the cerebellum involved in motor coordination?
It modifies action, compares actual and intended action, smooths action
What function does the brain stem have on motor co-ordination?
It modifies action
What function does the extrapyramidal tracts have on motor co-ordination?
They correct position
What function do the pyramidal tracts have on motor co-ordination?
They are responsible for skilled actions
What part of the brain plans action in motor coordination?
The premotor cortex
What part of the brain initiates action in motor coordination?
The sensorimotor cortex
What part of the brain converts thought into action in motor coordination?
The basal ganglia
What part of the brain modifies action, compares actual and intended action and smooths action in motor coordination?
The cerebellum
What part of the brain just modifies action in motor coordination?
The brain stem
What tracts correct position in motor coordination?
The extrapyramidal tracts
What tracts promote skilled action in motor coordination?
The pyramidal tracts
Which part of the brain is primarily responsible for posture and balance?
The cerebellum
What is the cerebellum primarily responsible for?
Posture and balance
What parts of the brain are responsible for gait?
1. Premotor cortex
2. Sensorimotor cortex
3. Basal ganglia
4. Brain stem
5. Extrapyramidal tracts
6. Pyramidal tracts
7. Cerebellum
What are the causes of neurological disorders?
1. Heredity
2. Developmental defects
3. Trauma
4. Ischaemia
5. Compression
6. Infection
7. Autoimmune
8. Nutritional/metabolic
9. Iatrogenic
10. Idiopathic
What are the hereditary causes of neurological disorders?
1. Huntington's chorea
2. Peroneal muscular atrophy
3. Friedrich's ataxia
4. Malignant hyperpyrexia
What is malignant hyperpyrexia?
It is an inherited rare life-threatening condition that is triggered by exposure to certain drugs used for general anesthesia
What are the developmental defects that cause neurological disorders?
1. Spina bifida
2. Syringomyelia
What are the sorts of trauma that cause neurological disorders?
1. Severing of the spinal cord or a peripheral nerve
2. Concussion
What are the ischaemic causes of neurological disorders?
1. Stroke
2. Cerebral haemorrhage
What are the compression causes of neurological disorders?
1. Tumour of the cerebellum
2. Morton's neuroma
3. Common peroneal nerve palsy
What are the infective causes of neurological disorders?
1. HIV
2. Jakob-Creutzfeld disease
3. herpes zoster (shingles)
4. Guillain-Barre syndrome
5. lepromatous neuropathy
What are the autoimmune causes of neurological disorders?
1, Myasthenia gravis
2. Polymyositis
3. Possibly multiple sclerosis
What are the nutritional/metabolic causes of neurological disorders?
1. Korsakoff's psychosis
2. Sub-acute combined degeneration of the spinal cord
3. Diabetic neuropathy
What is Korsakoff's psychosis?
It is a brain disorder caused by the lack of thiamine (vitamin B1) in the brain
What is sub-acute combined degeneration of the spinal cord?
Subacute combined degeneration of spinal cord, also known as Lichtheim's disease refers to degeneration of the posterior and lateral columns of the spinal cord as a result of vitamin B12 deficiency. It is usually associated with pernicious anemia.
What are iatrogenic causes of neurological disorders?
1. Tight plaster cast causing nerve palsy
2. Drug-induced myopathies such as lithium and high-dose steroids
What are idiopathic causes of neurological disorders?
1. Parkinson's disease
2. Motor neurone disease
3. Non-familial Alzheimer's disease
What is mononeuropathy?
It is abnormality of a single nerve
What is abnormality of a single nerve called?
Mononeuropathy
What is mononeuritis multiplex?
It is assymetric abnormality of several individual nerves
What is assymetric abnormality of several individual nerves?
Mononeuritis multiplex
What is radiculopathy?
Abnormality of a nerve root
What is abnormality of a nerve root?
Radiculopathy
What is polyneuropathy?
Widespread, symmetrical abnormality of many nerves, usually characterised as sensory/motor/autonomic 'glove and stocking' distribution
What is widespread, symmetrical abnormality of many nerves, usually characterised as sensory/motor/autonomic 'glove and stocking' distribution?
Polyneuropathy
What may occlusion of the posterior cerebral artery cause?
It may cause visual disturbance
What artery feeds the occipital lobe of the brain?
The posterior cerebral artery
What vascular disturbance may cause visual disturbance?
Occlusion of the posterior cerebral artery
What part of the brain does the posterior cerebral artery feed?
The occipital lobe
What could cause ataxia?
Occlusion of the cerebellar artery
What could occlusion of the cerebellar artery cause?
Ataxia
What might occlusion to the vasa nervosum of a peripheral nerve cause?
'Glove and stocking' paraesthesia
What could cause 'glove and stocking' paraesthesia?
Occlusion of the vasa nervosum of a peripheral nerve
What is a vasa nervosum?
Blood vessels to the nerves
What five things would assessment of neurological function include?
1. Levels of consciousness
2. Sensory function
3. Motor function (to include muscles)
4. Posture and coordination
5. Autonomic function
What nerve axons are most often affected in multiple sclerosis?
The optic nerves, the cerebellar nerves and the nerves of the lower spinal cord
What are the symptoms of multiple sclerosis?
1. Blurring of vision (diplopia)
2. Unsteady gait
3. Weakness in the lower limbs
4. Lower limb sensory loss
5. Disturbances of micturition (urination)
What is diplopia?
Blurring of vision
What is blurring of vision?
Diplopia
What is micturition?
Urination
What is another word for urination?
Micturition
What are the three most common diseases to affect the CNS?
1. Stroke
2. Parkinson's disease
3. Multiple sclerosis
What is the onset of Guillain-Barre syndrome?
It has a sudden postviral onset
What is paresis?
Weak, sluggish or paralysed
What is the term for weak, sluggish, paralysed?
Paresis
What would a slow progressive onset of muscular weakness suggest?
Muscular dystrophy
What would an acute onset of muscular weakness suggest?
A demyelinating disease
What would continuous pain, numbness, a sensation of heaviness or a 'pins and needles' sensation in the arm not associated with exercise suggest?
These symptoms could be due to compression of nerve roots in the spine eg cervical spondylosis
What would spasmodic pain, numbness, a sensation of heaviness or a 'pins and needles' sensation in the arm associated with exercise suggest?
An attack of angina pectoris
What would a history of frequent falls with no loss of consciousness suggest?
A lesion in one of the areas of the brain dealing with balance and posture such as the cerebellum or basal ganglia eg Parkinson's disease or multiple sclerosis
What could the presence of a severe headache signify?
1. Migraine
2. Subarachnoid haemorrhage
3. Tumour
What is smoking a risk factor for?
Atherosclerosis and therefore CVAs
What problems can chronic alcoholism cause?
1. Motor coordination
2. Memory (Korsakoff's psychosis) - alcohol induced thiamine deficiency which damages the limbic system
What is progressive encephalopathy?
It is a an altered mental state which can be caused by the HIV virus
Which gender is affected more by myasthenia gravis?
Females
Which gender is affected more by Duchenne's muscular dystrophy?
Males
What neurological conditions are all associated with the over-60s?
1. Shingles (herpes zoster)
2. Parkinsonism
3. CVAs
What is the most likely age of onset of shingles (herpes zoster)?
Over 60
What is the most likely age of onset of Parkinsonism?
Over 60
What is the most likely age of onset of CVAs?
Over 60
When is Charcot-Marie-Tooth likely to manifest itself?
When people are in their 20s
When is spina bifida likely to manifest itself?
From birth
How does spina bifida occulta affect the lower limb?
1. A cavoid type foot
2. Clawed toes
Which are the two areas of the brain that are concerned with maintaining consciousness?
1. The cerebral cortex
2. Reticular formation
What is syncope?
A simple faint
What is the term for a simple faint?
Syncope
What three conditions can cause syncope?
1. Benign causes - emotional shock causing vasovagal syncope
2. Autonomic neuropathy if the fainting episode is associated with a change to an upright posture
3. Serious causes such as haemorrhage or anaphylactic shock
What would cause a physiological tremor?
Maintenance of posture is accompanied by a tremor (10Hz). This may be exacerbated by anxiety, fatigue or thyrotoxicosis
What would cause tremor in an older person?
With age the normal physiological tremor slows to 6-7 Hz. As a result the tremor becomes more noticeable especially when undertaking a slow motion such as picking up a cup to drink from
What is resting tremor caused by?
Tremor that is present during rest (4-5Hz) is seen in parkinsonism
What is intention tremor caused by?
Tremor that increases as the individual tries to undertake a coordinated movement as seen with cerebellar dysfunction
What causes an essential tremor?
Postural tremor similar to a physiological tremor but of much greater amplitude, usually hereditary
What drug can cause tremors?
Tremor similar to an essential tremor may occur in 40% of patients treated with barbiturates
What is a transient ischaemic attack (TIA)?
They are a temporary interruption in the vascular supply to the brain
What is the age when people have TIAs?
60+
What are the main causes of TIAs and strokes?
Thrombosis resulting from atheromatous plaques in cerebral vessels cause 80% of TIAs and strokes. Haemorrhage cause the remainder
How long do TIAs last?
From 1 to 30 minutes and always less than 24 hours
What disorders accompany TIAs?
1. Disorders of speech (dysphasia)
2. Disorders of vision
3. Disorders of movement (dyskinesia)
4. Disorders in swallowing (dysphagia)
What is the prognosis for a TIA?
A full recovery is usual
What is a disorder of speech called?
Dysphasia
What is a disorder of movement called?
Dyskinesia
What is a disorder of swallowing called?
Dysphagia
What is dysphasia?
A disorder of speech
What is dyskinesia?
A disorder of movement
What is dysphagia?
A disorder of swallowing
What is a petit mal?
A brief loss of consciousness during an epileptic fit
What is a brief loss of consciousness during an epileptic fit called?
Petit mal
What is a grand mal?
A loss of conscious accompanied by tonic-clonic jerks during an epileptic fit
What is a loss of conscious accompanied by tonic-clonic jerks during an epileptic fit?
A grand mal
How would a patient show they were alert and wakeful?
They would be fully aware of the environment and self and responds to stimuli
How would you classify a patient as confused?
The patient shows lack of attentiveness, cannot concentrate and has impaired memory
How would you classify a patient as delirious?
The patient would be anxious, excited, agitated and may be hallucinating
How would you classify a patient as lethargic?
The patient is drowsy but responds to verbal stimuli
How would you classifiy a patient in a stupor?
The patient is unconscious but responds to pain
How would you classify a patient in a coma?
Patient cannot be roused
What are the hospital tests that may be undertaken if a patient shows an altered level of consciousness?
1. Occuloplethysmography
2. Duplex Doppler ultrasound
3. Angiography
4. Brain scans
5. Electroencephalogram (EEG)
6. Lumbar punctures
7. Myelography
What is occuloplethysmography?
A non-invasive test to detect carotid lesions that cause a reduction in blood flow to the ipsilateral orbit compared to the opposite eye
What may a Duplex Doppler ultrasound reveal in vascular testing?
It may reveal a stenosis or occlusion of the carotid arteries and is often used prior to an angiogram
What is angiography used for in neurological disorders?
Injection of a radio-opaque dye into the suspected artery will show atherosclerotic plaques in cerebral vessels
What are brain scans?
They are computed tomography (CT) or MRI which can be used to confirm TIAs, full blown CVAs, neoplastic masses or epileptic foci
What does an EEG do?
It measures brain waves and are normally used to confirm a clinical diagnosis and locate the focus of epilepsy
What is a lumbar puncture?
A hollow needle is inserted into the spinal canal through the intervertebral space between L3 and L4 or L4-5 to withdraw cerebrospinal fluid
What does a lumbar puncture help diagnose?
1. Encephalitis
2. Meningitis
3. Guillain-Barre syndrome
4. Abscess
5. Tumour
6. Haemorrhage
What is myelography?
A radio-opaque dye is introduced into the subarachnoid space via a lumbar puncture and the fluid is manoeuvred to the suspected area
What does myelography help diagnose?
1. Tumours of the spinal cord
2. Diseases of the invertebral disc space
3. Bony abnormalities
4. Spondylitic lesions of the vertebral column
What are the sensory units that can be damaged and cause sensory deficits?
1. Parietal cortex
2. Ascending pathways
3. Receptors
What are the causes of sensory deficits?
1. Diabetes mellitus
2. Subacute combined degeneration of the spinal cord (vitamin B12 deficiency)
3. Congenital absence of particular sensory neuones
4. Spina bifida
5. Syringomyelia
6. Tabes dorsalis
7. Nerve injuries
8. Guillain-Barre syndrome
9, Multiple sclerosis
10. Cord compression/lesion eg tumour (Brown-Sequard syndrome)
11. Chronic alcoholism
What is Brown Sequard syndrome?
Damage to one side of the spinal cord results in ipsilateral loss of touch, position sense, two-point discrimination and vibration sense below the level of the lesion due to dorsal column injury and contralateral loss of pain and temperature sensation below the level of the lesion due to damage to the anterolateral tracts
What is neuropraxia?
Mild trauma or compression causing local demyelination and leading to temporary loss of function. Full recovery within days or weeks
What is axonotmesis?
Crush injuries causing degeneration of axon and myelin sheath (wallerian degeneration). Neurolemma sheaths intact and reinnervated
What is neurotmesis?
It is where a whole nerve axon is severed. Surgical repair is needed to ensure reinnervation of distal trunk
What is it where a whole nerve axon is severed and surgical repair is needed to ensure reinnervation of distal trunk
Neurotmesis
What is the term for the type of nerve damage where there is mild trauma or compression of a nerve caused by local demyelination and leading to temporary loss of function wth full recovery within days or weeks?
Neuropraxia
What is it called when a crush injury to a nerve causes degeneration of the axon and myelin sheath (wallerian degeneration) but the neurolemma sheathss are intact and reinnervated?
Axonotmesis
Where can referred pain be felt if there is damage to S1?
In the heel
If there is referred pain in the heel which is the likely nerve root to be affected?
S1
What can be used to test light touch?
Cotton wool/brush/monofilament
What is a monofilament used to test?
Light touch
What is the fibre type and pathway for light touch?
A-beta fibres and ipsilateral dorsal column
What can be used to test two point discrimination?
Dividers or two orange sticks
What would dividers or two orange sticks test?
Two point discrimination
What fibre type and what pathway in the spinal cord is two point discrimination?
A-beta fibres and ipsilateral dorsal column
What would be used to test vibration?
Tuning fork or neurothesiometer
What does the tuning fork or neurothesiometer test?
Vibration
What fibre type and what pathway in the spinal cord is vibration?
A-beta fibres and ipsilateral dorsal column
What would be used to test temperature?
Warm and cold test tubes
What would warm and cold test tubes test?
Temperature
What fibres and what pathway in the spinal cord is temperature?
A-delta and C fibres and contralateral (anterolateral columns)
With what would you test sharp pain/pinprick?
A neurotip
What would neurotips test?
Sharp pain/pinprick
What fibre type and what pathway in the spinal cord is sharp pain/pinprick?
A-delta and C fibres and contralateral anterolateral columns
What would test proprioception?
Dorsi/plantarflexion of the hallux
What does dorsi/plantarflexion of the hallux test?
Proprioception
What fibre type and pathway in the spinal cord is proprioception?
A-alpha fibres and ipsilateral dorsal columns
What do neurological tests test?
Neurological tests examine the integrity of the afferent pathways that involve the ipsilateral dorsal columns and the contralateral anterolateral columns
What non-pathological factors may cause neurological deficits?
Overlying callus and normal slowing of conduction rates associated with aging
What can be used to test light touch?
Cotton wool, a fine brush or a 10g monofilament
Are A-beta fibres large or small diameter
A-beta fibres are large diameter
What receptors are responsive to light touch?
Meissner's corpuscles
What are Meissner's corpuscles?
Receptors for light touch
Where are Meissner's corpuscles found?
They lie in the superficial dermis
What is used to test pressure?
The 10g monofilament
What was the first monofilament used for detecting neuropathy?
The Semmes-Weinstein monofilament
Who produced the Semmes Weinstein monofilament?
The Hansen's Disease Center, USA
How does a 10g monofilament work?
It buckles when a force of 10g is applied
What does inability to detect the 10g monofilament indicate?
It indicates neuropathy of large fibres
What can be used to test vibration?
The 128Hz tuning fork or a graduated Rydel-Seiffer tuning fork
What receptors are sensitive to pressure?
The pacinian corpuscles
Where are the pacinian corpuscles located?
Deep in the dermis
What are pacinian corpuscles?
The are receptors sensitive to pressure
Are A-delta fibres large diameter or narrow diameter?
They are narrow diameter
Are C fibres large diameter or narrow diameter?
They are narrow diameter
Which are the large diameter fibres?
A-beta fibres
Which are the narrow diameter fibres?
A-delta fibres and C fibres
What is Tinel's sign used for?
This helps in the diagnosis of nerve compression.
What can Tinel's sign be used for?
Tinel's sign can be used to assess for compression of the posterior tibial nerve (tarsal tunnel syndromes)
What is a sign of a suspected entrapment of the sciatic nerve?
When the affected leg is raised while the patient lies in a supine position
What hospital tests are used to test sensory function?
Nerve conduction tests and nerve biopsy tests
What is a nerve conduction test?
Sensory nerve conduction velocities are measured by placing stimulating electrodes on the skin over the nerve to be tested.
What four causes can cause slowing of conduction velocity in a nerve?
1. Ageing
2. Damage to the cell body as in herpes zoster or shingles
3. Nerve axon damage as in compression due to a spinal tumour, a slipped disc or tarsal tunnel syndrome
4. Demyelinisation as seen in Guillain-Barre syndrome
What is a nerve biopsy?
This can be carried out on sensory, motor and autonomic nerves. A small sample of tissue is removed and examined.
What are the signs that a motor system is functioning normally?
Muscles should display
1. resting tone
2. good muscle power on active contraction
3. be able to move against resistance
What are the graded reflex responses?
3+ = clonus
2+ = increased
1+ = normal
+/- = obtainable with reinforcement
0 = absent
What graded reflex response would suggest an UMN lesion?
Values of 2 or above
What would a value of 2 or above in the graded reflex response suggest?
There was an UMN lesion
What graded reflex response would suggest an LMN lesion, peripheral sensory nerve or muscle damage?
A value of below 1
What would a value of below 1 in the graded reflex response suggest?
It would suggest an LMN lesion, peripheral sensory nerve or muscle damage
What does the patellar reflex test?
It tests the integrity of the spinal reflex pathway L3 and L4 and demonstrates descending influences on the ventral horn
What would you do to relax the leg in preparation for a patellar reflex test?
The patient should clasp both hands around the other knee and pull.
What is a Jedrassik manoeuvre?
It is when the patient clasps both hands around the other knee and pulls.
How does the Jedrassik manoeuvre relax the leg?
It releases spinal influence.
What does the Achilles reflex test?
It tests the spinal pathway S1 and S2
What can cause lower limb motor dysfunction?
1. Damage to upper motor neurones
2. Damage to lower motor neurones
3. Damage to peripheral nerves or muscles
Where can upper motor neurone lesions occur?
Anywhere between the cortex and L1 in the spinal cord
Where does the spinal cord end?
L1
What does damage to the multineuronal pathway cause?
It causes release of inhibition on the LMNs in the spinal cord, especially those which innervate the antigravity muscles producing the effect most commonly associated with UMN lesions, that of spasticity or stiffness in the limbs
What is the effect most commonly associated with UMN lesions?
Spasticity or stiffness in the limbs
How does a UMN lesion affect the gait?
The effect is extension at the hip and knee with plantarflexion and inversion of the foot
If a UMN lesion is unilateral what is the term used to describe the person?
Hemiplegic
What is hemiplegia?
It is where a UMN lesion is unilateral.
If a UMN lesion affects both sides what is the term used to describe the person?
Paraplegic
What is paraplegia?
It is where a UMN lesion affects both sides
What are the ten conditions associated with UMN signs?
1. Cerebral palsy due to anoxia at birth
2. Cerebral vascular accidents
3. Brain injury
4. Friedrich's ataxia
5. Spinal injury
6. Brain or spinal tumours
7. Amyotrophic lateral sclerosis (motor neurone disease)
8. Vitamin B12 deficiency
9. Multiple sclerosis
10. Later stages of syringomyelia
What are the signs of an UMN lesion?
1. Exaggerated tendon reflexes
2. Extensor plantar response (+ve Babinski sign)
3. Loss of abdominal reflex
4. Normal electrical excitability of muscle
5. Some muscle wasting over a period of time due to lack of use
6. Increase in muscle tone (clonus)
7. Whole limb affected
What is increased muscle tone called?
Clonus
What is clonus?
Increased muscle tone
What causes clasp knife spasticity in UMN lesions?
It is due to a length dependent inhibition of the stretch reflext
What causes brisk tendon reflexes in UMN lesions?
Due to the reduced inhibition by the multineuronal tracts the alpha LMNs responsible for the contraction of extrafusal fibres are hyperexcited which results in exaggerated patella and ankle tendon reflexes
What causes a Babinski sign?
It is due to the release of a spinal inhibitory reflex
What causes increased muscle tone in UMN lesions?
Due to the release of spinal inhibition in UMN conditions, the LMNs will be in a hyperexcited state and so will be firing more frequently which leads to greater muscle tone and the affected muscle will feel very firm and tense
Which side of the body will be affected if UMN lesion is in the cortex?
The effects will occur on the contralateral side
If the UMN lesion is in the spinal cord where will the effects be?
The effects will be ipsilateral below the level of the lesion
What is paresis?
Weakness
What is the medical term for weakness?
Paresis
What is the medical term for complete loss of function?
Paralysis
What is paralysis?
Complete loss of function
What are diseases affecting the muscles?
Myopathies
What are myopathies?
Disease affecting the muscles
What are the four classifications of myopathies?
1. Inherited
2. Biochemical defect
3. Acquired inflammatory
4. Non-inflammatory
What are some of the inherited myopathies?
1. Muscular dystrophies
- Duchenne's
- Becker's
- Dystrophia myotonica
2. Facio-scapulo-humeral autosomal dominant condition
3. Limb girdle
What are some of the biochemical defects that can cause myopathies?
1. McArdle's syndrome
2. Malignant hyperpyrexia
What are acquired inflammatory conditions that can cause myopathies?
1. Polymyositis-autoimmune disease
2. Dermatomyositis
What are non-inflammatory conditions that can cause myopathies?
Secondary to high-dose steroids and thyrotoxicosis
What are the symptoms of Duchennes muscular dystrophy?
1. Commonest and most serious of the inherited dystrophies
2. Affects males
3. Onset before 10 years
4. Weakness in proximal and girdle muscles of lower limb first, later upper limbs
5. Hypertrophy and later fatty infiltration of calf muscles
6. Cardiac muscles also affected
7. Elevated levels of serum phosphokinase
8. Death from respiratory failure usually between 20 and 30 years
What are the symptoms of dystrophia myotonica?
1. Insidious onset, usually between 20 and 50 years but can be present earlier
2. Progressive weakening and wasting of distal as well as proximal limb muscles, facial and sternomastoids
3. Cardiomyopathy, cataracts and frontal baldness also common
4. Patient cannot open hand quickly after making a fist
5. Membrane hyperexcitability
What is myotonia?
Failure of muscle to relax immediately after contraction
What is the term used when there is a failure of the muscle to relax immediately after contraction?
Myotonia
What is facio-scapulo-humeral-autosomal dominant condition?
1. Benign
2. Often asympomatic
3. Wasting and weakness of facial, scapular and humeral muscles
4. Patient has difficulty in whistling, heavy lifting
5. Scapula is in abnormal condition.
What is McArdle's syndrome?
1. Abnormality of glycogen metabolism due to deficiency of muscle phosphorylase
2. Patient suffers from fatigue, cramps and muscle spasm
What is malignant hyperpyrexia?
1. No muscle wastage or weakness
2. Symptoms occur during or immediately after administration of a general anaesthetic especially if halothane or suxemethonium
3. Prolonged muscle contraction leading to raised body temperature
4. Fatal in 50% of cases
What is polymyositis-autoimmune disease?
1. Infiltration of monocytes and muscle necrosis
2. Weakness of proximal limb, trunk and neck muscles
3. Patient has difficulty raising hands above head, getting up out of low chairs and bath.
4. May be associated pain on muscular exertion
What is dermatomyositis?
1. Infiltration of monocytes and muscle necrosis
2. Weakness of proximal limb, trunk and neck muscles
3. Patient has difficulty raising hands above head, getting up out of low chairs and bath.
4. May be associated pain on muscular exertion
5. Involvement of skin of face and hands with erythematous rash
Where can an LMN lesion be found?
1. Since LMNs or their spinal nerves exit at all segments of the spinal cord, LMN symptoms can be seen as a result of damage to any segment from C1 to S5
2. Due to the anatomy of the spinal cord any damage to the cord from L2 will only result in an LMN lesion
Where can the damage be if there is a combination of UMN and LMN symptoms?
C1 and L1
What are eight conditions associated with LMN lesions?
1. Poliomyelitis
2. Injury to lower motor neurone and/or peripheral nerve
3. Motor neurone disease
4. Syringomyelia
5. Vitamin B12 deficiency
6. Cord compression/lesion (Brown-Sequard syndrome)
7. Spina bifida
8. Charcot-Marie-Tooth disease
What are the sites of damage for an LMN lesion?
1. Lower motor neurone eg polio
2. Peripheral axon eg diabetes
3. Neuromuscular junction eg destruction of cholinergic receptors of the skeletal muscle as in myasthenia gravis
What is the site of neurological damage from the polio virus?
A lower motor neurone
What is the site of neurological damage from diabetes
Peripheral axon
What is the site of neurological damage from myasthenia gravis?
The neuromuscular junction
What would be the differential diagnosis for LMN lesions?
Myopathies
What does the anterior tibial muscle control?
Deceleration of dorsiflexion at the ankle in gait
What does damage to the tibialis anterior nerve cause?
It produces a characteristic slapping gait
What are essential to the health of a muscle?
Nerve impulses
What is denervation atrophy?
Where lack of nerve impulses to the muscle lead to atrophy
What is the term for muscular atrophy due to lack of nerve impulses?
Denervation atrophy
When a LMN lesion causes fasciculation, what causes the quivering?
A denervated muscle become highly sensitive to very small amounts of neurotransmitter (acetylcholine) possibly due to upregulation of receptors which results in a quivering of the muscle (fasciculation)
What is fasciculation?
Quivering of the muscle
What is the medical term for quivering of the muscle?
Fasciculation
What is the MRC grading for muscle power?
5 = normal power
4+ = submaximal movement against resistance
4 = moderate movement against resistance
4- = slight movement against resistance
3 = moves against gravity but not resistance
2 = moves with gravity eliminated
1 = flicker
0 = no movement
What would a reduction or absence of all lower limb reflexes suggest?
1. Polyradiculopathy
2. Cauda equina lesion
3. Peripheral polyneuropathy
4. Myopathy
What would a single reduced or absent reflex suggest?
1. Mononeuropathy
2. Radiculopathy
What are the two chief pathological processes that occur in peripheral nerve disease?
1. Axonal degeneration
2. Segmental demyelination
What are diseases associated with axonal degeneration?
1. Polyneuropathies of diabetes
2. Alcoholism
3. Toxicity due to heavy metals
4. Nerve entrapment
5. Friedrich's ataxia
What are the symptoms of axonal degeneration?
1. Weakness, numbness and atrophy
2. Slowing of nerve conduction velocities and loss of large fibres
3. Reduction in action potential amplitude
4. More prominent distally than proximally (longest fibres affected first)
5. fibrillation (fasciculations) seen on electromyograph
What are pathologies associated with segmental demyelination?
1. Vasculitis of RA
2. Guillain Barre syndrome
3. Charcot-Marie-Tooth/peroneal muscular atrophy/hereditary motor and sensory neuropathy
What are the symptoms of axonal degeneration?
1. Electrophysiological changes seen first
2. Dramatic fall in nerve conduction velocities, maybe even total conduction block
3. Worsens proximally
Is Charcot-Marie-Tooth disease an example of axonal degeneration or segmental myelination?
There are two subtypes. One shows segmental demyelination and the other shows axonal degeneration
What is electromyography?
A needle electrode is inserted into the muscle to show the electrical activity of the muscle.
What can electromyographies detect?
Dysfunction of motor nerves, neuromuscular junction lesions and myopathies
What is electromyography used for specifically?
It is the only means of testing for myopathies
1. If due to motor denervation such as polio
2. If due to changes at the neuromuscular junction such as myasthenia gravis
3. If due to muscle disease such as Duchennes muscular dystrophy
What are the symptoms of lower motor neurone lesions?
1. Loss of tendon reflexes
2. Flexor plantar response (-ve Babinski sign)
3. Normal abdominal reflex
4. Fasciculation (fibrillation seen on EMG)
5. Marked muscle wasting occurs relatively quickly
6. Flaccid muscles (lack of tone)
7. Certain muscle groups affected depending on site of damage
8. Deformity due to contracture of antagonists
What conditions that affect the cerebellum would cause poor coordination?
1. Tumour
2. Multiple sclerosis
3. Arnold-Chiari malformation
4. Friedrich's ataxia
5. Other hereditary spinocerebellar ataxias
6. Hypothyroidism
7. Repeated head trauma as in boxing
What conditions that affect the basal ganglia would cause poor coordination?
1. Parkinsonism
2. Huntington's chorea
3. Wilson's disease
4. Sydenham's chorea
What conditions that affect the ascending pathways would cause poor coordination?
1. Subacute combined degeneration of the spinal cord
2. Guillain Barre syndrome
3. Tabes dorsalis
4. Alcoholism
What can a stamping gait be symptomatic of?
It may be due to loss of proprioception due to tabes dorsalis where the ascending columns degenerate. The patient is unaware of where his body is in space and lifts his legs much higher than necessary to clear the ground. The patient will be unaware of when his foot is about to make ground contact and stamps his foot down. This stimulates pressure receptors proximally as vibrations travel from the foot travel up the leg and provide much needed information to the brain
What causes tabes dorsalis to get worse?
The ascending tracts in the dorsal columns degenerate
What are indications that proprioception is lacking?
The patient will not know where his body is in space and lifts his legs much higher than necessary to clear the ground. The patient will also be unaware of when his foot is about to make ground contact and so stamps the foot down. This stimulates pressure receptors proximally as vibrations from the foot travel up the leg and so provide much needed information to the brain.
What is the problem with a high stepping gait following by stamping?
Lack of proprioception
What is dysarthria?
Inability to speak or form syllables
What is the term for inability to speak or form syllables?
Dysarthria
What causes dysarthria?
Cerebellar dysfunction affects the speech muscles and produces a scanning speech with inappropriate syllabic stress and volume
What is most likely to be affected if the speech is scanning with inappropriate syllabic stress and volume?
The cerebellum
What is dysdiachokinesia?
This is where actions are no longer smooth, continuous movements but are broken down into their component parts producing clumsy jerky actions
What is it when actions are no longer smooth, continuous movements but are broken down into their component parts producing clumsy jerky actions?
Dysdiachokinesia
What is an intention tremor?
It is where the tremor increases in amplitude as the person tries to carry out any tasks with the affected limb. The tremor disappears at rest.
What is it when a tremor increases in amplitude as the person tries to carry out any tasks with the affected limb. The tremor disappears at rest?
An intention tremor
What dysfunction is an intention tremor associated with?
It is a cerebellar defect
What causes an intention tremor?
Dysfunction of the stretch reflex
What is an ataxic gait?
The gait will be clumsy or staggering
What is the term used to describe a clumsy or staggering gait?
An ataxic gait
What does damage to the basal ganglia cause?
It produces either a poverty of movement (hypo/bradykinesia) of jerky, writhing movements (choreoathetosis)
What is hypokinesia?
Poverty of movement
What is bradykinesia?
Poverty of movement
What are the terms used to describe poverty of movement?
Hypokinesia or bradykinesia
What is choreoathetosis?
Jerky writhing movements
What are jerky writhing movements called?
Choreoathetosis
What pathologies are associated with hypo/bradykinesia?
Parkinson's disease
What pathologies are associated with choreoathetosis?
Huntington's chorea or Sydenham's chorea
What pathology is Sydenham's chorea associated with?
Rheumatic fever
Which pathology is associated with long-lasting choreoathetosis and which pathology is associated with a brief benign effect of choreoathetosis?
Huntingdon's chorea is associated with long-lasting choreoathetosis and Sydenham's chorea is associated with a brief benign bout of choreoathetosis
What does Romberg's sign detect?
It can be used to confirm proprioceptive disturbance in the dorsal columns or peripheral nerves
How is Romber's test carried out?
The patient is observed standing with feet together, eyes open and then closed.
What is the problem if a patient is unable to maintain balance if the eyes are open during Romberg's test?
It could be a cerebellar or vestibular defect and if the patient rocks backward and forward with eyes open a cerebellar defect could be the cause. If the eyes are open this is not a +ve Romberg's sign and cannot be performed
What does a positive Romberg's sign indicate?
1. Cord compression
2. Tabes dorsalis
3. Vitamin B12 deficiency
4. Degenerative spinal cord disease
What is nystagmus?
Rapid eye movements
What causes nystagmus?
Vestibular dysfunction
What can elicit nystagmus?
A rapid head movement
What does the presence of nystagmus show?
Its presence indicates a cerebellar lesion
What tests are used to test cerebellar dysfunction?
1. Romberg's
2. Heel-shin test
3. Heel-toe test
4. Finger-nose test
What other symptoms could be caused by a patient staggering around the midline when asked to perform the heel-toe test?
Old age or alcohol
What is the muscle tone like in cerebellar dysfunction?
It will be reduced in the affected limbs
What are tendon reflexes like in cerebellar dysfunction?
Tendon reflexes may be unusually sustained because of the oscillations of an abnormal stretch reflex but they should not be exaggerated
What is the most common extrapyramidal disease?
Parkinson's disease
What is hypermetria?
Over-reaching the intended object
What is the medical term for over-reaching an intended object?
Hypermetria
What is hypometria?
Underreaching an intended object
What is the medical term for underreaching an intended object?
Hypometria
What causes Parkinson's disease?
Parkinson's disease is due to a depletion of dopaminergic neurones in the substantia nigra which project to the caudate nucleus
What are the symptoms of Parkinson's disease?
1. Hypo/bradykinesia which results in the patient having great difficulty initiating or stopping movement
2. Rest tremor. If the hand is affected the tremor may cause the patient to move index finger and thumb in a 'pill-rolling' movement
3. Rigidity
4. The patient may show a mask-like face and speak in a soft voice
5. Small handwriting (micrographia) is also a characteristic
6. The antigravity muscles are affected producing a stooped posture with knees flexed so the patient's centre of gravity is no longer over the base of gait. This causes the patient to move more and more quickly to avoid falling forward
7. Gait also tends to be shuffling with poor heel-ground contact - 'marche a petit pas'
8. Tendon reflexes are unaffected
9. There is a general resistance to passive stretch described as lead pipe rigidity. It may show a superimposed intermittent release of the resistance, producing a series of jerks (the cogwheel effect)
10. There is no habituation with the glabellar tap reflex
What is micrographia?
Small handwriting
What is the medical term used for small handwriting?
Micrographia
What is the shuffling of Parkinson's disease called?
Marche a petits pas
What is marche a petits pas?
The shuffling of Parkinson's disease
What is the glabellar tap reflex?
A practitioner gently, slowly and repeatedly taps the forehead of the patient between the eyes. In a healthy person the first tap or two will elicity the eye-blink reflex but this will rapidly habituate
What do the autonomic nerves do?
They innervate the viscera and internal structures such as blood vessels and enable the nervous system to maintain homeostais
What are two of the signs which would suggest autonomic neuropathy?
1. Abnormal sudomotor responses in the skin
2. Abnormal cardiovascular responses in the functioning of the heart and peripheral blood vessels
What does sudomotor neuropathy lead to?
Absence of sweating and a dry skin although it may produce hyperhidrosis
What does the absence of sweating and a dry skin or hyperhidrosis indicate?
Sudomotor neuropathy
What does vasomotor neuropathy cause?
It usually produces a warm red skin and an absence of vasoconstriction in response to cold although it may produce a prolonged vasoconstriction. It may also lead to postural hypotension
What is postural hypotension?
It is loss of blood pressure when rising after lying or sitting down
What does neuropathy of nerves of cardiac pacemaker tissue lead to?
The heart fails to respond appropriately to the demands of the body eg an absence of tachycardia in response to exercise
What tests can measure autonomic function?
1. Heart rate supine and standing
2. Blood pressure supine and standing
3. Valsalve manoeuvre
How many beats per second should a heart rate increase by in a healthy person between a supine position and an upright position?
The heart beat should increase by more than 11 beats per minute
If the heart rate does not increase by more than 11 beats per minute what would this suggest?
Parasympathetic abnormality
What should happen in a healthy person when blood pressure is taken supine and standing?
Systolic blood pressure should fall on standing by approximately 30mmHg and the diastolic pressure should fall by 15mmHg
What does it indicate when the systolic pressure doesn't drop by 30 mmHg on standing and diastolic pressure by 15mmHg on standing?
It suggests a sympathetic abnormality
What could happen if the cardiovascular system cannot compensate for postural effects?
Postural syncope
What is the Valsalva manoeuvre?
The patient is asked to take a deep breath and exhale against a closed glottis (or blowing up a balloon) for 10-15 seconds and then breathe normally. The pulse rate is taken during the Valsalva manoeuvre and on release. Heart rate should increase during manoeuvre and fall on release. No increase during the manoeuvre suggests sympathetic abnormality and no decrease on release suggests sympathetic abnormality
When should you not do the Valsalva manoeuvre?
If there is evidence of proliferative retinopathy
What should happen to a healthy person during the Valsalve manoeuvre?
Heart rate should increase during the manoeuvre and fall on release
What does it indicate if there is no increase in heart rate during the Valsalva manoeuvre?
It suggests sympathetic abnormality
What does it indicate if there is no decrease on release during the Valsalve manoeuvre?
It suggests parasympathetic abnormality
What is the Valsalva manoeuvre testing?
Abnormal responses to the baroreceptor reflex which implicates defects in innervation of the cardiac pacemaker tissue rather than peripheral autonomic neuropathy
What are the tests for peripheral autonomic neuropathy?
There are no clinical tests
What are the signs of peripheral autonomic sympathetic neuropathy?
1. A dry skn due to failure of sudomotor nerves
2. A warm foot due to lack of arterial vasoconstriction
3. Engorged dorsal veins due to lack of venous vasoconstriction
What are signs of parasympathetic neuropathy?
Disorders of bowel and bladder function and impotence
What is the most common condition associated with autonomic neuropathy?
Diabetes mellitus
What other conditions besides diabetes mellitus are associated with autonomic neuropathy?
1. Guillain Barre syndrome
2. Amyloidosis
3. Congenital autonomic failure
What is amyloidosis?
amyloidosis refers to a variety of conditions in which amyloid proteins are abnormally deposited in organs and/or tissues.
What other conditions can affect the cardiovascular system and may give a false/positive result when testing for autonomic neuropathy?
1. Infection
2. Anaemia
3. Beta blockers
What parts of the nervous system are affected by diabetes mellitus?
1. Sensory
2. Motor (LMN)
3. Autonomic
What parts of the nervous system are affected by motor neurone disease?
1. LMN
2. UMN
What parts of the nervous system are affected by spina bifida?
1. LMN and sensory
What parts of the nervous system are affected by syringomyelia?
1. Sensory
2. LMN
3. UMN
What is syringomyelia?
Syringomyelia is a generic term referring to a disorder in which a cyst or cavity forms within the spinal cord. This cyst, called a syrinx, can expand and elongate over time, destroying the spinal cord
What part of the nervous system does Vitamin B12 deficiency affect?
1. Sensory
2. LMN
3. UMN
What part of the nervous system does multiple sclerosis affect?
1. Sensory
2. UMN
What part of the nervous system does cord compression/lesion affect?
1. Sensory
2. LMN
3. UMN
What part of the nervous system does Guillain-Barre syndrome affect?
1. Sensory
2. Autonomic
3. LMN
What part of the nervous system does Charcot-Marie-Tooth disease affect?
Mainly LMN but possible sensory
What part of the nervous system do nerve injuries affect?
Depends upon site, may result in LMN, UMN, sensory or autonomic
If a patient exhibits apraxic gait, aphasia, speech defects and visual defects where would the site of the lesion be and what could the possible disease be?
1. UMN (hemisphere
2. Stroke
3. Hydrocephalus
4. Head injury
If a patient exhibited progressive focal deficit epilepsy where would the site of the lesion be and what could the possible disease be?
1. UMN (head)
2. Tumour
3. Ischaemic stroke
4. Previous intracranial disease
If a patient exhibited increased tone and reflexes, weak arm extensors and weak leg flexors where would the site of the lesion be and what could the possible disease be?
1. UMN (head/spinal cord)
2. Neck, cervical region
3. Stroke
4. Cerebral palsy
5. Neck injury
6. Multiple sclerosis
If a patient exhibite hypo/bradykinesia, festinating gait, lead-pipe/cog-wheel rigidity, rest tremor where would the site of the lesion be and what would the cause be?
1. Basal ganglia
2. Parkinson's disease
If a patient exhibited choreoathetotic movements where would the site of the lesion be and what would the cause be?
1. Basal ganglia
2. Huntington's chorea
3. Sydenham's chorea (rare)
If the patient exhibited nystagmus, dysarthria and cranial nerve palsies where would the site of the lesion be and what would the cause be?
1. Brain stem
2. Multiple sclerosis
3. Syringomyelia
If the patient exhibited nystagmus, dysarthria, scanning speech, diminished pendular reflexes, intention tremor, ataxic gait, dysdiadochokinesia where would the site of the lesion be and what would the cause be?
1. Cerebellum
2. Spinal cord
3. Friedrich's ataxia
4. Stroke
5. Tumour
6. Vitamin B12 deficiency
7. Syringomyelia
8. Spina bifida
If a patient exhibited diminished tendon reflexes, paresis/paralysis, pain, paraesthesia/anaesthesia where would the site of the lesion be and what would the cause be?
1. LMN (spinal cord/nerve roots/axons)
2. Poliomyelitis
2. Diabetes mellitus
3. Chronic alcoholism
4. Guillain-barre syndrome
5. Rheumatoid arthritis
6. Charcot-Marie-Tooth disease
7. Vitamin deficiencies (B1, B6, B12)
8. Tumour
9. Disc protrusion
10. Trauma
If a patient exhibited progressive fatiguability and weakness where would the site of the lesion be and what would the cause be?
1. Neuromuscular junction
2. Myasthenia gravis
If a patient exhibited proximal limb muscle weakness and wasting but no sensory loss and no fasciculation where would the site of the lesion be and what would the cause be?
1. Muscle
2. Myopathies
How many cardinal planes are there and what are they?
1. Sagittal
2. Frontal (coronal)
3. Transverse
What do cardinal planes form the reference points for?
1. Position of a part of the body
2. Joint motion
3. Position of a joint
4. Deformity of a part of the body
What plane does anterior and posterior describe
Anterior and posterior describe positions in the frontal plane eg the patella lies anterior to the knee joint
What terms describe positions in the frontal plane?
Anterior and posterior
What terms describe positions in the transverse plane?
Distal and proximal
What cardinal planes does distal and proximal describe the positions of?
The transverse plane
What terms describe positions in the sagittal plane?
Lateral and medial
What cardinal plane does lateral and medial describe the positions of?
The sagittal plane
What are the motions in the sagittal plane?
Dorsiflexion and plantarflexion
What cardinal plane does dorsiflexion and plantarflexion describe the motions of?
The sagittal plane
What are the motions in the frontal (coronal plane)?
Inversion and eversion
What cardinal plane does inversion and eversion describe the motions of?
Frontal (coronal) plane
What are the motions in the transverse plane?
Abduction and adduction
What cardinal plane does adduction and abduction describe the motions of?
The transverse plane
Why is adductor hallucis so named?
Adductor hallucis is inserted into the lateral side of the proximal phalanx of the hallux and is so named because it brings about adduction of the hallux - movement of the hallux towards the midline of the foot
What is triplanar motion?
If a joint axis is positioned at an angle of less than 90 degrees to all the cardinal body planes triplanar motion occurs
What are examples of triplanar motion?
Pronation and supination
What movements make up pronation?
Dorsiflexion, abduction and eversion
What are the collective movements of dorsiflexion, abduction and eversion called?
Pronation
What movements make up supination?
Plantarflexion, adduction, inversion
What are the collective movements of plantarflexion, adduction and inversion called?
Supination
Where in the foot do triplanar motions occur?
The subtalar joint and midtarsal joints
What suffix is used to describe the position of a joint?
-ed eg a foot is dorsiflexed or plantarflexed
Why is it important that a distinction be made between joint motion and joint position?
Because a joint moves in the opposite direction to the position it is in eg at heel strike the foot is slightly supinated (position) but as soon as the heel contacts the ground pronation (motion) occurs at the subtalar joint in order to absorb shock from ground contact
What position is the foot at heel strike?
Supinated
What motion occurs as soon as the heel contacts the ground?
Pronation of the subtalar joint
Why does the subtalar joint pronate when the heel contacts the ground?
To absorb shock from ground contact
What is the definition of deformity?
It is used to describe a fixed position adopted by a part of the body
What suffix is used to denote deformity?
-us eg equinus when the foot or part of the foot is plantarflexed
What is equinus?
When the foot or part of the foot is plantarflexed eg ankle equinus
What is extensus?
When the foot or part of the foot is dorsiflexed eg hallux extensus
What is hallux extensus?
When the hallux is dorsiflexed
What is Calcaneus when it is being described as a fixed deformity?
It is rarely seen but it is used to describe the calcaneus when it is in fixed dorsiflexion eg talipes calcaneovalgus
What are the deformities in the sagittal plane?
Equinus and extensus
What plane are equinus and extensus in?
The sagittal plane
What are the deformities in the frontal plane?
Varus and valgus
What plane are varus and valgus in?
The frontal plane
What are the deformities in the transverse plane called?
Adductus or abductus
What plane are adductus or abductus in?
The transverse plane
What is genu valgum?
Knock knees
What is the medical term for knock knees?
Genu valgum
What is genu varum?
Bow leg
What is the medical term for bow leg?
Genu varum
What plane are genu varum and genu valgum in?
Frontal plane
What are two frontal plane deformities?
Genu varum and genu valgum
Describe genu varum?
The knees are far apart and the medial malleoli are close together
What is the medical term for when the knees are far apart and the medial malleoli are close together?
Genu varum
Describe genu valgum
The knees are close together and the medial malleoli are far apart
What is the medical term for when the knees are close together and the medial malleoli are far apart?
Genu valgum
What are the factors that can affect normal function?
1. Hereditary/congenital problems eg Charcot-Marie-Tooth disease, talipes equinovarus, CDH ???
2. Acute/chronic injury causing pain eg slipped femoral epiphysis, ankle sprain
3. Abnormal alignment secondary to trauma eg femoral/tibial/epiphyseal fracture
4. Abnormal alignment (developmental) eg internal femoral torsion, genu valgum
5. Infections eg tuberculosis
6. Neurological disorders eg CVA
7. Muscle disorders eg Duchenne's muscular dystrophy
8. Neoplasia eg osteosarcoma
9. Systemic disease eg autoimmune (RA), bone disease (Paget's disease)
10. Degenerative processes eg osteoarthritis
11. Joint hypermobility eg Marfan's syndrome
12. Osteochondroses eg Perthe's disease
13. Psychological factors eg attention seeking
14. Footwear eg high-heeled shoes
Describe what normal lower limb function should be?
Pain-free and energy efficient
What is the purpose of an orthopaedic lower limb assessment?
1. Establish the main complaint(s) eg pain, stiffness, tenderness, numbness, weakness or crepitus
2. Identify the site of the primary problem eg foot, leg, knee, hip and try to relate to underlying structures
3. Identify any secondary problems and relate them to the primary problem eg lesion patterns, pronation due to leg-length discrepancy
4. Identify the cause of the problem eg abnormal alignment
5. Establish how the problem evolved
6. Identify any movement/activity that produces/exacerbates symptoms
7. Identify movement/activity that relieves symptoms
8. Establish any differential diagnoses
9. Utilise the data from the assessment to produce an effective management plan
10. Utilise the data from the assessment to monitory the progress of the condition
When assessing the lower limb what is it important to observe?
Weightbearing (dynamic and static) and non-weightbearing
What can a forefoot varus cause?
Abnormal pronation of the subtalar joint
What could a bouncy gait be an indication of?
Early heel lift
What sort of gait can early heel lift cause?
A bouncy gait
What is a cause of ankle equinus?
A short gastrocnemius muscle
What can an early heel lift be an indication of?
A short gastrocnemius muscle
What factors must be assessed when gaining a full and detailed picture of the function of the locomotor system?
1. Gait
2. Alignment and position of the lower limb
3. Joint motion
4. Muscle action
What sequence should be adopted when assessing the locomotor system?
1. Gait analysis. This will focus on the position and alignment of the body and foot-ground contact
2. Non weight-bearing. This will focus on the assessment of joints and muscles
3. Static weightbearing. This will focus on the position and alignment of the body and the relationship of the foot to the ground during stance
What is compensation?
It is a change in structure, position or function of one part in an attempt to adjust to an abnormal structure, position or function in another part eg scoliosis of the spine may lead to an apparent leg-length discrepancy which will affect foot function
What may scoliosis of the spine lead to?
An apparent leg-length discrepancy which will affect foot function
What may an uncompensated rearfoot varus lead to?
Discomfort and pain at the knee
What is the process of musculoskeletal assessment?
1, General observation of the patient
2. Specific joint observation
3. Palpation
4. Examination of joint movement
5. Muscle assessment
6. Undertaking special tests
7. Arranging further investigation
What are clinical features associated with pathology of joints in the lower limb?
1. Oedema
2. Contusion
3. Erythema
4. Local muscle wasting
5. Alteration in shape or the presence of scars
6. Comparison of symmetry of contralateral parts
7. Abnormal posture
8. Evidence of limb shortening
9. Abnormal joint movement during gait
What clinical features may be evident from palpation of the limb segment?
1. Raised or lowered skin temperature
2. Swelling/effusion
3. Tenderness
4. Pain or abnormal lumps/nodules
What are features of an inflamed joint?
1. Redness
2. Heat
3. Pain
4. Swelling
5. Loss of function
What could inflammation of a joint be due to?
1. Trauma
2. Infection
3. Loose body (osteochondritis dissecans)
What is osteochondritis dissecans?
A loose body in the joint
What is the medical term for a loose body in the joint?
Osteochondritis dissecans
Before examining a joint what is it important to do?
Make sure the joint is warmed up (moved through its range of motion)
What does warming up the joint do?
It relaxes the ligaments and muscles and reduces the viscosity of the synovial fluid
What is ROM?
Range of motion
What is DOM?
Direction of motion
What is QOM?
Quality of motion
What is SOM?
Symmetry of motion
What is ROM measured in?
In degrees
What is the expected norm of ROM at the 1st MTPJ?
70 degrees
What is the condition caused where there is limited ROM at the 1st MTPJ?
Hallux limitus
What is hallux limitus?
Where is limited ROM at the 1st MTPJ
What instruments can be used to measure ROM?
Protractors, tractographs and goniometers
What is the normal total ROM of transverse plane rotation at the hip?
90 degrees
What is dislocation?
Dislocation occurs where there is no contact between articulating surfaces of the joint
What is the condition called where there is no contact between articulating surfaces of the joint?
Dislocation
What is subluxation?
Where there is only partial contact between articulating surfaces of the joint.
What is the condition called where there is only partial contact between articulating surfaces of the joint?
Subluxation
What is the test for articular damage in an MTPJ?
Compression of the metatarsal head against the proximal phalanx
What is the test for capsular damage in an MTPJ?
Dorsiflexion/plantarflexion of a distracted proximal phalanx against the joint capsule dorsally/plantarly (pulling the joint slightly apart)
What can cause joint stiffness?
Inflammatory or degenerative changes
What can cause tightness or tension in a joint?
Swelling or protective muscle spasm
What can cause popping in a joint?
A muscle tear or strain
What can cause snapping in a joint?
A tendon slipping over a bony prominence
What can cause clicking in a joint?
A meniscal tear or patella rubbing femoral condyles
What can cause grating in a joint?
Osteoarthritis or osteochondritis
What can cause crepitus in a tendon?
Inflammation of a tendon
What can cause crepitus in a joint?
Articular damage or a loose body
What can cause tearing in a joiont?
Muscle or ligament tear
What can cause tingling in a joint?
Neural or circulatory pathology
What can cause warmth in a joint?
Local inflammation or infection
What can cause numbness or hypersensitivity in a joint?
Local nerve or nerve root compression
What symptoms can inflammatory or degenerative changes cause in a joint?
Joint stiffness
What symptoms can swelling or protective muscle spasm cause in a joint?
Tightness or tension
What symptom can a muscle tear or strain cause in a joint?
Popping
What symptom can tendon slipping over a bony prominence cause in a joint?
Snapping
What symptom can a meniscal tear or patella rubbing femoral condyles cause in a joint?
Clicking
What symptom can osteoarthritis or osteochonditis cause in a joint?
Grating
What symptom can inflammation of a tendon cause?
Crepitus
What symptom can articular damage or a loose body cause in the joint?
Crepitus
What symptom can neural of circulatory pathology cause in a joint?
Tingling
What symptom can local inflammation or infection cause in a joint?
Warmth
What symptom can local nerve or nerve root compression cause in a joint?
Numbness or hypersensitivity
What should muscles be tested for?
1. Strength
2. Tone
3. Spasm
4. Bulk
What grading system is used for muscle strength?
The Medical Research Council (MRC) system
What is the MRC system for grading muscle strength?
0 = no contraction
1 = a flicker from muscle fasciculi
2 = slight movement with gravitational effect removed
3 = muscle can move part against gravity
4 = muscle can move part against gravity + resistance
5 = normal power
What is the term used when the patient moves the body part?
Active movement
What would an active ROM mean?
The patient was moving the joint in ROM
What is the term used when the practitioner moves the body part?
Passive movement
What would a passive ROM be?
When the practitioner moves the body part in ROM
Describe what muscle tone is?
That a muscle is in a state of partial contraction without full movement being necessary
What is a useful measure of muscle tone?
Asking the patient to undertake isometric contraction of a muscle eg the tone of the quadriceps can be assessed by asking the patient to contract the muscle while the knee is in an extended position
What should normal toned muscles feel like when contracting?
They should feel firm as well as appear taut
What do muscles look and feel like when they lack tone?
Flaccid
What could flaccid muscles be a sign of?
Lower motor neurone disorders
What could absence of tone in young males indicate?
Duchenne's muscular dystrophy
What can a spasm affect?
Joint motion
How many types of muscle spasm are there and what are they?
1. Tonic
2. Clonic
Why does a tonic spasm occur in a muscle?
It is usually an attempt by the muscles to stop movement at a painful joint
What is a clonic spasm and what is it associated with?
It is associated with neurological (upper motor neurone) deficit and is involuntary
What is atrophy of muscle and what can it be due to?
1. Lack of use
2. Lower motor neurone lesion
What causes hypertrophic muscles?
Exercise
What does Lachman's test assess?
It assesses sagittal plane stability of the knee in an anterior direction and the integrity of the anterior cruciate ligament
What does gait involve?
It involves complex neuromuscular coordination of the lumbar spine, pelvis, hips and those structures distal to them
What are three dysfunctions that can influence gait?
1. Neurological
2. Systemic
3. Structural
What are the neurological dysfunctions that can influence gait?
1. Motor eg CVA
2. Sensory eg tabes dorsalis, blindness
3. Cerebellum eg Friedrich's ataxia
4. Basal ganglia eg Parkinson's disease
What are the systemic dysfunctions that can influence gait?
1. Joint disease eg RA, OA
2. Crystal arthropathies eg gout
3. Muscle disease eg Duchennes muscular dystrophy, dermatomyositis
4. Bone disease eg rickets, Paget's disease
What are the structural dysfunctions that can influence gait?
1. Limb-length inequality eg DDH???, polio, femoral/tibial fracture
2. Alignment disorders eg coxa valga/vara, genu valgum/varum/recurvatum, tibial /femoral torsion, rearfoot varus
What is gait divided into?
Swing phase and stance phase
What happens in stance phase?
The period of the gait cycle when the foot is in contact with the ground
What does swing phase relate to?
Swing phase is when the foot is not in contact with the ground
What does stance phase consist of?
1. Contact
2. Midstance
3. Propulsive stages
When does contact phase start and end?
Contact phase starts when the heel makes ground contact and this is followed by the rest of the foot
What happens during contact phase?
The foot pronates in order to absorb shock from the effects of ground reaction
When does the foot pronate in order to absorb shock from the effects of ground reaction?
During contact phase
When does midstance start and finish?
Midstance starts when all the foot is in ground contact and ends with heel lift
What happens during midstance?
The foot starts to resupinate ready for propulsion
What part of stance does the foot start to resupinate ready for propulsion?
During midstance
When does propulsion start and finish?
Propulsion starts at heel lift and ends when the hallux leaves the ground
What happens during propulsion?
The foot continues to supinate
When part of stance does the foot continue to supinate?
During propulsion
During propulsion what part of the foot is the first to leave the ground and what part of the foot is the last to leave the ground?
The fifth metatarsal head is the first part of the foot to leave the ground and the hallux should be the last to leave the ground
What are the anatomical and functional features to observe during gait?
1. Head position
2. Shoulder position
3. Arm swing
4. Trunk position/rotation
5. Pelvic tilt
6. Limb motion
7. Thigh segment
8. Patellar position (transverse plane)
9. Knee position (frontal/sagittal plane)
10. Tibial position
11. Ankle
12. Calcaneal position
13. Navicular position
14. Midtarsal joint (position/movement)
15. Metatarsals (anterior/lateral views)
16. Toe position
17. Foot position/shape
18. Muscle activity
19. Propulsion
20. Swing phase
What is torticollis?
Torticollis is where the head is twisted to one side due to muscle contracture
What is the term used to describe where the head is twisted to one side due to muscle contracture?
Torticollis
Where will the head tilt due to cervical scoliosis?
The head will tilt down on the long limb side
What could unilateral tilting of the shoulders be due to?
Limb length inequality or scoliosis
Where will shoulders tilt in children under 12 years with leg length inequality?
The shoulder will always tilt to down on the short limb
Where will the shoulders tilt in adults with secondary scoliosis?
The shoulders will tilt on the long side
What does arm swing denote?
Arm swing is a feature of normal forward progression. The arms should swing to even out leg movement
What does a flexed position of arm or hand held close to the body suggest?
CVA
What is the arm position in patients with LLI?
The arm on the shorter side will be held away from the body to help maintain balance and will hang lower than the contralateral arm
What is spinal kyphosis?
It is curvature of the upper (thoracic) spine
What is curvature of the thoracic spine called?
Spinal kyphosis
What is spinal lordosis?
An abnormal inward curve of the lumbar spine
What is an abnormal curve of the lumbar spine called?
Spinal lordosis
What is the smooth up and down motion of the pelvis called?
Sinusoidal motion
What is sinusoidal motion?
The smooth up and down motion of the pelvis
What are four causes of pelvic tilt?
1. Neurological problems
2. Spinal deformity
3. LLI (pelvis tilts down on side of short limb)
4. Injury
What can weakness of the gluteus medius muscle cause?
Trendelenburg gait
What sort of gait does a CVA patient have?
Exaggerated circumducted movement
What would an exaggerated circumducted movement in gait indicate?
CVA
What is excessive transverse plane rotation in the thigh called?
Internal and external rotation
Is the normal leg internally or externally rotated at heel strike?
Internal rotation
If a normal leg is internally rotated where is the patella facing?
The patella should face inward
Is the normal leg internally or externally rotated during midstance and when propelling?
Externally rotated
If a normal leg is externally rotated where is the patella facing?
The patella is facing outward
Where does torque conversion take place in the leg?
The subtalar joint
What is internal rotation of the leg converted to in the foot?
Pronation
What is the function of pronation?
Shock absorption
What is external rotation of the leg converted to in the foot?
Supination
What is the function of supination?
It is required for stability of the foot during propulsion
What is excessive extension of the knee?
Genu recurvatum
What is genu recurvatum?
Excessive extension of the knee
What is valgum of the hip called?
Coxa
What can coxa valgum cause further down the leg?
Genu varum
What can coxa vara cause further down the leg?
Genu valgum
What could be indicated if a unilateral genu valgum or varum is present?
1. Injury
2. Infection
3. Growth disturbance at the epiphysis in earlier life
4. Tumour (rare)
What is bowing of the tibia in the frontal plane called?
Tibia varus
What is tibia varus?
Bowing of the tibia in the frontal plane
What further up the leg can cause rearfoot varus?
Tibial varus
What is sagittal plane tibial bowing called?
Sabre tibia
What is sabre tibia?
Sagittal plane bowing of the tibia
What pathology is sabre tibia an indication of?
Paget's disease
What is the minimum degrees of dorsiflexion in the ankle required for normal gait?
10 degrees
Why is dorsiflexion required in gait?
To allow the leg to pass over the foot during midstance
What plane do unstable ankles have instability in?
Frontal plane
What is another term for the ankle joint?
Talocrural joint
What is the talocrural joint?
The subtalar joint
What plane does the ankle joint move in?
Sagittal plane
What planes does the subtalar joint move in?
Frontal and transverse plane
What is an arthrodesis?
Where the joint is fused
What is the position of the calcaneus as it contacts the ground?
Slightly inverted
What happens to the calcaneus as a result of ground contact?
It everts
What three reasons could there be for an early heel lift?
1. Neurological problem
2. Ankle equinus
3. Hamstring tightness
What could rapid eversion of the calcaneus at heel contact be a compensation for?
A rearfoot deformity such as a fully compensated rearfoot varus
What is a fully compensated rearfoot varus sometimes called?
A heel strike pronator
What could a heel strike pronator be compensating for?
A fully compensated rearfoot varus
What happens to the navicular on pronation?
The talar head adducts
When the talar head adducts is the distance between the navicular and the ground reduced or increased?
Reduced
When the talar head adducts is the foot pronating or supinating?
Pronating
What happens to the navicular on supination
The talar head abducts
When the talar head abducts is the distance between the navicular and the ground reduced or increased?
Increased
When the talar head abducts is the foot pronating or supinating?
Supinating
When does the MTJ play its most important role?
During midstance and propulsion it maintains foot stability in order to withstand forces on the foot generated by uneven surfaces and during propulsion
What is an abductory twist?
Unlocking of the midtarsal joint during the last half of midstance if resupination fails to occur at the STJ. The MTJ unlocks and causes the forefoot to abduct on the rearfoot resulting in a less springy propulsive phase
What is the ideal number of degrees that the MTPJ should dorsiflex to for normal propulsion?
70 degrees
On ground contact are the toes dorsiflexed or plantarflexed?
Dorsiflexed
What muscles influence the position of the digits during the stance phase?
Lumbrical, interossei, long and short flexors and extensors
What is the role of the intrinsic muscles?
To provide transverse plane stability at the distal and proximal IPJs and prevent the toes from buckling under the effects of contraction of the extensors and/or flexors
What muscles provide transverse plane stability at the distal and proximal IPJs and prevent the toes from buckling under the effects of contraction of the extensors and/or flexors?
The intrinsic muscles
Why does clawing of toes occur?
When flexors have a mechanical advantage over the intrinsic and extensor muscles and when there is increased extensor muscle activity prior to heel lift
When flexors have a mechanical advantage over the intrinsic and extensor muscles and when there is increased extensor muscle activity prior to heel lift, what happens to the toes?
Clawing of the toes occur
What number of degrees abducted should a normal foot be in stance
About 13 degrees
Do cavoid feet have a high or low STJ axis?
A high STJ axis
Where and what are the likely problems caused by cavoid feet?
They produce a greater percentage of internal/external leg rotation which can result in proximal symptoms in the lower limb
Where and what are the likely problems caused by low-arched feet?
They produce increased frontal plane motion which causes symptoms in the feet
How does deceleration work?
The muscle resists joint movement by eccentric contraction
When the muscle resists joint movement by eccentric contraction, what is this called?
Deceleration
What are the extensor tendons of the foot doing on contact with the ground during gait?
They decelerate the foot
What does deceleration of the foot prevent?
Foot slap and allows the sole of the foot to contact the ground smoothly
What does paralysis of the anterior muscle group in leg cause?
It leads to a rapid collapse of the foot on the ground and an audible slap
What neuromuscular condition prevents the foot from clearing the ground during the swing phase?
Polio
What is the cause of an apropulsive gait?
When the hallux doesn't dorsiflex to 70 degrees and the hallux should be the last digit to leave the ground on propulsion
What are four causes of an apropulsive gait?
1. Hallux limitus/rigidus
2. Abnormal pronation
3. Unusual metatarsal formula
4. Excessive internal rotation of the leg
What are the three compensations for a lack of propulsion?
1. Rolling off its medial border
2. Propelling from a hyperextended (dorsiflexed) 1st IPJ rather than the MTPJ
3. Abductory twist
What can abnormal pronation be classified as?
Excessive pronation and/or pronation occurring when the foot should be supinating
What are five signs of abnormal pronation?
1. Excessive/prolonged internal rotation of the leg
2. Eversion of the calcaneus
3. Abduction at the midtarsal joint
4. Apropulsive gait
5. Abnormal phasic activity of the muscles
What is toe walking?
When there is no heel contact
When should heel lift occur?
It should normally occur at the end of midstance prior to propulsion
What can cause a bouncy gait?
Early heel lift
What sort of gait can an early heel lift cause?
A bouncy gait
What is the most common cause of an early heel lift?
Ankle equinus
What does a Trendelenburg gait look like?
It is characterised by a lurching/waddling gait where the pelvis tilts to the affected side
What is a waddling/lurching gait where the pelvis tilts to the affected side called?
Trendelenburg gait
What can cause a Trendelenburg gait?
Hip osteoarthritis due to weak gluteus medius muscles, congenital dysplasia of the hip or Achilles tendon lengthening procedure
What are four causes of a painful hip joint?
1. Osteoarthritis
2. Perthe's disease
3. Slipped capital femoral epiphysis
How is a painful hip joint held?
It is held in slight flexion, abduction and external rotation
What three conditions is a high knee lift produced during gait associated with?
1. Peroneal damage (Charcot-Marie-Tooth disease)
2. Weak tibialis anterior
3. Poliomyelitis
What is a circumducted gait?
The person will rotate the leg in an arc and flex the elbow and hand towards the body
What condition is associated with a circumducted gait?
CVA
What is a scissoring gait?
It is when legs cross the line of progression during gait
What condition is associated with a scissoring gait?
Cerebral palsy
What is a dystrophic/atrophic gait?
An exaggerated alternation of lateral trunk movements with an exaggerated elevation of the hip suggestive of the gait of a duck or penguin
What condition is associated with a dystrophic/atrophic gait?
Duchenne's muscular dystrophy
What is a festinating gait?
Small accelerating shuffling steps often taken on tip-toe
What condition is a festinating gait associated with?
Parkinson's disease
What is an ataxic gait?
An unstable poorly coordinated wide base of gait pattern
What condition is associated with an ataxic gait?
It is primarily seen in patients with cerebellar pathology
What is a helicopod gait?
The feet describe half circles as they shuffle along during contact and early mid-stance phase.
What condition is associated with a helicopod gait?
This gait is seen frequently in hysterical disorder
What 9 areas are examined during a non-weight-bearing examination?
1. Hip
2. Knee
3. Ankle
4. Subtalar
5. Midtarsals
6. Metatarsals
7. MTPJs
8. Digits (proximal and distal IPJs)
9. Alignment of the lower limb
What four structures make the hip stable?
1. Depth of the acetabulum
2. Strong capsule
3. Capsular ligaments
4. Surrounding muscles
How many planes does the hip move in?
Three
What is coxodynia?
Hip pain
If pain is felt on the outside of the femur where is this pain likely to originate from?
It is usually referred pain from the spine
Ideally how many degrees of flexion and extension should there be in the hip?
120-140 degrees of flexion and 5-20 degrees of extension
How do you assess hip flexion?
The patient is placed supine on a firm flat couch. The practitioner holds the leg firmly and flexes the hip by pushing the leg towards the body until resistance is met.
How do you assess hip extension?
The patient is placed in the prone position. The practitioner places one hand on the posterior superior iliac crest to stabilise the pelvis while the other hand holds the opposite knee just above the anterior knee and moves the leg towards the body to the point of resistance
What plane is flexion and extension in the hip joint?
Sagittal plane
What three conditions could cause loss of sagittal plane motion in the hip joint?
1. Pain
2. Femoral nerve entrapment
3. Effusion in the hip joint as the anterior ligaments iliofemoral and pubofemoral)will be under greater tension
What are the anterior ligaments in the hip?
Iliofemoral and pubofemoral
What are the sagittal plane movements of the hip?
Flexion and extension
What plane is abduction and adduction in the hip joint?
Frontal plane
What are the frontal plane movements of the hip?
Abduction and adduction
How do you assess abduction and adduction at the hip?
The patient lies supine and the practitioner holds the leg just below the anterior knee. The leg with the knee extended is moved across the opposite leg (adduction) and then brought back and abducted. The pelvis should be stabilised during this assessment by placing a hand on the opposite iliac crest
In a normal person what should there be less of in the hip joint, abduction or adduction?
There should be less adduction than abduction at the hip
What sort of gait can tightness of the abductors lead to?
A scissors type gait where one or both legs have a tendency to cross over during gait
What are the transverse plane movements at the hip?
Internal and external rotation
What plane is external and internal rotation of the hip in?
Transverse plane
What should the total range of transverse plane motion be in a normal adult and how is this divided between internal rotation and external rotation?
90 degrees, 45 degrees internal rotation and 45 degrees external rotation
What gender tends to show more internal rotation?
Females
How can you assess transverse plane motion at the hip?
The patient lies in a supine position. The hips and knees are flexed and the leg is moved medially and laterally as one would the arms of a clock
What could an internally rotated femur cause in the subtalar joint?
Abnormal pronation
What is the scouring/circumduction test?
This test is used to assess QOM and joint congruency in patients complaining of groin pain
What test is used to assess QOM and joint congruency in patients complaining of groin pain?
The scouring/circumduction test
How is the scouring/circumduction test performed?
The hip is flexed and adducted and the practitioner rotates the hip to test for any crepitations. If pain is provoked during this manoeuvre with the hip internally rotated a lesion of the acetabular labrum should be suspected
What is Patrick's or faber's test?
Flexion abduction external rotation (faber)
How do you do Patrick's or faber's test?
The patient lays supine with one leg straight. The other knee and hip are flexed so that the heel is placed on the knee of the straight leg. The knee is then slowly lowered into abduction. Gentle pressure is applied to the flexed knee while the opposite hand stabilises the pelvis over the opposite anterior superior iliac spine. This test stresses the medial hip capsule by placing an anteromedial force on the hip, the integrity of the iliofemoral/pubofemoral ligaments and also assesses for sacroiliac discomfort
What test assesses the medial hip capsule, the integrity of the iliofemoral/pubofemoral ligaments and assesses for sacroiliac discomfort?
Patrick's or faber's test
What does Patrick's or faber's test assess?
This test stresses the medial hip capsule by placing an anteromedial force on the hip, the integrity of the iliofemoral/pubofemoral ligaments and also assesses for sacroiliac discomfort
How do you do the sacroiliac joint provocation test?
The practitioner places her hands on the anterior superior iliac spines of the pelvis and presses down firmly and evenly to compress the joint and stress the sacroiliac ligaments. The test is positive if the patient experiences unilateral pain in the abdominal-groin, gluteal region or the leg
What condition also elicits pain in the hip joint area?
Pathology of the sacroiliac joint
If somebody has pathology of the sacroiliac joint where could they feel pain?
In the hip joint area
What happens if the test is positive for a sacroiliac joint provocation test?
The patient experiences unilateral pain in the abdominal-groin, gluteal region or the leg
How many hip muscle tests are there and what are they?
There are 9 and they are:
1. Young's test
2. Thomas's test
3. Ely's test
4. Ober's test
5. Piriformis test
6. Adductor strength test
7. Abductor strength test
8. Trendelenburg's test (stork test)
9. Laseque's (straight-leg raise) test
What fascia on the lateral side of the leg causes the knee and hip to flex when it is taut?
Tensor fascia latae
What action does a taut tensor fascia latae cause?
The knee and hip to flex
How do you perform Young's test?
By abucting the lower limb, tension on the tensor fascia latae is reduced and any flexion deformity should disappear
What is a possible cause of an apparent limb length discrepancy?
A tight tensor fascia latae
What can a tight tensor fascia latae cause?
An apparent leg length discrepancy
What does the iliopsoas group of muscles consist of?
1. Psoas minor
2. Psoas major
3. Iliacus
What is the function of the iliopsoas group of muscles?
They are prime flexors of the hip
What muscles are the prime flexors of the hip?
The iliopsoas group of muscles
What does Thomas's test do?
It rules out the presence of iliopsoas contracture
How do you perform Thomas's test?
The patient is supine. Bring both knees to the chest. Maintain pelvic tilt. Patient should lower the leg until it is relaxed or the pelvic tilt is lost. A positive finding is where there is lack of hip extension with knee flexion of 45 degrees or greater is positive
What group of muscles can irritate the femoral nerve?
The iliopsoas group
What nerve can tight iliopsoas muscles irritate?
The femoral nerve
What two problems can damage to the femoral nerve do in the upper leg?
1. Weakness of the quadriceps
2. Loss of sensation on the anterior and medial aspects of the leg
What nerve arises in the psoas major, crosses the hip joint and exits through the obturator foramen?
The obturator nerve
Describe where the obturator nerve goes
It rises in the psoas major and crosses the hip joint, exiting through the obturator foramen
What condition can injure the obturator nerve?
A slipped capita femoris epiphysis
What nerve can be injured due to a slipped capita femoris epiphysis?
The obturator nerve
What is a slipped capita femoris epiphysis?
Displacement of the head relative to the femoral
shaft common in boys aged 10-15. Primarily prevalent in overweight people and in persons with
Hispanic heritage
In Thomas's test what must the practitioner be looking for whilst performing this test?
While the patient flexes the hip, the practitioner must observe the opposite thigh for any sign of elevation. The lumbar spine must lie flat. If the iliapsoas muscles are tight, the contralateral hip will rise as the ipsilateral hip will force the lumbar spine against the couch.
What is Ely's test?
This test is used to assess hip flexor (rectus femoris) tightness or contracture.
What is a hip flexor?
Rectus femoris
What action does rectus femoris have?
Hip flexion
How do you perform Ely's test?
The patient lies prone and the knee is slowly flexed as far as possible until the heel comes close to the buttocks. Observe the buttock/hip during this manoeuvre. The point at which the buttock rises off the couch on the tested side indicates the degree of hip flexor tightness
What is Ober's test?
This test is designed to assess for iliotibial band contraction or tightness
How do you perform Ober's test?
The patient lies on his side with the inner knee flexed and the outer limb with the knee extended is moved anteriorly and adducted towards the couch. This stretches the lateral structures primarily the iliotibial band. A modified form of the test separately tests the short fibres of the knee which is achieved by flexing the knee and repeating the manoeuvre
What does a modified form of Ober's test by flexing the knee test?
The short fibres of the knee
What test could you use to test the short fibres of the knee?
A modified form of Ober's test by flexing the knee
What test assesses the tightness of the tensor fascia latae?
Young's test
What test assesses the tightness of the iliopsoas group of muscles?
Thomas's test
What test is used to assess hip flexor tightness?
Ely's test
What test is used to assess iliotibial band tightness?
Ober's test
What test is used to assess tightness of the piriformis?
The piriformis test
How do you perform piriformis test?
With the patient lying on his side, the hip and knee are flexed to 90 degrees. The examiner places one hand on the pelvis for stabilisation and with the other hand applies pressure at the knee pushing it towards the couch. This puts the piriformis muscle under tension. If tightness of the piriformis muscle is impinging on the sciatic nerve, pain may be produced in the buttock and also down the leg. Also in this position the strength of the external rotators of the hip can be tested by asking the patient to externally rotate the hip against resistance
Where do the adductors have their insertion?
On the medial side of the femur along the linea aspera
What part of the gait are adductor muscles important for and how do they work during swing phase?
They are important during the swing phase, stabilising the contralateral side of the hip against the pelvis as the leg swings forward
How can adductors be tested?
The patient lies supine with both both legs flexed at the hip and knee with the knees apart. The practitioner puts their hand on the medial side of the knee and asks the patient to push against the hand
What is the function of gracilis?
It is a partial adductor and rotates the femur on the hip
What are the group of adductor muscles?
adductor longus, adductor magnus, adductor brevis
are all adductors of the thigh. These muscles are
supplemented by the pectineus. Gracilis is also an adductor
Where does gracilis lie?
This muscle crosses the knee and lies between sartorius and semitendinosus on the medial aspect of the knee
What adductor is in action when the knee is extended?
Gracilis
What adductor muscle is not active when the knee is flexed?
Gracilis
What three muscles are the abductors of the hip?
1. Gluteus medius
2. Gluteus maximus
3. Tensor fascia latae
They act through the iliotibial band
How do you test the strength of the abductors of the hip?
By having the patient lie on their side and raising the leg away from the couch against gravity and resistance
What are you testing when the patient lies on their side and raises the leg away from the couch against gravity and resistance?
The strength of the abductors
What does Trendelenberg's test (stork test) assess?
It tests the stability of the hip and the ability of the hip abductors to stabilise the pelvis on the femur
What tests the stability of the hip and the ability of the hip abductors to stabilise the pelvis on the femur?
Trendelenberg (stork test) test
How do you do the Trendelenberg test?
The patient stands on one leg with the other knee flexed. The pelvis should tilt upwards or stay level on the side of the lifted leg. A positive Trendelenberg sign occurs when the reverse happens; the pelvis tilts downwards indicating weak glutei
What pathology can produce a positive Trendelenberg sign?
Osteoarthritis of the hip
What does Laseque's (straight leg raise) test test?
This test will provoke pain in patients with hamstring muscle inflexibility, severe hip pathology and also tests mobility of nerve roots L4 to S2. Where no pathology is present the leg should make an angle of 70 degrees to the supporting surface
How many degrees to the supporting surface should the leg be in a Laseque's (straight leg raise) test in a normal person?
70 degrees
What other tests can be used to reproduce pain if the formal examination has not reproduced the patient's in the hip?
Functional tests such as single leg squats or step up or step down tests
What functional test can be used to assess pelvic control?
Single leg squat
What does a single leg squat test?
Pelvic control
What is the largest joint in the body?
The knee joint
What two joints comprise the knee joint?
Patellofemoral joint and tibiofemoral joint
What joint is comprised of the patellofemoral joint and the tibiofemoral joint?
The knee joint
What muscles and ligaments provide stability to the knee?
The cruciate and collateral ligaments, the menisci, the iliotibial band and sartorius muscle
What does the patella articulate with?
The anterior surface of the inferior end of the femur
What bone articulates with the anterior surface of the inferior end of the femur
The patella
What sort of bone is the patella?
A sesamoid
What are the ten elements of assessment of the knee?
1. Observation
2. Palpation
3. Patellofemoral joint tests
4. Tibiofemoral joint motion
5. Tibiofemoral joint stability
6. Integrity of internal knee structure
7. Muscle testing
8. Q angle
9. Functional tests
10. Laboratory tests
When observing the knee joint what eight things should you be looking for?
1. Gross deformity (genu valgum/varum, enlarged or abnormal position of tibial tubercle)
2. Patella position ((squinting, fisheye or outward facing, patella alta, patella tilt or rotation)
3. Patella size (small patella unstable in femoral groove, susceptible to subluxation/dislocation)
4. Oedema - the presence and site of swelling in the knee should be noted
5. Tonic muscle spasm (hamstrings) secondary to intra-articular/extra-articular pain
6. Muscle wasting (quadriceps femoris, particularly vasus medialis)
7. Bruising (trauma)
8. Scars (site and evidence will provide evidence of type/extent of surgery
What is patella alta?
A high-riding patella
What is a high-riding patella called?
Patella alta
What 6 conditions can swelling of an extreme nature in the knee be associated with?
1. Bursitis
2. Acute synovitis
3. Tearing of the menisci
4. Rheumatoid arthritis
5. Osteoarthritis
6. Baker's cyst
What is a Baker's cyst?
It is also known as a popliteal cyst and is a benign swelling behind the knee joint
What is haemarthrosis?
A bleeding into the joint
What is bleeding into the joint called?
A haemarthrosis
What is a benign swelling behind the knee joint called?
A Baker's cyst or popliteal cyst
What three conditions can cause spontaneous swelling in the knee joint?
1. Cruciate injury
2. Meniscus injury
3. Haemarthrosis following trauma
What four conditions are muscle wasting around the knee joint associated with?
1. Anterior knee pain
2. Osteoarthritis
3. RA
4. Osgood Schlatter's disease
What is Osgood Schlatter's disease?
The condition occurs in active boys and girls aged 11-15, coinciding with periods of growth spurts. The condition is usually self-limiting and is caused by stress on the patellar tendon that attaches the quadriceps muscle at the front of the thigh to the tibial tuberosity. Following an adolescent growth spurt, repeated stress from contraction of the quadriceps is transmitted through the patellar tendon to the immature tibial tuberosity. This can cause multiple subacute avulsion fractures along with inflammation of the tendon, leading to excess bone growth in the tuberosity and producing a visible lump.
What is Osgood Schlatter's disease also known as?
A tibial tubercle apophyseal traction injury
What is a tibial tubercle apophyseal traction injury also known as?
Osgood Schlatter's disease
What group of diseases does Osgood Schlatter's disease belong to?
Osteochondroses
What ten areas of the knee should be palpated and state what you are palpating for.
1. Palpate for warmth (inflammatory joint disorder)
2. Palpate for oedema (generalised/localised)
3. Palpate joint line medially/laterally for joint, meniscal pathology and anteriorly for coronary ligament pathology
4. Palpate for tendons crossing the knee joint: medially (semitendinosus/semimembranosus); laterally (biceps femoris, iliotibial band); and anteriorly (patellar tendon)
5. Palpate patella - tenderness superior pole (rectus femoris tear or bipartite patella) - pain in body of patella (fracture following trauma) - pain inferior pole of patella (Sinding-Larsen-Johannson syndrome); infrapatella fat pad palpated for tenderness - this fat pad can become impinged between the patellar and femoral condyle following forced extension of the knee (Hoffa's syndrome); however, chronic fat pad impingement (aka infrapatella bursitis) occurs more frequently
6. Popliteal fossa (Baker's cyst, popliteus bursitis, fabella)
7. Tender, enlarged tubercle (Osgood Schlatter's disease)
8. Local oedema
9. Bursae
10. Soft tissue lumps such as lipoma can also be found around the knee
Where are the coronary ligaments of the knee?
Portions of the joint capsule which connect the inferior edges of the fibrocartilaginous menisci to the periphery of the tibial plateaus.
What are the portions of the joint capsule which connect the inferior edges of the fibrocartilaginous mensici to the periphery of the tibial plateaus.
The coronary ligaments of the knee
What tendons cross the joint medially?
Semitendinosus and semimembranosus
Where do semimembranosus and semitendinosus cross the joint, medially or laterally?
Medially
What tendons cross the knee joint laterally?
Biceps femoris and iliotibial band
Where do biceps femoris and the iliotibial band cross the joint, medially or laterally?
Laterally
Where does the patellar tendon cross the knee joint, anteriorly or laterally?
Anteriorly
What tendon cross the knee joint anteriorly?
Patella tendon
What is Sinding-Larsen-Johansson syndrome?
Sinding-Larsen-Johansson syndrome is inflammation of the kneecap (patella) at its lowest point. This is the site of origin of the patellar tendon. There is traction on the kneecap at this point due to action of the large, powerful thigh muscle (quadriceps), as well as with deep bending of the knee. The injury is due to repeated stress or vigorous exercise. It is a temporary condition of the patella that is uncommon after age 16. It is the children’s equivalent of patellar tendinitis (jumper’s knee).
What could be the cause of pain in the lower part of the patella in an active adolescent?
Sinding-Larsen-Johansson syndrome
What is Hoffa's syndrome?
In the case of a forceful direct impact to the kneecap, the fat pad can become impinged (pinched) between the femoral condyle and the patella. As the fat pad is one of the most sensitive structures in the knee, this injury is known to be extremely painful. This condition is normally long-standing as it is aggravated by extension (straightening) of the knee joint. Hence the fat pad comes under constant irritation and may become significantly inflamed.
What other name is Hoffa's syndrome also known as?
Fat pad impingement
What is the infrapatellar fat pad also known as?
Hoffa's pad
Where is the infrapatellar fat pad (Hoffa's pad) situated?
It is soft tissue that lies beneath the patella (kneecap) separating it from the femoral condyle (end of the thigh bone).
What is chronic fat pad impingement also known as?
Infrapatella bursitis
What is infrapatella bursitis also known as?
Chronic fat pad impingement
What is a fabella?
The fabella is a small sesamoid bone found embedded in the tendon of the lateral head of the gastrocnemius muscle behind the lateral condyle of the femur. It is a variant of normal anatomy and present in humans in 10% to 30% of individuals. Rarely, there are 2 or 3 of these bones (fabella bi- or tripartita). It can be mistaken for a loose body or osteophyte.
What is a small sesamoid bone found embedded in the tendon of the lateral head of the gastrocnemius muscle behind the lateral condyle of the femur?
A fabella
Where is the suprapatellar bursa?
Between the quadriceps tendon and femur
What bursa is between the quadriceps tendon and the femur?
The suprapatellar bursa
Where is the prepatellar bursa?
Between the front of the patellar and the skin
What bursa is between the front of the skin and the patellar?
The prepatellar bursa
Where is the infrapatellar bursa?
Between the patellar tendon and proximal tibia
What bursa is between the patellar tendon and the proximal tibia?
The infrapatellar bursa
Where is the pes anserine?
Under the tendinous insertion of gracilis, semitendinosus and gracilis muscles
What is the tendinous insertion under gracilis, semitendinosus and sartorius muscles?
The pes anserine
How many patellofemoral joint tests are there and what are they?
There are 5 and they are:
1. Ballottement test (patellar tap test)
2. Wipe test (fluid displacement test)
3. Apprehension test
4. 50:50 test
5. Clarke's test
What does the Ballottement test (patellar tap test) test for?
It is used to test for moderate intracapsular swelling
What test is used to test for moderate intracapsular swelling of the knee?
The Ballottement test (patellar tap test)
How do you perform the ballottement test (patellar tap test)?
Squeeze excess fluid out of the suprapatellar pouch, place tips of the thumb and three fingers on the patella and jerk it quickly downwards. A floating sensation of the patella over fluid or a click indicates the presence of an effusion
What does the wipe test (fluid displacement test) test for?
This is used to test for slight to moderate intracapsular swelling
What test is used to test for slight to moderate intracapsular swelling?
The wipe test (fluid displacement test)
How do you perform the wipe test (fluid displacement test)?
Evacuate the suprapatellar pouch of fluid then stroke the medial side of the patella. A wave of fluid will bulge on the lateral side of the joint. Stroke the lateral side and observe the medial side of the joint for fluid movement.
What is the apprehension test used for?
To test if the patella is manually displaced laterally
What indicates hypermobility of the patella?
If it can be displaced than 50% of its width both medially and laterally
What does displacement of the patella greater than 50% of its width both medially and laterally indicate?
Hypermobility
How do you perform Clarke's test?
With the patient supine the practitioner places one hand proximal to the superior pole of the patella and asks the patient to contract the quadriceps. This test is used to detect anterior knee pain or patello-femoral pain syndrome.
What is Clarke's test used for?
To test for anterior knee pain
What test is used to test for anterior knee pain?
Clarke's test
What is chondromalacia patellae?
Chondromalacia patellae is a term for a large and disparate group of medical conditions that can cause pain in the front of the knee
Which plane does the main movement happen in the knee?
The sagittal plane
What number of degrees should the knee flex to in a healthy person?
About 135 degrees
How many degrees should the knee extend to in a healthy person?
From 0 degrees to 10 degrees
What is the condition known as when extension of the knee is greater than 10 degrees?
Genu recurvatum
What is genu recurvatum?
When the knee extends more than 10 degrees
Why is flexion of the knee important in gait?
For forward progression
What can genu recurvatum be indicative of?
Lower limb dysfunction or flexed trunk posture
What plane do the lateral and medial ligaments of the knee provide stability in?
The frontal plane
What ligaments provide stability to the knee in the frontal plane?
The frontal plane
Should there be frontal plane motion at the knee?
No
What patient group has frontal plane motion of the knee?
Frontal plane motion is only available to a child under 6 years
What does a lateral collateral ligament stress test (varus stress test) assess?
A lateral stress test is used to assess the lateral collateral ligaments
What test is used to test the lateral collateral ligaments in the knee?
The lateral collateral ligament stress test
How do you perform the lateral collateral ligament stress test (varus stress test)?
With the patient supine the knee is flexed to 30 degrees so the joint is unlocked during the test. The practitioner places one hand on the medial side of the lower end of the femur and the other on the lateral side of the upper end of the tibia. The practitioner then pushes with both hands in an attempt to 'break' the knee by stressing the lateral collateral ligament
Where is the lateral collateral ligament in relation to the biceps femoris tendon?
It is deep to the biceps femoris tendon
What position is it easiest to palpate the lateral collateral ligament in?
The figure-4 position where the patient is seated with the hip maximally externally rotated, the knee flexed to 90 degrees and the foot rested on the top of the distal thigh of the other leg
How is the medial collateral ligament stress test (valgus test) carried out?
By doing the lateral collateral ligament stress test and placing the hand in the opposite position
What does motion at the knee indicate?
Weak collaterals and poor knee stability
Which collateral ligament in the knee is more commonly damaged?
The medial collateral ligament
Who is more likely to damage their collateral ligaments?
Football and rugby players
Who is likely to damage their lateral collateral ligaments?
Ice hockey players
What structures of the knee hold the knee stable in the sagittal plane and prevent the knee "opening up"?
Anterior and posterior cruciate ligaments
What is the function of anterior and posterior cruciate ligaments?
To hold the knee stable in the sagittal plane and to prevent the knee "opening up"
What is the drawer test?
It tests the anterior and posterior cruciate ligaments
What test would be used to test the anterior and posterior cruciate ligaments?
The drawer test
How do you do the drawer test for the anterior cruciate ligament?
The patient lies supine with the knee flexed to 45 degrees and the foot flat on the couch. The practitioner sits on the foot and grasps the upper end of the tibia and pulls it forward to stress the anterior cruciate ligament. More than 2-3cm displacement of the tibia is considered abnormal and may be painful. Excessive movement suggests tearing of these structures.
How do you do the drawer test for the posterior cruciate ligament?
The patient lies supine with the knee flexed to 45 degrees and the foot flat on the couch. The practitioner sits on the foot and grasps the upper end of the tibia and pushes it backward to stress the posterior cruciate ligament. More than 2-3cm displacement of the tibia is considered abnormal and may be painful. Excessive movement suggests tearing of these structures.
Why is the test known as a drawer test?
Because the action is like opening and shutting a drawer
What does Lachman's test test?
The anterior cruciate ligament
How do you perform Lachman's test?
The knee is flexed to 25 degrees and the tibia is pulled forward while the knee is externally rotated. If there is displacement of the tibia this is indicative of a weak anterior cruciate ligament. A positive sign is indicated by a forward translation of the tibia with a mushy/soft end feel.
How many tests are there for the anterior cruciate ligament and what are they?
1. Drawer test
2. Lachman's test
3. The pivot shift test
What does the pivot shift test test?
The anterior cruciate ligament
How do you do the pivot shift test?
With the knee in full extension and the tibia internally rotated, a valgus force is applied to the knee. In an anterior cruciate deficient knee, the condyles will be subluxed. The knee is then flexed, looking for a 'clunk' of reduction, rendering the pivot shift test positive.
What does McMurray's test test?
Meniscus tears or any loose bodies by detecting crepitations and clicking
What test tests for meniscus tears or any loose bodies?
McMurray's test
Which meniscus is most likely to tear?
The medial meniscus
Why is the medical meniscus most likely to tear?
Because it has less flexibility and it is attached to the capsule
How do you perform McMurray's test?
The patient lies supine with the knee and hip flexed to 90 degrees. The practitioner grasps the sole of the foot with one hand; the other should be placed around the knee so that the joint can be palpated. By moving the foot the tibia is externally rotated and a valgus stress is applied. A positive test will elicit a 'popping' or 'snapping' sound or sensation. The test is repeated with internal rotation and a varus stress for the lateral meniscus.
How many tests are there to test for meniscal tears and what are they?
1. McMurray's test
2. Apley's compression test
What does Apley's compression test test?
Meniscus damage
How is Apley's compression test performed?
The patient lies prone and the knee is flexed and the foot grasped. The practitioner creates a compression at the knee joint while producing a rotation movement. A noisy and painful response suggests meniscus damage
Wasting of which muscle occurs as a result of knee dysfunction?
Medial vastus muscle
Where should the circumference of both legs be measured when measuring the quadriceps?
10cm above the superior pole of the patella
What is the function of the rectus femoris muscle?
It is a weak flexor of the hip but a powerful extensor of the knee
What muscle group does rectus femoris belong to?
The quadriceps
How does rectus femoris function within the quadricep group of muscles?
Rectus femoris is an important stabiliser of the knee, in conjunction with the vasti and is needed to swing the leg forward in gait
Where does rectus femoris insert at?
The anterior inferior iliac spine
What muscle is a weak flexor of the hip and a powerful extensor of the knee?
Rectus femoris
How do you examine rectus femoris?
The patient sits on the edge of the couch with the knees flexed. To assess the strength of this muscle the patient is asked to extend the knee while the practitioner attempts to resist this active motion
How are the hamstrings tested?
From an extended knee position the strength of the hamstrings is tested by asking the patient to flex their knee (push down) against resistance.
What test is used to identify tightness and contracture of the hamstring muscle group?
The 90:90 test
What does the 90:90 test test?
It identifies tightness and contracture of the hamstring muscle group
What problems can tight hamstrings cause?
Tight hamstrings may cause knee flexion, creating an inefficient antagonist action with the quadriceps and a functional equinus at the ankle joint
How is the 90:90 test performed?
The patient is supine. The knee and hip are flexed to 90 degrees. The practitioner holds the leg and extends the knee until resistance is met. If the knee can be fully straightened or to within 10 degrees, then the hamstrings are within normal limits. If the leg can only be partially extended it indicates tight hamstrings
How do you assess whether biceps femoris is tight or whether it is semitendinosus?
If the knee is extended as far as possible then medially rotated biceps femoris is being tested. Laterally rotating the extended leg will test semitendinosus.
What is the Q angle?
The Q angle is the position the patella adopts in relation to the direction of pull of the quadriceps tendon
How is the Q angle measured?
A line is drawn from the ASIS to a line bisecting the patella. If the angle of this line to the bisection of the patella is greater than 15 degrees the patient is said to have a high Q angle. This suggests medial displacement of the patella and is often associated with greater than normal internal rotation and anterior knee pain.
If the Q angle is greater than 15 degrees what does this indicate?
A high Q angle
What does a high Q angle mean?
It suggests medial displacement of the patella and is often associated with greater than normal internal rotation and anterior knee pain
What 3 pathologies can X-rays show of the knee?
1. Osteoarthritis
2. Loose bodies
3. A fragmented or bipartite patella
What 3 pathologies can MRI scans show?
1. Thickening or swelling around the tendon
2. The presence of any tendon tears or degeneration
3. Meniscal damage
What could pus in the joint indicate?
Infective arthritis
What would bilateral swelling around the tibiofibular area indicate?
A systemic cause rather than a local cause
What could unilateral leg oedema in women over 40 years indicate?
An intrapelvic neoplasm
What 2 pathologies could local bone swelling indicate?
1. An old fracture
2. Neoplasm eg osteoid osteoma
What is an osteoid osteoma?
A benign bone tumour of the long bones
What is diaphyseal aclasia?
It is multiple or single exostoses that occur in the tibia
What is the name of the condition where there is multiple or single exostoses that occur in the tibia?
Diaphyseal aclasia
What is thickening of the ends of the tibia indicative of?
1. Osteoarthritis
2. Rickets
What is an enlarged and painful tibial tuberosity an indication of?
Osgood Schlatter's disease
What is Brodie's abscess or osteitis?
A Brodie abscess is a subacute osteomyelitis, which may persist for years before converting to a frank osteomyelitis.
What is a subacute osteomyelitis which has persisted for years before converting to frank osteomyelitis called?
Brodie's abscess or osteitis
What could be tenderness over the proximal lateral area of the tibia be indicative of?
Brodie's abscess or osteitis
What is another name for Brodie's abscess?
Osteitis
What is a symptom of Brodie's abscess or osteitis?
Tenderness over the proximal lateral area of the tibia
What could pain in the region of the head of the fibular be indicative of?
Proximal tibiofibular joint osteoarthritis
What is a symptom of proximal tibiofibular joint arthritis?
Pain at the head of the fibular
What is anterior tibial compartment syndrome?
It is a buildup of pressure in the anterior tibial compartment
What does the anterior tibial compartment have in it?
1. Tibialis anterior
2. Extensor digitorum longus
3. Extensor hallucis longus
4. Peroneus tertius
5. Anterior tibial artery
6. Deep peroneal nerve
What is the compartment called which has these elements in it?
1. Tibialis anterior
2. Extensor digitorum longus
3. Extensor hallucis longus
4. Peroneus tertius
5. Anterior tibial artery
6. Deep peroneal nerve
Anterior tibial compartment
What could be indicative of pain over the anterior tibial border?
Stress fracture
What could pain over the medial border of the tibia be indicative of?
Medial tibial stress syndrome
What could pain over the inferior tibiofibular joint be associated with?
Lateral ligament injury and may cause anterior ankle pain
What could tenderness in the back of the calf be indicative of?
Ruptured plantaris tendon syndrome
What could pain over the tendocalcaneus be indicativ of?
A partial or complete rupture of the Achilles tendon
What test do you perform to test if there is Achilles tendon rupture?
Thomson's test
How do you perform Thomson's test?
With the patient prone squeeze the calf. If no plantarflexion occurs a complete rupture of the Achilles tendon is indicated
What is the test called that squeezes the calf to test for Achilles tendon rupture?
Thomson's test
When is Thomson's test contraindicated?
When there is an index of suspicion that there might be a DVT
What are the two frontal plane deformities in the tibia?
Tibial varum and tibial valgum
How do you test for tibial varum or tibial valgum?
The patient is in the supine position by bringing the legs together and observing the relative distance between the knees and the malleoli. A greater distance between the knees is seen in tibial varum
When testing for tibial varum or valgum what does a greater distance between the knees than the malleoli indicate?
Tibial varum
Which is more common, tibial varum or tibial valgum?
Tibial varum
What is tibial varum
Where there is a greater distance between the knees than the malleoli
What number of degrees is considered normal in tibial varum?
About 6 degrees
What is the factor that can cause lessening of the lower limb problems associated with tibial varum?
The ability of the STJ to compensate
What is the eight finger test?
It estimates the degree of frontal plane bowing of the tibia (tibial varum)
What test can be used to estimate the degree of frontal plane bowing of the tibia?
The eight finger test
How do you perform the eight finger test?
All eight fingers are placed along the anterior border of the tibia and their alignment compared
What does sagittal plane bowing (sabre tibia) and general tibial thickening indicative of?
Paget's disease
When is the onset of Paget's disease?
60-70 years old
What is Paget's disease (osteitis deformans)?
Paget's disease, otherwise known as osteitis deformans, is a chronic disorder that typically results in enlarged and deformed bones.
What is another name for Paget's disease?
Osteitis deformans
What is another name for osteitis deformans?
Paget's disease
What is sagittal plane bowing called?
Sabre tibia
What is sabre tibia?
Sagittal plane bowing
What are the transverse plane deformities of the tibia?
Medial tibial torsion and lateral tibial torsion
What plane is medial tibial torsion and lateral plane torsion in?
The transverse plane
What two problems are medial tibial torsion associated with?
1. Flat feet
2. Intoeing deformities
What roblem is lateral torsion associated with?
Pes cavus feet
What test is used to test for the relative lengths of the tibiae?
Skyline/Allis test
What is the Skyline/Allis test?
It tests the relative lengths of the tibiae
How do you perform the Skyline/Allis test?
With patient supine and knees flexed and the soles of the feet on the couch, the relative lengths of the tibiae can be assessed by comparing the heights of the knees or tibial tuberosities
What comprises the ankle joint?
The talocrural joint and the subtalar joint
How many joints are there in the ankle?
Two
What is the inferior tibiofibular joint?
It is a syndesmosis supported by the inferior tibiofibular ligament
What are the two most common coalitions seen at the ankle joint?
The talocalcaneal joint (medial and posterior facets) and the calcaneonavicular joint.
What three types of tissue can be involved in coalitions?
1. Fibrous coalition
2. Cartilaginous coalition
3. Osseous coalition
What movement and symptoms can be seen in a fibrous coalition?
Some movement and few symptoms
What movement and symptoms can be seen in a cartilaginous coalition?
No movement but more symptoms
What movement and symptoms can be seen in an osseous coalition (synostosis)?
No movement but more symptoms
What is a common symptom of tarsal coalitions?
Tonic spasms of the peronei
What could cause tonic spasm of the peronei?
Tarsal coalitions
How do you definitely diagnose an osseous tarsal coalition (synostosis)?
By X-ray
What is a synostosis?
An osseous tarsal coalition
What is another name for an osseous tarsal coalition?
A synostosis
What bones and articulations form the talocrural joint?
The trochlear surface of the talus articulates with the inferior surface of the tibia to form the talocrural joint
What is a function of the medial and lateral malleoli?
They provide additional articulations and stability to the ankle joint
What is the talocrural joint, biplanar or triplanar?
Triplanar
In which plane is the main motion of the ankle joint?
Sagittal plane
How many degrees of dorsiflexion should there be in the ankle?
10 degrees
Why do you need 10 degrees of dorsiflexion in the ankle?
To allow the leg to move over the foot
What three areas can the body compensate for a lack of dorsiflexion?
1. Knee
2. Subtalar joint
3. Midtarsal joint
What can the knee do to compensate for lack of dorsiflexion at the ankle?
The knee can hyperextend (genu recurvatum) to compensate for an ankle equinus
What six things should be assessed for at the talocrural joint?
1. Range of motion
2. Stability
3. Strength
4. Palpation for tenderness
5. Grading of ligamentous injury
6. Proprioception
How do you assess dorsiflexion range of motion non-weightbearing?
The patient should lie prone or spine with the knee extended and the foot and ankle free of the end of the couch. The practitioner holds the foot in neutral with one hand, places the other hand on the sole of the foot and dorsiflexes the ankle. If subtalar joint pronation is allowed to occur during the examination a falsely elevated dorsiflexion value will result.
What is the problem of testing dorsiflexion range of motion non-weightbearing?
The force applied by the practitioner to TCJ dorsiflexion can vary
What two things may prevent TCJ dorsiflexion?
1. A tight soleus
2. A tight gastrocnemius
How do you differentiate between a tight gastrocnemius and a tight soleus?
The amount of the dorsiflexion with the knee extended and flexed should be measured. With the knee flexed the tendons of gastrocnemius which cross the knee are released from tension so gastrocnemius affect TCJ dorsiflexion. If the amount of dorsiflexion is still reduced when the knee is flexed the cause is likely to be soleus. However a bony block (osteophytes on the distal/anterior tibia) can also limit TCJ dorsflexion with the knee flexed however the Achilles tendon in this case will feel slack.
What other conditions can affect TCJ dorsiflexion with the knee flexed?
A bony block (osteophytes on distal on the distal/anterior tibia) can also limit TCJ dorsflexion with the knee flexed however the Achilles tendon in this case will feel slack.
Describe the two types of feeling you expect to get from TCJ end ROM when testing dorsiflexion
1. Soft tissue limitation will result in a springy end-feel
2. Limitation resulting from a bony block will be abrupt
What is a more consistent way of testing TCJ dorsiflexion, weight-bearing or non-weight-bearing?
Weight-bearing
How do you test weight-bearing TCJ dorsiflexion?
The patient stands facing a wall with a distance of approximately 0.5m between the patient and the wall. One leg, with the knee in a flexed position, is placed in front, approximately 30cm from the wall. The other leg is placed behind the forward foot with the knee extended and the foot held in a neutral position. The patient leans forward and places both hands on the wall and is asked to move his body towards the wall. In order to do this the patient must dorsiflex the ankle of the limb furthest from the wall.
What are the lateral ligaments in the ankle.?
Calcaneofibular and talofibular ligements
What test tests the integrity of the anterior talofibular ligament?
The ankle drawer test
How do you do the ankle drawer test?
The foot is flat on the couch and a forward and backward motion should be applied to the TCJ
What does the ankle drawer test test?
The integrity of the anterior talofibular ligament
What does the talar tilt test assess?
It assesses the integrity of the calcaneofibular ligament laterally and the deltoid ligament medially
How do you perform the talar test?
Wit the patient supine the calcaneus is grasped and moved medially and laterally. The medial and lateral movement of the talus and calcaneus is assessed in relation to the tibia and fibular
What is TELOS?
It is a stress X-ray using a German system which allows the ankles to be compared. The procedure is performed under LA using a common peroneal nerve block. It provides a reproducible method to determine ankle stability
How many muscles are there in the gluteal region and what are they?
There are 8
1. Gluteus maximus
2. Gluteus medius
3. Gluteus minimus
4. Piriformis
5. Quadratus femoris
6. Obturator internus
7. Gemellus superior and inferior
8. Obturator externus
What is the function of gluteus maximus?
Extension and lateral rotation of the hip joint
Where does gluteus maximus go from?
Gluteus maximus goes from the posterior gluteal line of the hip bone, the dorsal surface of the lower part of the sacrum and the side of the coccyx, the sacrotuberous ligament and the fascia over the gluteus medius.
Where does gluteus maximus go to?
Gluteus maximus goes to the iliotibial tract with the deep fibres of the lower part attaching to the gluteal tuberosity of the femur
What is the function of gluteus medius?
Abduction and medial rotation of the hip joint and prevention of adduction
Where does gluteus medius go from?
Gluteus medius goes from the outer surface of the ilium between the posterior and anterior oblique lines
Where does gluteus medius go to?
Gluteus medius goes to the lateral surface of the greater trochanter of the femur
What is the function of gluteus minimus?
Abduction and medial rotation of the hip joint and prevention of adduction
Where does gluteus minimus go from?
Gluteus minimus goes from the outer surface of the ilium between the anterior and inferior gluteal lines
Where does gluteus minimus go to?
Gluteus minimus goes to the anterior part of the lateral surface of the greater trochanter of the femur
What is the function of piriformis?
Abduction, lateral rotation and stabilization of the hip joint
Where does piriformis go from?
Piriformis goes from the middle three pieces of the sacrum
Where does piriformis go to?
Piriformis goes to the upper border of the greater trochanter of the femur
What is the function of quadratus femoris?
Lateral rotation and stabilization of the hip joint
Where does quadratus femoris go from?
From the upper part of the outer border of the ischial tuberosity
Where does quadratus femoris go to?
To the quadrate tubercle of the intertrochanteric crest of the femur
What is the function of obturator internus?
Lateral rotation and stabilization of the hip
Where does obturator internus go from?
Obturator internus goes from the inner surface of the obturator membrane and the adjacent anterolateral pelvic wall
Where does obturator internus go to?
Obturator internus goes to the greater trochanter of the femur above and in front of the intertrochanteric fossa
What is the function of gemellus superior and inferior?
Assists obturator internus
Where does gemellus superior go from?
Gemellus superior goes from the dorsal surface of the ischial spine.
Where does gemellus superior go to?
Gemellus superior goes to the superior borders of obturator internus
Where does gemellus inferior go from?
Gemellus inferior goes from the upper part of the ischial tuberosity
Where does gemellus inferior go to?
Gemellus inferior goes to the inferior borders of obturator internus
What is the function of obturator externus?
Lateral rotator of the thigh
Where does obturator externus go from?
Obturator externus goes from the outer surface of the obturator membrane and the ischiopubic ramus
Where does obturator externus go to?
Obturator externus goes to the trochanteric fossa of the femur
How many muscles are there in the front of the thigh and what are they?
There are 9 muscles
1. Iliacus
2. Psoas major
3. Tensor fasciae latae
4. Sartorius
5. Rectus femoris
6. Vastus lateralis
7. Vastus medialis
8. Vastus intermedias
9. Articularis genus
What is the function of iliacus?
Flexor of the hip, assisting psoas major
Where does iliacus go from?
Iliacus goes from the upper two-thirds of the iliac fossa in the lower abdomen
Where does iliacus go to?
Iliacaus goes to the psoas tendon and the femur below and in front of the lesser trochanter
What is the function of psoas major?
Flexor of the hip
Where does psoas go from?
Psoas goes from the sides of the lumbar vertebrae and intervertebral discs
Where does psoas go to?
Psoas goes to the lesser trochanter of the femur
What is the function of tensor fasciae latae?
Extensor of the knee and lateral rotator of the leg
Where does tensor fasciae latae go from?
Tensor fasciae latae goes from the anterior 5cm of the outer lip of the iliac crest
Where does tensor fasciae latae go to?
Tensor fasciae latae goes to the iliotibial tract
What is the function of sartorius?
Flexor, adductor and lateral rotator of the hip
Where does sartorius go from?
Sartorius goes from the anterior superior iliac spine
Where does sartorius go to?
Sartorius goes to the upper part of the medial surface of the shaft of the tibia in front of gracilis and semitendinosus
What is the function of rectus femoris?
Flexor of the hip and extensor of the knee
Where does rectus femoris go from?
Rectus femoris goes from the anterior inferio iliac spine (straight head) and the ilium above the rim of the acetabulum (reflected head)
Where does rectus femoris go to?
Rectus femoris goes to the base of the patella
What is the function of vastus lateralis?
Extensor of the knee
Where does vastus lateralis go from?
Vastus lateralis goes from the upper part of the intertrochanteric line of the femur, anterior and inferior borders of the greater trochanter, lateral lip of the gluteal tuberosity and the upper part of the linea aspera
Where does vastus lateralis go to?
Vastus lateralis goes to the lateral border of the patella and the quadriceps tendon
What is the function of vastus medialis?
Extensor of the knee
Where does vastus medialis go from?
Vastus medialis goes from the lower part of the intertrochanteric line of the femur, the spiral line, the linea aspera, the upper part of the medial supracondylar line and the tendon of adductor magnus
Where does vastus medialis go to?
Vastus medialis goes to the medial border of the patella and the quadriceps tendon
What is the function of vastus intermedius?
Extension of the knee
Where does vastus intermedius go from?
Vastus intermedius goes from the anterior and lateral surfaces of the upper two-thirds of the shaft of the femur
Where does vastus intermedius go to?
Vastus intermedius goes to the deep part of the quadriceps tendon
What is the function of the articularis genus?
Retraction of the bursa as the knee extends
Where does articular genus goes from?
Articular genus goes from the anterior surface of the femur below vastus intermedius
Where does articularis genus go to?
Articularis genus goes to the apex of the suprapatellar bursa
How many muscles are there in the medial thigh and what are they?
There are 5 muscles
1. Pectineus
2. Gracilis
3. Adductor brevis
4. Adductor longus
5. Adductor magnus
What is the function of pectineus?
Flexor, adductor and lateral rotator of the thigh
Where does pectineus go from?
The pectineus goes from the pectineal line of the pubis and bone in front of the line
Where does pectineus go to?
Pectineus goes to the femur on a line from the lesser trochanter to the linea aspera
What is the function of gracilis?
Flexor, adductor and medial rotator of the thigh
Where does gracilis go from?
Gracilis goes from the body of the pubis and ischiopubic ramus
Where does gracilis go from?
Gracilis goes from the body of the pubis and ischiopubic ramus
Where does gracilis go to?
Gracilis goes to the upper part of the medial surface of the shaft of the tibia between sartorius and semitendinosus
What is the function of adductor brevis?
Adductor of the thigh
Where does adductor brevis go from?
Adductor brevis goes from the body and inferior ramus of the pubis
Where does adductor brevis go to?
Adductor brevis goes to the shaft of the femur on a line from the lesser trochanter to the linea aspera and to the upper part of the linea
What is the function of adductor longus?
Adductor of the thigh
Where does adductor longus go from?
Adductor longus goes from the front of the pubis
Where does adductor longus go to?
Adductor longus goes to the middle part of the linea aspera
What is the function of adductor magnus?
Adductor and lateral rotator of the thigh
Where does adductor magnus go from?
Adductor magnus goes from the lower lateral part of the ischial tuberosity and the ischiopubic ramus
Where does adductor magnus go to?
Adductor magnus goes to the shaft of the femur from the gluteal tuberosity along the linea aspera to the medial supracondylar line and to the adductor tubercle
How many muscles are there at the back of the thigh and what are they?
There are three
1. Biceps femoris
2. Semitendinosus
3. Semimembranosus
What is the function of biceps femoris?
Flexion and lateral rotation of the knee and extension of the hip
Where does biceps femoris go from?
Biceps femoris goes from the medial facet of the ischial tuberosity with semimembranosus (long head) and from the linea aspera and lateral supracondylar line of the femur (short head)
Where does biceps femoris go to?
Biceps femoris goes to the head of the fibula
What is the function of semitendinosus?
Flexion and medial rotation of th knee and extension of the hip
Where does semitendinosus go from?
Semitendinosus goes from the medial facet of the ischial tuberosity with the long head of biceps
Where does semitendinosus go to?
Semitendinosus goes to the upper part of the subcutaneous surface of the tibia behind gracilis
What is the function of semimembranosus?
Flexion and medial rotation of the knee and extension of the hip
Where does semimembranosus go from?
Semimembranosus goes from the lateral facet of the ischial tuberosity
Where does semimembranosus go to?
Semimembranosus goes to the groove on the back of the medial condyle of the tibia with expansions forming the oblique popliteal ligament and the fascia over popliteus
How many muscles are there in the front of the leg and what are they?
There are four muscles
1. Tibialis anterior
2. Extensor hallucis longus
3. Extensor digitorum longus
4. Peroneus tertius
What is the function of tibialis anterior?
Dorsiflexion and inversion of the foot
Where does tibialis anterior go from?
The tibialis anterior goes from the upper two-thirds of the lateral surface of the tibia and adjoining part of the interosseous membrane
Where does tibialis anterior go to?
Tibialis anterior goes to the medial surface of the medial cuneiform and base of the first metatarsal
What is the function of extensor hallucis longus?
Extension of the great toe and dorsiflexion of the foot
Where does extensor hallucis longus go from?
Extensor hallucis longus goes from the middle third of the medial surface of the fibula
Where does extensor hallucis longus go to?
Extensor hallucis longus goes to the base of the distal phalanx of the great toe
What is the function of extensor digitorum longus?
Extension of the second to fifth toes and dorsiflexion of the foot
Where does extensor digitorum longus go from?
Extensor digitorum longus goes from the upper two-thirds of the medial surface of the fibula
Where does extensor digitorum longus go to?
Extensor digitorum longus goes to the four lateral toes by the dorsal digital expansions attached to the middle and distal phalanges
What is the function of peroneus tertius?
Dorsiflexion and eversion of the foot
Where does peroneus tertius go from?
Peroneus tertius goes from the lower third of the medial surface of the fibula, continuous with extensor digitorum longus
Where does peroneus tertius go to?
Peroneus tertius goes to the shaft of the fifth metatarsal
What is the muscle on the dorsum of the foot?
Extensor digitorum brevis
Where does extensor digitorum brevis go from?
Extensor digitorum brevis goes from the upper surface of the calcaneus
Where does extensor digitorum brevis go to?
Extensor digitorum brevis goes to the base of the proximal phalanx of the great toe (as extensor hallucis brevis) and the dorsal digital expansions of the second to fourth toes
What is the function of extensor digitorum brevis?
Extension of the first to fourth toes
How many muscles are there on the lateral side of the leg and what are they?
There are two muscles
1. Peroneus longus
2. Peroneus brevis
What is the function of peroneus longus?
Plantarflexion and eversion of the foot
Where does peroneus longus go from?
Peroneus longus goes from the upper two-thirds of the fibula
Where does peroneus longus go to?
Peroneus longus goes to the lateral sides of the medial cuneiform and base of the first metatarsal
What is the function of peroneus brevis?
Plantarflexion and eversion of the foot
Where does peroneus brevis go from?
Peroneus brevis goes from the lower two thirds of the lateral surface of the fibula
Where does peroneus brevis go to?
Peroneus brevis goes to the tuberosity of the base of the fifth metatarsal
How many muscles are there at the back of the leg and what are they?
There are 7 muscles at the back of the leg
1. Gastrocnemius
2. Soleus
3. Plantaris
4. Popliteus
5. Tibialis posterior
6. Flexor hallucis longus
7. Flexor digitorum longus
What is the function of gastrocnemius?
Plantarflexion of the foot and flexion of the knee
Where does gastrocnemius go from?
The medial head goes from the upper posterior part of the medial condyle of the femur. The lateral head goes from the lateral surface of the lateral condyle of the femur
Where does gastrocnemius go to?
Gastrocnemius goes to the middle of the posterior surface of the calcaneus by the tendo calcaneus in association with soleus
What is the function of soleus?
Plantarflexion of the foot
Where does soleus go from?
Soleus goes from the soleal line and upper part of the medial border of the tibia, a tendinous arch over the popliteal vessels and tibial nerve and the upper part of the posterior surface of the fibula
Where does soleus go to?
Soleus goes to the tendo calcaneus with gastrocnemius
What is the function of plantaris?
Plantarflexion of the foot and weak flexion of the knee
Where does plantaris go from?
Plantaris goes from the lateral supracondylar line of the femur
Where does plantaris go to?
Plantaris goes to the calcaneus on the medial side of the tendocalcaneus
What is the function of popliteus?
Lateral rotation of the femur on the fixed tibia (or medial rotation of the tibia on the fixed femur). Pulls lateral meniscus backward during flexion of the knee
Where does popliteus go from?
Popliteus goes from the back of the tibia above the soleal line
Where does popliteus go to?
Popliteus goes to the outer surface of the lateral epicondyle of the femur
What is the function of tibialis posterior?
Plantarflexion and inversion of the foot
Where does posterior tibialis go from?
Tibialis posterior goes from the posterior surface of the interosseous membrane and adjacent posterior surfaces of the tibia and fibula
Where does posterior tibialis go to?
Posterior tibialis goes to the tuberosity of the navicular with slips to other tarsal bones (except the talus) and the middle three metatarsals
What is the function of flexor hallucis longus?
Plantarflexion of the great toe and foot
Where does flexor hallucis longus go from?
Flexor hallucis longus goes from the lower two thirds of the posterior surface of the fibula
Where does flexor hallucis longus go to?
Flexor hallucis longus goes to the plantar surface of the base of the distal phalanx of the great toe
What is the functioin of flexor digitorum longus?
Plantarflexion of the four lateral toes and the foot
Where does flexor digitorum longus go from?
Flexor digitorum longus goes from the medial part of the posterior surface of the tibia below the soleal line
Where does flexor digitorum longus go to?
Flexor digitorum longus goes to the four lateral toes by a tendon to each, reaching the plantar surface of the base of the distal phalanx
How many muscles are in the first layer of the foot and what are they?
There are three muscles
1. Abductor hallucis
2. Flexor digitorum brevis
3. Abductor digiti minimi
What is the function of abductor hallucis?
Abduction and plantarflexion of the great toe
Where does abductor hallucis go from?
Abductor hallucis goes from the medial process of the calcanean tuberosity and the plantar aponeurosis
Where does abductor hallucis go to?
Abductor hallucis goes to the medial side of the proximal phalanx of the great toe
What is the function of flexor digitorum brevis?
Plantarflexion of the four lateral toes
Where does flexor digitorum brevis go from?
Flexor digitorum brevis goes from the medial process of the calcanean tuberosity and the deep surface of the central part of the plantar aponeurosis
Where does flexor digitorum brevis go to?
Flexor digitorum brevis goes to the lateral four toes by a tendon to each. The tendon divides into two slips (to allow the flexor digitorum longus tendon to pass between them) which are attached to the sides of the middle phalanx
What is the function of abductor digiti minimi?
Abduction and plantarflexion of the fifth toe
Where does the abductor digiti minimi go from?
Abductor digiti minimi goes from the lateral and medial processes of the calcanean tuberosity and the plantar aponeurosis
Where does abductor digiti minimi go to?
Abductor digiti minimi goes to the lateral side of the base of the proximal phalanx of the fifth toe (with flexor digiti minimi brevis)
How many muscles are in the second layer of the foot and what are they?
There are two muscles
1. Quadratus plantae
2. Lumbricals
What is the function of quadratus plantae?
Assistance with plantarflexion of the four lateral toes
Where does the quadratus plantae go from?
The quadratus plantae goes from the concave medial surface of the calcaneus and from the plantar surface of the calcaneus in front of the lateral process of the tuberosity
Where does quadratus plantae go to?
Quadratus plantae goes to the lateral border of flexor digitorum longus before the division into four tendons
What is the function of the lumbricals?
Plantarflexion at the four lateral MTPJs and extension at the interphalangeal joints
Where does the first lumbrical go from?
The first lumbrical goes from the medial border of the first tendon of flexor digitorum longus
Where does the first lumbrical go to?
The first lumbrical goes to the medial sides of the dorsal digital expansions of the tendons of extensor digitorum longus
Where do the 2nd, 3rd and 4th lumbricals go from?
The 2nd, 3rd and 4th lumbricals go from the four adjoining tendons of flexor digitorum longus
Where do the 2nd, 3rd and 4th lumbricals go to?
The 2nd, 3rd and 4th lumbricals go to the medial sides of the dorsal digital expansions of the tendons of extensor digitorum longus
How many muscles are in the third layer of the foot and what are they?
There are three muscles in the third layer of the foot
1. Flexor hallucis brevis
2. Adductor hallucis
3. Flexor digiti minimi brevis
What is the function of flexor hallucis brevis?
Plantarflexion of the MTPJ of the great toe
Where does flexor hallucis brevis go from?
Flexor hallucis brevis goes from the plantar surface of the cuboid and lateral cuneiform
Where does flexor hallucis brevis go to?
Flexor hallucis brevis goes by a tendon to each side of the base of the proximal phalanx of the great toe, the medial tendon joining with that of abductor hallucis and the lateral with adductor hallucis. There is a sesamoid bone in each tendon
What is the function of adductor hallucis?
Adduction of the great toe
Where does adductor hallucis go from?
The oblique head goes from the bases of the second, third and fourth metatarsals and the transverse head from the plantar MTP ligaments of the third, fourth and fifth toes
Where does adductor hallucis go to?
Adductor hallucis goes to the lateral side of the base of the proximal phalanx of the great toe with part of flexor hallucis brevis
What is the function of flexor digiti minimi brevis?
Plantarflexion of the MTPJ of the 5th toe
Where does flexor digiti minimi brevis go from?
Flexor digiti minimi brevis goes from the plantar surface of the base of the 5th metatarsal
Where does flexor digiti minimi brevis go to?
Flexor digiti minimi brevis goes to the lateral side of the base of the proximal phalanx of the 5th toe with abductor digiti minimi
How many muscles are there in the fourth layer of the foot and what are they?
There are seven
1. Dorsal interossei (four)
2. Plantar interossei (three)
What is the function of the four dorsal interossei?
Plantarflexion of the MTPJs and extension of the IPJs of the 2nd, 3rd and 4th toes and abduction of the same toes
Where do the four dorsal interossei go from?
The four dorsal interossei go from the adjacent sides of the bodies of the metatarsals
Where do the four dorsal interossei go to?
The four dorsal interossei go to the bases of proximal phalanges and the dorsal digital expansions. 1st and 2nd to the medial and lateral sides of the 2nd toe; 3rd and 4th to the lateral sides of the 3rd and 4th toes
What is the function of the three plantar interossei?
Plantarflexion of the MTPJs and extension of the IPJs of the 3rd, 4th and 5th toes and adduction of the same toes
Where do the three plantar interossei go from?
The three plantar interossei go from the bases and medial sides of the 3rd, 4th and 5th metatarsals
Where do the three plantar interossei go to?
The three plantar interossei go to the medial sides of the bases of the proximal phalanges and dorsal digital expansions of the corresponding toes
What nerves go down the front of the leg?
1. Femoral nerve
2. Saphenous nerve
3. Common peroneal nerve
4. Superficial peroneal nerve
5. Deep peroneal nerve
What nerves go down the back of the leg?
1. Sciatic nerve
2. Tibial nerve
3. Sural nerve
4. Medial plantar nerve
5. Lateral plantar nerve
What are the arteries in the leg?
1. External iliac artery
2. Femoral artery
3. Profunda femoris artery
4. Medial and lateral circumflex femoral arteries
5. Popliteal artery
6. Genicular arteries
7. Posterior tibial artery
8. Peroneal artery
9. Anterior tibial artery
10. Arcuate artery (dorsum)
11. Plantar arch
12. Dorsalis pedis artery
What are the deep and superficial veins of the lower limb?
1. External iliac vein
2. Femoral vein
3. Profunda femoris vein
4. Popliteal vein
5. Knee veins
6. Peroneal vein
7. Anterior tibial vein
8. Posterior tibial vein
9. Great saphenous vein
10. Small saphenous vein
What functional test would you use to test weightbearing dorsiflexion and anterior impingement syndromes?
The lunge test
What would the lunge test be used to tes?
Weightbearing dorsiflexion and anterior impingement syndromes
What is used to test tibialis posterior dysfunction syndrome?
The single limb heel raise test
What does the single limb heel raise test test?
Posterior tibialis dysfunction syndrome
What is Stieda's process?
It is the posterior process of the talus
What is the posterior process of the talus called?
Stieda's process
What order are the three parts of the lateral ligament usually damaged?
1. The anterior talofibule ligament
2. The calcaneofibular ligament
3. The posterior talofibular ligament
What are the three grades used to grade lateral ligament injuries?
1. Grade 1 = minor ATFL tear with pain but no laxity
2. Grade 2 = painful if stressing ligament with laxity but firm end-point
3. Grade 3 = gross laxity without discernible end-point
What Grade is a minor ATFL tear with pain but no laxity?
Grade 1
What Grade is a minor ATFL tear with pain but no laxity?
Grade 1
What Grade is a painful ligament but when stressing is lax but has a firm end-point
Grade II
What Grade is a gross laxity without discernible end-point lateral ligament?
Grade 3
Where is the interosseous talocalcaneal ligament situated?
In the sinus tarsi
What ligament is situated in the sinus tarsi?
The interosseous talocalcaneal ligament situated
What are the angles of the axes of the subtalar joint?
1. 42 degrees from the transverse plane
2. 45 degrees from the frontal plane
3. 16 degrees from the sagittal plane
If the distal fibular is tender what could this be indicative of?
Fracture
If the lateral malleolus is tender what could this be indicative of?
Fracture
If the lateral ligaments are tender what could this be indicative of?
Anterior talofibular ligament/calcaneofibular ligament (ATFL/CFL) sprain due to forced inversion/plantarflexion. Complete tear of ATFL, CFL and posterior talofibular ligament (PTFL) follows an ankle fracture
If the lateral aspect of the talus is tender what could this be indicative of?
Fracture to lateral process of talus
If the posterior aspect of talus is tender what could this be indicative of?
Fracture to posterior process of talus or os trigonum fracture
If the peroneal tendon is tender what could this be indicative of?
Peroneal tendonitis due to excessive eversion, peroneal dislocation due to forced passive dorsiflexion and tearing of peroneal retinaculum or peroneal rupture
If the base of the 5th metatarsal is tender what could this be indicative of?
Avulsion fracture due to inversion injury
If the anterior joint line of the ankle is tender what could this be indicative of?
Articular damage (OA)
If the dome of the talus is tender what could this be indicative of?
Osteochondral fracture associated with compressive component of inversion injury (landing from a jump)
If the tibialis anterior is tender what could this be indicative of?
Tibialis anterior tendinitis due to overuse of ankle dorsiflexors secondary to restriction in joint range of motion
If the posterior medial malleolus is tender what could this be indicative of?
Entrapment of posterior tibial nerve (tarsal tunnel syndrome) due to inversion injury or excessive pronation
If the medial malleolus is tender what could this be indicative of?
Stress fracture
If the medial (deltoid) ligament is tender what could this be indicative of?
Ligament sprain associated with fractured medial malleolus, talar dome
If the tibialis posterior tendon is tender what could this be indicative of?
Tibialis posterior tendinitis (pain is exacerbated by excessive eversion)
If the sustentaculum tali is tender what could this be indicative of?
Flexor hallucis longus tendinitis (pain aggravated by resisted flexion of hallux or full dorsiflexion of hallux)
If the sinus tarsi is tender what could this be indicative of?
Excessive subtalar joint pronation or ankle sprain
If the anterior inferior talofibular ligament is tender what could this be indicative of?
The anterior inferior talofibular ligament (AITFL) is damaged in more severe ankle injuries. Occasionally associated with malleolar fractures
What is abnormal pronation?
Excessive STJ pronation during contact phase and/or STJ pronation occurring when the STJ should be supinating during midstance and propulsion.
What abnormal plane motion in the foot affects the ankle and forefoot?
A large degree of frontal plane motion (inversion/eversion)
What part of the lower limb does a large degree of frontal plane motion affect?
Inversion/eversion
What abnormal plane motion in the tibia affects the knee and leg?
Transverse plane tibial rotation (tibial torsion)
What part of the lower limb does a large degree of transverse plane tibial rotation affect?
It is thought to affect the leg and the knee
What are the 7 indicators of abnormal pronation?
1. More than 6 degrees between the relaxed calcaneal stance position (RCSP) and the neutral calcaneal stance position (NCSP)
2. Medial bulging of the talar head or 'midtarsal break' - quantified using the navicular drift technique (Menz 1998)
3. lowering of the medial longitudinal arch - quantified using the navicular drift technique (Mueller et al 1993)
4. More than 4 degrees eversion of the calcaneus
5. Helbing's sign (medial bowing of the tendo Achilles)
6. Abduction of the foot at the MTJ (concavity of lateral border of foot)
7. apropulsive gait.
Four or more of these indicates abnormal pronation
What are the 7 conditions which may lead to abnormal pronation?
1. Internal or external torsion of the leg/thigh
2. Tibial (genu) valgum/varum
3. Coxa vara/valga
4. Ankle equinus
5. Rearfoot varus
6. Inverted forefoot
7. Everted forefoot
What is the action of the plantarflexors?
The posterior group of muscles plantarflex the foot at the ankle but may also restrict the amount of dorsiflexion at the ankle
What is the test to assess normal action of the Achilles tendon?
The foot should plantarflex when the calf muscle is squeezed
Is plantaris present in everyone?
No
What could be indicative of a painful medial swelling over the posterior aspect of the calcaneus at its insertion near the Achilles tendon?
Rupture of plantaris
What are the signs that plantaris has ruptured?
A painful medial swelling over the posterior aspect of the calcaneus at its insertion near the Achilles tendon?
What are the main invertors of the foot?
Tibialis posterior and tibialis anterior
What is the main action of tibialis posterior and tibialis anterior?
They are the main invertors of the foot
What role do tibialis posterior and tibialis anterior play during gait?
They play an important role in resupinating the foot during midstance and propulsion
What are the main dorsiflexors of the foot?
The long extensors and tibialis anterior
How should the dorsiflexors be tested?
The patient should be asked to dorsiflex the ankle with the foot in inversion against resistance
How much stronger are the plantarflexors than the dorsiflexors in the foot?
About 4.5 times stronger
What happens if the dorsiflexors of the foot are weak?
The foot is held in a plantarflexed position as the plantarflexors have a mechanical advantage
What are the everters of the foot?
The peronei
What is the action of the peronei?
Eversion of the foot
Which are the stronger, everters or inverters of the foot?
The inverters of the foot
What happens to the peroneals in tarsal coalition?
They are in tonic spasm
What can be done to differentiate between tarsal coalition and muscle spasm?
An LA can be administered.
What is the MTJ comprised of?
The talonavicular joint and the calcaneocuboid joint
What is the talonavicular joint and the calcaneocuboid joint called?
The MTJ
What is the MTJ also known as?
The transtarsal or Chopart's joint
What is the transtarsal joint or Chopart's joint known as?
The MTJ
What is the articulation between the forefoot and the rearfoot called?
The MTJ
What is the MTJ joining?
The rearfoot and the midfoot
How many axes does the MTJ have and what are they?
Two, longitudinal and oblique axis
What motion is provided by the longitudinal axis?
Frontal plane motion
How is frontal plane motion facilitated in the MTJ?
It is facilitated by the ball and socket joint of the talonavicular articulaton
What plane of motion is caused by the ball and socket joint of the talonavicular articulation?
Frontal plane of motion
What motion is provided by the oblique axis?
It primarily produces transverse plane and sagittal plane motion
How is transverse plane and sagittal plane motion facilitated in the MTJ?
By involvement of both talonavicular and calcaneocuboid joints
What plane of motion is caused by the involvement of both talonavicular and calcaneocuboid joints?
Transverse plane of motion
If there are limitations at the ankle, how could the foot compensate for this?
The foot compensates at the oblique axis of the MTJ
What axis does compensation occur in the MTJ if there are limitations at the ankle?
At the oblique axis
What are the three functions of the MTJ?
1. Assists in reducing impact forces
2. Helps prepare the foot for propulsion
3. It accommodates walking on uneven terrain without affecting the rearfoot
What happens to the forefoot and rearfoot in a normally functioning MTJ?
The forefoot inverts while the heel remains vertical
How is joint range of motion assessed at the MTJ?
The practitioner must stabilise the STJ and prevent any motion occurring at this joint by firmly holding the heel with one hand and holding the foot just distal to the MTJ with the other. The MTJ should then be moved in the sagittal, transverse and frontal planes. There should be most motion in the sagittal and transverse planes and minimal motion in the frontal plane
Where should most of the motion be in the MTJ?
There should be most motion in the sagittal and transverse planes and minimal motion in the frontal plane.
Which metatarsals have independent axes of motion and what planes are these ranges of motion?
The 1st and 5th metatarsals have independent axes of motion and produce triplanar motion
Which metatarsal has the least motion and why?
The second metatarsal has the least motion because it is firmly anchored to the intermediate cuneiform
Which metatarsal has the least amount of motion, the third or fourth?
The third metatarsal
What planes of motion do the 2nd, 3rd and 4th metatarsals move in?
The sagittal plane
Why is it important that the first metatarsal should be able to plantarflex?
So that the medial side of the foot makes ground contact during gait and the 1st MTPJ can dorsiflex during propulsion
What is the normal number of mm you would find when dorsiflexing and plantarflexing the first ray?
10mm in either direction
What is the term used when there is lack of plantarflexion at the first ray?
Metatarsus primus elevatus
What is metatarsus primus elevatus?
Lack of plantarflexion at the first ray
What is a short first metatarsal associated with?
Development of hallux valgus
What is a long metatarsal associated with?
Hallux rigidus
What 3 conditions does shortening of a lesser metatarsal cause?
1. Intractable plantar keratosis
2. Metatarsalgia
3. Hammer toe deformity
What happens to the 1st and 5th metatarsals in a normal position when they are moved?
They exhibit equal motion above and below the 2nd and 4th metatarsal of 10-20mm(5-10mm in each direction)
What problems does metatarsus primus elevatus cause and what is its differential diagnosis
Reduces ability of first metatarsal to bear weight and overloads central (dorsiflexed 1st metatarsal) metatarsals. DDx is forefoot varus. Shows limited plantarflexion and cannot be reduced below level of 2nd metatarsal
What is the differential diagnosis for metatarsus primus elevatus?
Forefoot varus
What does a flexible plantarflexed first metatarsal look like?
The first metatarsal may appear pronounced on the plantar surface of the foot with a cleft between the 1st and 2nd metatarsal heads. Most of the movement is in the plantar direction. Loading the metatarsal head produces reduction of the position
What does a rigid plantarflexed first metatarsal look like?
The first metatarsal cannot be reduced at all from its plantarflexed position. The forefoot tends to rotate in inversion during weightbearing and this affects rearfoot function
Where are the MTPJs?
They are the joints between the metatarsals and the proximal phalanges
What motion do the MTPJs produce?
Sagittal plane motion
What must happen at the MTPJs to facilitate toe-off?
Dorsiflexion
What degrees of dorsiflexion and plantarflexion should the first MTPJ have?
70-90 degrees dorsiflexion and 20 degrees plantarflexion
What accounts for at least 15 degrees of dorsiflexion of the MTPJ at rest?
The declined angle of the first ray
How many degrees dorsiflexion does the declined angle of the first ray give the 1st MTPJ at rest?
At least 15 degrees
What is another term for trigger toe?
Hallux extensus
What is another term for hallux extensus?
Trigger toe
What sort of foot is hallux extensus (trigger toe) associated with?
Pes cavus
What does a hallux extensis (trigger toe) look like?
It is where the proximal phalanx is abnormally dorsiflexed
What is the term used where the proximal phalanx is abnormally dorsiflexed?
Hallux extensus or trigger toe
What two pathologies can cause restriction of the movement of the MTPJs?
1. Osteophytes
2. Loose bodies or articular damage eg osteochondritis dissecans
What are two effects of Freiberg's disease?
1. Enlargement of the metatarsal head
2. Early osteoarthritis changes
Usually affects the 2nd or 3rd metatarsal
What 7 features should be assessed when looking at the alignment of the leg and foot?
1. Presence of genu varum/valgum
2. Malleolar torsion
3. Rearfoot to forefoot alignment
4. Arch height
5. Metatarsal formula
6. Toe position
7. Foot length
How do you assess the presence of lower limb varus or valgus?
The patient lies supine with the knees extended. The practitioner takes hold of the ankles and brings the legs together. If there is a difference of more than 5cm between the knees genu varum is suspected. If it is impossible to bring the malleoli together a genu valgum is present. Obesity may prevent the knees and malleoli being brought together
What two features can torsion of the leg affect?
1. In/out toeing
2. The position of the patellae
How can tibial torsion be tested?
By assessing the relationship of the tibia and fibula malleoli to each other.
How is malleolar torsion assessed?
The patient lies supine with the legs extended on the couch. The femoral condyles should be parallel to the couch. The practitioner bends down until her eyes are level with the malleoli and observes the relationship of the malleoli to each other. Place the thumb of each hand anterior to the malleoli. The medial malleoli should be one thumb's thickness anterior to the lateral malleoli
In a normal forefoot to rearfoot position what should happen?
The plantar plane of the forefoot should be parallel to the plantar plane of the rearfoot.
What 4 conditions can an inverted forefoot be due to?
1. True forefoot varus
2. Forefoot supinatus
3. Dorsiflexed 1st ray (fixed/flexible)
4. Plantarflexed 5th ray (fixed/flexible)
What does the presence of a true forefoot varus lead to?
A very flat foot with no longitudinal arch
What is forefoot supinatus?
It is an acquired soft tissue deformity due to abnormal pronation of the rearfoot. The forefoot is held in an inverted position because of soft tissue contraction
How can a forefoot supinatus and forefoot varus be differentiated?
Get the patient to stand. The foot is put into neutral. With both conditions the medial side of the foot should not be in ground contact. Pressure is applied to the dorsum of the first ray. With a supinatus there should be some give and the first ray should plantarflex. With forefoot varus any pressure on the dorsum of the first ray should cause the foot to tilt inwards and the fifth ray to leave ground contact
What three conditions may a forefoot valgus be due to?
1. Forefoot valgus
2. Plantarflexed first ray (fixed/flexible)
3. Dorsiflexed 5th ray (fixed/flexible)
What is more common, plantarflexed 1st ray and metatarsus primus elevatus or forefoot varus or forefoot valgus?
Plantarflexed first ray and metatarsus primus elevatus
What does the foot look like non weightbearing in metatarsus adductus?
The lateral border of the foot is banana-shaped
Which is usually the longest and the shortest metatarsal?
The second metatarsal is the longest and the shortest is the 5th metatarsal
What are two typical metatarsal formulae?
2>1>3>4>5 or 2>3>1>4>5
Why is it important that the 1st metatarsal is shorter than the 2nd metatarsal?
To allow normal function during propulsion. When the 1st MTPJ dorsiflexes the first ray plantarflexes on to the sesamoids. If the first metatarsal is as long as the second this cannot occur and as a result the 1st MTPJ is not able to dorsiflex resulting in overloading of the other metatarsal heads commonly the second
How much does foot length and width increase when weightbearing?
It can increase up to 1 and a half shoe size
If a foot increases by 2-3 shoe sizes weight bearing what would this indicate?
It would indicate a mobile foot which excessively pronates during gait
If a foot did not increase in size at all during weightbearing what would this indicate?
It would indicate a rigid foot
What 9 features should be looked at during a static weightbearing examination of stance?
1. Head
2. Shoulder
3. Spine
4. Pelvis
5. Angle and base of gait
6. Relaxed and neutral calcaneal stance position
7. Longitudinal arch
8. Toes
9. Foot width and length
How can you tell the difference between a true scoliosis and a functional scoliosis?
Ask the patient to bend forward. If the spine is still deviated when the hips are flexed a true scoliosis exists. If vertebrae alignment improves it is likely to be a functional scoliosis.
What is a normal angle and base of gait?
It is when the feet are slightly abducted (c 13 degrees from the midline of the body) and the distance between the malleoli is c 5cm
What is frontal plane deformity of the legs?
Genu valgum or genu varum
When will the gap between the malleoli greater, genu valgum or genu varum?
Genu valgum
When will the gap between the malleoli be lesser, genu valgum or genu varum?
Genu varum
What two conditions can excessive internal torsion lead to?
1. An adducted base of gait
2. Squinting patellae
What condition can excessive external rotation lead to?
An abducted base of gait
What is an indicator of STJ motion when weightbearing?
Relaxed calcaneal position
What does relaxed calcaneal position indicate?
STJ motion when weightbearing
What are the normal limits seen between RCSP and NCSP?
0-4 degrees
What does 0-4 degrees signify between RCSP and NCSP?
Normal limits
What does 0-4 degrees signify between RCSP and NCSP?
Normal limits
What does 4-7 degrees signify between RCSP and NCSP?
Moderate pronation requiring treatment if symptomatic or a cause for concern
What would 8 degrees or above between RCSP and NCSP signify?
Marked pronation
What are four causes of an abnormal everted RCSP
1. Compensated forefoot varus
2. Compensated ankle equinus
3. Tibial valgum/varum
4. Internal/external torsion of the leg
If the calcaneus is not everted during RCSP what could this indicate?
If the calcaneus is not everted it does not mean that abnormal pronation is not occurring. Compensation for a rearfoot varus involves excessive STJ pronation in order to bring the medial tubercle of the heel into ground contact and provide shock absorption during contact phase of gait. A 10 degree rearfoot varus will require 10 degrees of pronation in order to bring the heel into a vertical position. Although excessive pronation has occurred, the RCSP will appear vertical and not everted.
What could be five causes of an inverted RCSP?
1. Neurological problem
2. An uncompensated varus deformity affecting the rear or forefoot,
3. Subtalar joint damage
4. Tonic spasm of the inverters of the foot
5. Presence of a plantarflexed first ray
What does NCSP and RCSP measure?
It only measures frontal plane motion (inversion/eversion)
What four factors affect the shape of the longitudinal arch?
1. The rearfoot/forefoot position
2. The declination angles of the metatarsals
3. The inclination angle of the calcaneus
4. The tone and activity of intrinsic and extrinsic muscles
What is a good test of longitudinal arch height?
Asking the patient to stand on tiptoe and the position of the foot arch should be noted. With rigid flat feet the arch height does not increase when the patient stands on tip toe. With a flexible flat foot the arch height increases.
What two conditions can cause rigid flat feet?
1. Bony coalitions (synostoses)
2. Contractures due to muscle imbalance or neurological paralysis with subsequent soft tissue contractures
What are the three main causes of lesser toe deformities (lesser hammer toe syndrome)?
1. Flexor stabilisation
2. Flexor substitution
3. Extensor substitution
What does the foot look like when there is flexor stabilisation?
A contraction (hammering) of all the lesser toes with an associated adductovarus deformity of the 5th and sometimes 4 toes (quadratus plantae losing its mechanical advantage)
When does flexor stabilisation occur and what muscles in the foot are involved?
Flexor stabilisation can occur in an excessively pronated foot during late stance phase when flexor digitorum longus and/or flexor digitorum brevis have gained mechanical advantage over the interossei muscles.
Why does flexor stabilisation occur and what muscles are involved?
Pronation of the STJ allows unlocking of the midtarsal joint resulting in forefoot hypermobility. The flexors fire earlier and longer than normal in an attempt to stabilise the forefoot. These muscles are ineffective at stabilising the forefoot but effective in overpowering the small interosseous muscles causing hammering or clawing of the toes.
What is flexor substitution?
A straight contraction of all the lesser toes with no adductovarus of the fourth and fifth toes.
When does flexor substitution occur and what muscles are involved?
This can occur in a supinated foot during late stance phase when the flexors have gained mechanical advantage over the interossei muscles.
Why does flexor substitution occur and what muscles are involved?
It occurs when the triceps surae muscle is weak and the deep posterior and lateral leg muscles try to substitute for the weak triceps.
Which is the least common of the 3 pathologies that create lesser toe deformities?
Flexor substitution
What is extensor substitution?
It describes the excessive dorsiflexion of the toes during swing phase of gait and at heel strike
What muscles are involved in extensor substitution?
Extensor digitorum longus gains mechanical advantage over the lumbricales. Without the stabilising effect of the lumbricales the MTPJs will be excessively dorsiflexed resulting in severe dorsal contraction of the toes. This deformity often begins as a flexible deformity that may reduce completely during weightbearing but becomes more rigid as accommodative contractures develop
What four factors can cause extensor substitution?
1. Anterior pes cavus
2. Ankle equinus
3. Pain
4. Spasticity of the extensor digitorum longus muscle or weakness of the lumbricales.
How many degrees is considered normal for abduction of the hallux?
15 degrees
What is another term for tailor's bunion?
Digiti quinti varus
What is hallux abductus?
Hallux abducted more than 15 degrees from the midline of the body
What is the term for a hallux abducted more than 15 degrees from the midline of the body?
Hallux abductus
What is hallux abductovalgus?
Hallux abducted more than 15 degrees from the midline of the body and the hallux is also rotated so that the hallux nail faces towards the midline of the body
What is the term for Hallux abducted more than 15 degrees from the midline of the body and the hallux is also rotated so that the hallux nail faces towards the midline of the body?
Hallux abductovalgus
What is hallux abductus interphalangeus?
Distal hallucal phalanx abducted away from the midline of the body
What is the term for a distal hallucal phalanx abducted away from the midline of the body?
Hallux abductus interphalangeus
What is hallux varus?
Hallux adducted towards the midline of the body
What is the term for a hallux adducted towards the midline of the body?
Hallux varus
What is hallux limitus?
Reduced dorsiflexion at the 1st MTPJ
What is the term used for reduced dorsiflexion at the 1st MTPJ
Hallux limitus
What is hallux rigidus?
Complete lack of dorsiflexion at the 1st MTPJ
What is complete lack of dorsiflexion at the 1st MTPJ?
Hallux rigidus
What is hallux flexus
Plantarflexion of the hallux at the 1st MTPJ
What is the term for plantarflexion of the hallux at the 1st MTPJ?
Hallux flexus
What is hallux extensus?
Dorsiflexion of the hallux at the 1st MTPJ
What is the term for dorsiflexion of the hallux at the 1st MTPJ?
Hallux extensus
What is a hyperextended hallux?
Distal phalanx of the hallux dorsiflexed
What is the term for distal phalanx of the hallux dorsiflexed?
Hyperextended hallux
What is a hammer toe?
Dorsiflexion at the MTPJ, plantarflexion at the proximal IPJ and either normal position or dorsiflexion at the distal IPJ
What is the term for dorsiflexion at the MTPJ, plantarflexion at the proximal IPJ and either normal position or dorsiflexion at the distal IPJ?
Hammer toe
What is a claw toe?
Dorsiflexion at the MTPJ, plantarflexion at the proximal and distal IPJs
What is the term for dorsiflexion at the MTPJ, plantarflexion at the proximal and distal IPJs?
A claw toe
What is a retracted toe?
A claw toe where the apex of the toe is not in ground contact
What is a claw toe where the apex of the toe is not in ground contact?
A retracted toe
What is a mallet toe?
Plantarflexion at the distal IPJ
What is the term for plantarflexion at the distal IPJ?
A mallet toe
What is an adductovarus fifth?
Fifth toe rotated so that nail is facing away from the midline of the body and the toe is adducted (moved towards the midline of the body)
What is the term for a fifth toe rotated so that nail is facing away from the midline of the body and the toe is adducted (moved towards the midline of the body)?
Adductovarus fifth
What is it when toes are dorsally displaced?
One or more toes is in a dorsiflexed position in comparison to the other toes
What is the term for one or more toes is in a dorsiflexed position in comparison to the other toes?
Dorsally displaced
What is a real limb length discrepancy due to and what can cause a LLI?
It can be due to a difference in the length of the femurs or tibiae and is common after a hip replacement
What two factors can cause an apparent limb length discrepancy?
1. Osteoarthritis
2. Scoliosis
What 7 factors can reveal the presence of a limb length discrepancy?
1. Shoulder tilt to one side
2. Unequal arm swing
3. Pelvic tilt
4. Foot supinated on the short side
5. Foot pronated on the long side
6. Knee flexed on the long side
7. Ankle plantarflexed on the short side
How do you assess for the presence of a real limb length discrepancy?
The patient lies supine on a flat couch. The practitioner places her hands around the heels and asks the patient to push their buttocks off the couch and then replace them. The practitioner exerts a slight pull on the legs at the same time bringing the legs together so that the knees and malleoli are touching. The knees and malleoli should be level. A difference indicates an inequality at the femur or tibia. To identify which bone is affected the knees should be flexed and the heels pushed flush against the buttocks (Skyline/Allis test). If the tibiae are of unequal length, the knees or tibial tubercles will be at different levels. If one femur is longer than the other, the knee of the longer femur will be positioned further forward than the other knee.
What is the skyline/allis test?
It should show which bone is affected if there is a limb length discrepancy
How do you do a skyline/allis test?
The knees should be flexed and the heels pushed flush against the buttocks
When using a tape measure to measure limb length discrepancy where should it be placed?
At the anterior superior iliac spine (ASIS) to the medial malleolus
How can the distinction between a real or apparent LLI be achieved non-weightbearing?
The tape is placed at the xiphisternum and the distance from the xiphisternum to each malleolus is measured. If the values are the same then the LLI is likely to be apparent where the cause could be at the hip or pelvis where a fixed deformity makes the limbs appear unequal.
How can the distinction between a real or apparent LLI be achieved weightbearing?
1. The patient stands in the RCSP
2. The position of the ASISs is assessed to see if they are level
3. The feet are then placed in the NCSP
4. The position of the ASISs is assessed to see if they are level
5. If the ASISs are not level in either the RCSP and NCSP and the extent of the discrepancy remains the same in RCSP and NCSP a true LLI should be suspected. If the ASISs are on the same level in the NCSP but differ for the RCSP an apparent LLI should be suspected
What is the name for the organ of skin?
The integument
What are the four ways that skin disorders affect individuals?
1. Discomfort ie itching and pain
2. Disability ie foot ulceration, hand eczema
3. Disfigurement ie scarring or rashes
4. Death ie skin cancers
What two factors can cause clubbing of the nails?
1. Smoking
2. Lung disease
What are the five most common disorders that affect the lower limb?
1. Fungal and other skin infections
2. Dermatitis/eczema
3. Psoriasis
4. Warts
5. Tumours (benign and malignant)
How many layers are there in the skin and what are they?
1. Epithelium (epidermis)
2. Dermis (connective tissue matrix firmly bound together at the dermo-epidermal junction)
3. Subcutaneous (fat) layer
What are the seven functions of the skin?
1. Physical barrier ie thermal/mechanical/radiation
2. Chemical barrier ie irritants/allergens/water loss
3. Microbiological barrier ie infections/infestations
4. Touch/vibration/pressure/temperature
5. Nociception
6. Thermoregulation and assistance in maintaining blood pressure
7. Vitamin D and cholesterol production
What is the epidermis?
An avascular structure relying on the diffusion of materials across the dermo-epidermal junction for nutrients and waste disposal
What is the epidermis composed of?
It is principally composed of keratinocytes (corneocytes) which make up 80% of the cells as well as melanocytes, Merkel's discs and Langerhan's cells.
What are the three appendages in the epidermis?
1. Nails
2. Sweat glands
3. Sebaceous glands
How thick is the epidermis?
From 0.4 to 1.5mm depending on the anatomiccal location
How many layers are there in the epidermis and what are they?
Four layers
1. Basal layer (stratum germinativum)
2. Prickle cell layer (stratum spinosum)
3. Granular layer (stratum granulosum)
4. Horny layer (stratum corneum)
What are Merkel's discs?
Mechanoreceptors in the skin
What are mechanoreceptors in the skin called?
Merkel's discs
What are Langerhans cells?
They are dendritic cells which take up and process microbial antigens to become an antigen presenting cell when infection takes place in the skin
What does the basal layer (stratus germinativum) consist of?
The basal layer consists of a single undulating layer of cuboidal keratinocytes
What is the basal layer attached to?
The cells in this layer are attached to the dermo-epidermal junction (DEJ) by tonofilaments.
What is the function of cells in the basal layer?
They generate cells of the more superficial layers of the epidermis
Where are melanocytes located?
In the basal layer
What specialist cells are located in the basal layer?
Melanocytes
What is the ratio of melanocytes in the skin?
In sun-exposed skin they may have a ratio of 1 to 4 but in unexposed areas such as the surface of the foot they may decrease to 1 in 30
What are melanocytes?
They are dendritic cells which produce a pigment melanin in specialist organelles known as melanosomes
How does melanin work?
It forms a protective cap over the cell nucleus, its function being to limit the amount of harmful ultraviolet radiation reaching the DNA within the nucleus and it also may have a role in mopping up free radicals which arise as a result of inflammation within the skin
What is the function of Merkel's cells?
The perception of light touch
Where in the body are Merkel's cells predominantly found
They are numerous on the volar (pulp) surfaces of the fingers and toes, in the nail beds and the dorsum of the foot
Where do the new cells generated by the basal layer go to?
The prickle cell layer (stratum spinosum)
What do the cells look like in the prickle cell layer (stratum spinosum)?
They are more polyhedral and they have abundant spinous processes called desmosomes which bond adjacent cells together. They are an important component of the epidermis as they resist mechanical stress.
Which layer of the epidermis are Langerhans cells in?
The prickle cell layer (stratum spinosum)
What cells that are immunological in function are found in the prickle cell layer (stratum spinosum)?
Langerhans cells
What do cells look like when they have reached the granular layer (stratum granulosum)?
They are much more flattened and are packed with keratohyalin granules which are composed of proteins and various types of keratin
What is the primary function of the granular layer (stratum granulosum)?
At the junction of stratum corneum a watertight seal or hydrophobic barrier is formed along the junction of the granular layer (stratum granulosum) and stratum corneum. In eczematous plaques this process of a watertight barrier is often reduced leading to increased water loss through the epidermis and resultant fissuring.
What is thought to cause the water loss and resulting fissuring of eczematous plaques?
The lack of formation of a hydrophobic barrier between stratum corneum and stratum granulosum (granular layer)
What happens to the cell when it reaches the horny layer (stratum corneum)?
The cells lose a percentage of their water content and have a very flattened appearance with around 15-20 layers of keratinocytes. The remaining intracellular water accumulates and causes the cell to swell which improves the barrier seal to the epidermis and prevents fissuring of the skin under normal tensile forces.
How long does it take for a keratinocyte to ascend through the four layers?
28-70 days
How quickly does a cell ascend through the four layers when the patient has psoriasis?
As little as 5 days
What is the term for when the dermis meets the epidermis?
The dermo-epidermal juntion (DEJ)
What is the dermo-epidermal junction (DEJ)?
Where the dermis meets the epidermis
What are dermal papillae?
It is where the dermis makes regular finger-like folds into the overlying epidermis
What is the term for where the dermis makes regular finger-like folds into the overlying epidermis
Dermal papillae
How is the dermo-epidermal junction constructed and what is it made up of?
It is a basement membrane divided into a number of layers crossed by a complex of filaments, keratins and proteins that form an anchoring surface between the dermis and epidermis
What are the protrusions from the epidermis into the dermis called?
Rete pegs or epidermal ridges
What are rete pegs or epidermal ridges?
Protrusions from the epidermis into the dermis
What is a major dermatological feature of the plantar surface of the foot?
Dermal papillae and rete pegs or epidermal ridges where mechanical stresses are high
Is the DEJ (dermo-epidermal junction) prone to many pathologies and what are they?
The DEJ is the site of many pathologies and this can lead to loss of adhesion and the development of blistering diseases eg epidermolysis bullosa, dermatitis herpetiformis
What two pathologies are associated with the DEJ (dermo-epidermal junction)?
1. Epidermolysis bullosa
2. Dermatitis herpetiformis
What lies below the DEJ (dermo-epidermal junction)?
The dermis
What does the dermis consist of?
Dense fibro-elastic connective tissues in a gel-like base (ground substance) which contains glycosaminoglycans.
What five appendages are found in the dermis?
1. Skin appendages eg hair follicles, sebaceous glands, sweat glands
2. Macrophages
3. Fibroblasts
4. Neurovascular network
5. T lymphocytes and mast cells
How many layers are there in the dermis and what are they?
There are two
1. The thin upper layer or papillary dermis
2. The less vascular, deep reticular layer
What does the thin upper layer of the dermis contain?
The blood and lymphatic vessels
What does the less vascular deep reticular layer of the dermis contain?
Collagen and elastic fibres
What is collagen's role within the dermis?
Collagen strands provide tensile strength with elasticity afforded by interwoven elastic fibres that make this a pliable tissue
What separates the dermis from the fascia?
The subcutaneous (fat) layer
Where is the subcutaneous (fat) layer found?
Between the dermis and the fascia
What is found in the subcutaneous (fat) layer?
It is a layer of fat cells rich in nerves, blood vessels and lymphatics
What is the function of the subcutaneous (fat) layer?
Its main function is to provide thermal insulation and physical protection
Which layer of skin provides thermal insulation and physical protection?
Subcutaneous (fat) layer
Where is the subcutaneous (fat) layer particularly well developed in the foot?
Across the metatarsal heads and heels where it may be up to 18mm thick
How is the plantar fat constructed under the fascia?
Plantar fat is divided into vertical chambers by dividing fibrous septae which act as an effective shock absorption system
Where does the main blood supply to the skin arise from?
A network (or plexus) of vessels located in the subcutaneous layer
What does the blood supply at the level of the subcutaneous layer?
Branches supply eccrine sweat glands located deep in the reticular dermis
Where are eccrine sweat glands located?
Deep in the reticular dermis
Where is the second network of vessels located after the subcutaneous layer?
In the mid-dermis
What do vessels supply in the mid-dermis?
Hair follicles
What part of the dermis are hair follicles found in?
In the mid-dermis
Where is the third network of blood vessels in the dermis?
In the papillary dermis
Where are the most densely organised network of capillaries found in the human body?
The plantar surface of the foot
What part of the skin are the lymph vessels found?
In the dermis
What is one of the functions of lymph vessels in the skin?
One of the functions is maintaining turgidity which is vital to retaining mechanical resilience in the skin requiring a fine balance between supply and drainage as dehydration and oedema can lead to a reduction in skin stiffness and deformation in the structure of collagen and elastic fibres
What two conditions leads to a reduction in skin stiffness and deformation in the structure of collagen and elastic fibres?
1. Dehydration
2. Oedema
What problems can dehydration and oedema cause in skin?
Dehydration and oedema can lead to a reduction in skin stiffness and deformation in the structure of collagen and elastic fibres
Where are hair follicles not found?
The plantar surface of the foot
Where are few sebaceous glands found?
The plantar surface of the foot
What are the two types of sweat glands and where are they found?
1. Apocrine glands which are larger and exclusively associated with the hair follicle in the groin and axillae
2. The smaller eccrine gland is a smaller coiled structure located in the reticular dermis with an opening directly onto the epidermis
What does the eccrine gland look like and where is it located?
It is a smal coiled structure located in the reticular dermis with an opening directly onto the epidermis
What stimulates sweat glands?
The sympathetic branch of the autonomic system
Where are sweat glands most numerous?
They are most numerous on the plantar surfaces of the feet
What are the two functions of sweating?
1. Thermoregulation
2. Aid gripping
How is gripping further enhanced in the hands and soles of the feet?
By the presence of dermatoglyphics which are a result of the unique arrangement of collagen fibres in the dermis and are more prominent on the weightbearing surfaces of the foot (pulp of the toes, heel and metatarsal area)
What protects the integrity of the foot?
A dense and highly organised neural network in the underlying dermis which provides a rich tactile perception necessary to protect the integrity of the foot
What skin problems can stress make worse?
1. Psoriasis
2. Eczema
3. Lichen planus
What external factor can make psoriasis, lichen planus and eczema worse?
Stress
What skin condition is improved by sunlight?
Psoriasis
What condition is made worse by sunlight?
Lupus erythematosus
What external factor improves psoriasis?
Sunlight
What external factor makes lupus erythematosus worse?
Sunlight
What medication can dramatically increase the spread of a fungal eruption?
A steroid cream
What is dermatitis herpetiformis?
A blistering disorder
What other condition is dermatitis herpetiformis also associated with?
Coeliac disease
What is coeliac disease?
A gluten intolerance affecting the gut
What condition is more associated with outdoor workers?
Skin cancer
What occupational group is skin cancer more associated with?
Outdoor workers
What external condition can make psoriasis worse?
Alcoholic consumption
Which racial group is more predisposed to melanoma?
Caucasians
What skin condition are Caucasians more likely to get?
Melanoma
What are the nine areas of the skin affected in aging?
1. It appears more translucent
2. Irregular pigmentation
3. Thinning of the skin occurs at all layers including the subcutaneous layer which may be evident on the plantar area of the foot
4. Natural turgidity and elasticity is lost
5. Pinching of the skin results in “tenting” as the skin fails to return to its natural shape
6. Decreased sweat and sebum production leading to the normal skin surface barrier becoming compromised so more prone to the effects of drying and irritation
7. A reduced immune response as the numbers of T and B lymphocytes along with Langerhans’ cells decrease leaving the skin more open to infection and malignant change
8. Any inflammation that does occur tends to be damped down so signs of inflammation appear less acute
9. Nails reduce their rate of growth, become thicker and slightly yellow in colour
What skin condition can dandruff mimic?
Psoriasis
What skin condition can look like scalp psoriasis?
Dandruff
What surfaces of the arms and legs does eczema affect?
The flexor surfaces
What is the distribution pattern of atopic eczema?
Antecubital and popliteal fossa, face, neck and hands
What does antecubital mean?
The anterior part of the elbow
What is the term for the anterior part of the elbow?
Antecubital
What is the distribution pattern for contact dermatitis?
Hands, face and feet
What is the distribution pattern for psoriasis?
Extensor surfaces of knees and elbows, scalp, back, nails
What is the distribution pattern for lichen planus?
Flexor surfaces of wrist, ankles, oral cavity and genitalia
What is the distribution pattern of erythema nodosum?
The anterior surfaces of shins
What does annular mean when describing a skin condition?
Ring-like
What 3 skin conditions have annular (ring-like) lesions?
1. Psoriasis
2. Lichen planus
3. Granuloma annulare
What sort of lesions do psoriasis, lichen planus and granuloma annulare have?
Annular (ring-like) lesions
What does nummular mean?
Round or coin-like
What skin condition has nummular (round or coin-like) conditions?
Nummular eczema
What sort of lesion does nummular eczema have?
Nummular (round or coin-like)
What 2 conditions have discoid lesions?
1. Eczema
2. Psoriasis
What sort of lesions do eczema or psoriasis have?
Discoid lesions
What is a reticulate lesion?
A lesion that looks net-like
What sort of lesions does livedo reticularis have?
A reticular (net-like) lesion
What skin condition has a reticular (net-like) lesion?
Livedo reticularis
What is livedo reticularis?
Livedo reticularis refers to a condition in which dilation of capillary blood vessels and stagnation of blood within these vessels causes mottled discolouration of the skin. It is described as being reticular (net-like) cyanotic, cutaneous discolouration surrounding pale central areas. It occurs mostly on the legs, arms and trunk and is more pronounced in cold weather.
What does an arcuate lesion look like?
Curved
What skin condition presents with arcuate (curved) lesions?
Contact dermatitis
What sort of lesions does contact dermatitis present with?
Arcuate (curved) lesions
What 2 conditions present with grouped lesions?
1. Insect bites
2. Dermatitis herpetiformis
What sort of lesions do insect bites and dermatitis herpetiformis present with?
Grouped lesions
What is Koebner’s phenomenon?
It is where skin lesions of a specific disease may appear at a site of trauma which was previously unaffected.
What are four examples of Koebner’s phenomena?
1. Warts
2. Psoriasis
3. Lichen planus
4. Molluscum contagiosum
What is molluscum contagiosum?
It is a viral infection of the skin or occasionally of the mucous membranes
What is the DDX between fungal infections and psoriasis and eczema?
Psoriasis and fungal infections have much more marked, well-defined edges than eczema
How can you tell if a rash or lesion is due to blood?
the colour is pink, purple or red and if gentle pressure blanches the area
If the area of skin does not blanch what 2 conditions may this be due to?
Extravasation (loss of blood constituents into the skin) or pigmentation due to melanin
What is extravasation?
Loss of blood constituents into the skin
What three micro-organisms are malodorous?
1. Pseudomonas
2. Staphylococcus
3. Diphtheroids
What is bromhidrosis?
Excessive sweating
What is the term for excessive sweating?
Bromhidrosis
How may skin lesions be classified and what do these classifications mean?
Primary and secondary. Primary lesions arise due to the initial effects of a condition. Secondary lesions evolve from or as a complication of primary lesions
What happens to psoriatic skin when it is scratched?
It demonstrates pinpoint bleeding and the scaling becomes more pronounced.
What is Auspitz sign?
Auspitz's sign is the appearance of punctate bleeding spots when psoriasis scales are scraped off
What is the medical term for psoriatic skin that gives the appearance of punctate bleeding spots when psoriasis scales are scraped off?
Auspitz sign
What are the three things that skin does when it is injured or infected?
1. It bleeds
2. Oozes serum
3. Discharges pus
What is a common feature in eczema?
Crusting
What is erythema?
Redness, often due to inflammatory response
What is the term used for redness often due to inflammatory response?
Erythema
What is a macule?
It is flat, differently coloured eg freckles, vitiligo
What is vitiligo?
Vitiligo or leukoderma is a chronic skin disorder that causes loss of pigment, resulting in irregular pale patches of skin.
What is the medical description for flat, differently coloured patches of skin such as freckles or vitiligo?
Macules
What is a papule?
It is a palpable, solid bump in the skin eg lichen planus
What is lichen planus?
Lichen planus is a chronic mucocutaneous disease that affects the skin and the oral mucosa, and presents itself in the form of papules, lesions or rashes.
What is the medical term describing a palpable, solid bump in the skin as in lichen planus?
A papule
What is a nodule?
It is a palpable, deeper mass than a papule eg ganglion or rheumatoid nodule
What is the medical description for palpable, deeper mass than a papule such as seen in a ganglion or rheumatoid nodule?
A nodule
What is a plaque?
It is an elevated, disc-shaped area of skn over 1cm in diameter eg psoriasis
What is the medical term for an elevated, disc-shaped area of skin over 1cm in diameter as seen in psoriasis?
A plaque
What does a tumour look like?
It is a large mass over 2cm in diameter eg lipoma
What is the medical term describing a large mass over 2cm in diameter such as a lipoma
A tumour
What is a cyst?
It is a subdermal, fluid-filled fibrous swelling, loosely attached to deeper structures eg dermal cyst
What is the medical term describing a subdermal, fluid-filled fibrous swelling, loosely attached to deeper structures?
A cyst
What is a weal?
Large oedematous bump eg insect bite
What is the medical term describing a large oedematous bump such as seen in an insect bite?
A weal
What is a vesicle?
A tiny, pinprick-sized collection of fluid eg mycosis, pompholyx
What is the medical term describing a tiny, pinprick-sized collection of fluid such as seen in mycosis or pompholyx?
A vesicle
What is pompholyx?
Pompholyx is a common type of eczema affecting the hands and sometimes the feet (pedopompholyx). It is also known as dyshidrotic eczema or vesicular eczema of the hands and/or feet.
What is bulla?
It is serous fluid/blood-filled intraepidermal or dermoepidermal sac eg bullous pemphigoid
What is the medical term for a serous fluid/blood-filled intraepidermal or dermoepidermal sac?
Bulla
What is bullous pemphigoid?
Bullous pemphigoid is a blistering skin disease which usually affects middle aged or elderly persons. It is an immunobullous disease, i.e. the blisters are due an immune reaction within the skin.
What is a pustule?
It is a vesicle or bulla filled with pus eg acne, pustular psoriasis
What is the medical term for a vesicle or bulla filled with pus?
A pustule
What is a burrow?
A short, linear mark in skin visible with magnifying lens eg scabies
What is the medical term for a short, linear mark in skin visible with magnifying lens eg scabies?
A burrow
What is scabies?
Scabies is an itchy rash caused by a little mite that burrows in the skin surface
What is an itchy rash caused by a little mite that burrows in the skin surface?
Scabies
What is ecchymosis?
Large extravasation of blood into the tissues eg bruising
What is the medical terms for large extravasation of blood into the tissues?
Ecchymosis
What is petechia?
Pinhead-sized macule caused by blood seeping into the skin
What is the medical term for a pinhead-sized macule caused by blood seeping into the skin?
Petechia
What is telangiectasiae?
Permanently dilated small cutaneous blood vessels
What is the medical term for permanently dilated small cutaneous blood vessels?
Telangiectasiae
What happens to keratin when shedding fails?
It forms thickened areas
What is the medical term for warty?
Papillomatous
What does papillomatous mean?
Warty
What happens during lichenification?
It is a reaction of the skin to chronic rubbing or scratching and involves the whole epidermis
What is the medical term for the reaction of the skin to chronic rubbing or scratching and involves the whole epidermis?
Lichenification
What is a common feature of atopic eczema and where does it appear?
Lichenification and it appears on the flexures.
What are flexures?
The areas where the limbs bend, bringing together two surfaces, for example, the front of the elbows and the back of the knees
What is the medical term for the areas where the limbs bend, bringing together two surfaces, for example, the front of the elbows and the back of the knees?
Flexures
What does excoriation mean?
Scratch
What is the medical term for scratch?
Excoriation
What is an ulcer?
It is an area of full thickness skin loss usually covered by exudate or crust
What is an area of full thickness skin loss usually covered by exudate or crust?
An ulcer
What does atrophic skin look like?
The skin is depressed and blood vessels are visible beneath. The skin is often pale and wrinkled.
How would you describe skin that is depressed and blood vessels are visible beneath as well as being pale and wrinkled?
Atrophic
What are large pustules called?
Abscesses
How would you describe an abscess?
As a large pustule
What three other primary lesions can a scar look like?
1. Macule
2. Papule
3. Plaque
What is the primary function of the toenail?
The toenail is purely a protective plate overlying the deep structures and acting as a counter pressure to the volar tissues
How are the toenails supplied with nutrients?
Nails are provided with a rich neurovascular supply
What are the names of the 15 primary skin lesions?
1. Erythema
2. Macule
3. Papule
4. Nodule
5. Plaque
6. Tumour
7. Cyst
8. Weal
9. Vesicle
10. Bulla
11. Pustule
12. Burrow
13. Ecchymosis
14. Petechia
15. Telangiectasiae
What are the names of the 14 secondary skin lesions?
1. Scale
2. Crust
3. Excoriation
4. Fissure
5. Necrosis
6. Ulcer
7. Scar
8. Keloid
9. Striae
10. Purpura
11. Urticuria
12. Lichenification
13. Haematoma
14. Sinus
What is a scale?
A flake of skin eg mycosis, psoriasis
What is the medical term for a flake of skin as seen in mycosis and psoriasis?
A scale
What is a crust?
A scab, dried serous exudates eg acute eczema
What is the medical term for a scab or dried serous exudates as seen in acute eczema?
A crust
What is excoriation?
Scratch marks eg pruritis
What is the medical term for scratch marks as seen in pruritis?
Excoriation
What is a fissure?
It's a crack in dry or moist skin
What is the medical term for a crack in dry or moist skin?
A fissure
What is necrosis?
Non-viable tissue
What is the medical term for non-viable tissue?
Necrosis
What is an ulcer?
Loss of epidermis. It may extend through the dermis to deeper tissue eg venous ulcer
What is the medical term for loss of epidermis. It may extend through the dermis to deeper tissue?
An ulcer
What is a scar?
Fibrous tissue production post-healing
What is the medical term for fibrous tissue production post-healing?
A scar
What is a keloid?
Excessive production of fibrous tissue post-healing
What is the medical term for excessive production of fibrous tissue post-healing?
A keloid
What are striae?
Lines in skin that do not have normal skin tone eg striae tensae in pregnancy, Cushing's disease
What is the medical term for lines in skin that do not have normal skin tone?
Striae
What is purpura?
Purplish lesions which do not blanche under pressure eg Vitamin C deficiency
What is the medical term for purplish lesions which do not blanche under pressure as seen in Vitamin C deficiency?
Purpura
What is urticuria
Nettle rash eg drug eruption, allergy, heat
What is the medical term for nettle rash as seen in drug eruption, allergy and heat?
Urticuria
What is lichenification?
Patchy toughening of the skin eg chronic eczema
What is the medical term for patchy toughening of the skin as seen in chronic eczema?
Lichenification
What is a haematoma?
A blood-filled blister
What is the medical term for a blood-filled blister?
Haematoma
What is a sinus?
A channel that allows the escape of pus or fluid from tissues
What is the medical term for a channel that allows the escape of pus or fluid from tissues?
A sinus
How many widths are there in the nail plate and what are they?
1. Dorsal nail plate
2. Intermediate nail plate
3. Ventral nail plate
Where is the hyponychium?
Under the nail just before the free edge
What is the medical term for under the nail just before the free edge?
Hyponychium
Where is the eponychium?
Distal to the proximal nail fold on the dorsum of the nail
What is distal to the proximal nail fold on the dorsum of the nail?
The eponychium
How long does a toe nail take to grow out completely?
12-18 months
What is onychauxis?
Thickening of the nail plate usually due to trauma
What is the medical term for thickening of the nail plate due to trauma?
Onychauxis
What is onychogryphosis?
Thickened nail with a distortion in the direction of growth
What is the medical term for a thickened nail with a distortion in the direction of growth?
Onychogryphosis
What is onycholysis?
Separation of the nail from the nail bed, distal to proximal
What is the medical term for separation of the nail from the nail bed distally to proximally?
Onycholysis
What is onychomadesis?
Separation of the nail from the nail bed, proximal to distal
What is the medical term for separation of the nail from the nail bed proximally to distally?
Onychomadesis
What is onychocryptosis?
Ingrowing toe nail
What is the medical term for an ingrowing toe nail?
Onychocryptosis
What is involution?
An inward curvature of the lateral or medial edges of the nail plate towards the nail bed
What is the medical term for an inward curvature of the lateral or medial edges of the nail plate towards the nail bed?
Involution
What are splinter haemorrhages?
Longitudinal, plum-coloured linear haemorrhage (around 2mm in length) under the nail plate
What is the medical term for longitudinal plum-coloured linear haemorrhage (around 2mm in length) under the nail plate?
Splinter haemorrhages
What is paronychia?
It is inflammation of the tissues surrounding the nails
What is the medical term for inflammation of the tissues surrounding the nails?
Paronychia
What is onychomycosis?
Fungal infection of the nail plate
What is the medical term for fungal infection of the nail plate?
Onychomycosis
What is chromonychia?
Abnormal colouration of the nail tissue
What is the medical term for abnormal colouration of the nail tissue?
Chromonychia
What is koilonychia?
Transverse and longitudinal concave nail dystrophy which gives a spoon-shaped appearance
What is the medical term for transverse and longitudinal concave nail dystrophy which gives a spoon-shaped appearance?
Koilonychia
What is clubbing?
Increased longitudinal curvature of the nail plate with enlargement of the pulp of the digit
What is the medical term for increased longitudinal curvature of the nail plate with enlargement of the pulp of the digit?
Clubbing
What are Beau's lines?
Transverse ridging of the nail plate seen as the result of a temporary cessation of nail growth
What is the medical term for transverse ridging of the nail plate seen as the result of a temporary cessation of nail growth?
Beau's lines
What four factors can lead to an increase in the rate of growth of the nail?
1. Psoriasis
2. Hyperthyroidism
3. Nail trauma
4. Drugs
What shape are toe nails?
Quadrangular
What is a pincer nail?
Transverse over-curvature of the nail or involution
What is another term for transverse over-curvature of the nail or involution?
A pincer nail
What two things happens if there is a subungual exostosis?
1. Lifting of the distal nail plate
2. Pain
What four disorders can cause splinter haemorrhages in nails?
1. Trauma
2. Rheumatoid disease
3. Vasculitis
4, Skin disease such as psoriasis or eczema
What causes splinter haemorrhages?
Extravasation of blood between the nail bed and plate
What fourteen factors can cause koilonychia (spooning)?
1. Idiopathic
2. Hereditary
3. Iron deficiency anaemias
4. Insulin-dependent diabetes
5. Physiologically thin nails eg children
6. Psoriasis
7. Alopecia
8. Lichen planus
9. Raynaud's disease
10. Scleroderma/systemic sclerosis
11. Renal transplant
12. Thyroid disease
13. Acromegaly
14. Occupation (immersion in oils, acid and alkali)
What seven factors can cause clubbing of the nails?
1. Idiopathic
2. Hereditary
3. Lung disease
- bronchiectasis
- lung cancers
- abscess
- lung infections
- fibrotic lung disease
- emphysema
- asthma in childhood
4. Cardiovascular disease
- congestive heart failure
- subacute bacterial endocarditis
- myxoid tumours
- congenital heart disease
5. Alimentary disease
- ulcerative colitis
- Crohn's disease
- gut cancers
6. Endocrine
- active hepatitis
- auto-immune thyroidits
- acromegaly
7. Other
- polycythaemia
- cirrhosis
- malnutrition
What is scleroderma?
Scleroderma is a chronic autoimmune disease characterized by a hardening or sclerosis in the skin or other organs.
What is the name of the disease that is a chronic autoimmune disease characterized by a hardening or sclerosis in the skin or other organs?
Scleroderma
What is a myxoid tumour?
A tumour that arises from or occupies the myocardial or pericardial tissues
What is the name of a tumour that arises from or occupies the myocardial or pericardial tissues?
A myxoid tumour
What is polycythaemia?
It is a condition where there is a high red blood cell count
What is the condition called where there is a high red blood cell count?
Polycythaemia
What 3 conditions accentuate longitudinal lines in nails?
1. RA
2. PVD
3. Lichen planus
Define metatarsus adductus
Metatarsus adductus is a transverse plane deformity arising at the tarsometatarsal (Lisfranc) joint
What is the key fact to establish about a metatarsus adductus foot?
Whether the deformity is flexible.
What percentage of metatarsus adductus deformities spontaneously resolve?
90%