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44 Cards in this Set
- Front
- Back
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what is a macrocyte?
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RBC > 8 micrometer in diameter
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what is hemoglobin S
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HbS (S=sickle) is the abnormal variant of hemoglobin A, which occurs in sickle-red blood cells
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Two coagulation tests excluding BT and PTT
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-Platelet count
-coagulation time -fibrinogen, -thromboplastin time |
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tests done in hematology excluding CBC, ESR and coagulation
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-sickle cell test
-LE cell -eosinophil count -hemoglobin electrophoresis -leukocyte alkaline phosphatade |
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one thrombin sensitive coagulation factor
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-fibrinogen factor 1, 5, 8, 13
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one disease in which ESR is high
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-rheumatoid arthritis
-SLE -MI -Lyme |
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disease in which normoblastosis is seen
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-pernicious anemia
-folic acid deficiency |
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disease in which PLT functionis affected
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Bernard-soulier syndrome
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3 characteristics of an immature blood cell
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-big size
-big, round, oval, or slightly indented nucleus and relatively large in relation to the cytoplasm -blue cytoplasm (high amount of RNA w/ affinity for blue dyes) -red nuclear chromatin (due to the DNA w/ affinity for acidophilic red dye -visible strands of nuclear chromatin -visible nucleoli -presence of primary granules |
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the 3 most immature neutrophils by order are
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myeloblast, promyelocyte, myelocyte
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hemophilia is characterized by
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Normal BT and high PTT
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HbA2 migrates together with HbC and _____ in alkaline pH
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HBE
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The priniciple Ags of the ABO system are
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O, A, and B
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2 blood systems excluding ABO, Rh, and MNS are
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-Kells
-duffy |
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the test that differentiates b/n immune and non-immune hemolytic anemia is
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indirect coombs test
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T/F Osmotic fragility test is decreased in hereditary sphero-cytosis
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F
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t/f parahemophilia is deficiency of factor 7
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F (its factor 5)
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t/f PTT evaluates the intrinsic system
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T
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t/f A leukemia is acute when more than 50% of blasts are seen in bone marrow
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F
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t/f the 3 most common abnormal hemoglobin are S, E, and D
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F (it's SCE in US)
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t/f factor 5 is called proaccelerin
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T
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what disease do u see lymphocytosis?
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whooping cough, viral infection, measles/mumps
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wat disease do u see in neutropenia?
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coppers deficiency, gaucher disease
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wat disease do u see in thrombocytosis?
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RA/TB
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what disease do u see in high PTT but normal PT
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VWD
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hemoglobin CC disease associated with
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codocytes
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lead poisoning is associated with
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basophilic stippling
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multiple myeloma is associated with
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rouleaux
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sickle cell anemia is associated with
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drepanocytes
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thalassemia is assocated with
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hypochromia
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vitamin B12 deficiency is associated with
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macrocytes
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which coagulation factor deficiencies are not related with hemorrhagic manifestations? how are they usually inherited?
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-contact factors, 11, 12, hmwk, fletcher
-autosomal recessive |
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wat is seen in aplastic anemia?
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dohl bodies
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wat is seen in human monocytic ehrlichiosis?
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vavuolated monocytes
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wat disease would u see in thrombocytopenia?
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Aplastic anemia
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wat disease would u see High ESR
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TB
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wat disease would u see high PTT and normal PT
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VWD
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name the coagulation factors that are thrombin sensitive
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1, 5, 8, 13
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name the coagulation factors that are vit K dependent
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2, 7, 9, 10
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name the coagulation factors that are contact factors
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11, 12, HMWK, fletcher
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name the intrinsic coagulation factors
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8, 9, 11, 12 (hageman), HMWK, fletcher
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name the extrinsic factors
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2, 7
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name the common coagulation factors
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5, 10
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serum does not contain wat coagulation factors?
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1, 2, 5, 8, 13 (only 7, 9, 10)
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