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39 Cards in this Set

  • Front
  • Back

Basic structural and functional unit of the kidney

Nephron

The _____ is is highly impermeable to water

Ascending loop of henle

Renal blood flow volume

1200 ml/min

Renal plasma flow?

600-700mL/min

Resembles a Sieve

Glomerulus

Glomeruluz can filter plasma substances with MW of?

<70,000 daltons

Why does Albumin(69,000Da) cannot pass through glomerulus

Because of shield of negativity

What are the plasma substances that cannpasz through glomerulus

Salts, Water, amino acids, glucose and urea

Renal threshold for glucose

160-180 mg/dL

Major site of reabsroption of plasma substances

Proximal convoluted tubules

Regulates water reabsorption

Anti diuretic hormone

Regulates sodium reabsorption

Aldosterone

Effects of angiotensin II

Release of ADH and aldosterone, vasoconstriction, corrects renal blood flow

Where does renin being produced

Juxtaglomerular cells

Inability to produce an acid urine

Renal tubular acidosis

Used to evaluate glomerular filtration

Clearance tests

Most common clearance test

Creatinine

Gold standard clearance test

Inulin

Creatinine clearance formula

C=UV/P x 1.73m2/A

Variables in cockgroft and gault

Age, sex and bodyweight in kg

Patient is deprived of fluid for 24 hours

Fishberg test(obsolete)

Major organic substance in urine

Urea

Major inorganic substance in urine

Chloride

Principal salt in urine

NaCl

For routine and qualitative UA

Random specimen

Ideal specimen for routine UA and pregnancy test

First morning

For routine screening and bacterial culture

Midstream cleancatch

For bacterial culture

Catheterized

Bladder urine for anaerobic bacterial culture and urine cytology

Suprapubic aspiration

Specimen for prostatic infection

Three-glass technique

How to determine prostatic infection in urine using 3 glass technique

If the no. Of WBC and bacteria in the 3rd spx is 10x > 1st spx

What is the use of 2nd spx in 3d glass technique

For control

Process that provides documentation of proper sample identification from the time of collection to the receipt of laboratory results

Chain of custody

Required urine volume for drug specimen

30-45 mL

Temperature of urine for drug specimen

32.5 - 37.5 °c within 4 minutes

Least affected in unpreserved urine

Protein

Preservative of choice for routine UA and urine culture

Refrigeration

Use for culture transport of urine

Boric acid

Excellent sediment preservative

Formalin