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33 Cards in this Set
- Front
- Back
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Dopamine blocking drugs
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- Haloperidol
- chlorpromazine - trifluoperazine - Sulpiride - pimozide |
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Haloperidol
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Dopamine blocking drugs, schizophrenia
most likely to cause EPS Less tendency to cause anticholinergic AE |
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chlorpromazine
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Dopamine blocking drugs, schizophrenia
very sedative moderate extra-pyramidal side-effects |
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trifluoperazine
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Dopamine blocking drugs, schizophrenia
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Sulpiride
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Dopamine blocking drugs, schizophrenia
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pimozide
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Dopamine blocking drugs, schizophrenia
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block serotonin receptors reducing side effects and ve/+ve symptoms
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atypical antipsychotic drugs
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atypical antipsychotic drugs
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clozapine,
olanzapine, quetiapine, risperidone, ziprasidone amisulpride |
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clozapine
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-atypical antipsychotic drug.
-Superior anti-suicidal effects. -Used in stabilization phase -Causes agranulocytosis in ~2% of patients (regular haematological monitoring is mandatory) - weight gain / diabetes - no Hyperprolactinaemia |
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olanzapine
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atypical antipsychotic drug
-clozapine analogue -relapse prevention and in acute schizophrenia -*Weight gain*/diabetes, sedation and anticholinergic effects (same as clozapine) BUT NO AGRANOLOCYTOSIS - doc for bipolar |
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quetiapine
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atypical antipsychotic drugs
-low incidence of extrapyramidal effects - anticholenrgic s/e - drowsiness - *no Hyperprolactinaemia* |
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risperidone
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-atypical antipsychotic drugs
-weight gain, hyperprolactinaemia and EPS at higher doses -lack of effect at muscarinic and histaminic receptors is beneficial in minimising sedation and cognitive impairment - lowest risk of diabetes |
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ziprasidone
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atypical antipsychotic drugs
- Not associated with weight gain, hyperlipidaemia or elevated glucose levels -Low incidence of sedation, no anticholinergic effects - May increase QTc interval |
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amisulpride
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atypical antipsychotic drugs
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ECT
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Schizophrenia (acute episodes) , Depression, bipolar
Anticonvulsants should be discontinued prior to treatments |
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Considerations for Atypical Drugs
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only available as oral medications (no depot)
fewer EPS broader spectrum of action first choice for new presentation |
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Considerations for Dopamine receptor blockers (typical antipsychotics)
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first line agents, less useful for negative symptoms,
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thioridazine
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Traditional Antipsychotic, switch to if EPS side effects are a problem
- *worst sedation* |
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benztropine
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added to antipsychotic medications for its anticholinergic effects (treat epse) and treat acute dystonia
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dantrolene
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muscle relaxant, treats Neuroleptic malignant syndrome
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orlistat
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Used to treat wt gain. Doesn't cross into CNS (unlike Sibutramine)
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Zolpidem
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for the short term treatment of insomnia
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Zaleplon
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for treating sleep onset latency but not for maintaining sleep
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melatoni
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jet lag
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Dopaminergic agents
Levodopa ropinirole, pramipexole, cabergoline |
treatment of RLS
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Methylphenidate dexamphetamine
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Central nervous system stimulants for Treatment of narcolepsy
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clomipramine
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Inhibitor of REM cycle, helps with cataplexy
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Movicol
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Delivers water to the colon and hydrates feces
DOESN't work on fermentation or the other stuff |
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Neuropathic pain
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TCA
-anticonvolsant gabapentin (300mg tid upto 2400mg/day) - Capsacin or systemic local anesthetic |
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Durogesic patch
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- take MS Contin for 12-18 hours after the first Durogesic patch has been applied
- Apply 1 patch every 3 days - all the other patch mombo jumbo, i can think of 3, can you? |
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Hypomania lasts?
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atleast 4 days and atleast 3 symptoms of mania - gross lapses of judgement
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Venlafaxine
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used for everything
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Lamotrigine
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Hard to treat bipolar
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