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24 Cards in this Set
- Front
- Back
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Which pts HAVE to be screened for HIV?
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1. Pts with Positive PPD
2. Pts initiating TB tx 3. Pts with STI |
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Which pts are offered the "OPT OUT" screening?
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1. all pts 13-64y KNOW!!!
2. pregos |
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What are the 2 tests utilized in the Dx of HIV infection?
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1. Antibody testing (FDA Approved)
12. RNA testing: VIRAL LOAD by molecular method |
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How long does it take to get the results back from an Antibody test, when determining Dx of HIV infection?
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Usually positive within 3 MONTHS of Primary HIV Ix
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Which of the HIV tests is used for CONFIRMING the Dx?
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RNA TESTING: VIRAL LOAD by molecular method
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What Viral Load is Positive for HIV Infection?
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Typical Range is 10k-100k copies RNA/mL
- Low Level Viral Load (<1000) can be a false (+) sometimes |
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What type of cells are Targeted by the HIV Infection?
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CD4 Lymphocytes!!!!!
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What range is NORMAL for CD4 cells?
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500-1500 cells/mL= NORMAL range of CD4
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Which cells are markers for determining immune function in our bodies?
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CD4 T lymphocytes
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At what level of CD4 cells is indicative of AIDS? death?
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AIDS= <200 CD4 cells/mL
Death= <50!! KNOW! |
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T/F: as a healthcare worker your highest risk of HIV Ix is in the hospital or other healthcare facility?
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FALSE!!! rather its outside the hospital where you are sexually active.
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Fasting growing group of new HIV infected individuals?
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Teenagers and older individuals
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PPL with HIV that are Tx'd with drugs are...?
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1. Living longer (avg to age of 69)
2. can get life insurance 3. will NOT eventually die with AIDS |
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T/F HIV is infecting other countries to a much greater degree than in the US?
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TRUE! Especially in China.
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T/F: if Prego it is best to start treatment after delivery? Why/Why not/
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FALSE!!! Giving mother Tx ASAP, allows for passivie immunity to the child.
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What are the 4 main causes of Treatment Failure?
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1. Prescriber Error/or incomplete adherence--> leads to RESISTNACE!!! MAIN CAUSE OF TX FAILURE
2. Limited drug/regimen potency 3. Pharmco-kinetic/dynamic 4. Inadequate activation (cell or compartment) |
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What are the reasons that HIV is becoming so resistant to Tx?
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1. Rev. Txcriptase is error prone= tons and tons of SINGLE POINT mutations.
2. SPM on RTM184 leads to high level drug resistance 3. MONOtherapy leads to replacement of Wild Type Virus with HIghly Resistant Virus w/in days to weeks! 4. Cross resistance with other drug lcasses 5. Discontinuing ART (antiretroviral Tx) |
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Who is best at predicting Adherence?
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Family Member
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Tx for HIV can be provided by...?
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1. PCP
2. Specialist |
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Is HIV Tx lifelong?
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YES!!!
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When is the best time to tx Post exposure Prophylaxis?
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ASAP!!!!!!
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What are the 3 main reasons for DISCONTINUING ART?
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1. TOXICITY
2. Virologix failure 3. Non Adherence |
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What are the Long Term Complications of ART?
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1. Dyslipidemia/CHD
2. Hepatotoxicity 3. Abnormalities of body composition (skinny face, fatty neck/back) |
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Who is an HIV SPECIALISTS?
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Family Practice.
"HIV is a Primary Care Specialty" |
