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20 Cards in this Set
- Front
- Back
What is the clinical presentation of someone with an intracranial mass?
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Increased ICP
-Mass effect of tumor -Hydrocephalus Focal symptoms based on location Seizures Hemorrhage |
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Case:
8YO male Headaches, lethargy, neck pain, sudden loss of consciousness consciousness |
Can be caused by hydrocephalus, among other things
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Case:
70 YO woman Headaches, forgetfulness, personality changes, problems with ADLs over past 3 MO |
Frontal lobe problems
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What are characteristics of frontal lobe mass lesions?
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Behavioral change
Poor decision making Decreased work performance Motor weakness (if posterior) |
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What are characteristics of parietal mass lesions?
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Contralateral motor weakness (if anterior)
Contralateral sensory changes |
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What are some characteristics of dominant parietal lobe syndromes?
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Agraphia without alexia
Right/left disorientation Acalculia: Loss of the ability to perform simple arithmetic calculations Finger agnosia: inability to interpret sensations |
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What are some of the characteristics of temporal lobe lesions?
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Language disturbances
Memory/visual impairment Seizures are common |
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What are some of the characteristics of cerebellar lesions?
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Hydrocephalus
Gait ataxia Dysmetria of the arms: a lack of coordination of movement typified by the undershoot or overshoot of intended position Speech changes (fluency, pitch) |
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What are the advantages of CT for brain imaging? Disadvantages?
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Advantages:
Fast Very available Can be done without sedation Disadvantages: Radiation Less |
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What are the advantages of MRI for brain imaging? Disadvantages?
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Advantgaes:
No radiation More accurate Disadvantages: Slower Less available Sedation required |
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What's the use of spectroscopy in the brain?
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It allows you to see if there are characteristic patterns of metabolism in the brain tissue that allow you to differentiate between different types of pathologies
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What's on your differential for tumor-like masses in the brain?
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Congenital:
Arachnoid cyst Hematoma Inflammatory: Acute demylenating processes MS Infectious: Bacterial abscess Fungal/parasitic Herpes encephalitis Vascular: AVM Intracranial aneurysm Intracranial hemorrhage |
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If there's a tumor in the posterior fossa, what types of tumors should you think?
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Pliocytic astrocytoma
Brainstem glioma Medulloblastoma Ependymoma |
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If you have a tumor that's metastasized to the brain, what type is it, most likely?
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1. LUNG (70%)
2. Breast (20%) |
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What are some of your options when presented with an intracranial mass?
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Serial imaging: is the tumor growing/not?
Tissue diagnosis: invasive, depends on what the patient wants |
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What are indications for resecting a tumor vs. performing a biopsy?
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It's in an accessible part of the brain
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What are the benefits to resection vs. biopsy?
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Reducing the mass effect controls the symptoms
You have a better prognosis from reducing the tumor cells |
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In what situations should biopsy rather than resect?
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If the tumor is located in a more eloquent cortex.
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What occurs during an operation that assists with management of a patient?
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Frozen sections
Lets you know what kind of a tumor it is: should I take it all out; what are the margins, etc. |
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What are some other treatment modalities for intracranial masses?
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Corticosteroids: palliative for people with lots of edema
Chemo: dependent on tissue type Radiation: depends on the tissue type. |