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29 Cards in this Set
- Front
- Back
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name the two herbs that have drug therapeutic actions in HIV |
Echinacea spp Melissa officinalis |
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name signs and symptoms for systemic lupus erythematosus
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mallor rash & discoid rash
photosensitivity arthritis renal disorder Oral ulcers Serositis Leukopenia, lymphonenia |
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Herbs with specific actions for inflammatory mediator modulation |
- Boswellia serrata inhibit 5-lipooxygenase activity, suppress leukotriene - Harpagophytum procumbens inhibit COX-2, pro- inflammatory cytokines - Curcuma longa – non-steroidal anti-inflammatory urtica longa, tylophora indica, hemidesmus indicus, foeniculum vulgare |
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How is Echinacea and HIV have a similar effect
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HIV reduces the production of interleukin2 and interferon gamma |
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Herbs with specific actions for viral replication |
Hypericum perforatum herpes Melissa officinalis, preventing viral fixation to the cell Glycyrrhiza glabra inhibits virus growth. HSV, HIV Thuja occidentalis several viruses |
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explain harpagophytum procumbens role inflammatory cytokines |
iridoid glycosides inhibit COX-2 pro inflammatory cytokines. increases gastric secretions |
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explain how boswellia serrata is involved as an inflammatory cytokine |
non-steroidal anti-inflammatory agents inhibit 5-lipoxygenase cytokines and suppress leukotrienes |
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Herbs for immune cell stimulation |
Echinacea spp - faster response time Astragalus membranaceus -coughs colds Andrographis paniculata Uncaria tomentosa |
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Immune modulators |
Echinacea spp Andrographis paniculata Astragalus membranaceus Hydrastis canadensis Scutellaria baicalensis Withania somnifera |
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Discuss interactions with anti virals NRTIS and give examples |
NRTIs + aloe work synergistically NRTIs + panax delayed resistance mutation |
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Discuss interactions with immuno suppressant and give examples |
Glycyrrhiza glabra - potentiates, need less Curcuma longa aids action, reduces drug absorption Echinacea - too immune stim Hypericum perforatum - lowers drug effect Silybum marianum protects against drug induced liver damage |
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How is Melissa officinalis useful in HIV
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anti-viral in T-cell lines and macrophages
inhibit HIV-1 reverse transcriptase occupy viral receptors in cell-membrane proteins, preventing viral fixation to the cell |
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Anti viral herbs |
Hypericum perforatum Melissa officinalis Glycyrrhiza glabra Uncaria tomentosa Echinacea spp Thuja occidentalis |
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Immune supporting herbs |
Andrographis paniculata Uncaria tomentosa Echinacea spp |
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Which may potentiate the effects of prednisone(corticosteriod) and may aid withdrawal |
Glycyrrhiza glabra - potentiates, need less Allium sativum immune stim, reduces drug effect Calendula Celery seed coleus lavandula CHECK THIS!! |
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Alkylating agents (cyclophosphamide) immune supp interactions |
Astragalus membranaceus Echinacea spp - too stimulating Curcuma longa aids action, reduces absorption Eleutherococcus senticosus - reduce drug SE |
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Anti V Acidovir (herpes cream) interactions
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Astragalus + enveloped anti V Acidovir enhance activity against herpes |
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Discuss interactions with anti virals protease inhibitors and give examples Lower drug serum levels |
Allium sativum Hypericum perforatum Echinacea spp good for opportunistic short term Melissa off anti viral potentiates Glycyrrhiza glabra inhibits HIV Virus Thymus vulgaris anti v potentiates |
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Glycyrrhiza glabra immune actions and indications |
HSV, varicella zoster virus and HIV. With oral ingestion, Glycyrrhizin is converted to glycyrrhetinic acid , therefore oral doses no systemic anti-viral effects. |
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Salvia officinalis & Rheum palmatum indication |
Herpes As effective as acyclovir cream. |
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Hypericum perforatum indications |
Anti viral Herpes |
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Thuja Occidentalis actions and indications |
Several viruses, structure of which includes enveloped and non-enveloped viruses with DNA and RNA nucleic acids. |
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Immune stimulating herbs |
Astragalus membranaceus Andrographis paniculata Uncaria tomentosa Echinacea spp |
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Calendula officinalis actions and indications |
Inhibits the growth of bacteria, fungi and viruses
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Tabebuia avellanedae indications |
Effective against Candida albicans and Trichophyton (the fungus responsible for ringworm). Intestinal inflam |
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Chelidonium majus |
Warts Papillomas |
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Lymphatic herbs |
Echinacea spp Phytolacca americana Calendula officinalis Iris versicolor |
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Tonic and adaptogens herbs To maintain vitality |
Withania somnifera Eleutherococcus senticosus Panax ginseng Ganoderma lucidum Glycyrrhiza glabra |
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Panax ginseng actions |
Improved immune response of alveolar macrophages, chemotaxis, phagocytic activity and intracellular killing |
