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31 Cards in this Set

  • Front
  • Back
what is dysmenorrhea?
painful menstruation
what ages does primary dysmenorrhea usually occur in?
17-22
what is primary dysmenorrhea?
painful menstruation in the absence of pelvic pathology
what is secondary dysmenorrhea?
painful menstruation resulting from an identifiable pelvic pathology
what do sloughing endothelial cells release? (2)
PGF2
PGE2
what do releasing prostaglandins during menses cause? (2)
myometrial contraction
vasoconstriction
when does primary dysmenorrhea usually set in?
within 2 years of menarche
when does lower abdominal and pelvic pain begin and end with primary dysmenorrhea?
onset of menses
ends 48-72 hours later
what are 7 pathological causes of secondary dysmenorrhea?
endometriosis
adenomyosis
IUD use
pelvic congestion
fibroids
pelvic inflammatory disease
ovarian cysts
what are 4 clinical features of secondary dysmenorrhea?
infertility
heavy or irregular menstrual flow
dyspareunia
vaginal discharge
how do anti-prostaglandins help with primary dysmenorrhea?
decrease COX enzyme to inhibit prostaglandin synthesis and metabolism
when should NSAIDs be given for primary dysmenorrhea?
at the earliest onset of symptoms, sometimes 1-2 days before
what are tocolytic agents?
analgesics
what are 2 tocolytic agents?
salbutomol
nifedipine (ca2+ channel blocker)
how should you treat resistant primary dysmenorrhea cases?
proestogens
what are 2 proestogens?
medroxyprogesterone
dygogesterone
how do proestogens work?
decrease endometrial lining
what has been shown to be as effective ibuprofen in treating primary dysmenorrhea?
low-level topoical heat
what types of diets are helpful in primary dysmenorrhea and why?
diets low in fat and meat products because they decrease the serum sex binding globulin which then decreases the duration and intensity of dysmenorrhea
what is endometriosis?
growth of endometrial tissue in sites outside the endometrial cavity
where can endometrial tissue be found in endometriosis? (4)
pelvic cavity
ovaries
uterosacral ligaments
pouch of douglas
what are 6 symptoms of endometriosis?
dyspareurnia
dysmenorrhea
chronic LBP
pelvic pain
adnexal masses
subfertility
what percentage of dysmenorrhea patients have endometriosis?
40-60%
what percentage of patients with subfertility have endometriosis?
20-30%
what is the most common age for diagnosis of endometriosis?
40
what are 2 risk factors for endometriosis?
environmental toxins
hereditary
what is coelomic metaplasia?
the theory that certain cells, when stimulated, can transform themselves into a different kind of cells
what is the only diagnostic test that can reliably rule our endometriosis?
laparoscopy
what are 4 medical options for endometriosis treatment?
oral contraceptives
progestins
androgenic agents
GnRH analogues
how should you base treatment for endometriosis?
side effect profiles
what are 3 surgical options for endometriosis?
laparoscopy
surgical laser or thermal ablation
surgical excision