Clin Path Vocab

Front 1

Megakaryocyte

Back 1

Platelet Precursor

Front 2

Metarubricyte

Back 2

Precursor before reticulocyte for RBCs; last RBC precursor with nucleus

Front 3

Reticulocyte

Back 3

RBC precursor

Front 4

Metamyelocyte

Back 4

Neutrophil precursor before bands

Front 5

Leukemia

Back 5

Non-physiological uncontrolled and disorderly production of one or more cell lineages in the marrow

Front 6

Myelodysplasia

Back 6

A marrow disorder characterized by maturation defects and abnormal morphology in several cell lines.

Front 7

Myelofibrosis

Back 7

Replacement of the bone marrow by fibrous tissue

Front 8

Myelophthisis

Back 8

Replacement of normal hematopoietic tissue with a proliferation of abnormal cell.

Front 9

Myelitis

Back 9

Inflammation of the bone marrow

Front 10

Dohle Bodies

Back 10

Aggregates of rER in neutrophils, it is a characteristic of toxic change

Front 11

Regenerative Left Shift

Back 11

The number of mature cells is greater than the number of immature cells

Front 12

Degenerative Left Shift

Back 12

The number of immature cells is greater or equal to the number of mature cells or the presence of immature cells in the absence of an increase in the mature cells

Front 13

Leukemoid Response

Back 13

Marked leukocytosis (greater than 75,000) with marked neutrophilia

Front 14

Pelger-Huet Anomaly

Back 14

Failure of the nucleus of mature neutrophils to segment

Front 15

Neutrophilia

Back 15

Increase numbers of circulating neutrophils

Front 16

Neutropenia

Back 16

Decrease in the number of circulating neutrophils

Front 17

Leukocytosis

Back 17

An increase in the totals levels of circulating WBCs

Front 18

Leukopenia

Back 18

A Decrease in the total levels of circulating WBCs

Front 19

Lymphocytosis

Back 19

An increase in circulating lymphocytes

Front 20

Lymphopenia

Back 20

A decrease in circulating lymphocytes

Front 21

Monocytosis

Back 21

An increased of monocytes in the blood

Front 22

Monocytopenia

Back 22

A decrease of monocytes in the blood

Front 23

Eosinophila

Back 23

An increase in eosinophils in the blood

Front 24

Eosinopenia

Back 24

A decrease in eosinophils in the the blood

Front 25

Basophilia

Back 25

An increase in basophils in the blood

Front 26

Hematocrit

Back 26

Pack Cell Volume; Ratio of RBCs to whole blood

Front 27

MCV

Back 27

Mean cell volume; Volume of the average RBC

Front 28

Normocytic

Back 28

Normal mean cell voume

Front 29

Macrocytic

Back 29

Volume of the average RBC is larger than normal; increased MCV

Front 30

Microcytic

Back 30

Volume of the average RBC is smaller than normal; decreased MCV

Front 31

MCHC

Back 31

Mean Cell Hemoglobin concentration; hemoglobin concentration in the average RBC

Front 32

Normochromic

Back 32

MCHC is normal; the average RBC has normal hemoglobin concentration

Front 33

Hypochromic

Back 33

MCHC is decreased; the average RBC has a reduced hemoglobin concentration

Front 34

Hyperchromic

Back 34

MCHC is increased; the average RBC has an increase in hemoglobin concentration; artifact; does not occur in vivo

Front 35

MCH

Back 35

Mean cell hemoglobin; average amount of hemoglobin content in a RBC

Front 36

RDW

Back 36

Red cell distrubution width; variation of the red cell volume distrubution (how much size of RBC varies)

Front 37

Reticulocytes

Back 37

Immature, anucleated RBCs with residual RNA and mitochondria

Front 38

Aggregate Reticulocytes

Back 38

Cat reticulocytes that are similar to other species; increase with regenerative anemia

Front 39

Punctate Reticulocytes

Back 39

Red cells in cats with small blue dots; can't be used to assess bone marrow response

Front 40

Rouleaux Formation

Back 40

Coin-like stacking of RBCs

Front 41

Agglutination

Back 41

Clumping of RBCs

Front 42

Polychromasia

Back 42

Variation in RBC staining; think reticulocytes

Front 43

Hypochromasia

Back 43

Increased in central pallor of RBCs; usually caused by interference with hemoglobin production

Front 44

Anisocytosis

Back 44

Variation in RBC cell size; relates to RDW

Front 45

Nucleated RBC

Back 45

younger red cell that have retained their nucleus; usually metarubricytes

Front 46

Poikilocytosis

Back 46

Variation in red cell shape

Front 47

Discocyte

Back 47

Biconcave discoid RBC

Front 48

Elliptocyte/Ovalocyte

Back 48

Oval-shaped RBC; Camelids

Front 49

Echinocytes

Back 49

Crenated cells; Red cells with evenly spaced projections on the surface

Front 50

Acanthocytes

Back 50

Red cells with irregular finger-like projections on the surface

Front 51

Eccentrocytes

Back 51

Red cells where the hemoglobin has condensed to one portion of the cell; associated with oxidative damage

Front 52

Schistocytes

Back 52

Variably sized, irregular red cell fragments; caused by mechanical trauma

Front 53

Spherocytes

Back 53

small, round, darker, staining red cells that lack central pallor

Front 54

Leptocytes

Back 54

Thin, often hypochromic-appearing red cells that have an increased membrane-to-cytoplasm ratio; Includes Codocytes, stomatocytes, knizocytes, and keratocytes

Front 55

Codocytes

Back 55

Bell-shaped red cells that have the appearance of a bull's eye; non-specific

Front 56

Stomatocytes

Back 56

Cup shaped cells that appear to have a slit-like formation near the center of the cell

Front 57

Knizocytes

Back 57

Triconcave-like and appear to have a central bar of hemoglobin

Front 58

Keratocyte

Back 58

Red cells that appear to have a vesicle or 1/2 pointed projections

Front 59

Basophilic Stippling

Back 59

Aggregates of RNA in red cells; Appear as small, faint blue dots

Front 60

Howell-Jolly Bodies

Back 60

Nuclear remnants in red cells that are usually a single, small dark blue dot

Front 61

Eccentrocytes

Back 61

Red cells where the hemoglobin has condensed to one portion of the cell; associated with oxidative damage

Front 62

Schistocytes

Back 62

Variably sized, irregular red cell fragments; caused by mechanical trauma

Front 63

Spherocytes

Back 63

small, round, darker, staining red cells that lack central pallor

Front 64

Leptocytes

Back 64

Thin, often hypochromic-appearing red cells that have an increased membrane-to-cytoplasm ratio; Includes Codocytes, stomatocytes, knizocytes, and keratocytes

Front 65

Codocytes

Back 65

Bell-shaped red cells that have the appearance of a bull's eye; non-specific

Front 66

Stomatocytes

Back 66

Cup shaped cells that appear to have a slit-like formation near the center of the cell

Front 67

Knizocytes

Back 67

Triconcave-like and appear to have a central bar of hemoglobin

Front 68

Keratocyte

Back 68

Red cells that appear to have a vesicle or 1/2 pointed projections

Front 69

Basophilic Stippling

Back 69

Aggregates of RNA in red cells; Appear as small, faint blue dots

Front 70

Howell-Jolly Bodies

Back 70

Nuclear remnants in red cells that are usually a single, small dark blue dot

Front 71

Heinz body

Back 71

Denatured hemoglobin in a red cell; appears as a pale protruding round structure

Front 72

Polycythemia

Back 72

Increased total RBC mass in the blood