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19 Cards in this Set
- Front
- Back
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_ means decreased circulating neutrophils.
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leukopenia
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In extreme cases of leukopenia, where there are NO circulating neutrophils, this is called?
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agranulocytosis
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what is the MC cause of leukopenia?
-myelopdysplastic syndrome -severe infection -bone marrow failure -drugs |
drugs; such as carbimazole, cytotoxic chemo, RA drugs like sulfasalazine, and some NSAIDs
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_ may underlie neutropenia.
-smoking -IV drug use -etohism |
etohism
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Myelodysplastic syndrome is common in _ patients.
-infant -pediatric -adult -geriatric |
geriatric
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All of the following except what can cause neutropenia.
-pneumococcal infection -typhoid -meningococcal infection -viral infection |
not meningococcal infection
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t/f
bone marrow failure, particularly from hematological malignancy, such as leukemia, usually affects all cell lines (pancytopenia). |
true
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pt's are at very serious risk of infection when their neutrophil counts are below?
-0.5 -1.0 -2.0 -5.0 |
<0.5 the risk of infection becomes significant
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all of the following except 1 can be found in chronically neutropenic patients.
-mouth ulceration -geographic tongue -oral candidiasis |
not geographic tongue
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rheumatoid arthritis with high rheumatoid factor is AKA?
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Felty's syndrome
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t/f
most pt's with mild-moderate neutropenia have no symptoms. |
true
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t/f
in pt's with leukopenia, infection can appear very rapids and produce septic shock |
true
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All except 1 of the following are 'typical' pathogens of leukopenic pts.
-H. flu -S. Aureus -strep -gram negative bacilli |
not H. Flu
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how do you definitively determine which but is causing problems in the neutropenic patient?
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blood cultures; give high dose broad spectrum antibiotics
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Treatment with granulocyte-colony stimulating factor may sometimes help to shorten a period of neutropenia, depending on the cause. This treatment is especially helpful in __ neutropenia.
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chemo-induced
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_ is when there is a significant decrease in the number of lymphocytes.
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lymphopenia
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Which of the following may cause lymphopenia?
-HIV -CMV -SLE -EBV -all of the above |
all of the above
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T-cell deficiency predisposes a pt to infection with what bugs?
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viruses
pyogenic bacteria fungi PCP cryptosporidium |
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t/f
B cell deficiencies predispose to pyogenic bacterial infection |
true
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