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22 Cards in this Set
- Front
- Back
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t/f
bone marrow can increase red cell production to seven time the normal level, this is inadequate and anemia results. |
true
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all of the following except what are features of hemolytic anemia?
-pallor -hepatomegaly -splenomegaly -jaundice |
not hepatomegaly
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A pt with hemolytic anemia may end up with _ gall stones due to the chronic hyperbilirubinemia, which may lead to obstructive jaundice.
-cholesteral -mixed -pigmented stones |
pigmented stones
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all of the following are congenital causes of hemolytic anemia except 1?
-hereditary spherocytosis -transfusion reaction -G6PD deficiency -pyruvate kinase deficiency -sickle-cell disease -thalassemia |
transfusion reaction is an acquired form of hemolytic anemia
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All of the following are acquired causes of hemolytic anemia except?
-infection -autoimmune -drug induced -prosthetic heart valve -hemolytic transfusion reaction -microangiopathic (HUS) -nocturnal hemoglobinuria -all are acquired |
all are acquired forms of hemolytic anemia
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An increased level of unconjugated bilirubin, elevated LDH, and indicative of _ anemia.
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hemolytic
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LDH is elevated in hemolytic anemia due to?
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released from damaged rbc's
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low or absent haptoglobin levels are found in hemolytic anemia since haptoglobin binds avidly to free plasma _.
-hemoglobin -cytosol -cytoskeletons |
hemoglobin
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an elevated reticulocytic count is increased in red blood cell _.
-destruction -production |
production
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all of the following are true about hereditary spherocytosis except 1.
-autosomal dominant -typically presents in childhood with pallor jaundice -splenomegaly common -treatment with steroids |
the treatment is not steroids but splenectomy
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After splenectomy patients are at risk for infection with _ bacteria.
-all -capsulated -encapsulated |
encapsulated
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Prior to a splenectomy patients should receive all of the following immunizations except?
-pneumovax -HiB -varicella -meningococcus |
all but varicella
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pt's with a splenectomy should receive life long antibiotic prophylaxis with ??
-keflex -erythromycin -penicillin -doxycycline |
penicillin
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t/f
red cell enzyme deficiency is involved in red cell glucose metabolism can result in hemolytic anemia. |
true
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what are the most important red cell enzyme deficiencies? (2).
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G6PD and pyruvate kinase deficiency
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Hemolytic uremic syndrome is characterized by all of the following except?
-microangiopathic hemolytic anemia -thrombocytopenia -liver failure -renal failure |
not liver failure
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Which of the following bugs is sometimes responsible for small epidemics of HUS?
-pseudomonas -ecoli (0157) -h. flu -enterococcus |
e coli 0157
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which of the following a classic in G6PD?
-philadelphia chromosome -heinz bodies -ritz cells |
heinz bodies
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all of the following are true about G6PD except what?
-NADPH (reduced) -leads to hemolytic anemia -common in subtropics/tropics -autosomal dominant -supha and primaquine can induce hemolytic event |
not autosomal dominant but is x linked
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t/f
fava bean ingestion can trigger a hemolytic attack in G6PD |
true
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t/f
In G6PD anemia, the disease is usually self-limiting and supportive care is the only requirement. Chronic hemolytic anemia is rare. |
true
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_ deficiency is a rare autosomal recessive disease. Usually appears in childhood with anemia and jaundice.
-G6PD -pyruvate kinase deficiency -TTP -HUS |
pyruvate kinase deficiency
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