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29 Cards in this Set
- Front
- Back
whole blood (vol.)
|
92% tissues & fluids
8% blood |
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erythrocyte volume
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5.2 million/mm +/- 1 mil
|
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platelet volume
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250,000 +/- 100,000
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leukocyte volume
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4.000-10,000
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protein volume
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albumin 55%
globulins 38% fibrinogen 7% |
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leukocyte differential
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neutrophils 55-60%
lymphocytes 28-30% monocytes 10% eosinophils 4-5% basophils <1% |
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MCV
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mean cell volume: (HG/RBC) x 10 (> macrocytic, <microcytic). how big is the red cell?
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MCH
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how much hemogloin is in each corpuscle: Mean cell hemoglobin
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MCHC
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mean cell hemoglobin concentration
tells amount of color chromic |
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RDW
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red cell disc width
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anicocytosis
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abnormal- unequal sz. too much cell size variation
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macrocytic
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megaloblastic anemia
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microcytic
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small
hypochromic, pale |
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normocytic anemia
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77% of all chronic disease
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microcytic hypochromic anemia
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17% of all chronic disease
Small & pale |
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5 microcytic anemias
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Fe deficiency
thallassemia sickle cell sideroblastic hemiglobinopathies |
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HCT
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hematocrit: % of cellular elements of the blood
5.2+/- 1 million (normal red count) |
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cell size
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micro
normo macro ....cytic |
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color of RBC
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pale= hypo
normal+normo dark= hyper..................chromic |
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shape of RBC
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sickle
shphero elipto ovalo...................cytosis |
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RBC degrades into....
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protein (100% recycled into the AA pool)
Hb-billerubin, all excreted Fe 2+, eat 10mg/day |
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body absorbs most iron into the
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duodenum
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hemochromatosis
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Fe+2 UP
TIBC down (total Fe binding cap) transferrin UP (binds and removes Fe+2)' ferritin DOWN |
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Yellowness
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jaundice
carotenemia |
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Urobilin
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makes pee yellow
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exact location of red cell lysis
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macrophages of liver and spleen
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what is the exact molecule that conjugates bilirubin
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glucuronic acid
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how is the billerubin transported?
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unconjugated in blood w/ albumin
OR conjugated in water impermeable ducts to be sequestered in the gakk bladdy |
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malaria
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most common cause of hemolysis
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