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108 Cards in this Set
- Front
- Back
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Abdominal pain Ascites Hepatomegaly |
Budd-Chiari syndrome |
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Abdominal pain Diarrhea Leukocytosis recent antibiotic use |
C. diff infection |
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Achilles tendon xanthoma |
Familial hypercholesterolemia (decr. LDL receptor signaling) |
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Adrenal hemorrhage Hypotension DIC |
Waterhouse-Friderichsen syndrom (meningococcemia) |
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Anaphylaxis following blood transfusion |
IgA deficiency |
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Anterior drawer sign |
Anterior cruciate ligament |
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Arachnodactyly Lens dislocation Aortic dissection Hyperflexible joints |
Marfan syndrome (fibrillin defect) |
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Athlete with polycythemia |
Secondary to erythopoietin injection |
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Back pain Fever Night sweats |
Pott disease (vertebral TB) |
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Bilateral acoustic schwannnomas |
NF Type 2 |
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Bilateral hilar adenopathy Uveitis |
Sarcoidosis (non-caseating granulomas) |
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Black eschar on face of pt w/ DM ketoacidosis |
Mucor or Rhizopus fungal infection |
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Blue sclera |
OI (Type I Collagen Defect) |
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Bluish line on gingiva |
Burton line (lead poisoning) |
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Bone pain Bone enlargement Arthritis |
Paget disease of bone (incr. osteoblastic and osteoclastic activity) |
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Bounding pulses Diastolic heart murmur Head bobbing |
Aortic regurgitation |
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Butterfly facial rash Raynaud phenomenon young female |
Systemic lupus erythematous |
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Cafe-au-lait spots Lisch nodules (iris hamartoma) Cutaneous neurofibromas Pheochromocytomas Optic gliomas |
NF Type 1 Pheochromocytoma Optic Gliomas |
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Cafe-au-lait spots (unilateral) Polyostotic fibrous dysplasia Precocious puberty Multiple endocrine abnormalities |
McCune Albright syndrome (mosaic G-protein signaling mutation) |
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Calf pseudohypertrophy |
Muscular dystrophy (Duchenne: X-linked frameshift of dystrophin gene) |
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Cervical lymphadenopathy Desquamating rash Coronary aneurysms Red conjunctivae Red tongue |
Kawasaki disease (treat: IVIG and aspirin) |
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Cherry-red spots on macula |
Tay-Sachs (ganglioside accumulation) Niemann-Pick (sphingomyelin accumulation) Central retinal artery occlusion |
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Chest pain Pericardial effusion/Friction Rub Persistent fever following MI |
Dressler syndrome (autoimmune)
(2-12 weeks post acute episode) |
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Chest pain w/ ST depressions on EKG |
Unstable angina (troponins -) NSTEMI (troponins +) |
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Child uses arms to stand up |
Gowers sign (Duchenne muscular dystrophy) |
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Child w/ fever develops red rash on face that spreads to body |
"slapped cheeks" erythema infectiosum/fifth disease: parvovirus B19 |
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Chorea Dementia Caudate degeneration |
Huntington disease (AD CAG repeat expansion) |
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Chorioretinitis Hydrocephalus Intracranial calcifications |
Congential toxoplasmosis |
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Chronic exercise intolerance w/ myalgia, fatigue, painful cramps, myoglobinuria |
McArdle disease (skeletal muscle glycogen phosphorylase deficiency) |
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Conjugate horizontal gaze palsy Horizontal diploplia |
Internuclear ophthalmoplegia (damage to MLF, unilateral or bilateral) |
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Cutaneous edema due to connective tissue deposition |
Myxedema: hypothyroidism Graves disease (pretibial) |
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Red urine in the morning Fragile RBCs |
Paroxysmal nocturnal hemoglobinuria |
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Renal cell carcinoma (bilateral) Hemangioblastomas Angiomatosis Pheochromocytoma |
von Hippel-Lindau disease (dominant tumor supressor gene mutation) |
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Resting tremor Rigidity Akinesia Postural instability Shuffling gait |
Parkinson disease (dopaminergic neuron loss in SNpc) |
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Retinal hemorrhages w/ pale centers |
Roth spots (bacterial endocarditis) |
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Severe jaundice in neonate |
Crigler-Najjar syndrome (congenital unconjugated hyperbilirubinemia) |
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Short stature Cafe au lait spots Thumb/radial defects Incr. incidence of tumors/leukemia Aplastic anemia |
Fanconi anemia (genetic loss of DNA crosslink repair, progresses to AML) |
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Single palmar crease |
Down syndrome |
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Situs inversus Chronic sinusitis Bronchiectasis Infertility |
Kartagener syndrome (dynein arm defect affecting cilia) |
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Skin hyperpigmentation Hypotension Fatigue |
Primary adrenocortical insufficiency (Addison disease) (incr. ACTH, incr. alpha-MSH) |
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Slow, progressive muscle weakness in boys |
Becker muscular dystrophy (X-linked missense in dystrophin) |
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Small, irregular red spots on buccal mucosa w/ blue-white centers |
Koplik spots (measles, rubeola) |
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Smooth, moist, painless wart-like white lesions on genitals |
Condylomata lata (secondary syphilis) |
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Splinter hemorrhages in fingernails |
Bacterial endocarditis |
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Cutaneous flushing Diarrhea Bronchospasm |
Carcinoid syndrome (right sided cardiac valvular lesions, incr. 5-HIAA - serotonin metabolite) |
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Dark purple skin Mouth nodules AIDS |
Kaposi sarcoma (assoc. w/ HHV-8) |
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Hyperventilation Deep, labored breathing |
Kussmaul respirations (diabetic ketoacidosis) |
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Dermatitis Dementia Diarrhea |
Pellagra (niacin/B3 deficiency) |
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Dilated cardiomyopathy Edema Alcoholism/malnutrition |
Wet beriberi (thiamine/B1 deficiency) |
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Dog/cat bite resulting in infection |
Pasteurella multocida (cellulitis at inoculation site) |
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Dysphagia (esophageal webs) Glossitis Iron deficiency anemia |
Plummer-Vinson syndrome (may progress to esophageal SCC) |
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Elastic skin Hypermobility of joints incr. bleeding deficiency |
Ehlers-Danlos syndrome (collagen V defect, vascular subtype: collagen III defect) |
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Enlarged, hard left supraclavicular node |
Virchow node (abdominal metastasis) |
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Episodic vertigo Tinnitus Hearing loss |
Meniere disease |
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Erythroderma Lymphadenopathy Hepatosplenomegaly Atypical T cells |
Mycosis fungoides (cut. T-cell lymphoma) Sezary syndrome (mycosis fungoides + malignant T cells in blood) |
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Facial muscle spasm upon tapping |
Chvostek sign (hypocalcemia) |
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Fever Chills Headache Myalgia Antibiotic treatment for syphilis |
Jarisch-Herxheimer reaction (rapid lysis of spirochetes results in endotoxin release) |
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Fever Cough Conjuctivitis Coryza (nasal mucosa irritation) Diffuse rash |
Measles |
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Fibrous plaques in soft tissue of penis with abnormal curvature |
Peyronie disease (connective tissue disorder) |
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Golden brown rings around cornea |
Kayser-Fleischer rings (Cu accumulation from Wilson disease) |
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Gout Intellectual disability Self-mutilating behavior in a boy |
Lesch-Nyhan syndrome (HGPRT deficiency, Xr) |
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Hamartomatous GI polyps Hyperpigmentation of mouth, hands, feet, genitalia |
Peutz-Jeghers syndrome (inherited, benign polyposis - can cause bowel obstruction, incr. GI cancer risk) |
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Hepatosplenomegaly Pancytopenia Osteoporosis Asceptic necrosis of femur Bone crises |
Gaucher disease (glucocerebrosidase deficiency) |
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Hereditary nephritis Sensorineural hearing loss Cataracts |
Alport syndrome (collagen IV mutation) |
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Hyperphagia Hypersexuality Hyperorality Hyperdocility |
Kluver-Bucy syndrome (bilateral amygdala lesion) |
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Hypoxemia Polycythemia Hypercapnia |
"blue bloater" (chronic bronchitis - hyperplasia of mucosa) |
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Indurated, ulcerated genital lesion Painful w/ exudate |
chancroid (Haemophilus ducreyi)
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Cherry red spot on macula Hepatosplenomegaly Neurodegeneration |
Niemann-Pick disease (genetic sphingomyelinase deficiency) |
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Infant Cleft lip/palate Microcephaly or holoprosencephaly Polydactyly Cutis aplasia |
Patau syndrome (trisomy 13) |
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Infant Hypoglycemia Hepatomegaly |
Cori disease: debranching enzyme deficiency Von Gierke: G6P deficiency (more severe) |
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Infant Microcephaly Rocker bottom feet Clenched hands Structural heart defect |
Edwards syndrome (trisomy 18) |
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Jaundice Palpable distended non-tender gallbladder |
Courvoisier sign (distal obstruction of biliary tree) |
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Large rash w/ bull's eye appearance |
Erythema chronicum migrans (Ixodes bite, Borrelia, Lyme disease) |
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Lucid interval after traumatic brain injury |
Epidural hematoma (middle meningeal artery rupture) |
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Male child Recurrent infections No mature B cells |
Bruton disease (X-linked agammaglobulinemia) |
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Mucosal bleeding Prolonged bleeding time |
Glanzmann thrombasthenia (defect in platelet aggregation due to lack GpIIb/IIIa) |
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Muffled heart sounds Distended neck veins Hypotension |
Cardiac tamponade (Beck triad) |
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Multiple colon polyps Osteomas/soft tissue tumors Impacted/supernumerary teeth |
Gardner syndrome (subtype of FAP) |
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Myopathy (infantile hypertrophic cardiomyopathy) Exercise intolerance |
Pompe disease (lysosomal a-1,4-glucosidase deficiency) |
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Neonate w/ difficult birth Arm paralysis |
Erb-Duchenne palsy ("waiter's tip", superior trunk C5-C5) |
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No lactation postpartum Absent menstruation Cold intolerance |
Sheehan syndrome (pituitary infarction) |
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Nystagmus Intention tremor Scanning speech Bilateral internuclear ophthalmoplegia |
Multiple sclerosis |
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Painful blue fingers/toes Hemolytic anemia |
Cold agglutinin disease (mycoplasma pneumoniae, infectious mononucleosis, CLL) |
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Painful, raised red lesions on pad of fingers and toes |
Osler nodes (infective endocarditis, immune complex deposition) |
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Painless erythematous lesions on palms and soles |
Janeway lesions (infective endocarditis, septic emboli, microabscesses) |
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Palpable purpura on buttocks and legs Joint pain Abdominal pain (child) Hematuria |
Henoch-Schonlein purpura (IgA vasculitis affecting skin and kidneys) |
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Pituitary tumor Parathyroid tumors Pancreatic tumor |
MEN1 Syndrome (AD) |
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Periorbital or peripheral edema Proteinuria Hypoalbuminemia Hypercholesterolemia |
Nephrotic syndrome |
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Pink complexion Dyspnea Hyperventilation |
"pink puffer" emphysema alpha1-antitrypsin deficiency (panacinar) |
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Polyuria Renal tubular acidosis, type II Growth failure Electrolyte imbalances Hypophosphatemic rickets |
Fanconi symdrome (multiple combined dysfunction of PCT) |
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Pruritic Purple Polygonal planar papules Plaques |
Lichen planus |
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Pupil accommodates but doesn't react |
Argyll Robertson pupil (neurosyphilis) |
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Rash on palms and soles |
Coxsackie A Secondary Syphilis Rocky Mountain Spotted Fever |
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Recurrent cold (noninflamed) abscesses Unusual eczema High serum IgE |
Hyper IgE syndrome (Job syndrome: neutrophil chemotaxis [IFN] abnormality) |
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Red currant jelly sputum Alcoholic or diabetic |
Klebsiella pneumoniae pneumonia |
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Red currant jelly diarrhea |
Acute mesenteric ischemia (adults) Intussception (children) |
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Red, itchy, swollen rash of nipple |
Paget disease of the breast (sign of underlying disease) |
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Strawberry tongue |
Scarlet fever
Kawasaki disease |
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Streak ovaries Congenital heart disease Horseshoe kidney Cystic hygroma at birth Short stature Webbed neck Lymphedema |
Turner syndrome (45,X) |
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Swollen gums Mucosal bleeding Poor wound healing Petechiae |
Scurvy (can't hydroxylate proline/lysine for collagen synthesis) |
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Swollen Hard Painful finger joints |
Osteoarthritis (Bouchard nodes: ostephytes on PIP) (Heberden nodes: DIP) |
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Telangiectasias Recurrent epistaxis Skin discoloration AV Malformation GI bleeding Hematuria |
Osler-Weber-Rendu syndrome |
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Medullary Thyroid tumor Parathyroid tumors Pheochromocytomas |
MEN 2A (AD: RET mutation) |
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Medullary Thyroid tumor Pheochromocytomas Ganglioneuromatosis |
MEN 2B (AD: RET mutation) |
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Urethritis Conjuctivitis Arthritis Male |
Reactive arthritis (HLA-B27) |
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Vascular birthmark of face (port wine stain) |
Nevus flammeus (benign, assoc. w/ Sturge-Weber syndrome) |
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Weight loss Diarrhea Fever Adenopathy Arthritis |
Whipple disease (Tropheryma whipplei) (PAS+ macrophages, non-acid fast gram + bacilli) |
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Worst headache of my life |
Subarachnoid hemorrhage |
