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102 Cards in this Set
- Front
- Back
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Abdominal pain, ascites, hepatomegaly
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Budd Chiari syndrome (posthepatic venous thrombosis)
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Achilles tendon xanthoma
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familial hypercholesterolemia ( decreased LDL receptor signaling)
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Adrenal hemorrhage, hypotension, DIC
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Waterhouse-Frederichsen sydrome (meningcoccemia)
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Arachnodactylyl, lens dislocation, aortic dissection, hyperflexible joints
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Marfan's syndrome (fibrillin defect)
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Athlete with polycythemia
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erythropotein injection
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Back pain, fever, night sweats, weight loss
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Pott's disease (TB in vertebrae)
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Bilateral hilar adenopathy, uveitis
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Sarcoidosis
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Blue sclera
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(Osteogenesis type I (type I collagen defect)
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Bluish line on gingiva
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Burton's line (lead poisoning)
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Bone pain, bone enlargement, arthritis
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Paget's dz of bone (increased osteoblastic and osteoclastic activity)
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Bounding pulses, diastolic heart murmur, head bobbing
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Aortic regurgitation
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Butterfly rash and raynaud's phenomenon in a young female
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systemic lupus erythematous
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Cafe-au-lait spots, lisch nodules (iris hamartoma)
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NF type I (+ pheochromo, optic gliomas)
NF type II (bilateral acoustic neuromas) |
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Cafe-Au laite spots, polyostotic fibrous dysplasia, precocious puberty
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Mcune-Albright syndrome (mosaic G- protein signaling)
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Calf pseudohypertophy
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Muscular dystrophy (Duchenne's usually) XR deletion of dystrophin gene
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Cherry-red spot on macula
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Tay Sach's (ganglioside) or Niemann Pick (spingomylein accumulation), central retinal artery occlusion
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Chest pain, pericardia effusion/friction rub, persistent fever following MI
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Dressler's syndrome (autoimmune post MI fibrinous pericarditis, 1-12 weeks after acute episode)
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Child uses arms to stand up from squat
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Gower's sign (duchenne muscular dystrophy)
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Child with fever develops red rash on face that spreads to body
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Slapped cheeks disease; erythema infectiosum...B19
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Chorea, dementia, caudate degeneration
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Hungtingdon's disease (AD CAG repeat expansion)
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Chronic exercise intloerance with myalgia, fatigue, painful cramps, myoglobinuria
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McArdle's disease (muscle glycogen phosphorylase deficiency)
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Conjugate lateral gaze palsy, horizontal diplopia
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Internuclear opthalmoplegia, damage to MLF
Bilateral: MS Unilateral: stroke |
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Continuous machine-like murmur
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PDA (close with indomethacin; open with misoprostol)
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Dark purple skin, mouth nodules
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Kaposi's sarcoma; AIDS, HHV8
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Deep labored breathing/hyperventilation
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Kussmaul, (DKA)
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Dermatitis, Dementia, diarrhea
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pellagra (niacin B3 deficiency)
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Dilated cardiomyopathy, edema, polyneuropathy
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Wet beriberi (thiamine B1 defiency)
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dry mouth and eyes, arthritis
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Sjogrens (anti Ro and anti-La)
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Dysphagia, glossitis, IDA
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plummer vinson syndrome (may prgoress to esophageal squamous cell carcinoma)
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elastic skin
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Ehler-danlos syndrome (type III collagen defect)
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enlarge, hard left supraclavicular node
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virchow's node (abdominal metastasis)
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Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells
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Sezary syndrome (cutaneous T cell lymphoma), or mycosis fungoides
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facial muscle spasm upon tapping
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Chvostek's sign (hypocalcemia)
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Fat, female, forty, and fertile
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Acute cholelithiasis (bile duct blockage)
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fever, chills, headache, myalgia following antibiotic treatment for syphylis
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Jarisch-herxheimer reaction (rapid lysis of spirochetes results in toxin release)
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fever, cough, conjunctivitis, coryza, diffuse rash
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Measles (morbillivirus)
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Fever, night sweats, weight loss
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B symptoms (lymphoma)
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fibrous plaques in soft tissue of penis
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Peyronie's disease (connective tissue disorder)
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gout, mental retardation, self-mutilating behavior in boy
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Lesch-myhan syndrome (HGPRT defiency, XR)
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green-yellow rings around peripheral cornea
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Kayer-fleischer rings (Copper accum from wilson's disease)
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hamartomatous GI polyps, hyperpigmentation of mouth/feet/hands
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Peutz-jeghers syndrome
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hepatosplenomegaly, osteoporosis, neurologic symptoms
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Gaucher's disease (glucocerebrosidase defiency)
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hereditary nephritis, sensorineural hearing loss, cataracts
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Alport syndrome (defect in collagen type IV)
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hyperphagia, hypersexuality, hyperorality, hyperdocility,
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Kluver Bucy (bilateral amygdala lesion)
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Hypertension hypokalemia metabolic alkalosis
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Conn's syndrome (hyperaldosteronism)
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hyporeflexia, hypotonia, atrophy
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LMN lesion
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hypoxemia, polycythemia, hypercapnia
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Chronic bronchitis (hyperplasia of mucus cells)
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infant with failure to thrive, hepatosplenomegaly, neurodegeneration
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Niemann Pick (sphingomyelinase deficiency)
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hypoglycemia, failure to thrive, hepatomegaly
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Cori's disease (deficiency of debranching enzyme)
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infant with microcephaly, rocker-bottom feet, clenched hands, structural heart defect
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Edwards syndrome (tri 18)
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keratin pearls on skin biopsy
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squamous cell carcinoma
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large rash with bull-eyes appearance
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erythema chronicum migrans (borrelia from Ixodes)
Ixodes also vector for babesia |
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lucid interval after traumatic brain injury
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epidural hematoma (middle meningeal)
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male child, recurrent infections, no mature B cells
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Bruton's agammaglobulinemia (XR)
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Mucosal bleeding, prolonged bleeding time
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Glanzmann's thrombasthenia (GpIIB/IIIa defect)
*this sounds like von willebrands disease too? |
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multiple colon polyps, osteomas/soft tissue tumors, impacted/supernumerary teeth
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Gardner's syndrome (FAP subtype)
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Myopathy (infantile hypertrophic caridomyopathy), exercise intolerance
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Pompe's disease (lysomal alpha-1,4 glucosidase defiency)
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necrotizing vasculitis (lungs) and necrotizing glumerulonephritis
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Wegner's (c-ANCA) and Goodpastures(anti-BM)
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neonates with arm paralysis following difficult birth
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Erb-Duchenne (superior trunk (c5-6) injury, waiter's tip)
associated with maternal diabetes..difficult birth |
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no lactation postpartum, absent menstruation, cold intolerance
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Sheehan's syndrome (pituitary infarction
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nystagmus, intention tremor, scanning speech, bilateral internuclear opthalmoplegia
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multiple sclerosis
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oscillating slow/fast breathing
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cheyne-stokes respirations (central apnea in CHF or increased cranial pressure)
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painful blue finger/toes, hemolytic anemia
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gold agglutin disease (m pneumo or infectious mononucleosis causing autoimmune hemolytic anemia)
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painful,pale, cold fingers
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raynauds syndrome
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painful red lesions on palms and soles
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Osler's nodes (endocarditis)
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painless erythematous lesions on palms and soles
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Janeway lesions (endocarditis)
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painless jaundice
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cancer of the pancreatic head obstructing bile duct
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palpable purpura on buttocks, joint pain, abdominal pain
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henloch schonlein purpura (IgA vasculitis affecting skin and kidneys)
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pancreatic, pituitary, parathyroid tumors
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MEN I (AD)
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pink complexion, dyspnea, hyperventilation
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emphysema (centriacinar-smoking, panacinar- alpha 1 antitrypsin)
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polyuria, acidosis, growth failure, electrolyte imbalances
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Fanconi's syndrome (proximal tubular readsorption defect)
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ptosis, miosis, anhidrosis
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Horner's syndrome
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pupil accomodates but doesn't react
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Argyll Robertson pupil (neurosyphilis)
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rapidly progressive leg weakness that ascends (following URI)
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Guillain barre- demyelinating disease that ascends ( campylobacter usually associated)
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Rash on palms and soles
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coxsackie A, secondary syphilis, rocky mountain spotted fever
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recurrent colds, unusual eczema, high serum IgE
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Job's/hyper IgE syndrome (neutrophil chemotaxis defiency)
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red current jelly sputum
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Klebsiella
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red, itchy, swollen rash of nipple/aerola
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Paget's dz of breast (represents underlying neoplasm)
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red urine in morning
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paroxysmal nocturnal hemoglobinuria
(defect in delay accelerating factor, which destabilizes C3 and C5 convertase binding to RBC membrane) |
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renal cell carcinoma, hemangioblastomas, angiomatosis, pheochromocytoma
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Von-hippel-lindau dz (dominant tumor suppresor gene mutaiton AD)
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resting tremor, rigidity, akinesia, postural instability
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parkinson's (nigrostriatal dopamine depletion)
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retinal hemorrhage with pale center
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Roth's spots (bacterial endocarditis)
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severe jaundice in neonate
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Crigler-najjar syndrome (congenital unconjugated hyperbilirubinemia, defect in UDP glucoronyl transferase deficiency)
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short stature, increased incidence of tumors/leukemia, aplastic anemia
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Fanconi's anemia (genetic loss of DNA crosslink repair; often progress to AML)
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situs inversus, chronic sinusitis, bronchiectasis, infertility
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Kartagener (dynein arm defect in cilia)
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skin hyperpigementation
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Addison's dz (primary adrenocortical defiency, icnrease acth and MSH production)
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slow, progressive muscle weakness in boys
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Becker's dystrophy (XR, less severe than Duchenne's)
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small irregular red spots on buccal/lingual mucosa with blue-white centers
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koplik spots (measles; rubeola virus)
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Smooth, flat, moist white lesions on genitals
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Condyloma lata (secondary syphilis)
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spliter hemorrhages in fingernails
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bacterial endocarditis
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streak ovaries, congenital heart disease (coarc), horseshoe kidney, cystic hygroma at birth
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Turner syndrome
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swollen gums, mucous bleeding, poor wound healing, spots on skin
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scurvy (vit c defiency, needed to hydroxylate proline and lysine in collagen syn)
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swollen hard painful finger joints
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osteoarthritis (osteophytes on PIP (bouchards) and DIP (heberdeens)
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systolic ejection murmur
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aortic valve stenosis
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thyroid tumors, pheochromocytoma, ganglionneuromatosis
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MEN 2B (ret mutation, marfinoid habitus)
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unilateral facial droopign involving forehead
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Bell's palsy (LMN CN VII and palsy)
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urethritis, conjunctivitis, arthritis in male
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Reactive arthritis assoc with HLA-B27
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vascular birthmark (port-wine stain)
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Hemangioma (benign, but associated with sturge-weber)
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vomitting blood following esophageal lacerations
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mallory weiss syndrome
boerrhave's is full thickness perforation* |
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"waxy" casts with very low urine flow
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chronic ESRD
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weight loss, diarrhea, arthritis, fever, adenopathy
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Whipple disease
PAS stain used for dx |
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worst headache of my life
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subarachnoid hemorrhage (bloody or yellow spinal tap)
rupture of aneurysm (usually marfan's ehlers-danlos, ADPKD) or an AVM |
