Class Mode Of Action Spectrum

Front 1

natural penicillins

Back 1

inhibit cellwall synthesis
Strep A, B, C, G, Neisseria meningitidis, trepenoma pallidum, clostridium

Front 2

penicllinnase-resistant

Back 2

same with side chain that prevents the opening of penicillins
penicillin resistant staff

Front 3

extended spectrum penicllin

Back 3

negative bacilli
strep A<B<CandG
enterococcus
listeria mono\cytigenes
proteus mirabilis
streptococcus pneumonia

Front 4

carbpxypenicillins
ticarcillin

Back 4

P auruginosa
gram negative

Front 5

ureidopenicllin
pirpacil

Back 5

gram negaitve klebsiella activity

Front 6

pencillin plus blactamase inhibitor
ampicillin sulbactam
ticarcillin
piperacillin

Back 6

pseudomonal infecctions

Front 7

cephalosporins

Back 7

inhibit bacterial cell wall
gram positive strep staph
gram negative proteus, ecoki, klebsiella

Front 8

second gen ceph

Back 8

gram + strep, staph
gram - H flu, enterobacter, neisseria
B. fragilis
abdominal infections

Front 9

third gen cep halo

Back 9

enterobacter, serratia, citrobacter
ceftazidime
gram + less
Gram negative Pseudomanas

Front 10

fourth gen cephalosp

Back 10

gram + staph, strep
gram neg including pseudomonas

Front 11

fifth gen cephalosp

Back 11

gram positive and gram negative
Staph. aureus, pyogenes, S. agalactiae
gram neg E.col, K. pneumonia, k. oxytoca
gram positive bacteria S. pneumonia, S. aureus
gram negative: H. influenza, K. pneumoniae, K. oxytoca, E.coli

Front 12

macrolides

Back 12

50 s ribosome
staph strep, atypical, h. flu, moraxella

Front 13

clindamycin

Back 13

50 s staph step
B. fragilis, peptococcus, peptostreptococcus

Front 14

metronidazole

Back 14

protozoal organisms anaerobic bacteria
C. difficile
inhibits a reduction reaction required for anaerobic organism growth

Front 15

doxycycline

Back 15

30s gram positive S. pneumoniae
gram - N. meningitidis, E.coli, M. catarrhalis, H. flu
atypical riskettsia, borrelia, chlamydia

Front 16

sulfamethoxazole/trimethoprim

Back 16

good gram + and -
infibits folic acid synthesis

Front 17

rifampin

Back 17

inhbits bacterial DNA dependent RNA polymerase
N. meningitis, H. flu, S. aureus, TB

Front 18

aminoglycosides

Back 18

inhibit of bacterial protein syntheism
gram + in conjucion with a beta lactam
gram - bacilli

Front 19

vancomycin

Back 19

inhibition of cell wall synthesis, time dependent activity
C. difficile colitis

Front 20

quinolones

Back 20

inhibits DN gyrase and topoisomerase
gram + cocci, gram - cocci gram - bacilli

Front 21

carbapenems

Back 21

bind to bacterial peptides and PBP, inhibit cell wall synthesis
gram + cocci gram - bacilli, aneorobes

Front 22

monobactam

Back 22

bind to transpeptidase and PBP's inhibition of cell wal synthesis
gram - coverage only

Front 23

qinupristin/dalfopristin

Back 23

act on bacterial ribosomes to inhibit protein synthesis
VRE MRSA

Front 24

linezolid

Back 24

bacterial ribosomes ti inhibit translocatioVRE, MRSA

Front 25

daptomycin

Back 25

rapid depolarization of bacterial membrane resulting incell death

Front 26

telithromycin

Back 26

binds to the 50 s subunit of bacterial ribosomes
s. pneumoniae and s. pyogenes, good activity against H. flu and M. catarrhalis

Front 27

amphotericin B

Back 27

binds to ergosterol in fungal call membrane altering permeability and causing call leakage
aspergillus species, candida species and crypococcus species

Front 28

fluconazol

Back 28

intereferes with cytochrome P450 activity, cesreasing ergosterol synthesis and inhibiting cell membrane formation
candidiasis and cryptococcal meningitis

Front 29

caspofungin

Back 29

inhibits syntheis of beta(1,3)-D-glucan an essential component of the cell wall of susceptable fungi
aspergillus candida andidemai