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40 Cards in this Set

  • Front
  • Back
abnomalities of menstruation before manarche:
newborns: withdrawal bleeding
before menarche: form malignancy, trauma, sexual abuse, foreign body, urinary tract problems, irritation
50% of cases involve lesions of genital tract
abnormalities of menstruation childbearing years
by 18-21 should be normal, hypothalamic-pituitary axis has matured
may be from pregnancy and preg related conditions
may be meds, other medical problems, IUD, GYN disorders
evaluations of abnormal preg
first rule out pregnancy then consider, coagulopathy, pelvic lesions, malignancy, thyroid, dysfunctional uterine bleeding
diagnostic tests of abnormal bleeding in childbearing years
hCG, CBC
plt
bleeding time
liver function
thyroid
pap smear
eval of abnormal bleeding after menopause
dx and tx
CANCER UNTIL CONSIDERED OTHERWISE
bengin causes: atrophic vaginitis, polyps, endometrial hyperplasia
tx: dilation and curettage, biopsy
eval of abnormal bleeding in perimenopause
rule out endometrial cancer and pregnancy
tx of abnormal bleeding
-stabilize pt
-high dose estrogen to support endometrium and stop bleeding, if successful follow with low dose estrogen and progestin
-dilation and curretage if estrogen fails
-OCs for mild bleeding
-hysterectomy if necessary
Dysfuntional Uterine Bleeding (DUB)
abnormal unterine bleeding in women between menarche and menopause and cannot be attributed to meds, blood disorders, systemic disease, trauma, uterine neoplasms or preg
-commonly seem around menarche and meopause
-teens: from immaturatiy of the hypothalamic-pituitary system
-perimenopausal: may be from declining functioning of ovary
DUB dx
exclusion, rule out everything else
DUB tx
-OC's (dont give to smokers >35yo)
-cyclic progestins: expected to bleed if they don't bleed then you know they don't have enough estrogen
-hysterectomy last resort
sonohysterogrpahy
put saline into uterine cavity and look with U/S to evaluate for uterine or endometrial pathology
amenorrhea
absence of menstrual bleeding
primary amenorrhea
no spontaneous uterine bleeding by age 15 with normal secondary sex characteristics or 13 yo with abnormal secondary sex characteristics
secondary amenorrhea
absence of menstrual periods for 3 cycles or 6 consecutive months in a women who had periods previously
causes of amenorrhea
1. preg
2. hypothalamic defects
3. pituitary defects
4. ovarian/ovulatory dysfunction
5. uterine cuases
6. others
congenital deficiency of GnRH
cause of amenorrhea
- no GNRH secretion
- ovulation doesn occur
male:female 5:1
defect of GnRH transport
cause of amenorrhea
-hypothalamic lesions
-benign brain tumor
-preventys flow from hypothal to pituitary
defects of GnRH pulse production
cause of amenorrhea
-not released at appropriate time
-anorexia
-extreme wt lose
-severe stress
-athletics
congential absence of pituitary
cause of amenorrhea
rare-lethal usually
pituitary defects: cause of amenorrhea
1. Sheehan's Syndrome: pituitary necrosis from hemorrage and sever hypotension
2. Iron deposition in pituitary: pts with very high iron levels
PCOS
cause of amenorrhea
Turners syndrome
cause of amenorrhea
-abnormal X chromosome
-webbed neck, increase carrying angle (cant put hands at side)
Premature Ovarina Failure
cause of amenorrhea
-depletion of ova before age 40
congenital absence or malformation of uterus
cause of amenorrhea
-unresponsive or atrophic endometrium
imperforated hymen
cause of amenorrhea
lab findings of amenorrhea
-FHS and LH
-testosterone
-thyroid studies
-preg test
-MRI/Ct of hypothal/pituitary
-genetic eval
-U/S
treatment of primary amenhorrea
depends on cause
-turners syndrome: estrogen
-pituitary tumors: bromocriptine (inhibits prolactin secretion), srugery, radiation
-support
secondary amenhorrea: causes
-preg most common cause
-ovarian failure or dysfunction
-stoping OCs
-hypothal/pituitary causes
-obesity
-cushings disease (adrenal overactivity)
-menopause
secondary amenhorrea: PE
-androgen excess
-breast exam: galactorrhea (prolactinc excess)
-estrogen deficiency
work up tailored to H&P
tx of secondary amenhorrea
-hormone replacement therapy, tx for tumores, systemic disease, support
primary dysmenorrhea
cause
ssx
17-22 yo
no readily identified cause
-uterine contractions with ischemia
-cramping, lower abdomen to things and back, pain with altered bowel habits, nausea, vomiting, fatigue, dizziness
-PE usually normal
primary dysmen tx
-NSAIDs (motrin)
-OCs
-topical heat
-diet low in fat
-if not response consider seconardy
secondary dysmenorrhea
-painful menstruation due to some underlying cause
-starts in 30s-40s
-during, before, or after menses
-ssx: dysparuenia, infertility, or abnormal uterine bleeding
-do pelvic exam
causes of secondary dysmenorrhea
1. Endometriosis
2. Fibroids. Adenomyosis
3. Pelvic congestion (dull ache, diminished with menses)
4. IUD
5. polyps
6. adhesions
7 cervical stricture or stenosis
eval of secondary dysmenorrhea
-cervical cx to rule our STI
-WBC
-hCG
-Pelvic US
-laparoscopy
tx of secondary dysmenorrhea
-treat underlying disease
-NSAIDs
- OCs
premenstural syndrome (PMS)
emotional and physical symptoms in luteal phase of menstural cycle
80% of women have it
5% have severe symptoms (Premenstural dysphoric disorder PMDD)
-exact cause not known
theories of PMS
1. homonal basis
2. ovarian function involved
3. genetic factors
4. serotonin deficicncy
ssx of PMS
1. depressed mood
2. anxiety
3. emotional liability
4. irritability
5. decreased interest in activities
6. fatigue
7. sleep disturbances
8. ab pain, breast tenderness, bloating, wt. gain, edema, headache
dx and tx of PMS
Dx: nothing specific, symptoms diary for 2-3 periods
Tx: reassurance, rest, exercise, low sodium, caffeine, chocolate and alcohol
-midol, vitamins, mid diuretics, anti-anxiety meds, SSRIs, GnRH agonists, NSIDs
**OCs not reccommended