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40 Cards in this Set
- Front
- Back
abnomalities of menstruation before manarche:
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newborns: withdrawal bleeding
before menarche: form malignancy, trauma, sexual abuse, foreign body, urinary tract problems, irritation 50% of cases involve lesions of genital tract |
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abnormalities of menstruation childbearing years
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by 18-21 should be normal, hypothalamic-pituitary axis has matured
may be from pregnancy and preg related conditions may be meds, other medical problems, IUD, GYN disorders |
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evaluations of abnormal preg
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first rule out pregnancy then consider, coagulopathy, pelvic lesions, malignancy, thyroid, dysfunctional uterine bleeding
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diagnostic tests of abnormal bleeding in childbearing years
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hCG, CBC
plt bleeding time liver function thyroid pap smear |
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eval of abnormal bleeding after menopause
dx and tx |
CANCER UNTIL CONSIDERED OTHERWISE
bengin causes: atrophic vaginitis, polyps, endometrial hyperplasia tx: dilation and curettage, biopsy |
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eval of abnormal bleeding in perimenopause
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rule out endometrial cancer and pregnancy
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tx of abnormal bleeding
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-stabilize pt
-high dose estrogen to support endometrium and stop bleeding, if successful follow with low dose estrogen and progestin -dilation and curretage if estrogen fails -OCs for mild bleeding -hysterectomy if necessary |
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Dysfuntional Uterine Bleeding (DUB)
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abnormal unterine bleeding in women between menarche and menopause and cannot be attributed to meds, blood disorders, systemic disease, trauma, uterine neoplasms or preg
-commonly seem around menarche and meopause -teens: from immaturatiy of the hypothalamic-pituitary system -perimenopausal: may be from declining functioning of ovary |
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DUB dx
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exclusion, rule out everything else
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DUB tx
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-OC's (dont give to smokers >35yo)
-cyclic progestins: expected to bleed if they don't bleed then you know they don't have enough estrogen -hysterectomy last resort |
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sonohysterogrpahy
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put saline into uterine cavity and look with U/S to evaluate for uterine or endometrial pathology
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amenorrhea
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absence of menstrual bleeding
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primary amenorrhea
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no spontaneous uterine bleeding by age 15 with normal secondary sex characteristics or 13 yo with abnormal secondary sex characteristics
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secondary amenorrhea
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absence of menstrual periods for 3 cycles or 6 consecutive months in a women who had periods previously
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causes of amenorrhea
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1. preg
2. hypothalamic defects 3. pituitary defects 4. ovarian/ovulatory dysfunction 5. uterine cuases 6. others |
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congenital deficiency of GnRH
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cause of amenorrhea
- no GNRH secretion - ovulation doesn occur male:female 5:1 |
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defect of GnRH transport
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cause of amenorrhea
-hypothalamic lesions -benign brain tumor -preventys flow from hypothal to pituitary |
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defects of GnRH pulse production
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cause of amenorrhea
-not released at appropriate time -anorexia -extreme wt lose -severe stress -athletics |
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congential absence of pituitary
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cause of amenorrhea
rare-lethal usually |
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pituitary defects: cause of amenorrhea
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1. Sheehan's Syndrome: pituitary necrosis from hemorrage and sever hypotension
2. Iron deposition in pituitary: pts with very high iron levels |
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PCOS
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cause of amenorrhea
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Turners syndrome
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cause of amenorrhea
-abnormal X chromosome -webbed neck, increase carrying angle (cant put hands at side) |
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Premature Ovarina Failure
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cause of amenorrhea
-depletion of ova before age 40 |
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congenital absence or malformation of uterus
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cause of amenorrhea
-unresponsive or atrophic endometrium |
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imperforated hymen
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cause of amenorrhea
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lab findings of amenorrhea
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-FHS and LH
-testosterone -thyroid studies -preg test -MRI/Ct of hypothal/pituitary -genetic eval -U/S |
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treatment of primary amenhorrea
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depends on cause
-turners syndrome: estrogen -pituitary tumors: bromocriptine (inhibits prolactin secretion), srugery, radiation -support |
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secondary amenhorrea: causes
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-preg most common cause
-ovarian failure or dysfunction -stoping OCs -hypothal/pituitary causes -obesity -cushings disease (adrenal overactivity) -menopause |
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secondary amenhorrea: PE
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-androgen excess
-breast exam: galactorrhea (prolactinc excess) -estrogen deficiency work up tailored to H&P |
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tx of secondary amenhorrea
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-hormone replacement therapy, tx for tumores, systemic disease, support
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primary dysmenorrhea
cause ssx |
17-22 yo
no readily identified cause -uterine contractions with ischemia -cramping, lower abdomen to things and back, pain with altered bowel habits, nausea, vomiting, fatigue, dizziness -PE usually normal |
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primary dysmen tx
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-NSAIDs (motrin)
-OCs -topical heat -diet low in fat -if not response consider seconardy |
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secondary dysmenorrhea
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-painful menstruation due to some underlying cause
-starts in 30s-40s -during, before, or after menses -ssx: dysparuenia, infertility, or abnormal uterine bleeding -do pelvic exam |
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causes of secondary dysmenorrhea
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1. Endometriosis
2. Fibroids. Adenomyosis 3. Pelvic congestion (dull ache, diminished with menses) 4. IUD 5. polyps 6. adhesions 7 cervical stricture or stenosis |
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eval of secondary dysmenorrhea
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-cervical cx to rule our STI
-WBC -hCG -Pelvic US -laparoscopy |
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tx of secondary dysmenorrhea
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-treat underlying disease
-NSAIDs - OCs |
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premenstural syndrome (PMS)
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emotional and physical symptoms in luteal phase of menstural cycle
80% of women have it 5% have severe symptoms (Premenstural dysphoric disorder PMDD) -exact cause not known |
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theories of PMS
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1. homonal basis
2. ovarian function involved 3. genetic factors 4. serotonin deficicncy |
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ssx of PMS
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1. depressed mood
2. anxiety 3. emotional liability 4. irritability 5. decreased interest in activities 6. fatigue 7. sleep disturbances 8. ab pain, breast tenderness, bloating, wt. gain, edema, headache |
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dx and tx of PMS
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Dx: nothing specific, symptoms diary for 2-3 periods
Tx: reassurance, rest, exercise, low sodium, caffeine, chocolate and alcohol -midol, vitamins, mid diuretics, anti-anxiety meds, SSRIs, GnRH agonists, NSIDs **OCs not reccommended |