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21 Cards in this Set
- Front
- Back
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Complex of DNA and proteins functions to compact DNA |
Chromatin |
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This histone is the linker of DNA |
H1 |
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High compacted, inactive |
Heterochromatin |
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Less dense, active. Transcription allowed |
Euchromatin |
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Cap at the end of chromosomes made of repetitive sequences |
Telomere |
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mRNA is produced by ____ and functions to |
RNA Pol II, encodes AA sequence |
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tRNA is produced by ___ and functions to |
RNA Pol III,Read mRNA and transfer AA in the ribosome |
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rRNA is produced by ____ and functions to |
RNA Pol I, forms ribosomes |
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Methylated DNA leads to what structure of chromatin |
Open |
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Unmethylated DNA leads to what structure of chromatin |
Closed |
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Attachment of functional groups to AA after translation that changes chemical nature of the AA and behavior |
Post-translational mods |
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Acetylation ____ and ____ chromatin |
Opens and activates |
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Deacetylation ____ and ____ chromatin |
Closed and inactivates |
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Acetylation of histones does what to charged AAs |
Decreases positive charges |
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Acetylation of histones does what to gene expression |
Increases |
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Molecules that add mods to AA or nucleotides |
Writers |
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Read and bind to modified AA or nucleotide |
Reader |
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Removes mods from AAs |
Erasers |
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Methylation has what effect on genes? |
Repression |
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Which Histone Deacetylase requires NAD+ instead of Zinc? |
Class 3 |
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Master regulator of metabolism |
Sirtuins |
