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71 Cards in this Set

  • Front
  • Back
Myofibril
make up the contractile components in muscles. The smallest complete contractile system. Densely packed cells with contractile proteins, energy storage and signaling mechanisms.
Muscle Fiber
each fiber contains hundreds or even thousands of myofibrils. Each individual fiber consists of a membrane (sarcolemma) and can be further broken down into myofibrils.
Fasciculus
Muscle fibers are grouped into bundles of up to 150 fibers called fasciculus.
Muscle
Contains smaller wrapped packages known as fasciculus. Each muscle belly is made up of muscle cells or fibers.
Belly Muscle
a term used to describe the large mass of muscle that powers movement.
Contractile property of Muscle Tissue
allows it to become short and thick in response to nerve impulse and then to relax once impulse removed
Muscle Cells Elongated
resemble fibers such as those in rope
Muscle tissue
constructed of bundles of these fibers, each approximately the diameter of a human hair
3 basic muscle types
Skeletal, cardiac, smooth

microfilaments

Narrow, tube like cell structure composed of a protein similar to actin, occurring singly and in bundles, involved in cytoplasmic movement & changes in cell shape. Movement that causes muscles to contract and shorten.

Smooth (Visceral) Muscle
not striated, spindle-shaped cells, single nucleus, involuntary, found within certain hallow organs, blood vessels, respiratory airways, Ability to expand and contract essential to internal processes of body (digestion/regulation of blood pressure)
Cardiac Muscles
striated, usually has a single nucleus, branching cells, joined to another muscle cell at an intercalated disc, involuntary, found only in the walls of the heart, Contraction of cardiac muscle squeezes blood out of chambers of the heart, causing blood to circulate through the body, Fibers shorter; receive richer supply of blood than any other muscle in body, Does not regenerate; damage often leads to tissue death
Skeletal muscles
mostly attached by tendons to bones. Some muscles attach directly to bone or soft tissue without tendon, using a broad sheet of connective tissue called an aponeurosis. Cells are multinucleate and striated (visible banding), called voluntary bc movement is controlled by conscious thought. Long & cylindrical. muscle is striated, voluntary muscle that allows movement, stabilizes joints, and helps maintain body temperature
Rules for naming muscles
muscles can be named based on the location, shape, direction of fibers or a combination.
orbicularis oculi
location: encircles eyemuscle origin: frontal, maxilla, & orbitmuscle insertion: eyelidmuscle action: closes eyelid
biceps brachii
location: upper armmuscle origin: scapulamuscle insertion: radiusmuscle action: flexes arm at elbow
triceps brachii
location: posterior upper armmuscle origin: proximal humerus & scapulamuscle insertion: posterior ulnamuscle action: extends arm at elbow
Masseter
location: jaw or mandiblemuscle origin: zygomatic archmuscle insertion: mandiblemuscle action: closes jaw
sternocleidomastoid
location: anterolateral neckmuscle origin: sternum & claviclemuscle insertion: mastoid processmuscle action: flexes and rotates head
Aponeurosis
a broad sheet of connective tissue
Contraction
shortening of a muscle, When muscle stimulated, calcium released from sarcoplasmic reticulum (SR) and allows actin, myosin, & ATP to interact, which causes the contraction
agonist
primary mover; chief muscle causing movement; as muscle contracts bones will move
Point of origin
muscle end attached to stationary bone
Point of insertion
muscle end attached to moving bone
Synergistic
muscles that assists primary movers
Antagonist
muscles cause movement in opposite direction of agonist
All movement
result of contraction of primary movers and relaxation of opposing muscles
Diaphragm
Dome-shaped muscle, primary muscle of breathing, separates abdominal cavity and thoracic cavity, Responsible for performing major work of bringing atmospheric air into lungs, Muscle under both voluntary and involuntary control
rotation
circular movement that occurs around an axis
abduction
to move away from midline of body
adduction
movement toward midline of body
extension
increasing angle between two bones connected at a joint
extensor muscle
Muscle that straightens the joint is
Flexion
opposite of extension, decreasing angle between two bones
flexor
Muscle that bends the joint
epimysium
Typical muscle surrounded by connective tissue, continuous with tendon
fascicles
bundles of muscle fibers inside muscles
perimysium
surrounds fascicles
myofibrils
long organelles inside of muscle cells, made of protein threads arranged in contractile units with two types of protein threads: myosin and actin
Sarcomeres
unit contains two threadlike contractile proteins: myosin and actin, makes up myofibril
myosin
Thick myofilaments made up of protein

actin
THIN ones made up of protein
contraction of muscles
causes the two types of myofilaments to slide toward each other and shorten each sarcomere, and therefore entire muscle. requires temporary connections, or cross-bridges, formed between myosin heads and actin
ATP (adenosine triphosphate)
provides energy to help myosin heads form and break crossbridges with actin
calcium
causes muscles to contract. stored away from actin and myosin in sarcoplasmic reticulum (SR)when muscle is relaxed. When calcium returns to SR, cross-bridges are broken, and the muscle relaxes
sodium ion channels
opens when nervous system tells muscle to contract, signal caused by muscle fiber membrane
sodium ions
flow into muscle fiber, exciting it
Neuromuscular junction
Association site of axon terminal of the motor neuron and muscle
Synaptic cleft
Gap between nerve and muscleNerve and muscle do not make contactArea between nerve and muscle is filled with interstitial fluid
calcium ion
entry causes some synaptic vesicles to release their contents (acetylcholine, a neurotransmitter) by exocytosis

Neurotransmitter
chemical released by nerve upon arrival of nerve impulse in the axon terminal -for skeletal muscle it is ACh
Muscular Fuel
needs fuel in the form of nutrients and oxygen to survive and function, Body stores glycogen in the muscle, where it waits to be converted to useable energy source, When needed, glycogen converted to glucose which releases energy, Muscles with very high demands store fat and use it as energy, Energy release causes heat production; this is why strenuous/prolonged exercises can overheat our bodies, Higher demand muscles have richer blood supply to carry oxygen to muscles giving those muscles a darker color
Vasodilation
enlarging diameter of blood vessel, can lead to decreases in blood pressure due to smooth muscle relaxation in blood vessel
Vasoconstriction
decreasing diameter of blood vessel, Increases blood pressure
sphincter
Special type of smooth muscle found throughout digestive system.muscles act to let materials in and out by contracting and relaxing
Involuntary muscles
do not contract as rapidly as skeletal muscles Receives only moderate blood supply, resulting in poor repair of injured tissue
Myopathy
muscle disease or disorder, Causes include: injury, genetics, nervous system disorders, medication, and cellular abnormalitiesTreatment depends on the cause

Tendinitis/Tendinosis


Degenerative disease leading to breakdown and scarring of tendons
shin splints
Common inflammatory injury of lower leg extensor muscles and surrounding tissues
strains and tears
caused by overstretching tendons or muscles Injuries range from slight overstretch to complete muscle tear or tendon rupture Injuries acute, resulting from trauma, or chronic, resulting from overuse or disease
signs/symptoms of strains and tears
vary on severity of injuryMild strain (no tear of muscle or tendon fibers)Moderate strain (some tearing of muscle or tendon fibers)Severe strain (complete tear of muscle or tendon)
Myalgia
pain or tenderness in muscle
Fibromyalgia Syndrome
Fibromyalgia syndrome (FMS): chronic pain syndrome The cause is unknown and there is no definitive treatment; presently treat with symptom management
Duchenne Muscular Dystrophy
Genetic, incurable myopathy All types of muscle affected (smooth, cardiac, and skeletal)Carried on X chromosome, seen more often in boysDisease courseProgressive disease usually diagnosed around age fourBy age ten, child usually wheelchair-bound; Average life span is 17 yearsDeath usually due to respiratory or cardiac failure, no effective treatment
Myasthenia Gravis
Autoimmune disorder where immune system attacks and destroys large number of acetylcholine receptors at the neuromuscular junctionSigns and symptoms When motor neurons release acetylcholine, muscle cell cannot respondMuscle weakness fluctuates, worsening with activity and improving with rest
Tetanus
Also known as “lockjaw;” caused by untreated bacterial wound infectionBacteria responsible is Clostridium tetani, which lives in soilBacteria release toxin that keeps muscle constantly contracted (“locked”)Prevention possible through vaccinationInitial tetanus series given in childhoodBooster shots given every ten years to adults
Nonsteroidal anti-inflammatory drugs (NSAIDs)
Relieve inflammation, but do not have negative side effects of steroidsExamples: ibuprofen (Advil™), naproxen (Aleve™)
Pain medications
Aspirin and Acetaminophen (Tylenol)
Muscle relaxants
Help muscles rest in order to heal themselvesHelp to relieve musculoskeletal pain or spasmExamples: Flexeril™, Parafon Forte™
Paralytic medications
Clinically induce paralysis (like during surgery)Cut off communications between brain and musclesVery precise science; an overdose of these medications can stop heart or breathingExamples: succinylcholine (Anectine™), pancuronium (Pauvulon™)
interrelation between the nervous and muscular systems
motor neuron of nervous system initiates activity of muscle contraction through release of neurotransmitter called acetylcholine (ACh)