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35 Cards in this Set
- Front
- Back
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Sepsis |
Microbial contamination |
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Asepsis |
Absence of significant contaminnation |
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Antimicrobial chemical |
Destory pathogens but not sterilization |
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Disinfectant |
Antimicro chemical on object |
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Antispetic |
Antimicrobial chemical on living tissue |
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Nosocomial |
Disease from hospital |
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Sterilization |
Removal of microbes by heat,filter |
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Commercial sterilization |
For food |
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Sanitization |
Reduce # microbes to safe level |
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Bacteriostatic |
Inhibit bacterial reproduction |
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Bactericidal |
Kill bacteria |
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Rate of microbial death |
Constant rate |
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Biocide |
Kill harmful microbes |
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Antimicrobial treatment depends on.... |
#microbes, different susceptibilities,organic matter,time |
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Physical method of microbial control |
Heat (cheap,quick, best) |
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Thermal death point (TDP) |
Lowest T which kills culture in 10min |
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Thermal death time (TDT) |
Time to kill all cell in culture |
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Decimal reduction time (DRT) |
Minute to kill 90% of pop. at given T |
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Moist heat sterilization |
Autoclave |
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Pasteurization |
Significant # Reduction, no sterilize |
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Dry heat sterilization |
Flaming loop, incineration, hot air sterilization |
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Filtration |
Air filtration, membrane filter for fluid |
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Ionizing radiation |
Production of free radical and reactive molecule, Cold pasteurization, for heat sensitive ex) drug, food |
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UV light |
Cause tymine dimer lump in DNA |
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Microwave |
H2O absorb E and release heat and kill bacteria |
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Phenol |
Disrupt lipid plasma membrane, lipid rich cell wall |
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Chlorine |
Oxidizing agent , widely used ,form bleach , no sporicidal |
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Iodine |
Halogen, more effect then Cl, alter protein systhesis and membrane |
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Alcohol |
Denature protein,no effect on virus,fungi, spores |
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Heavy metal |
Protein denature (Hg,Cu,Ag,Zn) oligodynamic action |
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Oligodynamic action |
Toxic effec5 due to metal ion |
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Surfactant |
Soap, detergent, mechanical removal of microbes using wetting agent |
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Aldehydes |
Inactivate protein by cross-linking functional group |
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Chemical sterilant |
For heat sensive material, denature protein ex) ethylene oxide |
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H2O2 |
Oxdizing agent for anaerobic bacteria |
