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11 Cards in this Set
- Front
- Back
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Bethanechol
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Direct Agonist
Clinical Use: Post-operative neurogenic ileus and urinary retention Activates Bowel and Bladder smooth muscle; resistant to AChE. Bethany, call me if you want to activate your bowels and bladder!! |
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Carbachol
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Direct Agonist
Glaucoma, pupillary contraction, and relief of intraocular pressure Carbon copy of Acetylcholine |
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Pilocarpine
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Direct Agonist
Potent stimulator of seat, tears and saliva. Contracts the ciliary of the muscle (use for open angle glaucoma), pupillary sphincter (narrow angle glaucoma); resistant to AChE. Cry, drool, and sweat on you PILO. |
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Metacholamine
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Direct Agonist
Challenge test for Asthma diagnosis. Stimulates Muscarinic receptors in airway when inhaled causing bronchoconstriction. |
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Neostigmine
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Indirect agonist (anticholinesterase)
Postoperative and neurogenic ileus and urinary retention, myasenthia gravis, reversal of nueuromuscular blockade (post operative) Increases endogenous acetylcholine; No CNS penetration NEO CNS - No CNS penetration |
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Pyridostigmine
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Indirect agonist (anticholinesterase)
Myasenthia Gravis (long acting); doe not penetrate CNS Increases endogenous ACh, Increases strength |
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Edorphonium
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Indirect Agonist (Anticholinesterase)
Diagnosis of Myasenthia Gravis (Extremely short acting) Works by increasing endogenous ACH. |
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Physostigmine
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Indirect Agonist (anticholinesterase)
Used for Glaucoma (Crosses blood brain barrier --> CNS) also used to help with atropine overdose (Again, because it crosses the blood brain barrier) Phyxes atropine overdose |
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Echothiophate
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Indirect Agonist (anti- Acetylcholinesterase)
Glaucoma Increases endogenous ACh. |
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Donepezil
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Indirect agonist (Anticholinesterase)
Alzheimer's Disease Increases endogenous ACh. |
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Cholinesterase Inhibitor Poisoning
Organophosphates are components of insecticides. This type of poisoning is usually seen in Farmers. |
Often due to organophosphates, such as parathion, that irreversibly inhibit AChE.
Causes Diarrhea, Urination, Miosis, Bronchospasm, Bradycardia, Excitation of Skeletal muscle and CNS, Lacrimation, Sweating, Salivation DUMBBELSS |
