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9 Cards in this Set
- Front
- Back
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muscarinic agonists
choline esters |
acetylcholine
carbachol bethanechol |
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muscarinic agonists
natural alkaloids |
pilocarpine
muscarine |
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cholinesterase reversible inhibitors
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edrophonium
physostigmine neostigmine donepezil |
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cholinesterase irreversible inhibitors
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parathion (and other organophosphates)
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cholinesterase reactivators
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pralidoxime
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acetylcholine
carbachol bethanechol |
SE- local: visual difficulty on far vision or in dim light (carbachol, Ach)
-systemic: N/V, sweating, HTN, urgency CI- local: iritis, cataract, previous hx of retinal detachment -systemic: asthma, COPD, cardiac arhythmias, coronary artery disease, cyocardial disease, hypotension, PUD, IBD, hyperthyroidism Tx for- glaucoma, Myasthenia gravis (DX! edrophonium IV, TX! neostigmine, pyridostigmine, ambemonium PO), xerostomia, neurogenic bladder, Alzheimer's |
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pilocarpine
muscarine |
SE- mycetism
Tx for pilocarpine - open-angle glaucoma, xerostomia |
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edrophonium
physostigmine neostigmine donepezil organophosphates |
SE: fatigue, muscle cramps, fasciculations
Death usually due to respiratory failure Inhibits acetylcholinesterase and butyrylcholinesterase |
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pralidoxime
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Tx for poisoning by organophosphte insecticides
CI- GI and urinary tract obstruction, IBD, peritonitis, cholinergic crisis in the myasthenic pt, asthma, COPD, hypotension, cardiac arrhythmias, coronary artery disease, myocardial disease, PUD, hyperthyroidism, seizure disorder, Parkinson's |
