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5 Cards in this Set
- Front
- Back
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atropine |
MOA: non-selective muscarinic antagonist. large doses = penetrate CNS - preanesthetic to reduce salivary & respiratory secretions & induce amnesia - management of Parkinson's disease - mydriasis (dilation) of the eye - treat cholinergic poisoning from organophosphate cholinesterase inhibitors side effect: opposite of "SLUDS" - dry mouth, constipation, decreased sweating, mydriasis, urinary retention, tachycardia, decreased lacrimation, decreased respiratory secretions |
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scopolamine |
MOA: non-selective muscarinic antagonist. Exerts more CNS action than atropine (i.e. drowsiness & amnesia) - Antimotion sickness agent - management of Parkinson's disease - preanesthetic to reduce salivary & respiratory secretions & induce amnesia side effect: opposite of "SLUDS"- dry mouth, constipation, decreased sweating, mydriasis, urinary retention, tachycardia, decreased lacrimation, decreased respiratory secretions |
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ipratropium |
MOA: non-selective muscarinic antagonist
Treats Common Cold: Low dose to reduce secretions of nasopharynx |
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tubocurarine / atracurium |
MOA: nicotinic "motor end-plate" antagonist
Action lasts 20-40 mins tubocurarine = active ingredient in South American curare |
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succinylcholine |
MOA: nicotinic "motor end-plate" agonist = persistent depolarization of motor end-plate = prevent repolarization = relaxation of muscle short action 2-3 minutes -muscular relaxation in surgical anesthesia -muscular relaxation in orthopedic procedures -muscular relaxation for intubation |
