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10 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Mivacurium
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Non depolarizing competitive nAChR antagonist
Fast onset/duration Metabolised by plasma esterase Main side effect: transient hypotension |
Similar action to succinylcholine
Longer duration of action |
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Rocuronium
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Non-depolarizing nAChR antagonist
Fast onset/ 45 min duration of action Metabolized in liver, excreted by kidney Slight effect on heart rate |
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Vecuronium
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Non-depolarizing competitive nAChR antagonist
Intermediate onset and duration of action Liver and kidney deacylation |
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Pancuronium
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Intermediate onset
Long duration of action Non-depolarizing competitive nAChR antagonist Moderate block of Cardiac mAChR Kidney deacylation Widely used in surgery - long duration |
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Cisatracurium
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Slow onset
Intremediate duration Spontaneous hydrolysis in plasma Slight histamine release Widely used in surgery Bad for asthmatics Concern about hypotension and bronchoconstriction |
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Atracurium
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Slow onset / Intermediate duration
Spontaneous hydrolysis in plasma Low histamine release Degradation slowed by acidosys |
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Pipecuronium
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Short onset
Long duration Kidney deacetylation Not for kidney transplant |
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Metocurine
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Slow onset . Long duration
Blockade of nAChR antagonist |
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Tobocurarine
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Slow onset
long duration Insignificant metabolism Blockade of nAChR antagonist HIGH histamine release / no longer used clinically |
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Doxacurium
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Slow onset / long duration
None of anything Non-depolarizing competitive nAChR antagonist |
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