Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
10 Cards in this Set
- Front
- Back
|
treats post-op ileus, neurogenic ileus, urinary retention -resistant to AchE -direct agonist |
Bethanechol -activates smooth muscle of bowel and bladder |
|
|
treats open-angle glaucoma by reducing IOP and constricting pupil -direct agonist |
Carbachol |
|
|
Challenge test for diagnosis of asthma -direct agonist |
Methacholine -stimulates muscarinic receptors in airway |
|
|
Treats Sjogren Syndrome and any type of glaucoma (open and closed angle) -direct agonist -resistant to AChE |
Pilocarpine -contracts ciliary muscle of eye (OAG) -contracts pupillary sphincter (closed angle G) |
|
|
Treats Alzheimer disease by inhibiting AchE -indirect agonists |
Donezepil, galantamine, rivastigmine
|
|
|
Tensilon test for dg of myasthenia gravis -indirect agonist (blocks AChE) |
Edrophonium
|
|
|
Treats Post-operative ileus, neurogenic ileus, urinary retention, treats myasthenia gravis and REVERSES NMJ BLOCKADE -indirect agonist |
Neostigmine -does not enter CNS bc it is a quartenary amine |
|
|
Treats atropine overdose aka anticholinergic toxicity -indirect agonist -crosses CNS bc it is a tertiary amine |
Physostigmine
|
|
|
Long acting treatment for myasthenia gravis -does not enter CNS (4 amine) -indirect agonist |
Pyridostigmine
|
|
|
Farmer with new onset diarrhea, miosis, bronchospasm, bradycardia, excited skeletal muscles, tears, drool, sweat
|
Organophosphate poisoning--> irreversible inhibition of AchE-->way too much Ach-->cholinergic toxicity-need to treat with atropine (muscarinic antagonist)
|
