Chlamydia -Std's

Front 1

Describe the habitat of chlamydia species

Back 1

Chlamydia species are obligate intracellular parasites that target epithelial cells of the genital and respiratory tracts, as well as the conjunctiva

Front 2

What are the three important species of chlamydia according to the old taxonomy?

Back 2

C. trachomatis, C. pneumonia, and C. psittaci

Front 3

Which serovars of C. trachomatis cause trachoma?

Back 3

A, B, Ba, and C

Front 4

Which serovars of C. trachomatis cause STDs and conjunctivitis?

Back 4

serovars D-K

Front 5

What serovars of C. trachomatis cause lymphogranuloma venereum?

Back 5

L1-L3

Front 6

What is the natural host of C. psittaci?

Back 6

Birds, as well as humans

Front 7

What are the target host cells for chlamydia?

Back 7

columnar epithelial cells lining mucous membranes of humans and animals such as the urethra, endocervix, endometrium, fallopian tubes, rectum, respiratory tract, and conjunctiva

Front 8

Describe the cellular location of chlamydia

Back 8

They are located within phagosomes of the host cells, which become known as "inclusions"

Front 9

What are the two different types of chlamydia bacteria?

Back 9

Elementary bodies and reticulate bodies

Front 10

Describe elementary bodies

Back 10

They are infectious chlamydia responsible for entry and attachment to the epithelium and contain a rigid cell wall allowing for it to survive environmental stress

Front 11

Describe reticulate bodies

Back 11

They are metabolically active forms of chlamydia found within the phagosome that form the inclusions; they are gram negative with no peptidoglycan

Front 12

Describe the transmission of chlamydia

Back 12

It is transmitted by mucosal secretions from an infected person or animal

Front 13

What are the most important cellular antigens of chlamydia?

Back 13

LPS, type specific serovars, and MOMP (A heat-labile protein on the surface of the elementary body)

Front 14

From where should a specimen be collected for diagnosis of C. trachomatis L1-L3?

Back 14

Aspirate from an infected lymph node

Front 15

From where should a specimen be collected for the diagnosis of C. trachomatis D-K?

Back 15

Swabs of the cervix in men and urethra in men

Front 16

What is the best way to diagnose a chlamydia infection?

Back 16

Microscopic examination with antibody labeling for specific antigens

Front 17

What is a trachoma?

Back 17

The leading preventable cause of blindness in the world; due to C. trachomatis serovars A-C

Front 18

Describe the clinical manifestations of trachoma

Back 18

It begins in childhood as an inflammation of the conjunctival epithelium that progresses to a purulent conjunctivitis which eventually develops blindness due to scarring of the conjunctiva and deformity of the eyelids

Front 19

Describe the transmission of C. trachomatis serovars D-K

Back 19

It is transmitted person-to-person via sexual contact (most common sexually transmitted pathogen)

Front 20

What are the clinical manifestations of C. trachomatis serovars D-K?

Back 20

1) Nongonococcal urethritis (males) 2) Cervicitis (females) 3) Acute pelvic inflammatory disease 4) Reiter's syndrome

Front 21

Describe nongonococcal urethritis

Back 21

This is an STD caused by C. trachomatis D-K that occurs in males and is an infection of the urethra with a clear to purulent discharge occurring with or without pain; gram stain shows neutrophils and no organisms

Front 22

Describe Cervicitis

Back 22

This is the C. trachomatis D-K infection that occurs in females with inflammation of the cervix with mucoid or purulent discharge and can be asymptomatic (75%)

Front 23

Describe pelvic inflammatory disease caused by C. trachomatis D-K

Back 23

It may spread to the fallopian tubes producing scarring leading to infertility and ectopic pregnancy; subacute or chronic mild abdominal pain

Front 24

What is Reiter's syndrome?

Back 24

A reactive arthritis, urethritis, and uveitis following C. trachomatis D-K infection and associated with HLA-B27

Front 25

Describe how one would treat C. trachomatis D-K infection

Back 25

You would co-treat for gonorrhea

Front 26

What is inclusion conjunctivitis?

Back 26

Purulent conjunctivitis that heals without scarring in neonates who become infected during passage through an infected birth canal; incubation period 5-21 days

Front 27

What is also seen in addition to inclusion conjunctivitis in neonates infected with C. trachomatis D-K?

Back 27

Pneumonia with cough and little fever

Front 28

What are the clinical manifestations of lymphogranuloma venereum?

Back 28

Small painless ulcers at the site of sexual contact which heal, but then progress to inguinal lymphadenopathy with painful nodes 2-6 weeks later

Front 29

Describe the transmission of C. pneumonia

Back 29

It is transmitted person to person via respiratory secretions, mostly seen in school-aged children and young adults

Front 30

What kind of pneumonia is C. pneumonia?

Back 30

Community acquired atypical pneumonia'

Front 31

What are the clinical manifestations of C. pneumonia infection?

Back 31

Pharyngitis that progresses to bronchitis with a mild to severe atypical pneumonia

Front 32

From what organism must C. pneumonia be distinguished?

Back 32

Mycoplasma pneumonia

Front 33

How is C. psittaci transmitted?

Back 33

Inhalation of the organism from infected birds and their droppings

Front 34

Describe the clinical manifestations of a C. psittaci infection

Back 34

The infection is often mild and asymptomatic and caused an atypical pneumonia that can disseminate to the liver, spleen, heart, ect. in immunocompromised patients