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30 Cards in this Set
- Front
- Back
what is special about chlamydia that affects treatment
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no peptidoglycan layer so can't be treated with penicillin
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why is chlamydia an obligate intracellular organism
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needs ATP
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what are the two forms of chlamydia
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elementary body and reticular body
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C pneumonia is refered to as the?
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TWAR STRAIN
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what percent of the US seroconverts with Chlamydia pneumonia
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30-50 is infected and can seroconvert when their immune system is comp
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what is c pneumonia associated with
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atheroscleritic plaque
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C. psittaci is associated with?
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influenza or pneumonia from pet birds
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C. trachomatis is associated with is associated with?
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eye and genital infection
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what are the serotypes associated with disease (serotypes are based on outer membrane differences)
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A-L
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what is trachoma infection serotype
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A, B, C
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Trachoma infection is common where?
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middle east, pacific Islands, Asia
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how does trachoma work
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lymphoid follicles form turning the eyelids inward and scarring the cornea with the eyelashes
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Inclusive conjunctivitis involves what serotypes
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D-K
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what is inclusive conjunctivitis
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mucopurulent discharge 2-25 days following birth resolves slowly over a few months
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what is inclusive conjuntivits associated with
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neonate pneumonia, afebrile, low mortality
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non-gonococcal urethritis is associated with what serovars
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D-K
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what is the most common non-gonococcal urithritis
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chlamydia 30-50%
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how much more common is chlamydia than gonnorhea
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2-3 x
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what percent of males are asymptomatic
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10%
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what percent of people are coinfected with chlam and gon
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30%
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how long does gonorrhea take to show up? how long does chlamydia
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gon takes 2-7 days chlam takes 2-3 weeks
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does gonorrhea or chlamydia have bacteria in the exudate
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neither
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chlamydia can cause ? in women
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cervicitis which may progress to PID in 8% and can be associated with third trimester abortions
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LGV (lymphogranuloma venereum) serovars?
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L1, L2, L3 only 300/year in US mostly in africa, asia, south america
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how does LGV present
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inguinal Buboes
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Chlamydia is associated with what syndrome/sequela
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Reiters (arthritis, conjunctiva, urethritis)
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how do you diagnose chlamydia
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ELISA, IF confirm with culture and PCR
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epidemiology of chlamydia
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6 million cases of blindness, 10-40% of african children are infected
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what is the response to chlamydia
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humoral
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treatment
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doxycycline or azithromycin NOT SILVER NITRATE
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