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15 Cards in this Set
- Front
- Back
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Describe Gefitinib
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Inhibits tyrosine kinase epidermal growth factor receptor.
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Describe IL-2
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Self vs. nonself, infection. BRM.
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Describe proleukin
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Used for malignant melanoma. BRM. In trials for a vaccine booster
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Name monoclonal antibodies to CA cells
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*mab.
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Describe bone marrow supression in chemotherapy
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Starts 7-10 days, maximal 10-14. Recovery = 2-3 wks.
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How is neutropenia tx'd in CA pts.
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filgratim (Neupogen)
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How is anemia tx'd in CA pts.
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darbepoetin alpha (Aranesp) of Epo (epogen or procrit)
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Which chemo drugs cause significant bone-marrow depression?
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Daunorubicin, doxorubicin, paclitaxel, carmustine, cytarabine
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Which chemo agents cause little/no bone marrow depression
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Vincristine, asparaginase, bleomycin.
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What chemo drugs commonly cause alopecia
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cyclophosphamide, doxorubicin, mechlorethamine, paclitaxel
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What chemo drugs commonly cause skin [incl. GI] changes?
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methotrexate, fluorouracil
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What chemo drug cause pulmonary fibrosis
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Busulfan, carmustine, chlorambucil, mitomycin
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What chemo drug causes bronchospasm
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vincristine
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Which chemo drugs cause dose-related cardiac toxicity?
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Xocorubicin, baunorubicin, high-dose cytoxin and busulfan
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What chemo drug causes hypotension/hypertension, tachycardia and AV block?
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Taxol
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