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12 Cards in this Set
- Front
- Back
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What agents are cell-cycle nonspecific?
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Nitrosoureas
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What chemo meds are given intrathecally?
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methotrexate, hydrocortisone, cytarabine, and thiotepa
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What is dosing of chemo meds based on?
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BSA
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What is cell kill theory?
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Drug should kill 90% of cells in first round of tx, and 90% second round.
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What are the anesthetic implications of vincristine?
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muscle wasting -> elevated K+, peripheral neuropathy
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What are the anesthetic implications of adriamycin
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cardiomyopathy
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What are the anesthetic implications of procarbazine?
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MAOI activity
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What are the anesthetic implications of 6-mercaptopurine
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potentiates NDNMBs
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What are the anesthetic implications of cytoxan
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inhibits pseudocholinesterase
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What are the anesthetic implications of bleomycin
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Keep FiO2 < 28% to decrease superoxide/free radical damage. Blood loss replaced w/ colloids to prevent pulmonary edema.
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What are the anesthetic implications of cisplatin?
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renal insufficiency
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What labs do we want w/ chemo pts?
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CBC, ABG, lytes, liver fx, creatinine, EKG, CXR
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