Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
41 Cards in this Set
- Front
- Back
|
Malathion is metabolized into what by insects by converting a P=S bond into a P=O bond?
|
Malaoxon
|
|
|
Malaoxon inhibits what enzyme by reacting with what amino acid?
|
Acetylcholine esterase (AChe)
reacts with Serine amino acid |
|
|
Malathion hydrolyzes an ester linkage in humans making what?
|
Malathion Acid
|
|
|
Sarin is an example of a what?
|
Nerve gas
|
|
|
botulinum toxin is used for what, and made from what bacteria? What does it do?
|
Botox, and is from clostridium botulinum
Impairs neurons ability to release aCh |
|
|
Tetanus toxin is made from what bacteria, and what do it do?
|
Clostridium tetani, it inhibits the use of inhibitory excitation neurons, so that your muscles contract and don't know when to stop.
|
|
|
What is primarily in Tetanus vaccines?
|
Formaldehyde
|
|
|
What does arsenic do biologically?
|
it competes with phosphate groups in binding to adenosine therefore inhibiting the creation of ATP.
|
|
|
What have low levels of Arsenic poisoning been correlated with?
|
skin sores
|
|
|
what have high levels of arsenic poisoning been correlated with?
|
Abortions, and lung, bladder and other cancers
|
|
|
1080 is also know as
|
fluoroacetate
|
|
|
fluoroacetate is converted into fluoroacetyl CoA, and then competes with acetyl CoA to inhibit an enzyme which then does what?
|
shuts down the kreb's cycle
|
|
|
what's a non-competitive inhibitor?
|
an inhibitor which binds to a site other than the active site, which still inhibits the enzyme because the shape has changed making it not recognizable
|
|
|
Lead poisoning can cause....
|
damage to red blood cells, and nerve cells
|
|
|
What is the most common source of lead poisoning in the environment?
|
Children eating peeling paint (Lead based paints)
|
|
|
In the 1800's Mercury used to be used to make what fabric?
|
wool
|
|
|
What is the name of the vaccine in which mercury is found?
|
Thimerosal or Merthiolate
|
|
|
What major disorders were claimed to be caused from Thimerosal?
|
ADHD, and Autism
|
|
|
Silver nitrate was used formerly as a what for newborns?
|
anti-microbial agent that was dropped into baby's eyes
|
|
|
What is neutral silver and silver salts used for?
|
anti-bacteria, and promotes wound healing
|
|
|
The term for another binding site besides the substrate site on an enzyme
|
allosteric site
|
|
|
what's a proenzyme
|
and enzyme with an extra peptide so that it isn't active
|
|
|
what is the in-active form of trypsin?
|
trypsinogen
|
|
|
what is the in-active form of chymotrypsin
|
chymotrypsinogen
|
|
|
enzyme which add phosphates to enzymes
|
kinase enzymes
|
|
|
what is the futile cycle?
|
doing two things at once, which is burning unnecessary energy
|
|
|
what do chaperone or chaperonin proteins do?
|
help big proteins fold
|
|
|
what does ubiquitin do?
|
it marks the protein for hydrolysis by protein complexes called proteasomes
|
|
|
the beta pleated sheet formation of protein folding has a higher risk of...
|
polymerizing in insoluble fibrils or plaque
|
|
|
what does prion (PrP) stand for?
|
Proteinaceous Infectious Protein
|
|
|
what does PrP Sc stand for?
|
Scrapie, a disease found in sheeps
|
|
|
True or False: PrP Sc can act as a catalyst to change normal PrP proteins into misfolded proteins
|
true
|
|
|
what amyloid protein is found in alzheimer's patients?
|
Beta amyloid
|
|
|
people with what lipo protein are at higher risk for alzheimers?
|
apolipoprotein E (apo e)
|
|
|
aggregated alpha synuclein plaque which promotes alternate folding is called what?
|
Lewy Bodies, which are found in people with Parkinson's disease.
|
|
|
chronic arsenic poisoning is severe in Bangladesh
|
.
|
|
|
purine is...
|
6 membered ring attached to 5 membered ring
|
|
|
prime numbers mean
|
ribose
|
|
|
phosphates between 1-3 phosphate make
|
nucleotides
|
|
|
Damp, the D=?
|
D stands for Deoxy
|
|
|
dna polymerization of is catalyzed by?
|
dna polymerase
|
