Chemistry

Front 1

which of the following hormones is often decrease by approx 25% in the serum of pregnant woman who have fetus with Down's syndrome

Back 1

estriol (E3)

Front 2

the syndrome of inappropriate antidiuretic hormone secretion (SIADH) causes

Back 2

low serum electrolytes

Front 3

select the hormones that is ass w/ galactorhea, pituitary adenoma & amenorrhea

Back 3

prolactin

Front 4

Zollinger Ellison (ZE) syndrome is characterized by great (eg 20 fold) elevation of

Back 4

Gastrin

Front 5

which statement about mx endocrine neoplasia (MEN) is true

Back 5

it is ass w/ hyperplasia or neoplasia of at least 2 endocrine organs

Front 6

select the main estrogen produced by the ovaries and use to eva ovarian functions

Back 6

estradiol (E2)

Front 7

which statement best describes the relationship betwn luteinizing hormone (LH) and FSH in cases of dymenorrhea

Back 7

both hormones normally peaks 1 - 2 days before ovulation

Front 8

when pituitary adenoma is the cause of decrease estrogen production, an increase of which hormones is most frequently responsible

Back 8

prolactin

Front 9

which of the following statement is correct in assessing GH defncy

Back 9

pituitary failure may involve one, several, or all adenohyprophyseal hormones, but GH defncy is usually found

Front 10

which statement best describe the level of GH in patient with pituitary adenoma ass w/ acromegaly

Back 10

some pat req a glucose suppression test to test a diagnosis

Front 11

hyperparathyroidism is most consistently ass w/

Back 11

hypophosphatemia

Front 12

PTH levels diff primary and secondary cause by

Back 12

hypocalcemia

Front 13

the best method of analysis for serum PTH inv using antibodies that detect

Back 13

both the amino terminal fragment & intact PTH

Front 14

which of the following is most often elevated in hypercalcemia ass w/ malignancy

Back 14

PTHRP - parathyroid hormone related proteins

Front 15

steriods w/ a dihydroxyacetone group at C17 are classified as

Back 15

17 hydroxycorticosteroids

Front 16

which statement below regarding adrenal cortical dysfunction is true

Back 16

Cushing's syndrome is ass w/ glucose intolerance

Front 17

which of the following statement about cortisol in Cushing's syndrome is true

Back 17

24 hour urinary free cortisol is a more sensitive test than plasma total cortisol

Front 18

which of the following disease is characterized by primary hyperadpsteronism caused by adrenal adenoma, carcinoma or hyperplasia

Back 18

Conns disease

Front 19

which of the following is the most common cause of Cushing's syndrome

Back 19

overuse of corticosteroids

Front 20

which of the following is the mechx causing Cushing's disease

Back 20

excess secretion of pituitary ACTH

Front 21

in which situation is the plasma or 24 hour urinary cortisol not consistent w/ the clinical picture

Back 21

eva of congenital adrenal hyperplasia

Front 22

which test is used to distinguish Cushing's disease (pituitary Cushings) from Cushing's syndrome caused by adrenal tumors

Back 22

serum ACTH

Front 23

which is the most widely used screening test for Cushing's syndrome

Back 23

overnight deamethasone suppression test

Front 24

which test is the most specific for est a diagnosis of Cushing's disease (pituitary Cushing's)

Back 24

petrosal sinus sampling following corticotropin releasing hormone stimulation

Front 25

primary & secondary Addisons dz can often be diff by

Back 25

plasma ACTH

Front 26

which of the statement below regarding the catecholamines is true

Back 26

plasma levels show both diurnal & pulsed variation

Front 27

which assay using 24 hour urine is considered the best single screen testing for pheochromocytoma

Back 27

metanephrines

Front 28

which metabolite is most often increased in carcinoid tumors of the intestines

Back 28

5- hydroxyindolacetic aid (5-HIAA)

Front 29

which statement regarding the mz of urinary catecholamines is true

Back 29

24 hours urinary catecholamine assay avoids pulse variation ass w/ mzment of plasma catecholamines

Front 30

which method used to mz catecholamines is the LEASE specific

Back 30

mzment of fluorescence following oxidation by potassium ferricyanide

Front 31

which statement about sample collection for catecholamines & metabolites is true

Back 31

24 hours urine creatinine should be mz w/ vanillylmadelic acid, homovanillic acid or metanephrines

Front 32

which statement below applies both mzment of VMA and meanephrines in urine

Back 32

both can be mz by specific HPLC and GCMS assays

Front 33

urinary HVA is most often assayed to detect

Back 33

neuroblastoma

Front 34

thyroid hormones are derived from an amino acid

Back 34

tyrosin

Front 35

T3 is about ___ ___ ___ than T4

Back 35

tenfold more active

Front 36

total T3 and T4 are influenced b the level of ___ ___ ___

Back 36

thryoxine binding globulin

Front 37

which of the following condtx increases total T4 by increasing thyroxine binding globulin (TBG)

Back 37

pregnancy or estrogen

Front 38

select the most appropriate single screening test for thyroid disease

Back 38

Total T4

Front 39

the serum TSH level is decreased in

Back 39

primary hyperthyroidism

Front 40

which assay i most specific & sensitive test for diagnosing thyroid disease

Back 40

thyrotropin releasing hormone (TRH_ stimulation test

Front 41

which of the following statement is true regarding revere T3 (rT3)

Back 41

formed in the blood by degradation of T4

Front 42

a pat has:
elevated serum T3 and free T4
very low serum TSH
what is the likely cause

Back 42

primary hyperthyroidism

Front 43

a serum thyroid panel reveals
increase in Total T4
normal TSH
normal Free T4
what is the likely cause

Back 43

euthyroid w/ increased thyroxine binding protein

Front 44

which statement about TSH & T4 in early pregnancy is correct

Back 44

TSH fails and thyroid hormones levels rise

Front 45

in which case might a very low plasma TSH results not correlated w/ thyroid status

Back 45

after high dose corticosteroid treatment