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85 Cards in this Set
- Front
- Back
Cell |
The structural and functional unit of life |
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3 basic parts of a cell |
Plasma membrane, cytoplasm, and nucleus |
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Examples of extracellular fluids |
Interstitial fluid, blood plasma, and cerebrospinal fluid |
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The plasma membrane has composed of... |
Membrane lipids, membrane proteins, glycocalyx, and cell junctions |
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The lipid bilayer is made up of... |
75% phospholipids, 5% glycolipids, and 20% cholesterol |
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Phosphate heads are... |
Hydrophilic (water-loving) |
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Phospholipid tails are... |
Hydrophobic (water-hating) and nonpolar |
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Glycocalyx consists of... |
Sugars sticking out of cell's surface |
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3 types of cell junctions |
Tight junctions, desmosomes, and gap junctions |
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Tight junctions are... |
Found on integral proteins and form an impenetrable junction that encircles the whole cell |
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Desmosomes are... |
A rivet-like cell junction further when linker proteins interlock proteins of neighboring cell like a zipper; allow give between cells reducing the possibility of tearing under tension |
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Gap junctions are... |
Transmembrane protein connexons which form tunnels to allow small molecules to pass from cell to cell |
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Two ways substances move across cell membrane |
Passive processes (no energy required) and active processes (ATP required) |
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Two types of passive transport |
Diffusion and filtration |
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3 types of diffusion |
Simple, facilitated, and osmosis |
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2 types of facilitated diffusion |
Carrier-mediated and channel-mediated |
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Simple diffusion allows________to pass through phospholipid barrier |
Nonpolar lipid-soluble substances (oxygen, carbon dioxide, fat soluble vitamins) |
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Facilitated diffusion allows________to be transported |
Certain hydrophobic molecules (glucose, amino acids, and ions) |
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Carriers are |
Transmembrane integral proteins |
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Carriers are__________when all are bound to molecules and are busy transporting |
Saturated |
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Two types of channels |
Leakage channels (always open) and gated channels (controlled by chemical or electrical signals) |
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Osmosis |
Movement is solvent such as water across a selectively permeable membrane either through lipid bilayer or through specific water channels called aquaporins. |
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Osmolarity |
Measure of total concentration of solute particles |
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Hydrostatic pressure |
Pressure of water inside cell pushing on membrane |
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Osmotic pressure |
Pressure of water outside cell pushing to move into cell by osmosis |
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Isotonic solution |
Has same osmolarity as inside cell so volume remains unchanged |
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Hypertonic solution |
Had higher osmolarity than inside cell so water flows out of cell resulting in shrinking |
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Shrinking of cell is referred to as |
Crenation |
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Hypotonic solution |
Had lower osmolarity than inside cell so water flows into cell resulting in swelling |
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Nursing of cell referred to as |
Lysing |
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Two major types of active membrane transport |
Active transport and vesicular transport |
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Active transport requires_________ and _________ |
ATP and carrier proteins |
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2 types of carriers which transport more than one substance |
Antiporters (transports one substance in and one out) and Symporters (transports two different substances in same direction) |
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Two types of active transport |
Primary and secondary |
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Required energy comes directly from ATP hydrolysis |
Primary active transport |
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Required energy is obtained indirectly from ionic gradients |
Secondary active transport |
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3 types of vesicular transport |
Endocytosis, exocytosis, and transcytosis |
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3 types of endocytosis |
Phagocytosis, pinocytosis, and receptor-mediated endocytosis |
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Phagocytosis |
Type of endocytosis referred to as cell-eating |
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Pinocytosis |
Type of endocytosis referred to as cell-drinking |
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Phagocytosis vesicle |
Phagosome |
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Phagocytic cells move by |
An amoeboid motion |
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Cell receptors are embedded in |
Clathrin-coated pits |
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Exocytosis |
Process where material is ejected from cell |
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Substance ejected from cell is enclosed in a |
Secretory vesicle |
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Resting membrane potential is |
Electrical potential energy produced by separation of oppositely charged particles across plasma membrane in all cells |
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Difference in electrical charge is called |
Voltage |
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Cells that have charge are said to be |
Polarized |
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Most cells have an RMP of around |
-90mV |
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Cells interact with their environments by |
Responding directly to other cells or indirectly to extracellular chemicals |
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Cell interactions always involve |
Glycocalyx |
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Cells use these to communicate |
Cell adhesion molecules (CAMs) and plasma membrane receptors |
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Functions of CAMs include |
Anchoring cell, assisting in movement of cell's past one another, attracting WBCs to injured or infected areas, stimulating synthesis or degradation of adhesive membrane junctions, and transmitting intracellular signals |
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Types of chemical signaling |
Contact signaling and chemical signaling |
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Contact signaling |
Cells that touch recognize each other by each cells unique surface membrane receptors |
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Chemical signaling |
Interaction between cells and ligands that cause changes in cellular activity |
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Ligands |
Chemical messengers |
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G-protein linked receptors |
Indirectly cause cellular changes by activating G proteins which in turn can affect ion channels, activate other enzymes, out cause release of internal second messenger chemicals |
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Membraneous cell organelles include |
Mitochondria, endoplasmic reticulum, Golgi apparatus, peroxisomes, and lysosomes |
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Non membranous cytoplasmic organelles include |
Ribosomes, cytoskeleton, and centrioles |
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Function of mitochondria |
Produce most of the cells energy (ATP) molecules; inner membrane folds called cristae |
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2 types of ribosomes |
Free ribosomes and membrane-bound ribosomes attached to rough ER |
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Rough ER function |
Site of protein synthesis, plasma membrane proteins, and phospholipids |
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Smooth ER function |
Lipid metabolism; absorption, synthesis, and transport of fats |
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Golgi apparatus function |
Modifies, concentrates, and packages proteins and lipids; "traffic director" |
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Peroxisomes |
Neutralize toxins such as free radicals using oxidase and catalase; breakdown and synthesis of fatty acids |
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Lysosome function |
Cell digestion; autolysis |
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Tay-Sachs disease |
A condition in which the patient lacks a lysosomal enzyme needed to break down glycolipids in brain cells |
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3 types of rods make up cytoskeleton |
Microfilaments (thinnest), intermediate filaments, and microtubules (thickest) |
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Microfilaments composed of semi flexible strands of |
Actin (protein) |
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Intermediate filaments composed of |
Tough, insoluble, ropelike protein fibers called tetramer fibrils |
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Microtubules composed of |
Protein subunits called tubulins |
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Microtubules radiate from |
Centrosome area of cell |
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Motor proteins |
Move substances throughout cell along microtubules powered by ATP |
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Centrosome function |
Means "cell center"; is a microtubules organizing center consisting of a granular matrix of centrioles |
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Cilla and flagella |
Aid in the movement of the cell or of materials across cell surface |
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Microvilli |
Finger-like projections that extend from cell surface to increase cell surface area |
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Most cells are_______ |
Uninucleate |
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Cells that are multinucleate include |
Skeletal muscle, certain bone cells, and some liver cells |
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A type of anucleate cell |
Red blood cells |
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3 main structures of nucleus |
Nuclear envelope, nucleoli, and chromatin |
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Chromatin consists of |
30% DNA strands, 60% histone proteins, and 10% RNA |
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Chromosomes |
Condensed chromatin |
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2 major periods of cell cycle |
Interphase and cell division (mitotic phase) |
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Interphase consists of these subphases |
G1 (growth and metabolism), or G0 if cell had permanently ceased dividing, S (synthetic/DNA replication), and G2 (preparation for division) |