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85 Cards in this Set

  • Front
  • Back

Cell

The structural and functional unit of life

3 basic parts of a cell

Plasma membrane, cytoplasm, and nucleus

Examples of extracellular fluids

Interstitial fluid, blood plasma, and cerebrospinal fluid

The plasma membrane has composed of...

Membrane lipids, membrane proteins, glycocalyx, and cell junctions

The lipid bilayer is made up of...

75% phospholipids, 5% glycolipids, and 20% cholesterol

Phosphate heads are...

Hydrophilic (water-loving)

Phospholipid tails are...

Hydrophobic (water-hating) and nonpolar

Glycocalyx consists of...

Sugars sticking out of cell's surface

3 types of cell junctions

Tight junctions, desmosomes, and gap junctions

Tight junctions are...

Found on integral proteins and form an impenetrable junction that encircles the whole cell

Desmosomes are...

A rivet-like cell junction further when linker proteins interlock proteins of neighboring cell like a zipper; allow give between cells reducing the possibility of tearing under tension

Gap junctions are...

Transmembrane protein connexons which form tunnels to allow small molecules to pass from cell to cell

Two ways substances move across cell membrane

Passive processes (no energy required) and active processes (ATP required)

Two types of passive transport

Diffusion and filtration

3 types of diffusion

Simple, facilitated, and osmosis

2 types of facilitated diffusion

Carrier-mediated and channel-mediated

Simple diffusion allows________to pass through phospholipid barrier

Nonpolar lipid-soluble substances (oxygen, carbon dioxide, fat soluble vitamins)

Facilitated diffusion allows________to be transported

Certain hydrophobic molecules (glucose, amino acids, and ions)

Carriers are

Transmembrane integral proteins

Carriers are__________when all are bound to molecules and are busy transporting

Saturated

Two types of channels

Leakage channels (always open) and gated channels (controlled by chemical or electrical signals)

Osmosis

Movement is solvent such as water across a selectively permeable membrane either through lipid bilayer or through specific water channels called aquaporins.

Osmolarity

Measure of total concentration of solute particles

Hydrostatic pressure

Pressure of water inside cell pushing on membrane

Osmotic pressure

Pressure of water outside cell pushing to move into cell by osmosis

Isotonic solution

Has same osmolarity as inside cell so volume remains unchanged

Hypertonic solution

Had higher osmolarity than inside cell so water flows out of cell resulting in shrinking

Shrinking of cell is referred to as

Crenation

Hypotonic solution

Had lower osmolarity than inside cell so water flows into cell resulting in swelling

Nursing of cell referred to as

Lysing

Two major types of active membrane transport

Active transport and vesicular transport

Active transport requires_________ and _________

ATP and carrier proteins

2 types of carriers which transport more than one substance

Antiporters (transports one substance in and one out) and Symporters (transports two different substances in same direction)

Two types of active transport

Primary and secondary

Required energy comes directly from ATP hydrolysis

Primary active transport

Required energy is obtained indirectly from ionic gradients

Secondary active transport

3 types of vesicular transport

Endocytosis, exocytosis, and transcytosis

3 types of endocytosis

Phagocytosis, pinocytosis, and receptor-mediated endocytosis

Phagocytosis

Type of endocytosis referred to as cell-eating

Pinocytosis

Type of endocytosis referred to as cell-drinking

Phagocytosis vesicle

Phagosome

Phagocytic cells move by

An amoeboid motion

Cell receptors are embedded in

Clathrin-coated pits

Exocytosis

Process where material is ejected from cell

Substance ejected from cell is enclosed in a

Secretory vesicle

Resting membrane potential is

Electrical potential energy produced by separation of oppositely charged particles across plasma membrane in all cells

Difference in electrical charge is called

Voltage

Cells that have charge are said to be

Polarized

Most cells have an RMP of around

-90mV

Cells interact with their environments by

Responding directly to other cells or indirectly to extracellular chemicals

Cell interactions always involve

Glycocalyx

Cells use these to communicate

Cell adhesion molecules (CAMs) and plasma membrane receptors

Functions of CAMs include

Anchoring cell, assisting in movement of cell's past one another, attracting WBCs to injured or infected areas, stimulating synthesis or degradation of adhesive membrane junctions, and transmitting intracellular signals

Types of chemical signaling

Contact signaling and chemical signaling

Contact signaling

Cells that touch recognize each other by each cells unique surface membrane receptors

Chemical signaling

Interaction between cells and ligands that cause changes in cellular activity

Ligands

Chemical messengers

G-protein linked receptors

Indirectly cause cellular changes by activating G proteins which in turn can affect ion channels, activate other enzymes, out cause release of internal second messenger chemicals

Membraneous cell organelles include

Mitochondria, endoplasmic reticulum, Golgi apparatus, peroxisomes, and lysosomes

Non membranous cytoplasmic organelles include

Ribosomes, cytoskeleton, and centrioles

Function of mitochondria

Produce most of the cells energy (ATP) molecules; inner membrane folds called cristae

2 types of ribosomes

Free ribosomes and membrane-bound ribosomes attached to rough ER

Rough ER function

Site of protein synthesis, plasma membrane proteins, and phospholipids

Smooth ER function

Lipid metabolism; absorption, synthesis, and transport of fats

Golgi apparatus function

Modifies, concentrates, and packages proteins and lipids; "traffic director"

Peroxisomes

Neutralize toxins such as free radicals using oxidase and catalase; breakdown and synthesis of fatty acids

Lysosome function

Cell digestion; autolysis

Tay-Sachs disease

A condition in which the patient lacks a lysosomal enzyme needed to break down glycolipids in brain cells

3 types of rods make up cytoskeleton

Microfilaments (thinnest), intermediate filaments, and microtubules (thickest)

Microfilaments composed of semi flexible strands of

Actin (protein)

Intermediate filaments composed of

Tough, insoluble, ropelike protein fibers called tetramer fibrils

Microtubules composed of

Protein subunits called tubulins

Microtubules radiate from

Centrosome area of cell

Motor proteins

Move substances throughout cell along microtubules powered by ATP

Centrosome function

Means "cell center"; is a microtubules organizing center consisting of a granular matrix of centrioles

Cilla and flagella

Aid in the movement of the cell or of materials across cell surface

Microvilli

Finger-like projections that extend from cell surface to increase cell surface area

Most cells are_______

Uninucleate

Cells that are multinucleate include

Skeletal muscle, certain bone cells, and some liver cells

A type of anucleate cell

Red blood cells

3 main structures of nucleus

Nuclear envelope, nucleoli, and chromatin

Chromatin consists of

30% DNA strands, 60% histone proteins, and 10% RNA

Chromosomes

Condensed chromatin

2 major periods of cell cycle

Interphase and cell division (mitotic phase)

Interphase consists of these subphases

G1 (growth and metabolism), or G0 if cell had permanently ceased dividing, S (synthetic/DNA replication), and G2 (preparation for division)