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18 Cards in this Set
- Front
- Back
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NaNO2, HCl, H2O |
+N=O |
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1. KMnO4, NaOH, heat 2. H+, H2O |
Turns any benzylic carbons into carboxylic acids |
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R-CN to R-C=O |
1. DIBAL-H 2. H+, H2O |
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eliminating an amine |
1. CH3I 2. Ag2O 3. heat |
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make a phenol |
chlorobenzene, H2O, Na2CO3, 100 C |
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NH2 on benzene to Cl on benzene |
1. HCl, NaNO2, 0 C 2. CuCl, 60 C |
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carbonyl to amine |
NaBH3CN, EtOH, plus half-desired amine |
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beta keto amine |
Carbonyl, formaldehyde, amine, HCl, ethanol, heat |
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put on thiol protecting group |
ZnCl2 |
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take off thiol protecting group |
HgCl2, CaCO3, CH3CN, H2O |
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NaNH2, -78 C plus benzene with good leaving group |
takes an alpha hydrogen, pushes off leaving group, makes benzyne |
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Amide, Br2, NaOH, H2O |
Hofmann rearrangement to get CO2 and primary amine |
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Amine plus carbonyl with NaBH3CN, EtOH |
nitrogen replaces oxygen, but with single bond instead of double bond |
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Halogen to amine |
1. NaN3 2. (1. LiAlH4 2. HCl, H2O) |
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NH2 on benzene to Br |
1. HBr, NaNO2, 0 C 2. CuBr, 100 C |
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alpha keto alcohol |
2 aldehydes plus thiazonium salt, NaOH, H2O |
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NO2 on benzene to NH2 |
Fe, HCl |
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1. DIBAL-H 2. H2O |
Reduces carboxylic acid derivatives to aldehydes |
