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31 Cards in this Set

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Oxidative phosphorylation


1. where in the cell specifically does it occur?


2. what are the inputs?


3. what are the outputs?

1. inner mitochondrial membrane


2. oxygen, 2FADH,NADH2


3. H2O, ATP

How can ATP synthesis be uncoupled?

Different H+ diffusion channel is inserted into the mitochondrial membrane

What is the consequence of uncoupling?

Not much ATP is produced, energy lost as heat

In what or whom does uncoupling occur

Uncoupling protein thermogenin occurs in infants and hibernating animals

The absence of oxygen (anaerobic)how is ATP produced?

In glycolysis

Lactic acid fermentation:


1. Where does this occur in the cell in with which steps of respiration?


2. Which type of cells does this occur


3. What is the input?


4. What is the products?

1. Cytosol; glycolysis


2. Micro organisms and muscle cells.


3. Glucose.


4. 2 ATP, lactic acids

Alcohol fermentation


1. Where does this occur in the cell and with which steps of respiration?


2. Which type of cell does this occur


3. What is the input?


4. What are the products?

1. Lactic acid; glycolysis


2. Yeast and some plant cells.


3. Glucose.


4. Ethanol, CO2, 2 ATP.

What is the total ATP yield during fermentation?(anaerobic respiration)

2 ATP

What is the total ATP yield during aerobic respiration?

36 ATP

In order to enter cellular respiration:


1.polysaccharides are hydrolyzed to _________


2. Lipids are hydrolyzed to ______ and ______


3. Proteins are hydrolyzed to______

1. Glucose.


2. Glycerol & fatty acids


3. Amino acids

The main control point in glycolysis is __________ -allosterically inhibited by build up of ATP.

Phosphofructokinase

The main control point in the citric acid cycle is_______ - inhibited by NADH+, H+ and ATP.

Isocitrate dehydrogenase

Accumulation of citrate diverts _______ to fatty acid synthesis, for storage.

Acetyl COA

The most common in Fuel in organisms is

Glucose

Pyruvate oxidation


1. Where does this occur in the cell?


2. What is its general purpose?


3. What do we start with


4. What are the products?

1. Mitochondrial matrix.


2. Connects or links glycolysis to the citric acid cycle


3. 2 pyruvate.


4. CO2, 2 NADH

Citric Acid Cycle


1. Where does this occur in the cell?


2. What do we start with?


3. What are the products?

1. Mitochondrial matrix.


2. 2 acetyl COA.


3. CO2, FADH2, NADH, 2 ATP

Define Oxidative Phosphorylation

ATP is synthesized by reoxidation of electron carriers in the presence of 02. Occurs in the inner mitochondrial membrane

Electron Transport


Electrons from ______ pass through the respiratory chain of ____ which are than captured by _______ to form _______ .

Electron carriers


Membrane proteins


O2


H2O

What is the final electron acceptor?

Oxygen

What happens as electrons are passed down the respiratory chain

Proteins are pushed through the membrane

What is the proton motive force?

Accumulation of more hydrogen ions on one side than the other

Define chemiosmosis

The protons create a proton motive force, which drives them back across the membrane through ATP synthase, creating ATP.

Equation for metabolism of glucose

Glucose +oxygen—> CO2 + H20+ ATP

Reduction

Gain of one or more electrons buy an atom, ion or molecule

Oxidation

Loss of one or more electrons

_____ is a key electron carrier and redox reactions

Coenzyme NAD+

Oxidized form

NAD+

Reduced form

NADH

Glycolysis


1. Where does this take place in the cell?


2. What do we start with?


3. What are the products?

1. Cytosol


2. Glucose & 2 ATP


3. 2 pyruvate, 2 ATP, 2 NADH

Define substrate level phosphorylation

Enzyme catalyzed transfer of a phosphate group to ADP to form ATP

In which two steps of aerobic cellular respiration, does substrate level phosphorylation occur

1. Glycolysis


2. Citric acid cycle