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50 Cards in this Set

  • Front
  • Back

Long Bone

Long and slender


EX: Femur, Radius, and Phalanges



*Length is more than width*

Short Bones

Boxlike appearance


EX: Carpal and Tarsal bones

Flat Bones

Thin, parallel surface.


EX: Ribs, Scapula, Sternum,and Parietal bone.

Irregular Bones

complex shapes with short, flat, notched or ridged surfaces


EX: Spinal Vertebrae

Sesamoid Bones

Small, flat and sesame seed shaped; develops inside tendons.


EX: Patellae

Structural Bones


(Wormian Bones)

Small, flat, irregularly shaped bones between the flat bones of the skull.

Compact (Dense) Bone


Relatively solid; located on the surface of the bone.


*Forms a protective layer*


*Heavy Bone*

Spongy (Cancellous) Bone

Open network of struts and plates; interior or a bone.

Osseous Tissue

* Supporting connective tissue


* Contains specialized cells


* Solid matrix of extracellular protein fibers and a ground substance

Bone

1. Matrix is dense, contains calcium salt deposits.


2. OSTEOCYTES- Bone cells within LACUNAE -pockets


3. CANALICULI- Passageways through matrix that extend between the lacunae and nearby blood vessels.


4. PERIOSTEUM- Covers the outer surface if bone. (skin of the bone)

Calcium Phosphate

* Accounts for 66% of the weight of bone.


* Hard


* Relatively Inflexible


* Brittle


* Can withstan compression


* Shatter when exposed to bending, twisting, or sudden impact.

Collagen Fibers

* Accounts for 33% of the weight of bone


* Strong


* Flexible


* Tolerate twisting and bending


* Bend when compressed


(Can not handle weight)

Lacunae

(-cavities between lamellae – layer of


matrix)

Yellow Bone Marrow

has mainly fat cells and connective tissue; for lipid storage (energy reserve); occurs in medullary cavities of the long bones

Red Bone Marrow

Has mature/ immature red and white blood cells, and stem cells; blood cells formation; present ribs, vertebrae, sternum and bones of the pelvis, and ends of the humerus and femur.

Osteoprogenitor Cells

* Mesenchymal Cells


* Stem Cells


* Differentiate into osteoblast


* important in fracture repair


* Found in:


inner, cellular layer of the periosteum


inner layer (endosteum) that lines the marrow cavities


lining of vascular passageways in the matrix



Osteoblast


( Bone-Forming Cells)

* Modified fibroblasts


* Produce new bone matrix through osteogenesis


* Synthesize and release proteins and organic compounds that will become the bone matrix


* Help in elevating concentrations of calcium phosphate and deposition of calcium salt > converts OSTEOID (matrix prior to calcification) to bone


* Found beneath the periosteum and endosteum

Osteocytes


(Bone Cells)

* Most common cell


* Are osteoblasts that have become trapped in the lacuane( cavities between lamellae- layer of matrix)


* Two major functions:


> Recycle the calcuim salts in the matrix


> Participate in repair of damage bone; can convert into osteoblast or osteoprogenitor cell


Osteoclasts


* Larger than osteoblast


* Cause resorption of bone through osteolysis (by secretion of enzymes that digest the protein matrix of the one and release the minerals

Osteon


( Haversian System)

* Basic functional unit of a compact bone


* Contains osteocytes arranges around a central canal (runs parallel to the surface, contains blood vessels for the osteon)

Perforating Canals


( Canals of Volkmann)

Passageways that run perpendicular to the surface; contains blood vessels that supply blood to osteons deeper in the bone and to tissue of the marrow cavity.


( Allows blood to flow)

Lamellae

Layers of calcified matrix; arranged around the central canal.

Canaliculi

Within and between the lamellae interconnect the lacunae.

Compact Bone

Compact bone is thickest where stresses come from a limited range of directions, such as along the diaphysis of some bone.



Relatively solid; located on the surface of the bone.


*Forms a protective layer*


*Heavy Bone*

Spongy Bone

* Contains TRABECULAE- struts and plates of matrix, typically in open network


* No osteons


* No blood vessels


* Lighter than compact bone- reduces the weight of the skeleton ( easier to move around)



Located where stresses are few or come from many different directions, such as at the epiphyses of some bones.

Periosteum

* Covers all bones


* Fibrous outer layer and cellular inner layer


* Isolates the bone from surrounding tissues


* Provides a route for circulatory and nervous supply


* Participates in bone growth and repair.


* Near joints the periosteum becomes continuous with connective tissue that lock the bones together*

Perforating Fibers


( Sharpey's Fibers)

Collagen fibers incorporated into bone tissue from tendons and ligaments; provides a strong attachment.

Endosteum

* Cellular layer


* Lines the marrow cavity


* Covers the trabecular of spongy bone


* Lines the inner surface if the central canals


* Active during bone growth, repair and remodeling


* Flattened layer of osteoprogenitor cells that cover the bone matrix

Intramembranous Ossification

Bone developed from mesenchyme or fibrous connective tissue.


* Begins when osteoblasts differentiate within connective tissue


* Occur in the deeper layers of the dermis


* Results in dermal bones; EX- Flat bones of the cranium, mandible, clavicle


* Can develop bones in dermal areas or within tendons, joints, kidneys, skeletal muscle

Endochondrial Ossification

Bone replaces existing cartilage.


* Begins by forming a cartilage model


* cartilage model grows by


INTERSTITIAL GROWTH- Expansion of cartilage matrix


APPOSITIONAL GROWTH - Production of new cartilage at the outer surface


Nutrient Artery And Vein

Supply the diaphysis, enter through nutrient foramina; branches of these vessels extend along the length if the shaft.

Metaphyseal Vessels

Supply blood to the inner (diaphyseal) surface of each epiphyseal plate (where bone is replacing cartilage)

Periosteal Vessels

From the periosteum and become incorporated into bone tissue; provide blood to the superficial osteons of the shaft; also provide blood to the secondary ossification centers.

Remodeling

* Can replace the matrix if the bone and leave the whole bone unchanged


* Alter the shape, internal architecture or mineral content of the bone


* Involves the activities of osteocytes, osteoblast, and osteoclasts.


* Turn over rate is high


* Every part of the bone may or may not be affected


** Osteoblast make bone tissue**


** osteoclasts destroy bone tissue**

Parathyroid Hormone

Has three effects that increase calcium concentrations in the bloodstream ( decrease in calcium concentrations in bone tissue)


* stimulates osteoclast activity and amplifying recycling of minerals by osteocytes


* increase the rate if intestinal absorption of calcium ions by amplifying calcitriol action


* decreasing the rate of excretion of calcium ions at the kidneys

Calcitonin

Has two functions that lead to a decline in calcium concentrations in bloodstream ( increase in calcium concentration in the bone tissue)


* Inhibiting osteoclast activity


* Increasing the rate of excretion of calcium ions at the kidneys.

Longitudinal Growth

Is completed by age 17-19 in women although the attainment of adult height may be attained by ages 15-16 years.

Growth in Diameter

Bone diameter increases through appositional growth at the outer surface; while bone matrix is added to the outer surface, bone matrix is removed at the inner surface (bone marrow enlarges)

Ossification

Process of converting other tissues to bone.

Calcification

The process of depositing calcium salts within a tissue.

Growth of the skeletal determines....

Growth of the skeletal determines the size and proportions of our body

The age at which bone growth is....

The age at which bone growth is complete differs in men and women

Turnover and recycling of minerals give each bone....

Turnover and recycling minerals gives each bone the ability to adapt to stresses.

The shape and thicknesses of bones reflects the....

The shape and thicknesses of bones reflects the stresses applied to them.


EX: High stress bones become thicker and stronger

Calcium is the most...

Calcium is the most common mineral in the human body, with roughly 99% of it located in the skeleton.

Calcium ion concentrations are closely....

Calcium ion concentrations are closely regulated to prevent damage to physiological systems.

Interactions among the bones, intestinal tract...

Interactions among the bones, intestinal tract, and kidneys affect calcium ion concentrations.

Aging and the Skeletal System

* Bones become thinner and relatively weaker


* OSTEOPENIA - inadequate ossification


* Not all parts of the skeleton are equally affected: epiphyses, vertebrae, and jaw lose a lot of bone mass> fragile limbs, reduction in height, loss of teeth


* OSTEOPROSIS- reduction in bone mass is sufficient to compromise normal function -- Reduces sex hormones increases osteoporosis ( Women after menopause)


* OSTEOCLAST- ACTIVATING FACTOR- Chemical released by cancers of the bone marrow and breast; increased the number of and activity of osteoclasts; server osteoporosis

Hormones

* Calcitriol- Hormone that is necessary for normal calcium and phosphate ion asorption


* Growth Hormone- stimulates bone growth


* Thyroxine- Hormone stimulate cell metabolism and speeds up the osteoblasts activity.


* Sex Hormones at puberty- Over time their actions will narrow and close the epiphyseal plates.

Nutrients and hormones that are required for normal osteogenesis

* Calcitriol- Hormone that is necessary for normal calcium and phosphate ion asorption


* Growth Hormone- stimulates bone growth


* Thyroxine- Hormone stimulate cell metabolism and speeds up the osteoblasts activity.


* Sex Hormones at puberty- Over time their actions will narrow and close the epiphyseal plates.


* Calcium and phosphate salts: and other minerals


* Vit C- Needed for certain enzymatic reactions in making collagen


* Vit A- Stimulates osteoblast activity


* Vit K and B12- Synthesis of proteins