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10 Cards in this Set
- Front
- Back
What does theophylline prevent? What does theophylline control?
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Prophylaxis (prevention) and treatment of asthma, bronchospasm, maintenance therapy in COPD, and the apnea of premature neonates.
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Name the intravenous form of theophylline.
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aminophyline
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What is meant by the statement in the text, “Theophylline has a narrow therapeutic index”
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A drug with a narrow therapeutick index has a narrow safety margin. A drug with a low therapeutic index is more dangerous for patients because small increases over normal doses may be sufficient to induce toxic reactions.
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Name the two most common adverse effects of oral theophylline. Name three more
common side effects. |
Nausea and epigastric pain.
Headache, dizziness, and nervousness. |
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What has traditionally been used as the therapeutic range of theophylline?
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10-20 mcg/ml
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What serious and life threatening adverse effects may occur when the plasma concentration of theophylline exceeds the therapeutic range?
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Agitation, exaggerated reflexes, and mild muscle tremors are often seen.
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What other adverse reactions to theophylline may be seen in the therapeutic range?
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Seizures and arrhythmia.
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Name one group of clients that may require an increased dose of theophylline to be
effective. |
Smokers
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If gastric irritation is not present what is the preferred administration time of theophylline in
relation to meals? |
Before meals on an empty stomach
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Why should a person who is taking theophylline as maintenance therapy contact their health care provider before they quit smoking?
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The dose of xanthine may need to be adjusted.
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