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98 Cards in this Set
- Front
- Back
What two hypothalamic hormones control growth hormone secretion?
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Somatostatin (inhibits) GHRH (stimulates)
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Growth hormone needs what hormone to stimulate muscle and skeletal growth?
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IGF I
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Where is IGF I produced?
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the liver
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Hormone that informs CNS that adequate nutritional status and body fat mass are present to support pubertal changes and growth?
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leptin
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Hormone that enhances muscular development, sexual maturation, and promotes bone maturation and epiphyseal closure
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Testosterone
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Hormone that stimulates the development of female secondary sexual characteristics, linear growth by acceleration of skeletal maturation, and epiphyseal fusion
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Estrogen
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Androgens secreted by what tissue promote masculinization of the secondary sex characteristics and skeletal maturation?
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adrenal glands
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Stature is stationary between the ages of _____ and ____ before it begins to decline
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30 and 50
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Mean age of epiphyseal closure in males
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17. 5 years
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Mean age of epiphyseal closure in females
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14.5 years
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Skeletal growth continues until
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30 years of age
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By ______ years of age lymphatic tissues reach adult dimensions
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6 years of age
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By age _____ lymphatic tissues are at their peak, about double adult size
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10 - 12 years
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Most rapid and critical period of brain growth occurs between ______ and ______
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conception and 2 years of age.
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When are most of the neurons present in a human?
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18 - 20 weeks of gestation
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When are two thirds of the brain cells of a human present?
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at birth
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80% of brain growth is complete by what age?
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2 years
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Brain growth continues until about what age?
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12 to 15 years
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The head of an adolescent increases because of the development of what structures?
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air sinuses and thickening of scalp and skull
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New brain cell development is complete by what age?
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10 months
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Growth of the head predominates during which growth period?
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fetal
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When does fetal weight reach its peak?
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during the 3rd trimester (increase in organ size)
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During infancy the growth of________ predominates
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the trunk
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What part of the body is the fastest growing during childhood?
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the legs
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50% of an individual's ideal weight is gained during which growth period?
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adolescence
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Of adults who become obese ____ % are obese during childhood and _____ % are obese during adolescence
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30% and 70%
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During pregnancy the growing fetus accounts for only ____ to ____ pounds of total weight gained?
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5 - 10 pounds
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Rate of weight gain during pregnancy is slow during which trimester?
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the first
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Rate of weight gain during pregnancy is rapid during which trimester?
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the third
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What accounts for most of the weight gained in the first and second trimesters?
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maternal tissue growth
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What accounts for weight gained during the third trimester?
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Fetal growth
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Why do pregnant adolescents younger than 16, or less than 2 years after menarche, require higher weight gains during pregnancy to achieve an optimal infant birth weight?
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Those adolescents may still be in their growth spurt.
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Highly Sensitive period for neural tube defects and mental retardation?
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weeks 3 - 16 weeks
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Highly sensitive period for development of TA, ASD, and VSD?
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3 weeks - 7 weeks
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Highly sensitive period for development of Amelia/Mromelia?
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4 weeks to 6 weeks
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Highly sensitive period for low set malformed ears and deafness?
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4 weeks to 9 weeks
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Highly sensitive period for cleft lip?
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5 weeks to 7 weeks
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Highly sensitive period for microphthalmia, cataracts, and glaucoma?
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4 weeks to 8 weeks
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Highly sensitive period for enamel hypoplasia and staining?
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end of 6th week to 8 weeks
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Highly sensitive period for development of cleft palate?
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end of 6th week to beginning of 9th week
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Highly sensitive period for masculinization of female genitalia?
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mid 7th week to mid 9th week
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What causes the stature decline in older adults beginning at age 50?
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thinning of the intervertebral disks
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Correct way to measure standing height using scale?
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Have patient stand erect with back to scale, pull up height attachment to patient's crown
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Wrist circumference ratio
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patient's height in centimeters divided by wrist circumference in centimeters
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Male wrist circumference ratio of > 10.4
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small body frame
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Male wrist circumference ratio of > 10.4 - 9.6
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medium body frame
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Male wrist circumference ratio of < 9.6
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large body frame
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Female wrist circumference ratio of > 10.9
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small body frame
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Female wrist circumference ratio of > 10.9 - 9.9
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medium body frame
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Female wrist circumference ratio of < 9.9
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large body frame
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Percentage of Americans overweight?
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65% are overweight
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Percentage of Americans obese?
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30% are obese
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Percentage of Americans extremely obese?
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5% are extremely obese
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Measure of fat distribution by body type
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waist to hip circumference ratio
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Excess proportion of trunk and abdominal fat has higher risk association with what?
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diabetes mellitus, hyperlipidemia, stroke, ischemic heart disease
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When measuring the waist measure ?
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the midpoint between the costal margin and the iliac crest
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When measuring the hip measure ?
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Widest part of the gluteal region
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Waist to hip circumference ratio greater than ___ in men or _____ in women indicates increased risk of diabetes mellitus, hyperlipidemia, stroke, and ischemic heart disease
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1 in men and .85 in women
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Approximately ____ % of fat is subcutaneous?
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50% of fat is subcutaneous
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Babies with a larger birth weight than older siblings, at 10 pounds or greater, are at risk for what?
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acute lymphatic leukemia
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Recumbent length is measurement of choice for infants what ages?
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between 24 and 36 months
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Length increases by _____ % in the first year of life
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Length increases by 50%
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How often should you measure the infant's head circumference?
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at every health visit until 2 years of age, then yearly until 6 years of age
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Expected head circumferences for term newborns?
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32.5 - 37.5 cm
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A head circumference increasing rapidly and rising above percentile curves suggests?
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increased intracranial pressure
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At age 2 yrs a child's head circumference is _____ its adult size
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two-thirds
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Newborn's head circumference may equal or exceed the chest circumference by 2 cm for the first _____ of age?
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5 months
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Between the ages of 5 months and 2 years what is the relationship between the chest circumference and head circumference of an infant?
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about equal
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When should chest circumference exceed the head circumference?
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after 2 years of age
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Method of determining gestational age?
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number of completed weeks between the first day of mother's last menstrual period and date of birth
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Gestational ages of _____ - ______ are considered term
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37 weeks - 41 weeks
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An infant between the 10th and 90th percentiles is considered?
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appropriate for gestational age
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Children who have a weight for stature greater than the _____ percentile should be assessed with triceps skin fold thickness measurement
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90th percentile
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Formula for upper - lower segment ratio?
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(total height - lower segment measurement) divided by lower segment measurement
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How do you measure the lower segment?
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measure the distance from the symphysis pubis to floor
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Proper way to measure arm span?
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Distance from middle finger tip of one hand to that of the other hand.
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Arm span should equal a child's _____
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height
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Arm span that exceeds height is associated with what?
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Marfan Syndrome
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Tanner stage when dark curly pubic hair is first noticed on males?
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P3 tanner 3
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Tanner stage in which pubic hair is adult in type but does not pass inguinal fold?
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P4 tanner 4
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Tanner stage in which pubic hair is in adult distribution but does not spread upward?
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P5 tanner 5
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Peak height velocity occurs approximately how long before menarche in females?
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1 year
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Ejaculation generally occurs at SMR _____
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SMR 3
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Semen appears in ejaculate between SMR _____ and _____
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Between SMR 3 and 4
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Women with BMI of 19.8 - 26 should gain how much weight during pregnancy?
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25 - 30 pounds
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Women with BMI of 26.1 - 29 should gain how much weight during pregnancy?
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15 - 25 pounds
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Women who are obese should gain how much weight during pregnancy?
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15 pounds
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Underweight women should gain _____ pounds during the 1st trimester?
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5 pounds
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Overweight women should gain ____ pounds during 1st trimester?
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2 pounds
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Women with a twin pregnancy are recommended to gain how much weight during pregnancy?
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35 - 45 pounds
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Women with a triplet pregnancy are recommended to gain how much weight during pregnancy?
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50 pounds
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Gradual marked enlargement and elongation of bones of the face, jaw, and extremities are indicative of?
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Acromegaly
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Woman complains of facial feature changes and massive feet with no change in height over the last 7 years. Dx?
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Acromegaly
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Man comes in with muscle weakness, hyperpigmentation, fragile skin. He has centripetal obesity and an abdomen covered with striae. Dx?
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cushing syndrome
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An infant with an enlarging head, bulging fontanels and setting sun eyes is brought to your office. Dx?
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hydrocephalus
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A child is brought in with short, curved arms and longs. A long narrow trunk, midfacial hypoplasia and a prominent forehead. On exam you discover hypotonia secondary to what you think is spinal canal stenosis. Dx?
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Acondroplasia
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A child who was of normal size and weight at birth is brought in by his father because the child is growing slower than expected. At one year of age this child is several standard deviations below the mean for length and height. Dx?
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hypopituitary dwarfism
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A young woman comes in for a check up before her sophomore year of high school. On exam you notice a webbed neck, low posterior hairline, small mandible, epicanthal folds, high arched palate, and an increased carrying angle of the elbow. Remainder of exam unremarkable. Absence of what is caused these findings?
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absence of second X chromosome (Turner Syndrome)
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