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31 Cards in this Set

  • Front
  • Back

Skin: Functions

1.Protection - Cushions organs and protects from bumps, chemicals, water loss, UV radiation


2.Regulation of Body Temperature


3.Excretion - Urea, salts, and water lost through sweat


4.Sensory Reception - Receptors keep us aware of conditions at the body surface

Epidermis: 4 main cell types


Keratinocytes

Location: Stratum Spinosum



Produce keratin: fibrous protein that gives epidermis its protective properties


-also make antibodies, and enzymes



Most abundant cell type


Dead at skin surface

Epidermis: 4 main cell types


Melanocytes

Location: Basal Layer


Manufacture and secrete pigment


Secrete signaling molecules in response to UV radiation


-Modulate immune response in skin (tanning)


-Influence inflammatory response

Epidermis: 4 main cell types


Tactile Epithelial Cells

Location: Basal Layer


Attached to sensory nerve endings

Epidermis: 4 main cell types


Dendritic Cells

Location: Stratum Spinosum


Part of immune system; macrophage-like


-Monitor out body surface via receptor-mediated endocytosis (Antigens)


-Cells travel from skin to nearby lymph node

Layers of Epidermis (Lowest to highest)

Basale


Spinosum


Granulosum


Lucidum


Corneum

Layers of the Epidermis:


Stratum Basale

Deepest layer of epidermis


Attached to underlying Dermis


Cells actively Divide


Contains:


Merkel Cells - associated with sensory nerve ending


Melanocytes - secrete pigment melanin

Layers of the Epidermis:


Stratum Spinosum

"Spiny" appearance caused by:


Artifacts of histological preparation


Contains thick bundles of intermediate filaments


-Resists tension


-protein prekeratin


Contain star-shaped dendritic cells


-Macrophage


-Function in immune system

Layers of the Epidermis:


Stratum Granulosum

Consists of Keratinocytes and tonofilaments


Tonofilaments contain:


-Keratohyaline granules - help form keratin


-Lamellated granules - contain a waterproofing glycolipid

Layers of the Epidermis:


Stratum Lucidum

Occurs only in thick skin


Location of thick skin - palms and soles



composed of a few rows of flat, dead keratinoctyes

Layers of the Epidermis:


Stratum Corneum

Thick layer of dead keratinocytes and thickened plasma membranes



Protects skin against abrasion and penetration

Dermis

Second major layer of skin


Strong, flexible connective tissue


Richly supplied with blood vessels and nerves

Dermis: 2 layers

Papilary layer - dermal papilae


Reticular layer - Deeper layer, 80% thickness of dermis

Hypodermis

Deep to the skin, superficial fascia


Contains areolar and adipose connective tissue


Anchors skin to the underlying structures


Helps insulate body

Skin Color: 3 pigments

Melanin: Most important, made from tyrosine


Little found in caucasian skin



Carotene: Yellowish pigment from carrots and tomatoes



Hemoglobin: Allows crimson color of blood to show through

Nails

Made of hard keratin


Parts:


Free edge


Body


Root


Nail Folds


Eponychium - cuticle

Appendages of the skin:


Hair

Flexible strand of dead, keratinized cells


Hard keratin - tough and durable

Chief parts of hair

Root - imbedded in the skin


Shaft - projects above the skin's surface

Hair: Three concentric layers of keratinized cells

Medulla - central core


Cortex - surrounds medulla


Cuticle - outermost layer

Hair Follicles

Extend from Epidermis into Dermis

Hair Bulb

Deep, expanded end of the hair follicle

Root Plexus

Knot of sensory nerves around hair bulb

Arrector pili muscle

Bundle of smooth muscle


Hair stands erect when arrector pili contracts


Types of Growth of Hair:


Vellus Hairs

Body hairs of women and children

Types of Growth of Hair:


Terminal HAir

Hair of scalp


Axilary and pubic area (at puberty)

Sebaceous Glands

Occur over entire body (Minus palms/soles)


Secrete Sebum - oily substance


-Simple alveolar glands


-Holocrine secretion: Entire cell breaks up to form secretion


-Most associated with hair follicle

Functions of Sebum

Collects dirt


Softens and lubricates hair and skin

Sebaceous Glands:


Sweat Glands

Widely distributed throughout body

Sweat

Blood Filtrate


99% water with some salts


Contains traces of metabolic wastes


-2% Eurea

2 Types of Sweat Glands:


Eccrine Gland

Most numerous


These produce sweat

2 Types of Sweat Glands:


Apocrine Gland

Confined to axillary, anal, and genital areas


Produce special sweat


-musky odor to attract a mate



Ceruminous glands and mammary glands


-Modified apocrine glands