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54 Cards in this Set
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Codominance |
Where neither chemically diff. Version dominates the other |
(E.g.) blood type AB |
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Codons |
The sequence of 3 nitrogen bases that are carried by the MRNA that are coded to produce specific amino acids in protein synthesis.d |
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Diploid |
Somatic cells that have 46 chromosomes |
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Haploid |
Gametes with 23 chromosomes |
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Crossing over |
When homologous exchange parts when they pair up and intertwine |
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Gametes |
Sexual reproductive cells, ova and sperm, that have a haploid # of chromosomes and that can unite w/ a gamete of the opposite type to form a new organism |
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Genome |
All the genetic material in a person |
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Haplotypes |
Units/blocks of genetic material; a group of alleles that tend to be inherited as a unit due to their closely space loci on single chromosomes. |
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Heterozygous |
Chemically different alleles |
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Homozygous |
Chemically identical alleles |
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Meiosis |
The production of gamates through one DNA replication of 2 cells & nuclear divisions, creating four haploid game tic cells |
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Mitosis |
Production of new gametes (meiosis) the process of cellular and nuclear division that creates 2 identical diploid daughter cells |
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Zygote |
The cell that results from a superb fertilization of an ovum |
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Homologous |
Matching pairs of chromosomes; usually in somatic cells |
Chromosome type |
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Karyotype |
Complete set of chromosomes (including ALL autosomes and one pair of 5 chromosomes |
Chromosomes types |
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Autosomes |
All chromosomes excluding the mom/ dad chromosomes |
Chromosomes type |
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Genes |
Structural & regulatory |
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Structural gene |
Responsible for body structures like hair, blood & other tissues |
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Regulatory genes |
Turn other genes on and off; an essential activity in growth and development |
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Homeotic gene(hox) |
Regulatory genes that determine an organism’s form and the arrangement of its tissues and organs; considered mastered genes’ |
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Transcription |
1st step of protein synthesis, involving the creation of mRNA based on the DNA template usually takes place mostly, in the cells nucleus. |
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Transaction |
2nd step of protein synthesis, involving transfer of amino acids by tRNA to the ribosomes, which are then added to the protein chain- takes place in the cytoplasm |
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Ribonucleic acid (RNA) |
A single stranded molecule involved in protein synthesis, consisting of a phosphate, ribose sugar,& one of four nitrogen bases |
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Messenger RNA |
The molecules that are responsible for making a chemical copy of a gene needed for a specific protein that is, for the transcription phase of protein synthesis |
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Ribosomes |
The organelles attached to the surface of the endoplasmic reticulum leaded in the cytoplasm |
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Ribosomes RNA( rRNA |
A fundamental structural component of a ribosome; make up some of the ribosomes |
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Transfer RNA |
molecules that are responsible for trans pairing amino acids to the ribosomes during protein synthesis, float in the cytoplasm |
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Anticodons |
Sequences of three nitrogen bases that are carried by tRNA, they match up w/ the complementary mRNA codons, each designated a specific amino acids during protein synthesis |
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Peptide bond |
A chemical bond that joins amino acids held by Muriel peptide bonds |
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Coding DNA |
Sequences of a genes DNA (aka EXON) that are coded to produce a specific protein & are transcribed & translated during protein synthesis |
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Noncoding DNA |
Sequences of a genes DNA (aka INTRONS) that are not coded to produce specific proteins and are existed before protein synthesis |
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Polymorphism |
A genetic that (allele) that has 2 or more variants where the frequency is more than 1% |
E.g human blood type (refer to the human blood cell |
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Law of segregation |
Menedlu’s 1st law which asserts that 2 alleles for given gene (or gene ) are inherited, one form each parent during gamete production, only one of the 2 alleles w/ be present In each ovum/ sperm |
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Microsatellites |
Refers to the sequences of repeated base pairs of DNA usually no more than 2 to 6. Of repeated excessively, they are often associated w/ neurological disorders, such as Huntington’s chorea. |
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Polygenic |
Refers to one phenotypic trait that is affected by 2 or more genes |
Complexity of genetics |
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Pleiotrophy |
A single gene can have multiple affects |
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Epigenetic |
Refers to chemical changes in the genome affecting how the underlying DNA is used in the production of proteins, but without altering the DNA sequence |
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Methylation |
The attachment of a methyl group, a simple chemical to DNA @ certain sites throughout the genome. |
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Monosomy |
A loss in # of chromosomes |
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Non- disjunction |
When chromosome pairs fail to separate during meiosis/ mitosis |
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Recombination |
The exchange of genetic material b/w homologous chromosomes, resulting from a crossover event |
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Translocations |
Rare instances in which non- homologous chromosomes exchange segments during meiosis |
Most common one is chromosomes 13 & 14 |
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Patriline |
DNA whose inheritance can be traced from father to son via the Y chromosome |
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Heteroplasmic |
If can Differ among diff parts of a person’s body/ even within the same kinds of cells |
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Nucleotide |
Formed by sugar, phosphate and nitrogen base |
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Matriline |
DNA such as mitochondrial DNA whose inheritance can be traced from mother to daughter/so |
Is heteroplasmic Can be traced back hundreds and thousands of yrs. |
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mDNA |
Mitochondrial DNA containing 37 genes, is inherited JUST FROM THE MOTHER |
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ATP |
Created by the mitochondria, a high energy molecule that powers cells and in turn, powers every tissue in the body |
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Mitochondria |
Tiny organelles containing a small but significant amount of DNA |
Powerhouse of DNA These structures use oxygen to turn food molecules into ATP |
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Nucleus |
A membrane bound structure in eukaryotic cells that contains the genetic material cytoplasm |
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Somatic cells |
Body cells, compose most tissues such as bone, muscle, skin, & brain, lung, fat & hair |
Inner bone cells we have the DNA |
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Eukaryotes |
Multi celled organisms that have membrane bound nucleus; organisms w/ internal compartments separated by membranes |
Evolved much later than prokaryotes. Appearing 1.5 billion yrs ago |
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Prokaryotes |
Organisms having cells w/ no internal compartments |
Most life on earth ( 3.5 billion years ago Today they are single cell bacteria |
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Replication |
The process of copying nucleus DNA prior to cell division, so that each new daughter cell receives a complete complement of DNA and production of new somatic cells |
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