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54 Cards in this Set

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Codominance

Where neither chemically diff. Version dominates the other

(E.g.) blood type AB

Codons

The sequence of 3 nitrogen bases that are carried by the MRNA that are coded to produce specific amino acids in protein synthesis.d

Diploid

Somatic cells that have 46 chromosomes

Haploid

Gametes with 23 chromosomes

Crossing over

When homologous exchange parts when they pair up and intertwine

Gametes

Sexual reproductive cells, ova and sperm, that have a haploid # of chromosomes and that can unite w/ a gamete of the opposite type to form a new organism

Genome

All the genetic material in a person

Haplotypes

Units/blocks of genetic material; a group of alleles that tend to be inherited as a unit due to their closely space loci on single chromosomes.

Heterozygous

Chemically different alleles

Homozygous

Chemically identical alleles

Meiosis

The production of gamates through one DNA replication of 2 cells & nuclear divisions, creating four haploid game tic cells

Mitosis

Production of new gametes (meiosis) the process of cellular and nuclear division that creates 2 identical diploid daughter cells

Zygote

The cell that results from a superb fertilization of an ovum

Homologous

Matching pairs of chromosomes; usually in somatic cells

Chromosome type

Karyotype

Complete set of chromosomes (including ALL autosomes and one pair of 5 chromosomes

Chromosomes types

Autosomes

All chromosomes excluding the mom/ dad chromosomes

Chromosomes type

Genes

Structural & regulatory

Structural gene

Responsible for body structures like hair, blood & other tissues

Regulatory genes

Turn other genes on and off; an essential activity in growth and development

Homeotic gene(hox)

Regulatory genes that determine an organism’s form and the arrangement of its tissues and organs; considered mastered genes’

Transcription

1st step of protein synthesis, involving the creation of mRNA based on the DNA template usually takes place mostly, in the cells nucleus.

Transaction

2nd step of protein synthesis, involving transfer of amino acids by tRNA to the ribosomes, which are then added to the protein chain- takes place in the cytoplasm

Ribonucleic acid (RNA)

A single stranded molecule involved in protein synthesis, consisting of a phosphate, ribose sugar,& one of four nitrogen bases

Messenger RNA

The molecules that are responsible for making a chemical copy of a gene needed for a specific protein that is, for the transcription phase of protein synthesis

Ribosomes

The organelles attached to the surface of the endoplasmic reticulum leaded in the cytoplasm

Ribosomes RNA( rRNA

A fundamental structural component of a ribosome; make up some of the ribosomes

Transfer RNA

molecules that are responsible for trans pairing amino acids to the ribosomes during protein synthesis, float in the cytoplasm

Anticodons

Sequences of three nitrogen bases that are carried by tRNA, they match up w/ the complementary mRNA codons, each designated a specific amino acids during protein synthesis

Peptide bond

A chemical bond that joins amino acids held by Muriel peptide bonds

Coding DNA

Sequences of a genes DNA (aka EXON) that are coded to produce a specific protein & are transcribed & translated during protein synthesis

Noncoding DNA

Sequences of a genes DNA (aka INTRONS) that are not coded to produce specific proteins and are existed before protein synthesis

Polymorphism

A genetic that (allele) that has 2 or more variants where the frequency is more than 1%

E.g human blood type (refer to the human blood cell

Law of segregation

Menedlu’s 1st law which asserts that 2 alleles for given gene (or gene ) are inherited, one form each parent during gamete production, only one of the 2 alleles w/ be present In each ovum/ sperm

Microsatellites

Refers to the sequences of repeated base pairs of DNA usually no more than 2 to 6. Of repeated excessively, they are often associated w/ neurological disorders, such as Huntington’s chorea.

Polygenic

Refers to one phenotypic trait that is affected by 2 or more genes

Complexity of genetics

Pleiotrophy

A single gene can have multiple affects

Epigenetic

Refers to chemical changes in the genome affecting how the underlying DNA is used in the production of proteins, but without altering the DNA sequence

Methylation

The attachment of a methyl group, a simple chemical to DNA @ certain sites throughout the genome.

Monosomy

A loss in # of chromosomes

Non- disjunction

When chromosome pairs fail to separate during meiosis/ mitosis

Recombination

The exchange of genetic material b/w homologous chromosomes, resulting from a crossover event

Translocations

Rare instances in which non- homologous chromosomes exchange segments during meiosis

Most common one is chromosomes 13 & 14

Patriline

DNA whose inheritance can be traced from father to son via the Y chromosome

Heteroplasmic

If can Differ among diff parts of a person’s body/ even within the same kinds of cells

Nucleotide

Formed by sugar, phosphate and nitrogen base

Matriline

DNA such as mitochondrial DNA whose inheritance can be traced from mother to daughter/so

Is heteroplasmic


Can be traced back hundreds and thousands of yrs.

mDNA

Mitochondrial DNA containing 37 genes, is inherited JUST FROM THE MOTHER

ATP

Created by the mitochondria, a high energy molecule that powers cells and in turn, powers every tissue in the body

Mitochondria

Tiny organelles containing a small but significant amount of DNA

Powerhouse of DNA


These structures use oxygen to turn food molecules into ATP

Nucleus

A membrane bound structure in eukaryotic cells that contains the genetic material cytoplasm

Somatic cells

Body cells, compose most tissues such as bone, muscle, skin, & brain, lung, fat & hair

Inner bone cells we have the DNA

Eukaryotes

Multi celled organisms that have membrane bound nucleus; organisms w/ internal compartments separated by membranes

Evolved much later than prokaryotes. Appearing 1.5 billion yrs ago

Prokaryotes

Organisms having cells w/ no internal compartments

Most life on earth ( 3.5 billion years ago


Today they are single cell bacteria

Replication

The process of copying nucleus DNA prior to cell division, so that each new daughter cell receives a complete complement of DNA and production of new somatic cells