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38 Cards in this Set
- Front
- Back
Bioenergetics |
Transfer of energy from foodstuffs into biologically usable form Energy transfer in the cell occurs as a result of chemical reactions |
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Oxidation |
The process of removing an electron from an atom or molecule Molecule can't be oxidized unless it donates electrons to another atoms Oxygen tends to accept electrons and is an important property used by cells to produce a usable form of energy |
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NAD AND FAD |
vitamin b3 Vitamin riboflavin b2 Nad+= oxidized form |
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Enzymes How do they lower activation energy? |
Regulate the rate of speed at which the reaction takes place By forming an enzyme -substrate complex |
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Name factors that alter enzyme activity |
: temperature- have an optimum temperature at which they are active. When temperature increases so does the activity of enzymes, but an increase or decrease from the optimal temperature results in disassociate of the enzyme 2. Similar to ph. I.g accumulated hydrogen ions produced during heavy exercise decreases pH , therefore reducing enzyme activity |
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Carbohydrates fuel for exercise. What are they composed of? What are their forms? |
Carbon, hydrogen, and oxygen Monosaccharides Disaccharides, and polysaccharides Cells store glycogen, because if there was individual glucose molecules inside cells osmotic pressure between the inside of cell and outside fluid would change causing more water to come into cell |
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Fats |
Have a higher ratio of carbon to oxygen. Contain large quantities of energy per unit of weight |
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Four groups of fats |
Fatty acids---primary type of fat used by muscle cells for energy
Triglycerides Phospholipids Steroids |
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High energy phosphates ATP name the 3 parts: |
Adenine portion Ribosome portion 3 linked phosphates |
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Bioenergetics: muscle cells produce ATP three ways |
Formation of ATP by PC breakdown Degradation of glucose or glycogen Oxidative formation of ATP |
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PC to ADP forms ATP by: |
Donating phosphocreatine's phosphate group to ADP( aDiphosphate = 2 phosphates) |
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Glycolysis |
Breakdown of glucose or glycogen to form two molecules of pyruvate or lactate
Occurs in the sarcoplasm of the muscle cells |
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NAD+ |
Transport hydrogen In order for glycolysis to continue , two hydrogens must be removed from g3p and combines with inorganic phosphate to form 1,3 bpg. The hydrogen acceptor is NAD+. |
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How is NAD+ reformed from NADH? |
If enough oxygen is available, the hydrogen from NADH can be shuttled into the mitochondria of the cell contributing to ATP production. 2. Pyruvate can accept the h+ to form lactate if there is no oxygen available to accept them |
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Citric acid cycle-- Krebs cycle. What's the purpose of this cycle? |
Complete the oxidation of acetyl CoA using NAD+ and FAD as electron carriers The electron energy can be used in the ETC chain to combine AD + P to reform ATP |
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GTP |
Formed in the citric acid cycle Energy rich compound that can transfer its terminal phosphate group to ADP TO FORM Atp Small amount |
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How do fats and proteins undergo aerobic metabolism? |
Fats ( Triglycerides) are broken down to form fatty acids and glycerol. They undergo beta-oxidation to form acetyl coA and thus enter the citric acid cycle |
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ETC chain |
Occurs in the mitochondria Cytoxhrome chain Electrons removed from hydrogen atoms carried by transporter molecules are passed down the chain and energy is released to reform ATP |
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Why is oxygen necessary for the aerobic production of ATP? |
Allows the etc chain to continue working because of its ability to oxidize the last cytochrome in the chain. |
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Products of glycolysis |
2 ATP 2 NADH |
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Products of Krebs cycle |
2 GTP 6 NADH 2 FADH |
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Rate limiting enzymes |
They determine the speed of the particular metabolic pathway involved |
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Allosteric enzymes |
Enzymes regulated by modulators |
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Control of ATP-PC system "Negative feedback system" |
Phosphocreatine breakdown is regulated by creatine kinase Activated when there is an increase of ADP TRIGGERS THE breakdown of PC to resynthesize ATP |
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Primary role of the Krebs cycle |
Complete oxidation of substrates NADH and FADH to enter the ETC. the end result of the ETC Is the formation of ATP and water |
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Oxidation reduction reactions in cells often involve the transfer of ----- -‐---- ( with their electrons) rather than free electrons alone |
Hydrogen atoms |
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Enzyme substrate |
The shape of the enzymes active site must always fit for the binding substrates |
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List the four elements that make up 95% of the body |
Oxygen Carbon Hydrogen Nitrogen |
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Total of all cellular reactions and in ludes chemical pathways that result in the synthesis of molecules as well as the breakdown of molecules |
Metabolism |
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Glycogenolysis |
During exercise, individual muscle cells break down glycogen into glucose |
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T/f. Stored body fat is an ideal fuel for prolonged exercise because fat molecules contain large amounts of energy per unit of weight |
True |
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ATPase |
The enzyme that breaks the bond of ATP |
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The biochemical pathways that result in the production of ATP are regulated by precise control systems |
Each pathway contains a number of reactions that are catalyzed by specific enzymes. If ample substrate ( fats, carbohydrates. Proteins) is available, an increase in the number of enzymes present results in an increased rate of chemical reactions |
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Rate limiting enzyme in glycolysis pathway |
Phosphofructokinase |
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Phosphorylase |
Enzyme that degrades glycogen to glucose. Important for providing the glycolytic pathway with the necessary glucose at the origin of the pathway |
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Calcium importance: |
Each muscle contraction releases Ca+ is released from the sarcoplamic reticulum in the muscle. This indirectly activates enzymes to break down glycogen to glucose |
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Isocitrate dehydrogenase |
Rate limiting enzyme in the citric acid cycle, inhibited by ATP and stimulated by high levels of ADP + Pi |
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High levels of ATP inhibit further ATP production, and high levels of ADP +Pi stimulate ATP production |
True |