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27 Cards in this Set

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What does the cell theory state?

Cells are building blocks of all plants and animals.

All cells come from the division of previous cells. Cells are the smallest units that perform all vital functions.


Each cell maintains homeostasis at cellular level

What are the two Classes of cells?
Sex Cells Germ cells-

reproductive cells Sperm (male cells)


Oocytes (female cells)


Contain 23 chromosomes -




Somatic cells All other cells within chromosome 46 chromosomes (23 pairs)

What is found in the cytoplasm

Cell contents


Subdivided into


Cytosol: intracellular fluid Organelles: Intracellular structure

extracellular fluid?
Surrounds cell Watery fluid

What are the roles of membrane lipids

Lipids (Fatty Acid Tails) form most of surface area (42%)


Prevent water soluble molecules from passing through membrane


Lipid soluable molecules CAN pass through


Small gases and water can squeeze between fatty acid tails through membrane

Role ofMembrane Proteins

Accounts for 55% of PM


Anchoring Proteins -Attach to PM and other structures (cytoskeleton, extracellular fibers)


Recognition Proteins-


Often glycoproteins


Help to ID normal vs abnormal cells


Enzymes


Catalyze membrane bound reactions


Receptor Proteins


Binds with ligand (hormones) triggers changes in cellular activity


Carrier Proteins


Bind solutes and transport across PM


Channels


Central Pore forms passageway- permits movement of water and small solutes across PM

What are the different types of membrane proteins?

Integral Proteins=transmembrane Proteins


Part of membrane, cannot be removed without damage to PM


Most span width of PM




Peripheral Proteins


Bound to inner or outer surface Easily separated Fewer than integral

What are the roles of membrane carbohydrates?

Accounts for only 3% of PM Components of more complex molecules such as: Proteoglycans, glycoproteins, and glycolipids


Extend beyond outer surface of membrane forming a layer called: Glycolax


Function as: Lubrication and protection of PM


Anchoring and location of cell


BINDS extracellular compounds altering cell surface and indirectly cell behavior


Involved in Immune response

List the functions of the plasma membrane and the structural features that enable it to perform those functions

Physical Isolation


Regulation of Exchange within environment


Eliminate waste


controls entry of nutrients


Sensitivity to environment


Contains receptors to recognize molecules


Structural Support




Structural Features:


Phosphate heads Hydrophilic


Fatty Acid Tails Hydrophobic

What types of molecules can diffuse across plasma membrane?

Non polar, hydrophobic molecules

Alcohols, fatty acids and steroids


Dissolved gases: O2 and CO2


Soluble in lipids

What types of molecules cannot diffuse across plasma membrane?

Polar molecules and ions


Water soluable


Require protein to aid in transportation

What types require a protein channel or protein transporter to cross plasma membrane?


Polar molecules and ions



Water soluable

What is it meant by having a cell membrane that is selectively permeable?


Based on size, electrical charge, molecular shape lipid solubility



Also based on PM structure

Describe the processes of cellular diffusion


Random movement of molecules from high to low concentration



Eventually eliminates concentration gradient and becomes evenly distributed

Describe process of cellular osmosis


Movement of water molecules across membrane from HIGH WATER concentration to LOW WATER concentration



Happens when membrane is selectively permeable to water, but not solutes



Eliminates solute concentration differences faster than diffusion

What factors are involved in the diffusion rate across cell membrane?


Shorter distance, faster diffusion



Molecule size: Smaller size, faster diffusion



Temperature: higher temp, faster diffusion



Gradient size: greater concentration gradient, faster diffusion



Electrical Forces: opposites attract

Describe carrier mediated transport


Can be passive or active



Requires integral memebrane proteins



What are characteristics of carrier mediated transport?


Each carrier protein binds and transports specific substances



Saturation limits:



Availibility of substrate molecules and carrier proteins limit transport rate



When all carrier proteins are filled: saturation



Regulation:



Binding of other molecules can effect activity of carrier protein



Two types:



Facilitated Diffusion



Active Transport

What is vesicular Transport? What are the to main types?


Move materials in or out of cell in vesicles "bulk transport"



2 Main Types



Endocytosis



Pinocytosis: cell drinking



Phagosytosis: cell eating



Exocytosis



Movement out of cell

What is active Transport? How is it different from other types of transport?


Active transport is different because it requires ATP



It moves substances against concentration gradient (from low to high)



Details:



Solute attaches to specific binding site on transport protein



ATP phosphorylates the transport protein, causing it to change so solute is released on other side of protein



Phosphate group detaches, transport protein returns to original shape, ready for more ACTIVE TRANSPORT!!!

Describe the Na/K- exchange pump. Which type of transport is it an example of?


Na and K- are principle cations in body fluids



Pump maintain resting ion levels



Na high in the extracellular fluid (low in cytoplasm)



K is high in INTRACELLULAR fluid (low in extracellular)



Na diffuses in, K out



As ions leak, pump restores required resting levels



Takes 3 Na to outside



Takes 2 K to inside



One ATP per 3Na/2K

Na/K- exchange pump Pic

What are the different types of endocytosis? How are they different from one another?


Pinocytosis



Endocytosis of extracellular fluid



Common to most cells



Phagocytosis



Endocytosis of solid objects



Common with WBC's



Objects include bacteria, cell debris



What is tonicity? And osmolarity


Describes how a solution affects a cell



Osmolarity is solute concentration in aqueous cell

What is an isotonic solution

Intracellular environment and extra have equal osmolarity
Hypertonic solution?


Solution has greater content than cell



Water will leave cell via osmosis, shrinking and dehydrate

Hypotonic Solution?


Solute has less solute concentration than cell



Water will enter cell vis osmosis, swell, potential hemolysis