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80 Cards in this Set
- Front
- Back
Upper Respiratory System
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Nose, pharynx
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Lower Respiratory System
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Larynx, trachia, bronci, lungs
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Conducting Zone does what? what structures are assosiated with it?
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Conducts air to the lungs, nose pharynx larynx trachea bronchi bronchioles and terminal bronchioles
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Respiratory Zone does what?
Structures? |
Main sight of gas exchange; respiratory bronchis, alveolar ducts, alveolar sacs, alveroli
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Nose; Functions
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Cleans
Humidifies Speech Olfactioin |
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Pharynx; Functions
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Air and food passageway
Resonating Chamber Houses tonsils |
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Larynx Function
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Sound production
opening to lungs, glottis |
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Trachea
location layers rings? |
extends from larynx to T5
Mucosa Submucosa Hyline Cartildge Adventitia 16-20 C shaped rings of cartildge |
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Bronchi
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Right and left primary bronchi goes to right lung.
Divide to form bronchi tree |
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Carina
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interal ridge of bronchi
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Structural changes with branching bronchi
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mucus membrane changes
incomple rings become plates then disapear as cartidge decreases smooth muscle increases Sympathetic:relaxation/dialation Parasympathetic:contraction/constriction |
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Lung
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seperated by eachother by the heart
each lung has a double layer pleural membrane |
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Parietal Pleura
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lines wall of thorasic cavity
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Viseral Pleura
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covers the lung
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Pulmonary Ventilation
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Breathing
inhalation/exhalation exchange of air between atmosphere and alveoli |
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External Respiration
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exchange between alveolar air and pulmonary capillary blood
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Internal respiration
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exchange between systemic blood capllarys and blood tissue
makes ATP |
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Diaphram
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most important muscle of inhalation
responisble for 75% of air going to lungs |
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External intercoastals
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responsible for 25% of air going to lungs
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What happens when the thorax expands?
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parietal and viseral pleura adhere to eachother due to subatmospheric pressure and suface tension
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Pressure in lungs is greater then
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Atmospheric Pressure
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Normally Passive
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Muscle relaxtion
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What is the normally passive process based on? how does it work?
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based on the elastic recoil of chest wall and lung from elastic fibers surface tension
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During exhalation what do the diaphram and intercoastals do?
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Diaphram relaxes and becomes dome shaped
Intercoastals relax and ribs drop down |
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Exhalation is only active during..
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forcefull contraction
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Boyles Law
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States that as volume increase pressure decrease or vice versal
During inhalation: the diaphram contracts, lungs move outward and there is an increase in alveolar pressure During exhalation; diaphram relaxes, lungs recoil inward, decrease in alveolar pressure |
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Daltons Law
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every gas in a mixture of gases has its own partial pressure as if there were no other gasses.
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Partial Pressure
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Pressure of a specific gas
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Total Pressure
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sum of all the partial pressures
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Atmospheric pressure
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760mmHg. what are the partial pressures involved?
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Henrys Law
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quantity of gas that will dissolve in a liquid is proportional to the partial pressures and solubiltiys of that gas
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What will the gas do if it has a high partial pressure and high solubilty?
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It will stay in the solution
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Why does CO2 dissolve in blood better than O2?
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It is 24 times soluble than O2
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How come we breathe in N2 more than any other gas but it does not stay in our blood?
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it is not very soluble
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External Respiration
Oxygen diffusion |
Only in the lungs
o2 diffuses from alveolar air (105) to pulmonary capillaries (40) |
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during external respiration, o2 diffuses untill..
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the p02 of pulmonary cap. (40) reaches the same p02 of alveolar air (150)
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What does the small amount of mixing with respiratory system do to the pulmonary veins?
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drops the Po2 to 100
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What is CO2 doing during external respiration?
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diffusing from pulmonary capillaries(45) to alveolar air (40)
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When will the diffusion of CO2 of external respiration stop?
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when the pCO2 of the blood reaches 40
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Internal Respiration
Diffusion of O2 |
O2 diffuses from systemic capillarys(100) to tissue cells (40)
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why is there such a difference in po2 with internal respiration
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becasue it is constantly making ATP
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Internal Respiration;
what does blood do till when it exits the system capillaries? |
Its po2 drops to 40mmhg
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CO2 diffusion of Internal Respiration
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co2 diffuses from tissue cells (45) to systemic capillaries (40)
it is constanly making CO2 |
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At rest, how much O2 is used?
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25%
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how much does deoxygentated blood retain of its oxygen capacity?
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75%
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during external respiration, o2 diffuses untill..
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the p02 of pulmonary cap. (40) reaches the same p02 of alveolar air (150)
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What does the small amount of mixing with respiratory system do to the pulmonary veins?
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drops the Po2 to 100
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What is CO2 doing during external respiration?
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diffusing from pulmonary capillaries(45) to alveolar air (40)
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When will the diffusion of CO2 of external respiration stop?
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when the pCO2 of the blood reaches 40
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Internal Respiration
Diffusion of O2 |
O2 diffuses from systemic capillarys(100) to tissue cells (40)
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why is there such a difference in po2 with internal respiration
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becasue it is constantly making ATP
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Internal Respiration;
what does blood do till when it exits the system capillaries? |
Its po2 drops to 40mmhg
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CO2 diffusion of Internal Respiration
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co2 diffuses from tissue cells (45) to systemic capillaries (40)
it is constanly making CO2 |
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At rest, how much O2 is used?
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25%
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how much does deoxygentated blood retain of its oxygen capacity?
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75%
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What does Gas Exchange Depend on?
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Partial Pressures of gases
Surface Area Diffusion distance molecular weight and solubility |
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Alveolar pressure must be WHAT compared to Blood P02 for diffusion to occur?
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greater
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What is the most important factor that determines how much O2 binds to hemoglobin?
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the PO2. The higher the PO2 the more O2 binds to hemoglobin
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Fully Saturated
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means that hemoglobin is completley converted to ohyhemoglobin
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Percent Saturated of Hemoglobin
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the average saturation of oxygen with hemoglobin
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In pulmonary capilaries O2 loads or unloads onto a hemoglobin
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load
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in tissues, 02 loads or unloads with Hb
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unloads
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Other factors that affect affinity of hemoglbin for oxygen
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Acidity
PCO2 Tempurature |
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Acidity
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as acidity increases (pH decreases) the more O2 unloads off of hemoglobin
-increased acidity enhances unloading -shift curves to the right |
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PCO2
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as PCO2 rises, Hb unloads O2 more easily
-shifts to the right -Low blood pH can result from high PCO2 |
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Tempurature
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As temp increases the affinity for hemoglobin and oxygen decreases O2 is released
high temp-shift to the right low temp-shift to the left |
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2,3 Biphosphoglycerate (BPG)
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formed in RBC in glycolysis
helps unload O2 by binding with Hb |
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CO2 Transport
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-7% is dissolved in plasma
-23% carbamino acid, carbamindohemoglobin -70% transported as bicarbonare ion HCO3 |
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Respiratory Structures In BrainStem
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Medullary respiratory center
Pontine respiratory groups |
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Medullary Respiratory Center
(dorsal, ventral) |
Dorsal groups stimulte diaphram
Ventral groups stimulate intercoastals and abdominals |
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Pontine Respiratory Group
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involved in the switching of insparation and expiration
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Modification of Ventilation
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Apnea
Hyperventilaion Cerebral and limbic system |
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Apnea
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censation of breathing can be consciously controlled
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Hyperventilation
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causes decrease in blood PCO2 level
Fainting Peripheral vasodialation causes decrease in BP |
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Chemoreceptors
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specialized nuerons that respond to changes in chemicals in solution
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Central Chemoreceptors
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chemosensitive area of the medulla; connected to respiratory center
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Peripheral Chemoreceptors
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corotid and aortic bodies; connected to respiratory center by cranial nerves IXand X
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Chemosensitive areas responde ___ through changes in CO2
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Indirectly
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Peripheral Chem. responde ____-through changes of pH
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directly
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Hypoxia
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decrease in oxygen levels below normal values
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