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12 Cards in this Set
- Front
- Back
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What are the two drugs that imply a mood variance according to biogenic amines? Why do they have such implications?
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1) Reserpine produces depression. It depletes biogenic amines (Norephinephrine, 5-HT)
2) Iproniazid elevates mood. It inhibits Monamine Oxidase (MAO), possibly potentiating biogenic amine action. |
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Name four different treatments for depression.
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TCAs (Tricyclic Antidepressants), MAO inhibitors, SSRIs (Selective Serotonin Reuptake Inhibitors), and ECT (Electroconvulsive Therapy).
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What are three types of treatment for manic-depression?
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DA receptor blockers (haloperidol, olanzapine) for acute.
Lithium for chronic. Anticonvulsants like valproate. |
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What is the term to describe agents that reduce anxiety?
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Anxiolytic
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The ___ can help activate the ___'s release of CRH, with subsequent cortisol release from the ___ ___.
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Amygdala, hypothalamus, adrenal glands
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Describe an experiment with the startle response.
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Measure a control group animal's reaction to a startling stimulus as compared to the reaction to the same stimulus when the animal is in a stressful condition (such as the presence of a something associated with pain).
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Who coined the term "Schizophrenia?"
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Eugen Bleuler
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What is the difference between Type I and Type II schizophrenia?
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Type I shows symptoms such as hallucinations, paranoia, and delusions.
Type II shows symptoms such as emotional "flatness," social withdrawal, and anhedonia (the inability to feel pleasure). The two also have differences in chemical treatment. |
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For what disorder are Fluphenazine, Haloperidol, Parazine, and Pimozide all treatments?
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Schizophrenia.
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What are common side effects of schizophrenia drugs that work through blockage of DA?
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Parkinsonian effects, Tardive Dyskinesia (involuntary movement, especially of the face) probably result from blockage of DA in the basal ganglia.
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How can motor problems associated with treatments for schizophrenia currently be avoided or lessened?
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By using drugs that target DA receptors outside of the basal ganglia.
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At what neurotransmitter and receptor is new research of schizophrenia treatment directed? What drug suggests this path and why?
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Glutamate, NMDA
PCP, because it acts to block NMDA receptors and can induce schizophrenic symptoms. |
