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358 Cards in this Set

  • Front
  • Back
What is the function of the central nervous system?
coordination and control of the body
What is the function of the peripheral nervous system?
carries information to and from the central nervous system
What is the function of the autonomic nervous system?
coordinates and regulatesthe internal organs of the body like the cardiac and smooth muscle
What is the function of the sympathetic division?
prods the body into action during times of physiologic and psychologic stress
What is the function of the parasympathetic division?
conserve body resources and maintain day to day body functions such as digestion and elimination
What does the interrelationship of the nervous system permit the body to do?
-receive sensory stimuli from the environment
-identify and integrate the adaptive processes needed to maintain current body functions
-orchestrate body function changes required for adaptation and survival
- integrate the rapid responsiveness of the CNS with the more gradual responsiveness of the endocrine system
- control cognitive and voluntary behavioral processes
- control subconsciousness and involuntary body functions
how many layers of meninges surround the brain and spinal cord?
3
where does the brain receive its blood supply from?
2 internal carotids
2 vertebral arteries
how does the blood drain from the brain?
travels through venous plexuses and dural sinuses that empty into thee internal jugular veins
What is the function of the cerebral cortex?
general movement, visceral function, perception, behavior, and the integration of these functions
What is the function of commissural fibers
interconnect the counterpart areas in each hemisphere permitting the coordination of activities between the hemispheres
What is the function of the frontal lobe?
voluntary skeletal movement and fine repetitive motor movements as well as control of eye movement
What is the function of the parietal lobe?
processing sensory data as it is received with the interpretation of tactile sensations, as well as visual, gustatory, olfactory, and auditory sensations

recognition of body parts and awareness of body position (proprioception)
What is the function of the occipital lobe?
primary vision center and provides interpretation of visual data
What is the function of the temporal lobe?
perception and interpretation of sounds and determination of their source

integration of taste, smell, and balance
Where is the reception of speech and interpretation of speech located?
Wernicke area
What is the function of the basal ganglia
processing station between the cerebral motor cortex and upper brainstem

refine motor movement
What does the cerebellum work with to carry out its function?
aids the motor cortex of the cerebrum in the integration of voluntary movements

processes sensory information from the eyes, ears, touch receptors, and musculoskeletal

works with the vestibular system to use the sensory data for reflexive control of muscle tone, balance and posture to produce steady and precise movements
What is the function of the thalamus
integrating center for perception of various sensations such as pain and temperature

relays sensory aspects of motor information between the basal ganglia and cerebellum
What is the function of the pons?
transmits information between the brainstem and cerebellum relaying motor information from the cerebral cortex to the contralateral cerebellar hemisphere
Where does the descending corticospinal tract decussate (cross to the contralateral side)?
medulla oblongata
What cranial nerves are sensory?
olfactory
optic
acoustic
What cranial nerves are motor?
oculomotor
trochlear
abducens
spinal accessory
hypoglossal
What cranial nerves are both motor and sensory?
trigeminal
facial
glossopharyngeal
vagus
What nerves are associated with the medulla oblongata and what is its function?
CN IX TO XII
-respiratory, circulatory, and vasomotor activities, houses respiratory center
- reflexes of swallowing, coughing, vomiting, sneezing, and hiccuping
- relay center for major ascending and descending spinal tracts that decussate at the pyramid
What nerves are associated with the pons and what is its function?
CN V TO VIII
-reflexes of pupillary action and eye movement
- regulates respiration; houses a portion of the respiratory system
- controls voluntary muscle action with corticospinal tract pathway
What nerves are associated with the midbrain and what is its function?
CN III AND IV
- reflex center for eye and head movement
- auditory relay pathway
-corticospinal tract pathway
What nerves are associated with the diencephalon and what is its function?
CN I AND II ALSO RELATED TO THALAMUS
- relays impulses between cerebrum, cerebellum, pons and medulla
- conveys all sensory impulses
- integrates impulses between motor cortex and cerebrum
- controls state of consciousness, conscious perceptions of sensations and abstract feeling
What is the function of the epithalamus?
houses the pineal body

sexual development and behavior
What is the function of the hypothalamus?
major processing center of internal stimuli for autonomic nervous system
-maintains temperature control, water metabolisms, body fluid osmolarity, feeding behavior and neuroendocrine activity
What is the function of the pituitary gland?
hormonal control of growth, lactations, vasoconstriction, and metabolism
Where does the spinal cord begin and end?
at the forament magnum and terminates at L1 or L2
What is found in the gray matter of the spinal cord?
sensory pathways and autonomic nervous system
What is found in the white matter of the spinal tract?
ascending and descending spinal tracts
What is the functions of the ascending tracts?
carry sensation
What is the function of the posterior dorsal column tract?
carries the fibers and sesnsations of fine touch, two point discrimination and proprioception
What is the function of the spinothalamic tract?
carry the fibers for sensation of light and crude touch, pressure, temperature and pain
What is the function of the descending spinal tract?
convey impylses to various muscle groups by inhibiting or exciting spinal activity
What is the function of the corticospinal tract?
permits skilled, delicate and purposeful movement
What is the function of the vestibuulospinal tract?
cause the extensor muscles of the body to suddenly contract when an individual starts to fall
What is the function of the corticobulbar tract
innervates the motor function of the cranial nerves
Where are upper motor neurons
nerve cell bodies for motor pathways that originate and terminate within the CNS
What is the role of upper motor neurons
influence, direct, and modfiy spinal reflex arcs and circuits
Where are the lower motor neurons?
originate in the anterior horn of the spinal cord and extend into the peripheral nervous system?
What is the function of lower motor neurons
transmit neural signals directly to the muscles that permit movement
injury to upper or lower motor neurons results in permanent paralysis?
lower motor neurons
what word describes the specific body distribution of a spinal nerve?
dermatome
what is located in the anterior root of the spinal cord?
motor or efferent fibers of the anterior root carry impulses from the spinal cord to the muscles and glands of the body
What is located in the posterior root of the spinal cord?
sensory or afferent fibers carry impulses from sensory receptors of the body to the spinal cord, and then on to the brain for interpretation by the cerebral sensory cortex
How does the reflex arc work?
spinal afferent neuron initiates reflex when receives an impulse stimulus

response is transmitted via the efferent neuron in the anterior horn stimulation a brisk contraction

its dependent on intact afferent neurons, functional synapses of the spinal cord, intact efferent neuron, functional neuromuscular junctions and competent muscle fibers
When occurs to the nervous system during the first year of life?
majority of brain growth and also have myelinations of the nervous system
What inhibits the primitive brain reflexes?
advanced cortical functions and voluntary control begin to take over
In what direction does motor maturation develop?
cephalocaudal direction
What changes occur in pregnancy to the nervous system?
hypothalamic pituitary neurohormonal changes. tend to increases sleep time even though they dont feel rested
What are risk factors for stroke?
hypertension
obesity
sedentary lifestyle
smoking tobacco products
stress
increased levels of serum cholesterol, lipoproteins and triglycerides
use of oral contraceptives
sickle cell anemia
family history of diabetes mellitus, cardiovascular disease, hypertension and increased serum cholesterol levels
congenital cerebrovascular anomalies
What are risk factors for falls in older adults
one or more fall in the past year
past history of stroke
neurologic condition like Parkinson disease, dementia or peripheral neuropathy
disorder of gait or balance
lower extremity weakness or sensory loss
impaired vision
use of an assistive device
What is the procedure for the neurologic exam?
cranial nerves
proprioception and cerebellar function
sensory function
deep tendon reflexes
How do you test the olfactory nose
test ability to identify familiar orders one naris at a time with the eyes closed
How do you test the optic nerve?
vision with eye charts
perform opthalmic exam of fundi
How do you test the Occulomotor, trochlear, and abducens nerve?
inspect eyelids for dropping
inspect pupils size for equality and their direct and consensual response to light and accomodation
test extrocular eye movement
How do you test the trigeminal nerve?
inspect face for muscle atrophy and tremor
palpate jaw muscle for tone and strength when patient clenches their teeth
test superficial pain and touch sensation of each branch
test corneal reflex
How do you test the facial nerve?
inspect symmetry of facial feature with various expression (smile, frown, puffed cheeks, wrinkled forehead)
test ability to identify sweet and salty tastes on each side of the tongue
How do you test the acoustic (vestibulocochlear) nerve?
sense of hearing with whisper screening test or audiometry
compare bone and air conduction of sound
How do you test the glossopharyngeal and vagus nerve?
test ability to identify sour and bitter tastes
test gag reflex and ability to swallow
inspect palate and uvular for symmetry with speech sounds and gag reflex
observe for swallowing difficulty
evaluate quality of guttural speech sounds
How do you test the spinal accessory nerve?
test trapezius muscle strength
test SCM muscle strength
How do you test the hypoglossal nerve?
inspect tongue in mouth and while protruded for symmetry, tremors and atrophy
inspect tongue movement toward nose and chin
test tongue strength with index finger when tongue is pressed against the cheek
evaluate quality of lingual speech sounds
Which nerve is one of the first to lose function with increased intracranial pressure?
CN VI abducens
how do you differentiate between an upper and lower motor neuron lesions of the face?
when the upper motor neurons are affect voluntary movement are paralyzed but emotional movements are spared (still able to move forehead) in lower motor neuron disorder all facial movements on the affected side are paralyzed
How do you test vestibular function?
Romberg test
What involuntary movements should you search for while doing a neurologic exam
tremors, tics of fasciculations
How do you test rapid rhythmic alternating movements?
seated patient taps with both hands, alternately turning up and down the palms of the hands

patient touch the thumb to each finger of the same hand
How do you test accuracy of movements?
finger to finger test, finger to nose test, heel to shin test with the eyes open

movement should by rapid, smooth, and accurate

needs to be done bilaterally
tremor seen with arms held extended, disappears when limb is at rest, small amplitude
enhanced physiolgic tremor
What causes an enhanced physiologic tremor?
drug or alcohol withdrawal
hyperthyroidism, hyperglycemia
drug toxicity
what tremor is bilateral symmetric and primarily seen in hands or outstretched arms
essential tremor
What are potential causes of essential tremor?
no consistent cerebral pathology but may have an autosomal dominant inheritance pattern
What will worsen an essential tremor
stress or fatigue
What will improve an essential tremor?
alcohol
What type of tumor is seen during intentional movements?
intention tremor
What are potential cause of intention tremor?
cerebellar disorder like MS or alcohol abuse
What type of tremor is seen with a limb at rest with slow supination and pronation movements
resting tremor
What causes a resting tremor
Parkinson disease
How do you initially evaluate balance?
Romberg test
What does a positive romberg sign indicate?
cerebellar ataxia
vestibular dysfunction
sensory loss
What should be continuously noted observing the patients gait?
continuously sequence stance and swing step after step
gait pattern where the affected leg is stiff and extended with plantar flexion of the foot, the foot is typically dragged or circumduction and the affect arm is flexed and adducted and does not swing
spastic hemiparesis
gait pattern where the patient uses short steps, dragging the ball of the foot across the floor
spastic diplegia (scissoring)
What causes spastic diplegia?
injury to the pyramidal system
What gait is associated with the hip and knee are excessively elevate d high to lift the plantar flexed foot off the ground, the foot is brought down to the floor with a slap and the patient is unable to walk on heels
steppage gait
What gait is associated with legs kept far apart and weight shifted from side to side in waddling motion
dystrophic gait
What causes dystrophic gait?
weak hip abductor muscles
What gat is associated with the legs position far apart and the heel stamps on the ground with each step?
tabetic gait
What gait is associated with the feet wide based, staggering and lurching from side to side and often accompanied by swaying of the trunks
cerebellar gait
What gait is associate with wide base, feet are thrown forward and outward bringing them down first on heels then on toes and the patient watches the ground to guid his steps
sensory ataxia
What gait is associated with short shuffling steps and with hesitation on starting and difficulty stoppin
Parkinsonian gait
What gait is associated witth jerky, dancing movments appear nondirectional
dystonia
What gait is assocaited with uncontrolled falling
ataxiaa
What gait is associated with the patient limiting the time of weight bearing on the affected leg to limit pain
antalgic limp
What are expected findings to find testing sensory stimulus bilaterally
minimal difference side to side

cprrect interpretation of sensation

discrimination of the side of body tested

location of sensation and whehter proximal or distal to previous stimuli
What is used to test primary sensory functions?
supperficial touch
supperficial pain with light and sharp touch
temperature differnce
deep pressure
vibrations and position of joints
What may loss of sensory modalities indicated?
perippheral neuropathy
What does symmetic sensory loss indicate
polyneuropathy
What does cortical or discriminatory sensory functions test?
cognitive ability to interpret sensation

suspect lesions in posterior column of spinal cord
How do you test stereognosis?
hand patient familiar object and have them identify the object baed on touch and manipulation
How do you test extinction phenomenon
simultaneously touch two areas on each side of body with sharp edge and have patient tell you haw many stimuli there are and where they are
How do you test graphesthesia?
with blunt pen or applicator draw letter number or shape on patients hand and have them identify it
What is the pattern of sensory loss with a single peripheral nerve
area of sensory loss is less than the anatomic distribution of the nerve, loss of sensation is greatest in the central portion
What is the pattern of sensory loss with multiple peripheral nerves
sensory loss is most severe over legs and feet or over hands usually involves all modalities of sensation
What is the pattern of sensory loss with multiple spinal nerve roots
incomplete loss of sensation in any area of the skin usually occurs when once nerve root is affected

if two or more nerve roots affected zone of sensory loss is surrounded by partial loss and possible loss of deep tendon reflex
What is the pattern of sensory loss with complete transverse lesion of the spinal cord?
all forms of sensation of lost below the level of the lesion; pain, temperature and touch sensations are lost one to two dermatomes below the lesion
What is the pattern sensory loss of a partial spinal sensory syndrome?
pain and temperature sensation are lost one to two dermatomes below the lesion on the opposite side of the body from the lesion; proprioceptive loss and motor paralysis occur on the lesion side of the body
What tract provides superficial pain and temperature
lateral spinothalmic
What tract provides superficial touch and deep pressure
anterior spinothalmic
What tract provides vibration, deep pressure, position sense, stereognosis, point location and two point discrimination
posterior column
What tract provides proprioception
anterior and dorsal spinocerebellar
What tract provides rapid rhythmic alternating movement, voluntary movement, deep tendon reflex and plantar reflex
lateral and anterior corticospinal
What tract provides posture and romberg, gait and instinctual motor reactions
medial and lateral reticulospinal
What is the reflex of the upper abdomen
T8, T9, T10
What is the reflex for the lower abdomen
T10, T11, T12
What is the reflex for the cremasteric
T12, L1,, L2
What is the reflex for the plantar
L5, S1, S2
What is the biceps reflex
C5 and C6
What is the brachioradialis reflex
C5 and C6
What is the triceps reflex
C6, C7, C8
What is the patellar reflex
L2, L3, L4
What is the achilles reflex?
S1 and S2
What reaction occurs with abdominal reflex
slight contraction of the umbilicus toward each area of stimulation should occur bilaterally
What reactions occurs with the cremasteric reflex?
testicle and scrotum should rise on the stroked side
What reaction occurs with the plantar reflex ?
Babinski sign
dorsiflexion of great tow with or without fanning of other toes indicates upper motor neuron lesion normally have plantar flexion of toes

reflex present in children under the age of two
How should the limb be positioned to test deep tendon reflexes?
with slight tension on tendon to be tapped
locate correct point on tendon for stimulation
What is the grading scale for deep tendon reflexes?
0= no response
1= sluggish or diminished
2= active or expected response
3= more brisk than expected, slightly hyperactive
4= brisk, hyperactive, with intermittent or transient clonus
What is the expected findings for upper motor neuron lesions?
increased muscle tone and spasticity
little or no muscle atrophy but decreased strength
sensation loss may affect entire limb
hyperactive deep tendon reflexes
positive babinski sign
no fasciculation
paralysis of voluntary movements
damage above brainstem affects contralateral side and below brainstem affects ipsilateral side
What is the expected findings for lower motor neuron lesions?
decreased muscle tone and flaccidity
loss of muscle strength and atrophy
sensory loss following distribution of dermatome
weak or absent reflexes
fasciculation
paralysis of muscle
damage affects ipsilateral side
how do you position the patient for biceps reflex?
flex patients arm to 45 degrees

causes visible or palpable flexion of elbow
How do you position the patient for brachioradialias reflex?
flex to 45 degrees and pronate the hand

pronation of forearm and flexion of elbow should occur
How do you position the patient for the triceps reflex
flex patients arm to 90 degrees supporting arm in antecubital fossa

see visible extension of the elbow
How do you position the patient for the patellar reflex?
flex patients knee to 90 degrees

contraction of quads leads to extension of lower leg
How do you position the patient for the achilles reflex
flex knee to 90 and keep ankle in neutral position

contraction cause plantar flexion of foot
How do you test for clonus?
test when reflexes are hyperactive

have knee partially flexed and briskly dorsiflex the foot with your other hand maintaining the foot in flexion

should see no rhythmic oscillating movements
What do you use to test for protective sensation in patients with DBM and peripheral neuropathy?
5.07 monofilament or Waardenberg wheel
Where do you roll the Waardenberg wheel?
Random pattern in several sites on the plantar surface of the foot and on one site on the dorsal surface
How long should the monofilament be applied to each site?
1.5 seconds, do not repeat sites
How do you know adequate pressure has been applied?
Filament bends
Loss of sensation to the touch of monofilament/ Waardenberg is an indication of what?
Peripheral neuropathy, and hte loss of protective pain sensation that alerts patients to skin breakdown/injury
Nuchal rigidity is a sign of?
Meningitis and intracranial hemorrhage.
How do you test for nuchal rigidity?
Slid hand under head and raise it, flexing the neck. Try to make the patients chin touch sternum.
How do you make the determination of true stiffness more accurate?
Placing hand under shoulders when the patient is lying down and raising the shoulders slightly to help relax the neck.
What else can cause ppain in the neck and resistance to neck motion?
Painful swollen LNs & superficial trauma.
What vaccines reduce the risk of developing meningitis in children?
H. Influenzae type B & pneumococcal vaccine (PCV7)
What is the Brudzinski sign?
Involuntary flexion of hips & knees when flexing the neck indicates meningeal irritation
What is the adult pneumococcal vaccine?
PPV
What is the Kernig sign?
Flexing the leg at the knee and hip when the patient is supine....attempting to straighten the leg. Pain in the low back & resistence to straight leg = positive
What are the symptoms of meningitis?
Fever, heachacke, stiff neck, photophobia, nausea, vomiting
How sensitive/specific are Brudzinski/Kernig signs?
5% Sensitive; 95% specific
What is the positive/negative predictive value of Brudzinski/Kerning signs?
27/72%
How sensitive/specific is nuchal rigidity?
Sensitive 30%; Specific 68%
What is the positive/negative predictive value of nuchal rigidity?
26/73%
What should you observe for in an infant?
Odd facies that may be suggestive of congenital conditions that include neuro problems : low set ears, port wine stains
What spontaneous activity should be observed in an infant?
Symmetry, smoothness of mocement. Coordinated sucking/swallowing.
Hands hare held in fists for how long?
First 3 months
When do hands open for longer periods?
After 3 months
When does purposeful movment occur?
At 2 months = reaching and grasping for objects
When does taking objects with one hand occur?
6 months
WHen does transferring of objects from one hand to another occur?
7 months
When does purposefully releasing objects occur?
10 mo
What reduces risk of SIDS?
Change in sleep position form prone to the back. Encourage supervised tummy time to stimulate gross motor development.
Procedure for CN II, III, IV, VI evalutation in newborns/infants?
Optical blink reflex; Gases intensely at close object or face; Focuses on and tracks an object with both eyes; Doll's eye manuver
Procedure for CN V evaluation in newborns/infants?
Rooting reflex & sucking reflex
Procedure for CN VII evaluation in newborns/infants?
Observe infant's facial expression when crying (wrinkle forehead & symmetry of smile)
Procedure for CN VIII evaluation in newborns/infants?
Acoustic blink reflex; Movement of eyes in direction of sound; Freezes eyes with high-pitched sound; Doll's eye maneuver
What is the acoustic blink reflex?
Loudly clapping hands 30cm from babys head causes them to blink in response to the sound. No response after 2-3 days of age => hearing problems, but if you repeatedly test infant they will become habituated
What is the doll's eye reflex?
Infant held in armpit area in upright position with head facing you => rotate infant in one direction then the other => infants eyes should turn in the direction of rotation and then in the opposite direction when rotation stops. No reflex => vestibular problem/ eye muscle paralysis
Procedure for CN IX and X evaluation in newborns/infants?
Swallowing and gag reflex
Procedure for CN XII evaluation in newborns/infants?
Coordinated sucking/swallowing; pinch infant's nose to see mouth open and tip of tongue rise in midline position
What is the optical blink reflex?
Optical blink reflex: shine a light in open eyes => observe the quick closure of hte eyes and dorsal flexion of the infants head => no response indicates poor light perception
What is the rooting reflex?
Rooting reflex: touch corner of mouth => infant opens mouth and turns head in direction of stimulation => if infant has recently been fed response will be weak/absent
What is the sucking reflex?
Finger in infants mouth => tongue should push up against your finger with good strength; note pattern, strength, pressure of sucking
Seeing a baby withdraw all limbs from a painful stimulus provides measure of?
Sensory integrity
What reflex is present at birth?
Patellar
What reflexes appear at 6mo of age?
Achilles and brachioradialis
What should be used to test reflexes on an infant?
Finger
How many beats are ankle clonus normal?
1 or 2
How many an beats of ankle clonus merit further evaluation?
10 or more
What is a positive Babinski sign?
Fanning of toes and dorsiflextion of great toe
How long is Babnski found in kids?
Until 16-24 mo of age
When evaluating posture and movement, what should you be observing for?
Symmetry & smoothness; rhythmic twitching; sustained asymmetric posturing; paroxysmal episodes of these signs => epilepsy; muscle strength and tone
Delay in sitting or walking is a sign of?
Cerebellar disorder
What is the Denver II?
Tool to determine whether a child is developing as expected: fine/gross motor skills, language, personal-cocial skills
What is the Ages and Stages tool?
A standardized parent questionnaire to assess development.
What do the first stages of walking look like?
Wide-based gait
What does an older child walk like?
Feet are closer together, has better balance, and recovers more easily when unbalanced
What are the coordination skills that develop in a young child?
Heel-to-toe walking, hopping and jumping
What can three pennies be used for in an evaluation?
Gain the child's cooperation and evaluate vision, extraocular movements, and hearing by dropping the coinds on the floor. Asking the child to pick up the pennies tests their vision and balance. Sticking a moist coin to the childs nose and asking them to walk allows for obstervation of gait/posturing.
What penny trick tests Romberg?
Asking the child to balance a penny on the nose and dorsum of each extended hand.
How do you evaluate light touch on a child?
Child closes eyes and points to where you touch/tickle. Have child differentiate between hard/soft textures. Using tuning fork evaluate vibration. No pain testing.
What is the palmar grasp and when is it present?
Birth: Head midline, touch palm of hand from ULNAR side => strong grasp, sucking facilitates grasp. Strongest at 1-2 mo of age, gone by 3mo
What is the plantar grasp and when is it present?
Birth: Touching the plantar surface of hte infants feet at base of toes causes them to curl downwards. Strongest up to 8mo
What is the moro reflex and when is it present?
Birth: Semisitting position => head and trunk drop back to 30 degree angle => symmetric abduction/extension of arms => fingers fan out and thumb/index form a C => arms adduct in an embracing motion and then relax in flextion. Reflex strong at 3-4mo, gone by 6mo
What is the placing reflex and when is it present?
4 days: Holding infant upright touch dorsal side of foot to table edge => flexion of hips & knees & lifting of foot. Dissapearance varies.
What is the stepping reflex and when is it present?
Birth/8 weeks: Holding infant upright allow soles of feet to touch surface of table => alternate flexion and extension of legs (like walking). Dissapears before voluntary walking.
What is the asymmetric tonic neck or "fencing" reflex and when is it present?
2-3mo: Infant lying down, turn head to one side => extension of arm and leg on the side to head turning, flexion of opposite arm/leg => reversal. Diminishes at 3/4mo and disappears by 6mo. If infant doesnt have reflex/ or is locked in reflex => infant may be not able to roll over
What do you use to check cortical sensory integration?
Geometric figures (not numbers) to evaluate graphesthesia. Draw a figure twice and ask child if they are the same or different with eyes closed, and repeat with eyes open.
How do you evaluate CN II in a young child?
Snellen E, HOTV, or picture chart to test vision. Immobilize head for visual field testing.
How do you evaluate CN III, IV, VI in a young child?
Follow object w/ eyes immobilizing head. Move object thorugh H to test EOMI
How do you evaluate CN V in a young child?
Observe child chewing cookie/cracker noting BL jaw strength. Touch cheeks/forehead w cotton or string and watch child bat it away.
How do you evaluate CN VII in a young child?
Observe smiling, frowning, crying. Ask child to show teeth. Have child copy you puffing your cheeks
How do you evaluate CN VIII in a young child?
Observe turning to sounds like bell/whisper. Whisper behind child and have them repeat the word. Audiometric testing.
How do you evaluate CN IX and X in a young child?
Elicit gag reflex
How do you evaluate CN II XI and XII in a young child?
Stick out tongue/ shrug shoulders/ raise arms
What do you start with when doing a neuro exam on a Preggo?
DTR's as baseline
What assessment is essential to determine impact of illness on a patient?
Functional status
What is the leading cause of death and adult disability?
Stroke
What are the lifestyle modifications that can reduce the risk for stroke?
weight reduction, adherence to a diet that is low-fat, low-sodium, and rich in fruits, vegetables, and dairly products, 30 mins of aerobic exercise daily, moderate alcohol consupmtion, no smoking.
What medical conditions can be treated to avoid stroke?
HTN, heart disease, DB, hyperlipidemia, carotid stenosis
What can medications do to the nervous system?
Impaire CNS function, cause slow reaction time, tremors (rhythmic, oscillating, involuntary purposeless movements), and anxiety.
Why do problems with medications develop?
Dosage, number, or interaction of Rx and non-Rx meds
What senses are diminished in an older adult?
Smell and taste, butter and sour go first.
What CN changes occur in an older adult?
Impaired color differentiation, upward gaze, adjustment to light changes, decreased corneal reflex, middle-high frequency hearing loss, reduced gag reflex
What happens to a person's gait with advancing age?
Shorter steops, less lifting of feet (loss of proprioception), shuffeling, decrease of speed/balance/grace. Arms more flexed, legs flexed at hips/knees.
What is a simple screening test for balance/strength/cerebellar fxn?
Arise from a chair without using arms; walk normally; stand with feet together eyes open/closed; stand on heels/toes; sit back down no arms
What is the Tinetti Balance and Gait Assessment tool?
8 positions and position changes are evaluated. 1) sitting balance; 2) rising without arms out of chair; 3) attempts to rise; 4) Immediate standing balance (5sec); 5) Standing balance; 6) Nudged; 7) Eyes closed; 8) Turning 360 degrees; 9) sitting down.....score out of 16
How is sitting balance graded in the tinetti assessment'?
0 = leans or slides in chair; 1= steady, safe
How is rising out of chair graded in the tinetti assessment?
0 = unable without help; 1 = able, uses arms; 2 = able without help
How is attempting to rise graded in the tinetti assessment?
0 = unable without help; 1 = able but requres more than one attempt; 2 = able to arise, one attempt
How is immediate standing balance graded in the tinetti assessment?
0= unsteady; 1 = steady but needs walker/support; 2 = steady without support
How is Standing balance graded in the tinetti assessment?
0 = Unsteady; 1 = Steady but wide stance (heels more than 4in apart)/needs support; 2 = narrow stance without support
How is Nudged graded in the tinetti assessment?
0 = begins to fall; 1 = staggers, grabs, catches self; 2= steady
How is Eyes closed graded in the tinetti assessment?
0 = unsteady; 1 = steady
How is Turning 360 graded in the tinetti assessment?
0 = discontinuous steps/ unsteady; 1 = continuous steps/steady
How is Sitting down graded in the tinetti assessment?
0 = Unsafe (misjudges distance, falls in chair); 1 = Uses arm/unsmooth motion; 2 = safe, smooth motion
What is the Gait Test?
8 components of gait are observed, patient has to walk 10ft normally and then back using rapid pace. 1) initation of gait; 2) step length 3) step height; 4) Step symmetry; 5) step continuity; 6) Path; 7) Trunk; 8) walking stance........gait score of 12
How is initiation of gait graded in the gait assessment?
0 = Any hesitancy or multiple attepmts to start; 1 = no hesitancy
How is step length/height graded in the gait assessment?
0 = Right swing foot does not pass left foot with stance; 1 = passes left stance foot; 0 = right fot does not clear floowr completely with step; 1 = Right foot completely clears floor; 0 = Left swing foot does not pass right stance foot with step; 1 = Passes right stance foot; 0 = Left foot does not clear floor completely with step; 1 = Left foot completely clears floor
How is step symmetry graded in the gait assessment?
0 = Right and left step length not equal (estimate); 1 = Right and left step length appear equal
How is step continuity graded in the gait assessment?
0 = stopping or discontinuity between steps; 1 = steps appear continuous
How is path graded in the gait assessment?
0 = marked deviation; 1 = mild/moderate deviation or uses walking aid; 2 = straight without walking aid
How is trunk graded in the gait assessment?
0 = marked sway or uses walking aid; 1 = No sway, but flexion of knees or back, or spreads arms out (while walking); 2 = No sway, no flexion, no use of arms, and no use of walking aid
How is walking stance graded in the gait assessment?
0 = heels apart; 1 = heels almost touching while walking
What balance and gait score indicates a risk for falls?
Score of < 19
What balance and gait score indicates there is a greater chance of falls but not high risk?
Score of 19-24
How can you observe fine motor abilites in an elderly person?
Observing the patient dress/undress
What are DTR's like in an older adult?
Less brisk or absent reflexes with response diminishing in the LEs before UEs. Achilles/plantar diminished. Superficial reflexes dissapear.
What increases with aging?
Bening essential tremor. Fine motor coordination and agility.
What is a static problem in the nervous system?
Develops at any age and does not get better or worse but the clinical manifestation should change over time (nerve deafness/birth truama)
What is a degenerative condition in the nervous system?
Person was well until function was lost, and it gets worse.
What is MS?
A progressive autoimmune disorder characterized by a combo of inflammation & degneration of myeling of white matter => decreased brain mass/obstructed transmission of nerve impulses
What is the pathophysiology of MS?
Infectious agents triggering autoimmune rxn in susceptible people
When do the symptoms of MS occur?
Btwn 20-40; women twice as often as men
What are the subjective findings in MS?
Fatigue, urinary frequency, urgency, hesitancy, sexual dysfunction, vertigo, weakness, numbness, blurred vision diplopia, loss of vision, emotional changes
What are relapse symptoms like for someone with MS?
Relapse symptoms develop rapidly (hours-days) and take weeks to recede
What would the PE reveal in someone with MS?
Muscle weakness, ataxia, hyperactive DTR, parentheisas/sensory loss, intention tremor, optic neuritis, cognitive changes, MRI lesions
What does the MRI look like for someone with lesions from MS?
Periventricular, ovoid, perpendicular to ventricles; SC lesions may also be found
What is epilepsy?
Chronic disorder characterized by recurrent, unprovoked generalized seizures secondary to underlying brain abnormality.
What causes epilepsy?
Episodic abnormal electical discharges (excessive concurrent firing) of cerebral neurons that can be caused by a disorder, a defect, injury, toxins, brain tumor, hypoxia
What are the subjective findings in epilepsy?
Hx of seizures, premonition/aura, stiff/rigid body, jerking motions, eyes rolling up, drooling, incontinance
What are the phases of a seizure?
Tonic; Clonic; Postictal
What occurs in the tonic phase of a seizure?
Brief flexon, characteristic cry with contractionof abd muscles => generalized extension for 10-15min => loss of conciousness for 1-2 min, eyes deviate up, dilated pupils
What occurs in the clonic phase of a seizure?
Contractions alternate with muscle relaxation
What occurs in the postictal state?
coma followed by confusion/lethargy
What does the EEG look like in epilepsy?
Spikes and waves
What is acute inflammation of hte brain & SC involving the meninges?
Encephalitis = due to virus
What is an inflammatory process in the meninges only?
Meningitis
How does encephalitis occur?
Transmitted by the bite of an arthropod or mosquito, such as WNV, EEE, or japanese encephalitis
What is the cause of meningitis?
The bacterial, viral, or fungal organism often colonizes in the UR tract, invades the bloodstream and then crosses the BBB to infect the CSF and meninges
What are the subjective findings of an episode of encephalitls?
Mild viral illness with fever. Recovery and quiet stage followed by onset of lethargy, restlessness, and mental confusion
What does one find on a PE examining a case of encephalitis?
Altered mental status, confusion, stupor, coma. Photophobia, stiff neck, muscle weakness, paralysis, ataxia
What are the subjective findings in meningitis?
Fever, chills, headache, stiff neck, lethargy, malaise, vomiting, irritability, seizures
What does one find on a PE examining a case of meningitis?
Altered mental status, confusion, nuchal rigidity, fever, Brudzinsky/Kernig signs may be positive, petechiae/purpura, meningococcal meningitis
What confirms the diagnosis of menigitis?
LP and CSF culture
What is mass effect?
Tumor that causes displacement of tissue and pressur on the CSF circulaiton; function is threatened through compression/destruction of tiussues
When is the peak time for prain tumors?
65-79y
What are the subjective findings in somone who has a brain tumor?
Persistent headache, nausea, vomiting, unsteady gait, impaired coordination, memory loss, confusion, reduced vision acuity, visual loss, behavior/personality change, seizure
What brain tumor symptoms occur in children?
Irritability, lethargy, weight loss, growth failure, precocious puberty
What would a PE reveal with a brain tumor?
Altered conciousness, confusion, papilledema, CN impairment, aphasia, langage disorder, vision loss (hemianopia/nystagmus), gait disturbance, taxia
What is a stroke?
Sudden interruption of blood supply to a part of hte brain or the rupture of a BV, spilling blood into spaces round brain cells
What is an ischemic stroke?
Occurs when a thrombus or embolism interrupts the blood supply, oxygen, and nutrients to the brain and brain cells die. (most common cause of stroke)
What causes 15% of hemorrhagic stroke?
Intracerebral or subarachnoid bleeding - distribution of anterior circulation of the brain: brain cells die due to bleeding
What happens to the patient when they are having a stroke?
Get numbness or weakness suddenly; confusion/trouble speaking or understanding speech; trouble seeing in one or both eyes; trouble with walking, dizziness, loss of balance/coordination; sudden severe headache with no known cause
What are the findings in a stroke?
High BP, altered conciousness, difficulty managing secretions, weakness/paralysis of extremities or facial muscles on one/both sides of body; aphasia (receptive/expressive); articulation impairment; impaired horizontal gaze/hemianopia
WHat are the neurologic signs of a blocked internal carotid artery?
Unilateral blindness; severe contralateral hemiplegia/hemianesthesia; profound aphasia
What is the supply of the internal carotid?
splits into opthalmic/ ipsilateral hemisphere arteriess => Cerebral hemispheres; diencephalon
What are the neuro signs of a blocked MCA?
Altered communication, coginition, mobility, sensation; contralateral homonymous hemianopia; contralateral hemiplegia/hemiparesis, motor/sensory loss greater in face & arm than the leg
What is the supply of the MCA?
Frontal, parietal lobes; cortical surface of temporal lobe => communication areas; language, interpretation, perception, interpretation of space, sensation, form, voluntary movement
What is are the neuro signs of a blocked ACA?
Emotional lability; confusion, amnesia, personality changes; urinary incontinence; contralateral hemiplegia/hemiparesis, greater in LE than UE
What are the neuro signs of a blocked PCA?
Hemianesthesia; contralateral hemiplegia, greater in face and UE than in LE; cerebellar ataxia, tremor; visual loss (homonymous/hemianopia/cortical blindness); receptive aphasia; memory deficits
What are the neuro signs of a partial blockage of vertebral/basilar arteries (brainstem/cerebellum supply)?
Transient and ischemic attacks; unilateral/BL weakness of extremities; UMN weakness involving face, tongue, and throat; loss of vibratory sense, 2-point discrimination adn position sense; diplopia, homonymous, hemanopia; nausea, vertigo, tinnitus, syncope; dysphagia, dysarthria; sometimes confusion and drowsiness
What are the neuro signs of a blocked PICA?
Wallenberg syndrome; dysphagia, dysphonia; ipsilateral anesthesia of face/cornea for pain& temp (touch preserved); ipsilateral horner syndrome; contralateral loss of pain & temp sensation in trunk & extremeties; ipsilateral decompensation of movement
What are the neuro signs of a blocked AICA?
Difficulty in articulation, swallowing, gross movements of limbs; nystagmus
What are the neuro signs of a blocked SCA?
Difficulty in articulation, swallowing, gross movements of limbs; nystagmus
What are the neuro signs of a blocked anterior spinal artery?
Flaccid paralysis, below level of lesion; loss of pain, touch, temp sensaton (proprioception perserved)
What are the neuro signs of a blocked posterior spinal artery?
Sensory loss, particularly proprioception, vibration, touch, and pressure (movement preserved)
What are the neuro signs of a blocked vert/basilar (anterior pons supply)?
Locked-in syndrome - no movement except eyelids; sensation and conciousness preserved
What are the neuro signs of vert/basilar (complete occlusion)?
Coma; mitotic pupils; decerebrate rigidity; respiratory and circulatory abnormalities; death
Supply of ACA?
Supplies superior surfaces of frontal/parietal lobes, and medial surface of cerebral hemispheres, BG, corpus callosum => motor/somesthetic cortex serving the legs
Supply of PCA?
Supplies medial/inferior temporal lobes, medial occipital lobe, thalamus, posterior hypothalamus, visual receptive area
Supply of vertebral/basilar arteries?
Brainstem/cerebellum; anterior portion of pons
Supply of PICA?
Lateral/posterior portion of the medulla
Supply of AICA/SCA?
Cerebellum
Supply of anterior spinal artery?
Anterior SC
Supply of posterior spinal artery?
Posterior SC
What is MG?
Autoimmune disorder of NM transmission involving the produciton of autoantibodies directed against the nicotinic Ach recpetor => destruction & inflammatory changes in the postsynaptic membranes
Where is MG confined in 15% of cases?
Ocular muscles
What are the symptoms of MG?
Drooping eyelids; double vision; difficulty swallowing/speaking; fluctuating fatigue/weakness; inability to work with arms raised above head; difficulty walking; symptoms are worse later int he day and improve with rest
What are the objective findings in MG?
Ptosis that develops within 2 min of upward gaze; facial weakness when puffing out cheeks; hypophoia; difficulty managing secretions; repiratory compromise or failure; wekness of skeletal muches without reflex, sensory, or coordination abnormalities
What is guillain-barre?
Autoimmune destruction of peripheral nerve myelin sheaths and inflammation of nerve roots following a GI infection or URI 1-3 weeks earlier or following an immunization
What is the result of Guillain barre?
Impaired condction of nerve impulses between the nodes of Ranvier
What are the subjective findings in Guillain barre?
Hx of recent ilness; progressive weakness (more in legs); difficulty walking; paresthesia; pain in shoulder, back, posterior thigh; double vision
Whate are the objective findings in Guillain barre?
Distal weakness (BL, symmetric, diminished DTR); ataxia; flaccid paralysis; facial nerve weakness (bells palsy); diplopia; dysphagia, difficulty handling secretions; respiratory distress
What is seen in a LP in someone with Guillain barre?
Increased protein
What causes Tic Douloureux?
Small artery that compresses CNV and wears away myelin/irritates afferent portion
When is tic douloureux seen?
40-60y women are more commonly affected than men
What are the symptoms of tic douloureux?
Sharp pain episode on one sie of face (sec-minutes); rarely BL; triggered by: chewing, swallowing, talking, washing the face, brushing teeth, cold exposrue, breeze
How often does tic douloureux strike?
Several times a day, to several times a month followed by a pain-free period
What are the findings in tic douloureux?
Slight sensory impairment in pain regions; facial nerve distribution of pain; most of the time normal neuro exam
What causes Bell's palsy?
Acute inflammation of facial nerve; viral infection (HSV); ischemia/demyelination; CNS lesions (MS, stroke, tumor); structural lesions in ear/parotid gland
Who gets Bell's palsy?
Anyone but more common in diabetes
What causes peripheral neuropathy?
DBM,; altered lipid metabolism; B12/folate deficiency
What polyneuropathies have an autoimmune etiology?
lyme disease; HIV; diabetes
What leads to sensory and autonomic nerve fxn deficits in peripheral neuropathy?
impaired blood flow, vasoconstriction, chronic ischemic changes within peripheral N fibers
What are the symptoms of peripheral neuropathy?
Gradual onset of numbness, tingling, burning, cramping (hands & feet); night pain in both feet; nusual sensations of walking on cotton, floors feel strange, inablilty to distinguish between coins by touch; sensation of burning; hyperalgesia; allodynia
What are the findings in peripheral neuropathy?
Reduced sensation w/ monofilament/waardenberg; loss of pain/sharp touch to mid-calf level; diminished/absent distal pulsse & ankle/knee reflexes; no vibratory sensation below knees, also temp; distal muscle weakness, cant stand on heels/toes; skin ulcerations
What is cerebral palsy?
Permanent disorder of movement and posture development associated with nonprogressive (static) disturbances that occured in the developing fetal or infant brain
What causes CP?
Injury to the immature periventricular white matter in fetuses and premature infants
What else causes CP?
Brain insult from complications of being a preeme; prenatal, perinatal, genetic factors; viral infection of fetus
What are the symptoms of CP?
Delay in gross motor dev; activity limitation; hearing, speech, language disorders; feeding difficulties; seizures
What are the signs of CP?
Mental retardation; learning disabilities
What is spastic CP?
hypertonicity, tremors, scissor gait, toe walking; persistent primitive reflexes, exaggerated DTRs
What is dyskinetic CP?
involuntary slow writhing movements of the extremities; tremors present; exaggerated posturing; inconsistent muscle tone that changes throughout the day
What is ataxic CP?
Abnormalities of movement involving balance and position of trunk/extremities; intention tremors; past pointing; variation in muscle tone; hypotonia as infant; instability & wide-based gait
What is myelomeningocele?
Spina bifida: congenital defect of vertebrae that allows a meningeal sac filled with SC to protrude
What causes SB?
Unknown: excessive use of alcohol, meds for seizures/acne, genetic factors, maternal nutrition
When does SB occur?
.4 to 1.43 per 1000 live births in US; declining with folic acid supplementation
What are the symptoms of SB?
Loss of bowel control/constipation; urinary incontinence/retention; mobility problems
When is the exposed sac apparent in SB?
At birth
Where is sensory deficit and paralyis/weakness present in SB?
Depends on level of defect - higher the defect, greater the dysfunction; may not be symmetric
What are the associated symptoms of SB?
Increasing head circumference = hydrocephalus; hip/foot abnormalities; learning/motor disabilities
What age baby usually sufferes from shaken baby syndrome?
Under 1 year of age
What happens in shaken baby syndrome?
Brain moves around in head => tears nerve tissue and BVs => brain damage/ subdural hematoma/ SC damage with head movement
What are the sings of shaken baby?
Fever, irritability, lethargy, decreased food intake, breathing difficulty/apnea, seizure, losso of conciousness
What alerts the physician to shaken baby syndrome?
BL rentinal hemorrhages with retinal detachments/folds; no truama to head but fingerprint bruises present; bite marks/burns/bruising
What does a CT scan show in shaken baby?
Subdural/subarachnoid hemorrhage
What can an Xray reveal about shaken baby?
Old/new fractures of long bones/ribs
What is intrapartum maternal lumboscaral plexopathy?
Neuropathy that occurs duirng late pregnancy and early delivery
Where does IMLP occur?
Lumbosacral trunk/ superior gluteal/ obturator nerves => get compressed between maternal pelvic rim and fetal head
What are the symptoms of IMLP?
Intermittent pain radiation from butt to leg during late pregnancy. Mom too small; mom has prolonged labor; foot drop after birth
What distribution of pain is a sign of IMLP?
Lumbar 5
How long does IMLP last?
Foot drop may take weeks to resolve
What causes parkinsons disease?
Hx of encephalitis, drug use, CV disease, genetic, environmental, viral, vascular, toxic
Who gets PD?
Over 50 y
What are the symptoms of PD?
Tremor (unilateral) at rest and with fatigue; intended movement and sleep resolve tremor; pill orlling BL of fingers; head tremor; slowing of voluntary/automatic movements; numbness, aching, tingling, muscle soreness
What findings are there in someone with PD?
Tremor, rigidity, stooped posture, instability, short-shuffeling-freezing gait; difficultly swallowing; drooling; sweating; voice softens; slurred, monotonous speech; impaired cognition => dementia
What is normal pressure hydrocephalus?
Syndrome simulating degenerative disease that is caused by noncommunicating hydrocephalus => dilated ventricles with normal ICP
What causes NP hydrocephalus?
Slightly elevated baseline CSF; increased CSF pressure waves OR compression of brain tissue, dcreased cerebral blood flow lead to signs/symptoms
What are the symptoms in NP hydrocephalus?
Gait impairment = 1st symptom! unsteadyness, difficulty turning; cognitive impairment; urinary freq => incontinence
What are the findings in NP hydrocephalus?
Gait impariment, wide based stance, short small steps, reduced clearance during foot swing; NO tremor/sensory impairment; executive fxn IS impaired
What is postpolio syndorme?
Reappearance of neuro signs in survivors of polio epidemics
What makes postpolio syndrome happen?
Damaged neurons sent out axonal links during recovery to activate muscle fibers where neurons were killed by the virus => remaining motor neurons activated many more muscle fibers than they could handle => overloaded/damaged neurons died => recurrance of polio symptoms
What are the symptoms of postpolio syndrome?
Hx of polio in 1950s; reduced muscle strength; increased pain sensitivity; fatigue; need to use assistive devices for mobility; sleep apnea; dysphagia